JP2016515382A5 - - Google Patents

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JP2016515382A5
JP2016515382A5 JP2016503223A JP2016503223A JP2016515382A5 JP 2016515382 A5 JP2016515382 A5 JP 2016515382A5 JP 2016503223 A JP2016503223 A JP 2016503223A JP 2016503223 A JP2016503223 A JP 2016503223A JP 2016515382 A5 JP2016515382 A5 JP 2016515382A5
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cells
photoreceptor
cell
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JP6581966B2 (ja
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JP2016503223A 2013-03-15 2014-03-14 多能性幹細胞から生成された光受容体および光受容体前駆体 Active JP6581966B2 (ja)

Applications Claiming Priority (3)

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US201361793168P 2013-03-15 2013-03-15
US61/793,168 2013-03-15
PCT/US2014/029790 WO2014145108A1 (en) 2013-03-15 2014-03-14 Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells

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JP2019159491A Division JP7245752B2 (ja) 2013-03-15 2019-09-02 多能性幹細胞から生成された光受容体および光受容体前駆体

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JP2016515382A JP2016515382A (ja) 2016-05-30
JP2016515382A5 true JP2016515382A5 (https=) 2017-04-20
JP6581966B2 JP6581966B2 (ja) 2019-09-25

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JP2016503223A Active JP6581966B2 (ja) 2013-03-15 2014-03-14 多能性幹細胞から生成された光受容体および光受容体前駆体
JP2019159491A Active JP7245752B2 (ja) 2013-03-15 2019-09-02 多能性幹細胞から生成された光受容体および光受容体前駆体
JP2021162946A Pending JP2022023092A (ja) 2013-03-15 2021-10-01 多能性幹細胞から生成された光受容体および光受容体前駆体
JP2023203590A Pending JP2024053564A (ja) 2013-03-15 2023-12-01 多能性幹細胞から生成された光受容体および光受容体前駆体

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JP2019159491A Active JP7245752B2 (ja) 2013-03-15 2019-09-02 多能性幹細胞から生成された光受容体および光受容体前駆体
JP2021162946A Pending JP2022023092A (ja) 2013-03-15 2021-10-01 多能性幹細胞から生成された光受容体および光受容体前駆体
JP2023203590A Pending JP2024053564A (ja) 2013-03-15 2023-12-01 多能性幹細胞から生成された光受容体および光受容体前駆体

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US (5) US20160030490A1 (https=)
EP (2) EP4292600A3 (https=)
JP (4) JP6581966B2 (https=)
KR (3) KR102527507B1 (https=)
CN (2) CN105378070A (https=)
AU (4) AU2014233403B2 (https=)
CA (2) CA2906815A1 (https=)
DK (1) DK2970903T3 (https=)
ES (1) ES2970720T3 (https=)
FI (1) FI2970903T3 (https=)
HK (1) HK1222205A1 (https=)
IL (5) IL307568A (https=)
PT (1) PT2970903T (https=)
WO (1) WO2014145108A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
EP4292600A3 (en) 2013-03-15 2024-04-10 Astellas Institute for Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
SG10201907918VA (en) 2015-03-23 2019-10-30 Astellas Inst For Regenerative Medicine Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors
TWI711455B (zh) * 2015-05-13 2020-12-01 臺北榮民總醫院 多層視網膜細胞移植物
CN108697641A (zh) 2015-08-18 2018-10-23 安斯泰来再生医药协会 临床制剂
SG11201801770VA (en) * 2015-09-08 2018-04-27 Sumitomo Dainippon Pharma Co Ltd Method for producing retinal pigment epithelial cells
CN105567635A (zh) * 2016-02-21 2016-05-11 中国医科大学附属第一医院 一种改良的Neurobasal B27培养基、制备方法及应用
WO2017173064A1 (en) 2016-03-30 2017-10-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
KR102638492B1 (ko) * 2017-02-17 2024-02-19 쏘흐본느 유니베흐시테 망막 전구 세포, 망막 색소 상피 세포 및 신경 망막 세포를 얻기 위한 피더-비의존적(Feeder-free) 방법
GB201703058D0 (en) * 2017-02-24 2017-04-12 Ucl Business Plc Biomarkers
WO2018164240A1 (ja) 2017-03-08 2018-09-13 大日本住友製薬株式会社 網膜色素上皮細胞の製造方法
US12090252B2 (en) 2017-09-14 2024-09-17 Riken Method for producing retinal tissues
CA3075883A1 (en) * 2017-09-14 2019-03-21 Riken Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter
WO2019078781A1 (en) 2017-10-17 2019-04-25 National University Of Singapore SYSTEMS AND METHODS FOR PRODUCING PHOTORECEPTOR PROGENITORS
JP2021521792A (ja) 2018-04-20 2021-08-30 フジフィルム セルラー ダイナミクス,インコーポレイテッド 眼球細胞の分化方法及びその使用
CN108795864B (zh) * 2018-05-24 2021-08-24 中山大学中山眼科中心 一种利用人诱导多能干细胞获得富含视锥及视杆细胞的类视网膜组织的方法
EP3847244B1 (en) * 2018-09-07 2025-07-30 Hebecell Corporation Methods and compositions for retinal neuron generation in carrier-free 3d sphere suspension culture
US12365872B2 (en) 2018-09-19 2025-07-22 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
CN109486766B (zh) * 2018-11-26 2021-05-07 中山大学 一种泪腺干细胞、泪腺干细胞的培养体系和培养方法
KR20260020476A (ko) 2019-01-23 2026-02-11 아스테리아스 바이오세라퓨틱스, 인크. 인간 만능 줄기 세포로부터의 배측-유래된 희소돌기아교세포 전구 세포
BR112022024064A2 (pt) * 2020-05-29 2023-01-31 Fujifilm Cellular Dynamics Inc Bicamada de epitélio pigmentado da retina e fotorreceptores e uso dos mesmos
US20230201267A1 (en) * 2020-05-29 2023-06-29 FUJIFILM Cellular Dynamics, Inc. Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof
CN112608883B (zh) * 2020-12-25 2023-02-24 武汉睿健医药科技有限公司 一种光感受器神经元细胞的化学诱导方法
EP4269564A4 (en) * 2020-12-25 2025-03-05 Iregene Therapeutics Ltd CHEMICAL INDUCTION METHOD FOR PHOTORECEPTOR NEURONAL CELLS
KR102525093B1 (ko) * 2021-04-16 2023-04-27 가톨릭대학교 산학협력단 사람 신경능 유래 코 하비갑개 줄기세포를 유효성분으로 포함하는 망막변성질환 예방 또는 치료용 약학적 조성물
CN113388582A (zh) * 2021-06-21 2021-09-14 香港再生医学有限公司 促使iPSC分化为外周神经干细胞的方法及培养基和系统

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750196B1 (en) 1995-03-27 2004-06-15 Acorda Therapeutics Methods of treating disorders of the eye
US20030166276A1 (en) 2000-10-16 2003-09-04 Melissa Carpenter Cultures of human CNS neural stem cells
AU3964799A (en) 1998-04-24 1999-11-16 University Of Nebraska Board Of Regents Compositions and methods for the characterization and transplantation of mammalian retinal stem cells
CA2377906A1 (en) 1999-07-16 2001-01-25 Prescient Neuropharma Inc. Methods for producing and preparing cells for cell therapy
WO2002074176A1 (en) 2001-03-16 2002-09-26 University Of Washington Methods for modulating neural activity in the retina
CA2452233A1 (en) 2001-03-26 2002-10-03 Zymogenetics, Inc. Method of inducing proliferation of retinal stem cells
AU2003249227A1 (en) 2002-07-12 2004-02-02 University Of Washington Methods and systems for extended in vitro culture of neuronal cells
EP2929782A1 (en) 2004-01-23 2015-10-14 Ocata Therapeutics, Inc. Improved modalities for the treatment of degenerative diseases of the retina
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
WO2005123902A1 (ja) 2004-06-18 2005-12-29 Riken 無血清浮遊培養による胚性幹細胞の神経分化誘導法
WO2006044204A2 (en) * 2004-10-05 2006-04-27 University Of Georgia Research Foundation, Inc. Neuronal progenitors from feeder-free human embryonic stem cell culture
US7541186B2 (en) 2006-02-22 2009-06-02 University Of Washington Method of generating human retinal progenitors from embryonic stem cells
US20100136537A1 (en) 2006-10-10 2010-06-03 The Regents Of The University Of Michigan Photoreceptor precursor cells
EP2128244A4 (en) 2007-01-18 2012-05-09 Riken PROCESS FOR INDUCTION / DIFFERENTIATION TO A PHOTOREZEPTORZELLE
EP2470645B1 (en) * 2009-08-24 2019-06-26 Wisconsin Alumni Research Foundation Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same
EP2486126B1 (en) * 2009-10-06 2017-12-06 SNU R & DB Foundation Method for differentiation into retinal cells from stem cells
JP5787370B2 (ja) 2009-11-05 2015-09-30 国立研究開発法人理化学研究所 幹細胞の分化誘導方法
ES2542226T3 (es) 2010-04-28 2015-08-03 Technische Universität Dresden Método para producir células progenitoras retinianas polarizadas a partir de células madre pluripotentes y su diferenciación para dar células del epitelio pigmentario retiniano
CA2835215C (en) 2011-05-18 2023-10-10 The Regents Of The University Of California Non-immortal human retinal cell compositions, method for preparing them, and their use for treating retinal diseases
EP2784152B1 (en) 2011-11-25 2019-04-10 Sumitomo Chemical Company, Limited Methods for producing retinal tissue and retina-related cell
SG11201407768QA (en) 2012-04-24 2015-01-29 Brigham & Womens Hospital Generating pluripotent cells de novo
US9458428B2 (en) * 2012-06-05 2016-10-04 The Regents Of The University Of California Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells
CN104508125B (zh) 2012-06-08 2020-06-16 住友化学株式会社 用于产生睫状边缘带样结构的方法
US20140004086A1 (en) 2012-06-29 2014-01-02 Tissue Genesis Inc. Formation of cell aggregates
US20160175361A1 (en) 2014-03-14 2016-06-23 Advanced Cell Technology, Inc. Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
EP4292600A3 (en) 2013-03-15 2024-04-10 Astellas Institute for Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US20160175362A1 (en) 2014-03-14 2016-06-23 Ocata Therapeutics, Inc. Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
EP2796545A1 (en) 2013-04-26 2014-10-29 Université Pierre et Marie Curie (Paris 6) Methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells
KR102278978B1 (ko) 2013-08-23 2021-07-19 스미또모 가가꾸 가부시끼가이샤 망막 조직 및 망막 관련 세포의 제조 방법
EP3070162B1 (en) 2013-11-11 2019-09-18 Sumitomo Chemical Company, Limited Method for producing retinal pigment epithelial cells
JP6495830B2 (ja) 2013-12-11 2019-04-03 住友化学株式会社 毛様体周縁部様構造体の製造法
WO2015109148A1 (en) 2014-01-16 2015-07-23 The Johns Hopkins University Methods for forming three-dimensional human retinal tissue in vitro
KR102368751B1 (ko) 2014-01-17 2022-03-03 스미또모 가가꾸 가부시끼가이샤 모양체 주연부 간세포의 제조 방법
GB201402692D0 (en) 2014-02-16 2014-04-02 Univ Newcastle Synthetic retina
EP3211071B1 (en) 2014-10-24 2021-05-05 Sumitomo Dainippon Pharma Co., Ltd. Production method for retinal tissue
WO2016160718A1 (en) 2015-03-27 2016-10-06 University Of Washington Methods for treatment of retinal disease by photoreceptor gene expression modulation
US12385008B2 (en) 2015-09-08 2025-08-12 Sumitomo Pharma Co., Ltd. Method for producing retinal tissue
US11371003B2 (en) 2016-02-05 2022-06-28 Wisconsin Alumni Research Foundation Photoreceptor scaffold for in vitro modeling and transplantation therapy
WO2017176810A1 (en) 2016-04-04 2017-10-12 Biotime, Inc. Pluripotent stem cell-derived 3d retinal tissue and uses thereof
SG11201809201UA (en) 2016-04-22 2018-11-29 Sumitomo Dainippon Pharma Co Ltd Method for producing retinal tissue
JP7048585B2 (ja) 2016-09-22 2022-04-05 ソルボンヌ・ユニヴェルシテ 網膜変性疾患の処置に使用するための光遺伝学的に形質転換した光受容体前駆細胞
US10973855B2 (en) 2016-10-10 2021-04-13 Small Kent W Methods for treating macular degeneration
MY199613A (en) 2016-11-25 2023-11-09 Riken Cell population for transplantation and method for producing same
US20200138563A1 (en) 2017-01-13 2020-05-07 The Johns Hopkins University Retina regeneration with a tissue-and-technology prosthesis
KR102638492B1 (ko) 2017-02-17 2024-02-19 쏘흐본느 유니베흐시테 망막 전구 세포, 망막 색소 상피 세포 및 신경 망막 세포를 얻기 위한 피더-비의존적(Feeder-free) 방법
GB201703058D0 (en) 2017-02-24 2017-04-12 Ucl Business Plc Biomarkers
EP3656852B1 (en) 2017-07-20 2025-09-03 Riken Method for maturation of retinal tissue containing continuous epithelium
JP2020530839A (ja) 2017-07-31 2020-10-29 バイオタイム インコーポレイテッド 疾患または外傷性損傷を原因とする視覚喪失を回復させるまたは予防するための組成物および方法
JP2020530459A (ja) 2017-08-10 2020-10-22 ユニヴァーシティ オブ ワシントン 網膜の疾患を処置するための光受容体遺伝子のモジュレーターであるフォトレギュリン3
US12090252B2 (en) 2017-09-14 2024-09-17 Riken Method for producing retinal tissues
CA3075883A1 (en) 2017-09-14 2019-03-21 Riken Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter
GB201800546D0 (en) 2018-01-12 2018-02-28 Ucl Business Plc Treatment
US12497591B2 (en) 2018-03-07 2025-12-16 Sorbonne Universite Compositions and methods for efficient amplification of retinal progenitors cells
US20210228741A1 (en) 2018-04-27 2021-07-29 University Of Washington Methods and compositions to stimulate retinal regeneration
US20210317403A1 (en) 2018-05-09 2021-10-14 The Regents Of The University Of Colorado, A Body Corporate Stem cell-derived cell cultures, stem cell-derived three dimensional tissue products, and methods of making and using the same

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