JP2016515511A5 - - Google Patents
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- JP2016515511A5 JP2016515511A5 JP2016502649A JP2016502649A JP2016515511A5 JP 2016515511 A5 JP2016515511 A5 JP 2016515511A5 JP 2016502649 A JP2016502649 A JP 2016502649A JP 2016502649 A JP2016502649 A JP 2016502649A JP 2016515511 A5 JP2016515511 A5 JP 2016515511A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- cancer
- formulation according
- egfr
- adc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790490P | 2013-03-15 | 2013-03-15 | |
| US61/790,490 | 2013-03-15 | ||
| PCT/US2014/027868 WO2014143765A1 (en) | 2013-03-15 | 2014-03-14 | Anti-egfr antibody drug conjugate formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145641A Division JP2018184468A (ja) | 2013-03-15 | 2018-08-02 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016515511A JP2016515511A (ja) | 2016-05-30 |
| JP2016515511A5 true JP2016515511A5 (enExample) | 2017-04-13 |
| JP6382935B2 JP6382935B2 (ja) | 2018-08-29 |
Family
ID=50680154
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502649A Expired - Fee Related JP6382935B2 (ja) | 2013-03-15 | 2014-03-14 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
| JP2018145641A Pending JP2018184468A (ja) | 2013-03-15 | 2018-08-02 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
| JP2020096643A Pending JP2020143152A (ja) | 2013-03-15 | 2020-06-03 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
| JP2022098605A Pending JP2022126754A (ja) | 2013-03-15 | 2022-06-20 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145641A Pending JP2018184468A (ja) | 2013-03-15 | 2018-08-02 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
| JP2020096643A Pending JP2020143152A (ja) | 2013-03-15 | 2020-06-03 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
| JP2022098605A Pending JP2022126754A (ja) | 2013-03-15 | 2022-06-20 | 抗ｅｇｆｒ抗体薬物複合体製剤 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20140286969A1 (enExample) |
| EP (2) | EP3517132A1 (enExample) |
| JP (4) | JP6382935B2 (enExample) |
| KR (4) | KR102305226B1 (enExample) |
| CN (2) | CN110433139A (enExample) |
| AU (4) | AU2014228172B2 (enExample) |
| BR (1) | BR112015023391A8 (enExample) |
| CA (1) | CA2906130A1 (enExample) |
| CY (1) | CY1121949T1 (enExample) |
| DK (1) | DK2968588T3 (enExample) |
| ES (1) | ES2727134T3 (enExample) |
| HK (1) | HK1219044A1 (enExample) |
| HR (1) | HRP20190672T1 (enExample) |
| HU (1) | HUE044071T2 (enExample) |
| IL (2) | IL241009A0 (enExample) |
| LT (1) | LT2968588T (enExample) |
| ME (1) | ME03457B (enExample) |
| MX (2) | MX2015012549A (enExample) |
| NZ (1) | NZ630826A (enExample) |
| PL (1) | PL2968588T3 (enExample) |
| PT (1) | PT2968588T (enExample) |
| RS (1) | RS58666B1 (enExample) |
| RU (2) | RU2020125266A (enExample) |
| SG (2) | SG11201507430RA (enExample) |
| SI (1) | SI2968588T1 (enExample) |
| TR (1) | TR201905313T4 (enExample) |
| TW (3) | TW201945032A (enExample) |
| WO (1) | WO2014143765A1 (enExample) |
Families Citing this family (49)
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| US9707302B2 (en) * | 2013-07-23 | 2017-07-18 | Immunomedics, Inc. | Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer |
| US10570211B2 (en) | 2011-01-24 | 2020-02-25 | Gilead Sciences, Inc. | Antibodies selective for cells presenting EGFR at high density |
| US20130116404A1 (en) | 2011-11-08 | 2013-05-09 | Case Western Reserve University | Targeted non-invasive imaging probes of egfr expressing cells |
| US11253606B2 (en) | 2013-07-23 | 2022-02-22 | Immunomedics, Inc. | Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer |
| TWI731535B (zh) | 2014-03-21 | 2021-06-21 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
| KR101628872B1 (ko) | 2014-05-28 | 2016-06-09 | 주식회사 레고켐 바이오사이언스 | 자가-희생 기를 포함하는 화합물 |
| CA2965362A1 (en) * | 2014-10-31 | 2016-05-06 | Formation Biologics Inc. | Egfr antibody-based combination therapy |
| US10195175B2 (en) * | 2015-06-25 | 2019-02-05 | Immunomedics, Inc. | Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors |
| WO2017051254A1 (en) * | 2015-09-25 | 2017-03-30 | Legochem Biosciences, Inc. | Compositions and methods related to anti-egfr antibody drug conjugates |
| WO2017051249A1 (en) | 2015-09-25 | 2017-03-30 | Legochem Biosciences, Inc. | Compositions and methods related to anti-cd19 antibody drug conjugates |
| CA3006242A1 (en) | 2015-11-25 | 2017-06-01 | Legochem Biosciences, Inc. | Conjugates comprising self-immolative groups and methods related thereto |
| CA3006247A1 (en) | 2015-11-25 | 2017-06-01 | Legochem Biosciences, Inc. | Conjugates comprising peptide groups and methods related thereto |
| EP3380126A4 (en) | 2015-11-25 | 2019-07-24 | LegoChem Biosciences, Inc. | ANTIBODY-ACTIVE CONJUGATES WITH BRANCHED LINKERS AND ASSOCIATED METHODS |
| CN114177308B (zh) * | 2016-05-17 | 2024-07-09 | 艾伯维生物制药股份有限公司 | 抗cMet抗体药物偶联物及其使用方法 |
| AU2017277534A1 (en) * | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-EGFR antibody drug conjugates |
| JP7054529B2 (ja) * | 2016-06-21 | 2022-04-14 | エックス４ ファーマシューティカルズ， インコーポレイテッド | Ｃｘｃｒ４阻害剤およびその使用 |
| AU2018246806B2 (en) | 2017-03-29 | 2022-05-12 | Ligachem Biosciences Inc. | Pyrrolobenzodiazepine dimer precursor and ligand-linker conjugate compound thereof |
| BR112019025591A2 (pt) * | 2017-06-06 | 2020-06-16 | Jiangsu Hengrui Medicine Co., Ltd. | Composição farmacêutica compreendendo conjugado de fármaco-anticorpo c-met e uso do mesmo |
| BR112020003474A2 (pt) * | 2017-08-23 | 2020-10-20 | Daiichi Sankyo Company, Limited | composição farmacêutica, e, método para produzir uma composição farmacêutica |
| AU2018327171B2 (en) | 2017-08-31 | 2023-03-09 | Daiichi Sankyo Company, Limited | Improved method for producing antibody-drug conjugate |
| WO2019183633A1 (en) | 2018-03-23 | 2019-09-26 | Case Western Reserve Univeristy | Psma targeted conjugate compounds and uses thereof |
| CA3099680A1 (en) | 2018-05-09 | 2019-11-14 | Legochem Biosciences, Inc. | Compositions and methods related to anti-cd19 antibody drug conjugates |
| IL281344B2 (en) | 2018-09-10 | 2025-09-01 | Mirati Therapeutics Inc | Combination of adagrasib and cetuximab for cancer treatment |
| DK3852617T3 (da) * | 2018-09-20 | 2025-10-20 | Sfj Pharma X Inc | Anvendelse af antistof fragmenter til revertering af ticagrelor-aktivitet |
| CN110960490A (zh) * | 2018-09-28 | 2020-04-07 | 江苏恒瑞医药股份有限公司 | 一种抗egfr抗体偶联药物组合物及其用途 |
| SG11202108627SA (en) | 2019-02-18 | 2021-09-29 | Lilly Co Eli | Therapeutic antibody formulation |
| AU2020231509A1 (en) * | 2019-03-04 | 2021-08-19 | Amgen Inc. | In vivo reversibility of high molecular weight species |
| EP4316521B1 (en) * | 2019-03-26 | 2025-06-18 | RemeGen Co., Ltd. | Anti-her2 antibody drug conjugate pharmaceutical preparation |
| CN111939267B (zh) * | 2019-05-17 | 2024-12-20 | 百奥泰生物制药股份有限公司 | 抗体-药物偶联物制剂、制备方法及应用 |
| AU2019341066B1 (en) * | 2019-08-07 | 2021-04-01 | Mabplex International Co., Ltd. | Antibody-drug conjugates and uses thereof |
| KR20210028544A (ko) | 2019-09-04 | 2021-03-12 | 주식회사 레고켐 바이오사이언스 | 인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도 |
| CN112516090B (zh) * | 2019-09-18 | 2023-06-20 | 上海复旦张江生物医药股份有限公司 | 抗体偶联药物的药物组合、冷冻干燥剂及制备方法、用途 |
| TWI885105B (zh) * | 2020-03-25 | 2025-06-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種含抗體藥物偶聯物的醫藥組成物及其用途 |
| CN115605191A (zh) * | 2020-04-10 | 2023-01-13 | 蓝腾制药公司（Us） | 用于治疗脑癌或cns癌症的羟基脲甲基-酰基富烯 |
| KR102683876B1 (ko) * | 2020-11-11 | 2024-07-11 | 가톨릭대학교 산학협력단 | 표적 치료제의 치료 효과 증진을 위한 항체 기반 컨쥬게이트 |
| EP4245319A4 (en) * | 2020-11-11 | 2025-07-02 | Catholic Univ Korea Ind Academic Cooperation Foundation | ANTIBODY-BASED CONJUGATE FOR ENHANCING THE THERAPEUTIC EFFECT OF A TARGETED THERAPEUTIC AGENT |
| CN116761632A (zh) * | 2020-11-11 | 2023-09-15 | 加图立大学校产学协力团 | 用于增强靶向治疗剂的治疗效果的基于抗体的缀合物 |
| CN116635064A (zh) | 2020-12-18 | 2023-08-22 | 世纪治疗股份有限公司 | 具有适应性受体特异性的嵌合抗原受体系统 |
| AR124681A1 (es) | 2021-01-20 | 2023-04-26 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| CN115300623B (zh) * | 2021-05-08 | 2024-06-21 | 盛禾(中国)生物制药有限公司 | 抗egfr融合蛋白或其抗原结合片段的组合物及其用途 |
| WO2022240757A1 (en) | 2021-05-10 | 2022-11-17 | Entrada Therapeutics, Inc. | Antigen-binding and antigen degradation constructs |
| CN115721732B (zh) * | 2021-08-27 | 2025-03-07 | 上海复旦张江生物医药股份有限公司 | 抗体偶联药物的药物组合物、制剂及其制备方法、用途 |
| AU2022388735A1 (en) | 2021-11-09 | 2024-05-30 | Case Western Reserve University | Psma targeted conjugate compounds and uses thereof |
| CN114740108B (zh) * | 2022-03-28 | 2023-07-14 | 天津键凯科技有限公司 | 一种聚合物修饰抗体类药物的修饰度的测定方法 |
| IL317567A (en) * | 2022-06-10 | 2025-02-01 | Acelyrin Inc | ANTI-IGF-1R antibody compounds |
| US20250367311A1 (en) * | 2022-06-15 | 2025-12-04 | Shanghai Hansoh Biomedical Co., Ltd. | Pharmaceutical composition containing an antibody-drug conjugate and use thereof |
| EP4353220A1 (en) * | 2022-10-12 | 2024-04-17 | Pierre Fabre Medicament | Use of a liquid aqueous composition for solubilization and stabilization of an antibody-drug conjugate |
| TW202434307A (zh) | 2023-01-18 | 2024-09-01 | 大陸商泰勵生物科技（上海）有限公司 | 抗體偶聯藥物及其用途 |
| WO2025113442A1 (zh) * | 2023-11-29 | 2025-06-05 | 四川科伦博泰生物医药股份有限公司 | 抗体制剂 |
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-
2014
- 2014-03-14 KR KR1020157029907A patent/KR102305226B1/ko not_active Expired - Fee Related
- 2014-03-14 RS RS20190452A patent/RS58666B1/sr unknown
- 2014-03-14 TW TW108107373A patent/TW201945032A/zh unknown
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