JP2016508776A5 - - Google Patents
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- JP2016508776A5 JP2016508776A5 JP2015555743A JP2015555743A JP2016508776A5 JP 2016508776 A5 JP2016508776 A5 JP 2016508776A5 JP 2015555743 A JP2015555743 A JP 2015555743A JP 2015555743 A JP2015555743 A JP 2015555743A JP 2016508776 A5 JP2016508776 A5 JP 2016508776A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- substrate
- alkene
- present
- hydrophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims description 61
- 239000000758 substrate Substances 0.000 claims description 46
- 150000001336 alkenes Chemical class 0.000 claims description 40
- 125000002355 alkine group Chemical group 0.000 claims description 40
- 239000011248 coating agent Substances 0.000 claims description 30
- 238000000576 coating method Methods 0.000 claims description 30
- 239000002202 Polyethylene glycol Substances 0.000 claims description 29
- 239000000463 material Substances 0.000 claims description 29
- 229920001223 polyethylene glycol Polymers 0.000 claims description 29
- 239000000126 substance Substances 0.000 claims description 23
- 229920001477 hydrophilic polymer Polymers 0.000 claims description 22
- 229920001577 copolymer Polymers 0.000 claims description 20
- 229920001451 polypropylene glycol Polymers 0.000 claims description 18
- 229920000642 polymer Polymers 0.000 claims description 15
- 230000009286 beneficial effect Effects 0.000 claims description 14
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 13
- 125000000524 functional group Chemical group 0.000 claims description 9
- 230000000144 pharmacologic effect Effects 0.000 claims description 9
- 229920001690 polydopamine Polymers 0.000 claims description 9
- 230000002792 vascular Effects 0.000 claims description 9
- 239000003999 initiator Substances 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 239000000178 monomer Substances 0.000 claims description 7
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 6
- 239000004971 Cross linker Substances 0.000 claims description 6
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 6
- 239000000853 adhesive Substances 0.000 claims description 6
- 230000001070 adhesive effect Effects 0.000 claims description 6
- 229920000570 polyether Polymers 0.000 claims description 6
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 6
- 125000003396 thiol group Chemical class [H]S* 0.000 claims description 6
- VEEGZPWAAPPXRB-BJMVGYQFSA-N (3e)-3-(1h-imidazol-5-ylmethylidene)-1h-indol-2-one Chemical compound O=C1NC2=CC=CC=C2\C1=C/C1=CN=CN1 VEEGZPWAAPPXRB-BJMVGYQFSA-N 0.000 claims description 5
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 5
- 229940121369 angiogenesis inhibitor Drugs 0.000 claims description 5
- 239000004037 angiogenesis inhibitor Substances 0.000 claims description 5
- 239000003242 anti bacterial agent Substances 0.000 claims description 5
- 230000001028 anti-proliverative effect Effects 0.000 claims description 5
- 239000003146 anticoagulant agent Substances 0.000 claims description 5
- 229960004676 antithrombotic agent Drugs 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000010526 radical polymerization reaction Methods 0.000 claims description 5
- 239000007791 liquid phase Substances 0.000 claims description 4
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 claims description 4
- 150000003573 thiols Chemical class 0.000 claims description 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims description 3
- 208000005189 Embolism Diseases 0.000 claims description 3
- 229930194542 Keto Natural products 0.000 claims description 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 3
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 125000003172 aldehyde group Chemical group 0.000 claims description 3
- 239000002473 artificial blood Substances 0.000 claims description 3
- 239000008280 blood Substances 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 3
- 230000000747 cardiac effect Effects 0.000 claims description 3
- 230000002612 cardiopulmonary effect Effects 0.000 claims description 3
- 238000012377 drug delivery Methods 0.000 claims description 3
- 230000003073 embolic effect Effects 0.000 claims description 3
- 150000002148 esters Chemical class 0.000 claims description 3
- 238000001631 haemodialysis Methods 0.000 claims description 3
- 210000003709 heart valve Anatomy 0.000 claims description 3
- 230000000322 hemodialysis Effects 0.000 claims description 3
- 229920002674 hyaluronan Polymers 0.000 claims description 3
- 229960003160 hyaluronic acid Drugs 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 3
- 125000000468 ketone group Chemical group 0.000 claims description 3
- 238000012806 monitoring device Methods 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 230000000977 initiatory effect Effects 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 241001631457 Cannula Species 0.000 claims 1
- IVVMYMCCLPZNRL-UHFFFAOYSA-N hydrazinylphosphonic acid Chemical compound NNP(O)(O)=O IVVMYMCCLPZNRL-UHFFFAOYSA-N 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 125000004386 diacrylate group Chemical group 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 125000002009 alkene group Chemical group 0.000 description 4
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 description 4
- 239000012965 benzophenone Substances 0.000 description 4
- 239000006258 conductive agent Substances 0.000 description 4
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical class C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 150000002170 ethers Chemical class 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- YRHRIQCWCFGUEQ-UHFFFAOYSA-N thioxanthen-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3SC2=C1 YRHRIQCWCFGUEQ-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- JNELGWHKGNBSMD-UHFFFAOYSA-N xanthone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3OC2=C1 JNELGWHKGNBSMD-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical group OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 229960003638 dopamine Drugs 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 125000004151 quinonyl group Chemical group 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361760258P | 2013-02-04 | 2013-02-04 | |
| US61/760,258 | 2013-02-04 | ||
| EP13156858 | 2013-02-26 | ||
| EP13156858.6 | 2013-02-26 | ||
| PCT/EP2014/052089 WO2014118382A1 (en) | 2013-02-04 | 2014-02-04 | Coating for substrate |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018170414A Division JP6781220B2 (ja) | 2013-02-04 | 2018-09-12 | 基板用コーティング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508776A JP2016508776A (ja) | 2016-03-24 |
| JP2016508776A5 true JP2016508776A5 (https=) | 2017-03-09 |
| JP6679311B2 JP6679311B2 (ja) | 2020-04-15 |
Family
ID=47750529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015555743A Active JP6679311B2 (ja) | 2013-02-04 | 2014-02-04 | 基板用コーティング |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2950832B1 (https=) |
| JP (1) | JP6679311B2 (https=) |
| KR (1) | KR102247959B1 (https=) |
| CN (1) | CN104936626B (https=) |
| AU (2) | AU2014211351B2 (https=) |
| BR (1) | BR112015017062B1 (https=) |
| CA (1) | CA2897127C (https=) |
| ES (1) | ES2692150T3 (https=) |
| RU (1) | RU2698315C2 (https=) |
| WO (1) | WO2014118382A1 (https=) |
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| JP6781220B2 (ja) * | 2013-02-04 | 2020-11-04 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティドＷ．Ｌ． Ｇｏｒｅ ＆ Ａｓｓｏｃｉａｔｅｓ， Ｉｎｃｏｒｐｏｒａｔｅｄ | 基板用コーティング |
| US11459434B2 (en) * | 2015-05-26 | 2022-10-04 | The University Of British Columbia | Antifouling polymeric coating compositions |
| CN106710407A (zh) * | 2015-07-30 | 2017-05-24 | 上海微创医疗器械（集团）有限公司 | 血管模型及其制作方法、制作该血管模型的设备 |
| EP3356485B1 (en) * | 2015-09-30 | 2020-08-05 | 3M Innovative Properties Company | Hydrogel compositions bonded to polymeric substrates |
| WO2017188214A1 (ja) * | 2016-04-25 | 2017-11-02 | 学校法人早稲田大学 | 高い接着性を有する非水溶性自立性薄膜 |
| CN107478790A (zh) * | 2016-06-08 | 2017-12-15 | 中国石油化工股份有限公司 | 表面附有聚多巴胺亲水层的聚氨酯载体及其制备方法与应用 |
| CN105964014B (zh) * | 2016-06-28 | 2018-05-15 | 西北大学 | 一种亲水/疏油型油水分离不锈钢网膜的制备方法 |
| CN106239949A (zh) * | 2016-07-25 | 2016-12-21 | 成都嘉宝祥生物科技有限公司 | 一种颅脑引流管制造方法 |
| US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
| WO2018061916A1 (ja) * | 2016-09-30 | 2018-04-05 | 東レ株式会社 | 共重合体及びこれを用いた医療材料 |
| KR101861013B1 (ko) * | 2016-10-18 | 2018-05-25 | 주식회사 제낙스 | 도파민계 단량체가 표면중합된 금속 부직포 전극 및 이를 위한 표면 개질 방법 |
| CN106750462B (zh) * | 2016-12-19 | 2019-11-08 | 大连理工大学 | 一种多巴胺及其衍生物聚合并交联固化的表面改性方法 |
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| US11278639B2 (en) | 2017-03-29 | 2022-03-22 | 3M Innovative Properties Company | Hydrogel compositions bonded to polymeric substrates |
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| CN107899078A (zh) * | 2017-10-26 | 2018-04-13 | 华南理工大学 | 一种在三维支架表面共价键合生物活性层的方法 |
| CN107693838A (zh) * | 2017-11-09 | 2018-02-16 | 杭州亚慧生物科技有限公司 | 一种医用可注射凝胶及其制备方法 |
| KR102369383B1 (ko) * | 2017-12-07 | 2022-02-28 | 주식회사 엘지화학 | 카르본산 변성 니트릴계 공중합체 라텍스, 이의 제조방법, 이를 포함하는 딥 성형용 라텍스 조성물 및 이로부터 성형된 성형품 |
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| JP7086202B2 (ja) * | 2018-09-27 | 2022-06-17 | 富士フイルム株式会社 | 生体物質非接着性材料、組成物および化合物 |
| US20220001354A1 (en) * | 2018-11-16 | 2022-01-06 | Nittetsu Mining Co., Ltd. | Coating solution |
| KR102703771B1 (ko) * | 2018-11-30 | 2024-09-04 | 삼성전기주식회사 | 표면처리용 조성물 및 이를 이용한 표면처리방법 |
| KR102778432B1 (ko) * | 2019-06-13 | 2025-03-11 | 재단법인 아산사회복지재단 | 항균성 스텐트 및 이의 제조방법 |
| CN112294695B (zh) * | 2019-08-02 | 2022-08-05 | 万华化学集团股份有限公司 | 一种基于聚多巴胺包裹水性聚氨酯分散体的水性指甲油 |
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| TWI777158B (zh) * | 2019-09-23 | 2022-09-11 | 明志科技大學 | 製備導電性高分子及移除親蛋白尿毒素的方法、導電性奈米纖維塗層及生物電子介面裝置 |
| CN112933301B (zh) * | 2019-11-26 | 2023-01-24 | 上海微创医疗器械（集团）有限公司 | 载药植入医疗器械及其制备方法 |
| WO2021106485A1 (ja) | 2019-11-27 | 2021-06-03 | 株式会社スリーボンド | プライマー組成物 |
| EP3888716A1 (en) * | 2020-04-03 | 2021-10-06 | Tractivus SL | Coating for a device |
| CN111440653B (zh) * | 2020-04-17 | 2021-11-30 | 清华大学 | 聚多巴胺纳米颗粒在水基润滑液中的应用 |
| CA3186706A1 (en) * | 2020-06-10 | 2021-12-16 | Novelis Inc. | Pretreatment compositions bonded to metal substrates and methods of making the same |
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| TR202100462A2 (tr) * | 2021-01-13 | 2021-01-21 | Univ Istanbul Teknik | Görünür Bölge Işığı Altında pH'dan Bağımsız Polidopamin Sentez Yöntemi |
| CN113181424B (zh) * | 2021-04-01 | 2022-03-25 | 中国科学院兰州化学物理研究所 | 一种超分子水凝胶复合润滑抗菌涂层材料的制备方法 |
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| IES20030294A2 (en) * | 2003-04-17 | 2004-10-20 | Medtronic Vascular Connaught | Coating for biomedical devices |
| DE102004043908A1 (de) * | 2004-09-10 | 2006-03-30 | GRÄTER, Stefan | Oberflächenstrukturierte polymere Substrate und ihre Herstellung |
| JP5324100B2 (ja) * | 2004-11-29 | 2013-10-23 | ディーエスエム アイピー アセッツ ビー．ブイ． | ポリマーコーティングに含まれる移行性物質の量を減少させる方法 |
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| ES2387699T3 (es) * | 2007-02-28 | 2012-09-28 | Dsm Ip Assets B.V. | Recubrimiento hidrófilo |
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| WO2011005258A1 (en) | 2009-07-09 | 2011-01-13 | Board Of Regents, The University Of Texas System | Polymer deposition and modification of membranes for fouling resistance |
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| RU2553430C2 (ru) * | 2009-07-31 | 2015-06-10 | Колопласт А/С | Медицинское устройство из полиолефина |
| CN102947376B (zh) * | 2010-06-16 | 2015-04-29 | 帝斯曼知识产权资产管理有限公司 | 用于制备亲水性涂层的涂料配制品 |
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| EP2683420B1 (en) | 2011-03-11 | 2018-05-23 | W. L. Gore & Associates, Inc. | Improvements to immobilised biological entities |
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2014
- 2014-02-04 AU AU2014211351A patent/AU2014211351B2/en active Active
- 2014-02-04 RU RU2015137714A patent/RU2698315C2/ru active
- 2014-02-04 ES ES14702592.8T patent/ES2692150T3/es active Active
- 2014-02-04 CA CA2897127A patent/CA2897127C/en active Active
- 2014-02-04 WO PCT/EP2014/052089 patent/WO2014118382A1/en not_active Ceased
- 2014-02-04 BR BR112015017062A patent/BR112015017062B1/pt not_active IP Right Cessation
- 2014-02-04 EP EP14702592.8A patent/EP2950832B1/en active Active
- 2014-02-04 CN CN201480005686.1A patent/CN104936626B/zh active Active
- 2014-02-04 JP JP2015555743A patent/JP6679311B2/ja active Active
- 2014-02-04 KR KR1020157020179A patent/KR102247959B1/ko active Active
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2017
- 2017-07-13 AU AU2017204779A patent/AU2017204779B2/en active Active
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