JP2016505635A5 - - Google Patents

Info

Publication number

JP2016505635A5

JP2016505635A5 JP2015554209A JP2015554209A JP2016505635A5 JP 2016505635 A5 JP2016505635 A5 JP 2016505635A5 JP 2015554209 A JP2015554209 A JP 2015554209A JP 2015554209 A JP2015554209 A JP 2015554209A JP 2016505635 A5 JP2016505635 A5 JP 2016505635A5

Authority

JP

Japan

Prior art keywords

seq

nos

cell

tcr

antigen

Prior art date

2014-01-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 108091008874 T cell receptors Proteins 0.000 claims 15
• 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 15
• 239000000427 antigen Substances 0.000 claims 13
• 108091007433 antigens Proteins 0.000 claims 13
• 102000036639 antigens Human genes 0.000 claims 13
• 210000004027 cell Anatomy 0.000 claims 12
• 108020004707 nucleic acids Proteins 0.000 claims 8
• 150000007523 nucleic acids Chemical class 0.000 claims 8
• 102000039446 nucleic acids Human genes 0.000 claims 8
• 125000003275 alpha amino acid group Chemical group 0.000 claims 6
• 201000010099 disease Diseases 0.000 claims 6
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
• 210000001744 T-lymphocyte Anatomy 0.000 claims 5
• 239000012634 fragment Substances 0.000 claims 5
• 108010047041 Complementarity Determining Regions Proteins 0.000 claims 3
• 230000028993 immune response Effects 0.000 claims 3
• 230000001613 neoplastic effect Effects 0.000 claims 3
• 102000014150 Interferons Human genes 0.000 claims 2
• 108010050904 Interferons Proteins 0.000 claims 2
• 238000003745 diagnosis Methods 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 230000002068 genetic effect Effects 0.000 claims 2
• 229940079322 interferon Drugs 0.000 claims 2
• 230000003211 malignant effect Effects 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• 230000002062 proliferating effect Effects 0.000 claims 2
• 108090000623 proteins and genes Proteins 0.000 claims 2
• 238000000746 purification Methods 0.000 claims 2
• ICTPRLMOGAKCOZ-HWVMREAWSA-N NCCCC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(O)=O)C(C)C)CC1=CC=C(O)C=C1 Chemical compound NCCCC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(O)=O)C(C)C)CC1=CC=C(O)C=C1 ICTPRLMOGAKCOZ-HWVMREAWSA-N 0.000 claims 1
• 230000003044 adaptive effect Effects 0.000 claims 1
• 238000002659 cell therapy Methods 0.000 claims 1
• 238000009169 immunotherapy Methods 0.000 claims 1
• 210000004698 lymphocyte Anatomy 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 230000009258 tissue cross reactivity Effects 0.000 claims 1