JP2016501250A5 - - Google Patents

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Publication number
JP2016501250A5
JP2016501250A5 JP2015546002A JP2015546002A JP2016501250A5 JP 2016501250 A5 JP2016501250 A5 JP 2016501250A5 JP 2015546002 A JP2015546002 A JP 2015546002A JP 2015546002 A JP2015546002 A JP 2015546002A JP 2016501250 A5 JP2016501250 A5 JP 2016501250A5
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JP
Japan
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methyl
compound
phenyl
alkyl
substituted
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JP2015546002A
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English (en)
Japanese (ja)
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JP2016501250A (ja
JP6279605B2 (ja
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Priority claimed from PCT/EP2013/075594 external-priority patent/WO2014086894A1/en
Publication of JP2016501250A publication Critical patent/JP2016501250A/ja
Publication of JP2016501250A5 publication Critical patent/JP2016501250A5/ja
Application granted granted Critical
Publication of JP6279605B2 publication Critical patent/JP6279605B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015546002A 2012-12-06 2013-12-05 自己免疫疾患および炎症性疾患の処置に使用するためのレチノイド関連オーファン受容体ガンマ（ＲＯＲγ）のモジュレーター Expired - Fee Related JP6279605B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN2012001636 2012-12-06
CNPCT/CN2012/001636 2012-12-06
CN2013000182 2013-02-25
CNPCT/CN2013/000182 2013-02-25
CNPCT/CN2013/000803 2013-07-01
CN2013000803 2013-07-01
PCT/EP2013/075594 WO2014086894A1 (en) 2012-12-06 2013-12-05 Modulators of the retinoid-related orphan receptor gamma (ror-gamma) for use in the treatment of autoimmune and inflammatory diseases

Publications (3)

Publication Number Publication Date
JP2016501250A JP2016501250A (ja) 2016-01-18
JP2016501250A5 true JP2016501250A5 (OSRAM) 2017-01-19
JP6279605B2 JP6279605B2 (ja) 2018-02-14

Family

ID=49709687

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015546002A Expired - Fee Related JP6279605B2 (ja) 2012-12-06 2013-12-05 自己免疫疾患および炎症性疾患の処置に使用するためのレチノイド関連オーファン受容体ガンマ（ＲＯＲγ）のモジュレーター

Country Status (33)

Country Link
US (1) US10005731B2 (OSRAM)
EP (2) EP2928885B1 (OSRAM)
JP (1) JP6279605B2 (OSRAM)
KR (1) KR20150092244A (OSRAM)
CN (1) CN105121430B (OSRAM)
AR (1) AR093818A1 (OSRAM)
AU (1) AU2013354109B2 (OSRAM)
BR (1) BR112015013137B1 (OSRAM)
CA (1) CA2894016C (OSRAM)
CL (1) CL2015001557A1 (OSRAM)
CR (1) CR20150302A (OSRAM)
CY (1) CY1118932T1 (OSRAM)
DK (1) DK2928885T3 (OSRAM)
EA (1) EA026437B1 (OSRAM)
ES (1) ES2626390T3 (OSRAM)
HR (1) HRP20170638T1 (OSRAM)
HU (1) HUE033212T2 (OSRAM)
IL (1) IL239082A0 (OSRAM)
LT (1) LT2928885T (OSRAM)
ME (1) ME02696B (OSRAM)
MX (1) MX2015007180A (OSRAM)
PE (1) PE20151144A1 (OSRAM)
PH (1) PH12015501244A1 (OSRAM)
PL (1) PL2928885T3 (OSRAM)
PT (1) PT2928885T (OSRAM)
RS (1) RS55875B1 (OSRAM)
SG (1) SG11201504200TA (OSRAM)
SI (1) SI2928885T1 (OSRAM)
SM (1) SMT201700281T1 (OSRAM)
TW (1) TW201427959A (OSRAM)
UY (1) UY35174A (OSRAM)
WO (1) WO2014086894A1 (OSRAM)
ZA (1) ZA201503666B (OSRAM)

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WO2015017335A1 (en) * 2013-07-30 2015-02-05 Boehringer Ingelheim International Gmbh Azaindole compounds as modulators of rorc
UA121309C2 (uk) 2014-02-03 2020-05-12 Вітае Фармасьютікалс, Ллс Дигідропіролопіридинові інгібітори ror-гамма
JP6759110B2 (ja) * 2014-05-28 2020-09-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 新規な化合物
CA2950220A1 (en) 2014-05-28 2015-12-03 Glaxosmithkline Intellectual Property Development Limited Novel compounds
CA2953637C (en) * 2014-05-28 2022-11-29 Glaxosmithkline Intellectual Property Development Limited Piperazine derivatives as ror-gamma modulators
CN104292208A (zh) * 2014-09-09 2015-01-21 上海师范大学 7-苯基-6,8-二氧杂螺[3.5]壬烷-2-羧酸及其制备方法
MA40759A (fr) * 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
BR112017007460A2 (pt) 2014-10-14 2017-12-19 Vitae Pharmaceuticals Inc inibidores de di-hidropirrolopiridina de ror-gama
TW201625588A (zh) * 2014-11-05 2016-07-16 第一三共股份有限公司 環狀胺衍生物
US9663515B2 (en) 2014-11-05 2017-05-30 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
US9845308B2 (en) 2014-11-05 2017-12-19 Vitae Pharmaceuticals, Inc. Isoindoline inhibitors of ROR-gamma
WO2016120849A1 (en) * 2015-01-30 2016-08-04 Pfizer Inc. Methoxy-substituted pyrrolopyridine modulators of rorc2 and methods of use thereof
ES2856931T3 (es) 2015-08-05 2021-09-28 Vitae Pharmaceuticals Llc Moduladores de ROR-gamma
MX385332B (es) * 2015-11-20 2025-03-18 Vitae Pharmaceuticals Llc Moduladores de ror-gamma.
TW202220968A (zh) 2016-01-29 2022-06-01 美商維它藥物有限責任公司 ＲＯＲ－γ調節劑
US9481674B1 (en) 2016-06-10 2016-11-01 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
ES2834009T3 (es) 2016-07-13 2021-06-16 Leo Pharma As Moduladores heteroaromáticos del receptor gamma huérfano relacionado con retinoides
CN109134476B (zh) * 2017-06-15 2021-03-19 复旦大学 桥环哌嗪类衍生物或其盐及其制备方法和用途
US11001552B2 (en) 2017-07-18 2021-05-11 Lonza Ltd Method for preparation of 5-fluoro-2-methyl-3-nitrobenzoic acid and its methyl ester
WO2019018975A1 (en) 2017-07-24 2019-01-31 Vitae Pharmaceuticals, Inc. INHIBITORS OF ROR GAMMA
CN111225914B (zh) 2017-07-24 2022-10-11 生命医药有限责任公司 RORγ的抑制剂
CN108752185A (zh) * 2018-07-17 2018-11-06 成都道合尔医药技术有限公司 一种1-氟-环戊甲酸的合成方法
CN109438423A (zh) * 2018-09-12 2019-03-08 通化师范学院 一种肺癌靶向化合物azd-3759的合成工艺的新方法
CN110862319A (zh) * 2019-12-04 2020-03-06 深圳振强生物技术有限公司 奥扎格雷杂质的制备方法
WO2023232870A1 (en) 2022-05-31 2023-12-07 Immunic Ag Rorg/rorgt modulators for the treatment of virus infections like covid-19

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US7790726B2 (en) 2005-08-16 2010-09-07 Chemocentryx, Inc. Monocyclic and bicyclic compounds and methods of use
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WO2012027965A1 (en) 2010-09-01 2012-03-08 Glaxo Group Limited Novel compounds
WO2012028100A1 (en) 2010-09-01 2012-03-08 Glaxo Group Limited Novel compounds
WO2012100734A1 (en) 2011-01-24 2012-08-02 Glaxo Group Limited Compounds useful as retinoid-related orphan receptor gamma modulators
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WO2012145254A2 (en) 2011-04-16 2012-10-26 Board Of Regents, The University Of Texas System Methods of using inhibitors of rorϒt to treat disease
TWI532728B (zh) * 2011-04-28 2016-05-11 日本煙草產業股份有限公司 醯胺化合物及其醫藥用途
US9586928B2 (en) * 2011-05-16 2017-03-07 The Scripps Research Institute Modulators of the nuclear hormone receptor ROR
JP2014528933A (ja) 2011-09-09 2014-10-30 ニューヨーク ユニバーシティ ＲＯＲγｔモジュレーターとしてのアミド化合物およびその使用
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
TWI593678B (zh) 2012-04-27 2017-08-01 葛蘭素集團有限公司 作為類視色素相關孤兒受體γ(RORγ)調節劑之化合物、其醫藥組合物及用途
WO2013171729A2 (en) 2013-01-08 2013-11-21 Glenmark Pharmaceuticals S.A. Aryl and heteroaryl amide compounds as rorgamat modulator
US10286000B2 (en) 2013-10-25 2019-05-14 St. Jude Children's Research Hospital, Inc. Retinoid X receptor-gamma agonists and retinoid X receptor-alpha antagonists for treatment of cancer
CA2928537A1 (en) 2013-10-25 2015-04-30 Glaxosmithkline Llc Novel compounds
CA2950220A1 (en) 2014-05-28 2015-12-03 Glaxosmithkline Intellectual Property Development Limited Novel compounds
JP6759110B2 (ja) 2014-05-28 2020-09-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 新規な化合物
CA2953637C (en) 2014-05-28 2022-11-29 Glaxosmithkline Intellectual Property Development Limited Piperazine derivatives as ror-gamma modulators

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