JP2016508492A5 - - Google Patents
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- Publication number
- JP2016508492A5 JP2016508492A5 JP2015555678A JP2015555678A JP2016508492A5 JP 2016508492 A5 JP2016508492 A5 JP 2016508492A5 JP 2015555678 A JP2015555678 A JP 2015555678A JP 2015555678 A JP2015555678 A JP 2015555678A JP 2016508492 A5 JP2016508492 A5 JP 2016508492A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally
- substituted
- alkyl
- haloalkyl
- haloalkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000001875 compounds Chemical class 0.000 claims description 37
- 229910052736 halogen Inorganic materials 0.000 claims description 37
- 150000002367 halogens Chemical class 0.000 claims description 37
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims description 32
- 125000000217 alkyl group Chemical group 0.000 claims description 32
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 31
- -1 nitro, hydroxy Chemical group 0.000 claims description 25
- 229910052799 carbon Inorganic materials 0.000 claims description 24
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims description 22
- 125000003545 alkoxy group Chemical group 0.000 claims description 17
- 125000003118 aryl group Chemical group 0.000 claims description 17
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 16
- 125000001424 substituent group Chemical group 0.000 claims description 15
- 125000001425 triazolyl group Chemical group 0.000 claims description 15
- 229910052739 hydrogen Inorganic materials 0.000 claims description 13
- 239000001257 hydrogen Substances 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 13
- 229910052760 oxygen Inorganic materials 0.000 claims description 13
- 239000001301 oxygen Substances 0.000 claims description 13
- 150000001721 carbon Chemical group 0.000 claims description 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 11
- 125000004438 haloalkoxy group Chemical group 0.000 claims description 11
- 125000001072 heteroaryl group Chemical group 0.000 claims description 11
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 10
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims description 9
- 150000002431 hydrogen Chemical class 0.000 claims description 9
- 125000002883 imidazolyl group Chemical group 0.000 claims description 9
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 7
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims description 6
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 6
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 6
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 6
- 230000003032 phytopathogenic effect Effects 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 5
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- 125000002971 oxazolyl group Chemical group 0.000 claims description 5
- 229910052717 sulfur Inorganic materials 0.000 claims description 5
- 239000011593 sulfur Substances 0.000 claims description 5
- 125000003831 tetrazolyl group Chemical group 0.000 claims description 5
- 125000000335 thiazolyl group Chemical group 0.000 claims description 5
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 4
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 4
- 239000000460 chlorine Substances 0.000 claims description 4
- 229910052801 chlorine Inorganic materials 0.000 claims description 4
- 201000010099 disease Diseases 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 4
- 239000011737 fluorine Substances 0.000 claims description 4
- 229910052731 fluorine Inorganic materials 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 244000005700 microbiome Species 0.000 claims description 4
- 230000000844 anti-bacterial effect Effects 0.000 claims description 3
- 125000001188 haloalkyl group Chemical group 0.000 claims description 3
- 125000002950 monocyclic group Chemical group 0.000 claims description 3
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims description 3
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 3
- 206010061217 Infestation Diseases 0.000 claims description 2
- 244000038559 crop plants Species 0.000 claims description 2
- 125000004076 pyridyl group Chemical group 0.000 claims description 2
- 244000045561 useful plants Species 0.000 claims description 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 4
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 description 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 2
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 2
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 description 1
- 150000001204 N-oxides Chemical class 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000001012 protector Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13153924 | 2013-02-04 | ||
| EP13153924.9 | 2013-02-04 | ||
| PCT/EP2014/051621 WO2014118170A1 (en) | 2013-02-04 | 2014-01-28 | Novel microbiocides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508492A JP2016508492A (ja) | 2016-03-22 |
| JP2016508492A5 true JP2016508492A5 (enExample) | 2017-03-02 |
| JP6404235B2 JP6404235B2 (ja) | 2018-10-10 |
Family
ID=47664189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015555678A Expired - Fee Related JP6404235B2 (ja) | 2013-02-04 | 2014-01-28 | 新規な殺微生物剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9655363B2 (enExample) |
| EP (1) | EP2951167B1 (enExample) |
| JP (1) | JP6404235B2 (enExample) |
| CN (1) | CN105102443B (enExample) |
| AR (1) | AR095137A1 (enExample) |
| BR (1) | BR112015018547A2 (enExample) |
| ES (1) | ES2621386T3 (enExample) |
| TW (1) | TW201441215A (enExample) |
| UY (1) | UY35295A (enExample) |
| WO (1) | WO2014118170A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016050769A1 (en) | 2014-10-02 | 2016-04-07 | Bayer Cropscience Aktiengesellschaft | Novel triazole derivatives useful as fungicides |
| EP3277666A1 (en) * | 2015-04-02 | 2018-02-07 | Bayer CropScience Aktiengesellschaft | Novel 5-substituted imidazole derivatives |
| KR20190052007A (ko) | 2016-09-13 | 2019-05-15 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 5-치환된 이미다졸 유도체를 포함하는 활성 화합물 조합물 |
| CN109982999A (zh) * | 2016-09-29 | 2019-07-05 | 拜耳作物科学股份公司 | 新的5-取代的咪唑基甲基衍生物 |
| EP3519390A1 (en) | 2016-09-29 | 2019-08-07 | Bayer CropScience Aktiengesellschaft | 1,5-substituted imidazole derivatives as fungicides for crop protection. |
| BR112019006448A2 (pt) | 2016-09-29 | 2019-06-25 | Bayer Cropscience Ag | novos derivados de 5-imidazol substituídos |
| KR20190054151A (ko) | 2016-09-29 | 2019-05-21 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 살진균제로서의 5-치환된 이미다졸릴메틸옥시란 유도체 |
| MX2019003712A (es) | 2016-09-29 | 2019-06-24 | Bayer Cropscience Ag | Novedosos derivados de imidazolilmetildioxolano 5-sustituidos. |
| EP3519391A1 (en) * | 2016-09-29 | 2019-08-07 | Bayer CropScience Aktiengesellschaft | Novel 5-substituted imidazolylmethyl derivatives |
| WO2018060075A1 (en) | 2016-09-29 | 2018-04-05 | Bayer Cropscience Aktiengesellschaft | 1 -[2-(1 -chlorocyclopropyl)-2-hydroxy-3-(3-phenyl-1,2-oxazol-5-yl)propyl]-1h-imidazole-5-carbonitrile derivatives and related compounds as fungicides for crop protection |
| UY37913A (es) * | 2017-10-05 | 2019-05-31 | Syngenta Participations Ag | Derivados de picolinamida fungicidas que portan un grupo terminal cuaternario |
| WO2019092086A1 (en) | 2017-11-13 | 2019-05-16 | Bayer Aktiengesellschaft | Tetrazolylpropyl derivatives and their use as fungicides |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8304282D0 (en) | 1983-02-16 | 1983-03-23 | Pfizer Ltd | Antifungal agents |
| JPS60172904A (ja) | 1984-02-15 | 1985-09-06 | Shionogi & Co Ltd | 農園芸用殺菌剤 |
| GB8414519D0 (en) * | 1984-06-07 | 1984-07-11 | Pfizer Ltd | Triazole antifungal agents |
| DE3422244A1 (de) * | 1984-06-15 | 1985-12-19 | Bayer Ag, 5090 Leverkusen | 1-azolyl-2-phenyl-cyclopropan-derivate |
| CN1008735B (zh) | 1984-11-02 | 1990-07-11 | 拜尔公司 | 以取代的氮杂茂基甲基-环丙基-甲醇衍生物为活性成分的组合物 |
| DE3440114A1 (de) * | 1984-11-02 | 1986-05-07 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel |
| DE3440117A1 (de) * | 1984-11-02 | 1986-05-15 | Bayer Ag, 5090 Leverkusen | Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate |
| BR8600161A (pt) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio |
| DE3608792A1 (de) * | 1986-03-15 | 1987-09-24 | Hoechst Ag | 1,1-disubstituierte cyclopropanderivate, verfahren zu ihrer herstellung und ihre verwendung |
| ZA874485B (en) * | 1986-06-23 | 1989-02-22 | Du Pont | Antifungal carbinols |
| US5169629A (en) | 1988-11-01 | 1992-12-08 | Mycogen Corporation | Process of controlling lepidopteran pests, using bacillus thuringiensis isolate denoted b.t ps81gg |
| DE3837463A1 (de) * | 1988-11-04 | 1990-05-10 | Bayer Ag | Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA2005658A1 (en) | 1988-12-19 | 1990-06-19 | Eliahu Zlotkin | Insecticidal toxins, genes encoding these toxins, antibodies binding to them and transgenic plant cells and plants expressing these toxins |
| GB8910624D0 (en) | 1989-05-09 | 1989-06-21 | Ici Plc | Bacterial strains |
| CA2015951A1 (en) | 1989-05-18 | 1990-11-18 | Mycogen Corporation | Novel bacillus thuringiensis isolates active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins |
| DE3921162A1 (de) * | 1989-06-28 | 1991-01-10 | Bayer Ag | Verwendung von substituierten bis-azolyl-derivaten zur bekaempfung von pilzen im pflanzenschutz |
| EP0427529B1 (en) | 1989-11-07 | 1995-04-19 | Pioneer Hi-Bred International, Inc. | Larvicidal lectins and plant insect resistance based thereon |
| GB9002375D0 (en) * | 1990-02-02 | 1990-04-04 | Pfizer Ltd | Triazole antifungal agents |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| JP3050982B2 (ja) * | 1991-12-13 | 2000-06-12 | 富山化学工業株式会社 | 新規なトリアゾール誘導体およびその塩 |
| JPH06340636A (ja) * | 1993-05-31 | 1994-12-13 | Ss Pharmaceut Co Ltd | トリアゾール誘導体又はその塩、及びこれを含有する抗真菌剤 |
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| US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
| MX9702382A (es) * | 1995-08-02 | 1998-02-28 | Uriach & Cia Sa J | Nuevos derivados de pirimidona con actividad antifungica. |
| IL125589A0 (en) | 1996-03-11 | 1999-03-12 | Novartis Ag | Pyrimidin-4-one derivatives as pesticides |
| KR100581163B1 (ko) | 2000-08-25 | 2006-05-22 | 신젠타 파티서페이션즈 아게 | 하이브리드 바실러스 튜린지엔시스 독소, 이를 암호화하는 핵산 및 이를 사용한 해충의 방제방법 |
| US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
| AU2002361696A1 (en) | 2001-12-17 | 2003-06-30 | Syngenta Participations Ag | Novel corn event |
| DE102005007160A1 (de) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen |
| ATE489372T1 (de) | 2005-10-25 | 2010-12-15 | Syngenta Participations Ag | Als mikrobiozide geeignete heterocyclische amidderivate |
| WO2008013622A2 (en) | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| US20080032994A1 (en) * | 2006-08-03 | 2008-02-07 | Marcel Borgers | Modified azole compounds as antifungal and antibacterial agents |
| JP5046635B2 (ja) * | 2006-12-22 | 2012-10-10 | 日本エンバイロケミカルズ株式会社 | 木材保存剤 |
| CL2008001647A1 (es) | 2007-06-08 | 2008-10-10 | Syngenta Participations Ag | Compuestos derivados de feniletil-amida de acido-1h-pirazol-4-carboxilico; compuestos derivados de (feniletil)amina; metodo para controlar o prevenir la infestacion de plantas por parte de microorganismos fitopatogenos; y composicion para el control |
| TWI508962B (zh) | 2009-04-22 | 2015-11-21 | Du Pont | 氮雜環醯胺之固體形態 |
| WO2011051243A1 (en) | 2009-10-29 | 2011-05-05 | Bayer Cropscience Ag | Active compound combinations |
| SI2563771T1 (sl) * | 2010-04-24 | 2016-05-31 | Viamet Pharmaceuticals, Inc. | Spojine inhibitorjev metaloencimov |
| KR20140040235A (ko) * | 2011-06-19 | 2014-04-02 | 비아멧 파마슈티컬즈, 인코포레이티드 | 금속효소 억제제 화합물 |
| JP2014523880A (ja) * | 2011-06-23 | 2014-09-18 | ヴィアメット ファーマスーティカルズ，インコーポレイテッド | 金属酵素化合物 |
| EP2766352B1 (en) | 2011-10-12 | 2018-06-06 | University Health Network (UHN) | Indazole compounds as kinase inhibitors and method of treating cancer with same |
-
2014
- 2014-01-28 BR BR112015018547A patent/BR112015018547A2/pt not_active Application Discontinuation
- 2014-01-28 TW TW103103124A patent/TW201441215A/zh unknown
- 2014-01-28 ES ES14701752.9T patent/ES2621386T3/es active Active
- 2014-01-28 EP EP14701752.9A patent/EP2951167B1/en not_active Not-in-force
- 2014-01-28 JP JP2015555678A patent/JP6404235B2/ja not_active Expired - Fee Related
- 2014-01-28 WO PCT/EP2014/051621 patent/WO2014118170A1/en not_active Ceased
- 2014-01-28 US US14/762,007 patent/US9655363B2/en not_active Expired - Fee Related
- 2014-01-28 CN CN201480019921.0A patent/CN105102443B/zh not_active Expired - Fee Related
- 2014-01-31 UY UY0001035295A patent/UY35295A/es not_active Application Discontinuation
- 2014-02-03 AR ARP140100360A patent/AR095137A1/es unknown
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