JP2016065095A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016065095A5 JP2016065095A5 JP2015238594A JP2015238594A JP2016065095A5 JP 2016065095 A5 JP2016065095 A5 JP 2016065095A5 JP 2015238594 A JP2015238594 A JP 2015238594A JP 2015238594 A JP2015238594 A JP 2015238594A JP 2016065095 A5 JP2016065095 A5 JP 2016065095A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous solution
- ophthalmic aqueous
- polyethylene
- solution according
- ophthalmic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 polyethylene Polymers 0.000 claims 31
- 239000007864 aqueous solution Substances 0.000 claims 22
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 10
- 239000004698 Polyethylene Substances 0.000 claims 10
- 239000000463 material Substances 0.000 claims 10
- 229920000573 polyethylene Polymers 0.000 claims 10
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 9
- 239000011347 resin Substances 0.000 claims 8
- 229920005989 resin Polymers 0.000 claims 8
- WSNODXPBBALQOF-VEJSHDCNSA-N tafluprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1 WSNODXPBBALQOF-VEJSHDCNSA-N 0.000 claims 8
- 229960004458 tafluprost Drugs 0.000 claims 8
- 239000003381 stabilizer Substances 0.000 claims 7
- 239000002736 nonionic surfactant Substances 0.000 claims 6
- 239000004359 castor oil Substances 0.000 claims 5
- 235000019438 castor oil Nutrition 0.000 claims 5
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 5
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 5
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 5
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 5
- 229940068968 polysorbate 80 Drugs 0.000 claims 5
- 229920000053 polysorbate 80 Polymers 0.000 claims 5
- 239000003755 preservative agent Substances 0.000 claims 5
- 230000002335 preservative effect Effects 0.000 claims 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 4
- 239000012611 container material Substances 0.000 claims 4
- 239000002552 dosage form Substances 0.000 claims 4
- 125000006353 oxyethylene group Chemical group 0.000 claims 4
- 229920001451 polypropylene glycol Polymers 0.000 claims 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 229940054534 ophthalmic solution Drugs 0.000 claims 3
- 239000002997 ophthalmic solution Substances 0.000 claims 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 2
- 229920000178 Acrylic resin Polymers 0.000 claims 2
- 239000004925 Acrylic resin Substances 0.000 claims 2
- 229920002292 Nylon 6 Polymers 0.000 claims 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 239000004793 Polystyrene Substances 0.000 claims 2
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims 2
- 229940124274 edetate disodium Drugs 0.000 claims 2
- 238000010101 extrusion blow moulding Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000003002 pH adjusting agent Substances 0.000 claims 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims 2
- 229920000139 polyethylene terephthalate Polymers 0.000 claims 2
- 239000005020 polyethylene terephthalate Substances 0.000 claims 2
- 239000004926 polymethyl methacrylate Substances 0.000 claims 2
- 229920001155 polypropylene Polymers 0.000 claims 2
- 229920002223 polystyrene Polymers 0.000 claims 2
- 239000004800 polyvinyl chloride Substances 0.000 claims 2
- 229920000915 polyvinyl chloride Polymers 0.000 claims 2
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 claims 2
- QIJRTFXNRTXDIP-UHFFFAOYSA-N (1-carboxy-2-sulfanylethyl)azanium;chloride;hydrate Chemical compound O.Cl.SCC(N)C(O)=O QIJRTFXNRTXDIP-UHFFFAOYSA-N 0.000 claims 1
- CSTRPYAGFNTOEQ-MGMRMFRLSA-N (2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;octadecanoic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O.CCCCCCCCCCCCCCCCCC(O)=O CSTRPYAGFNTOEQ-MGMRMFRLSA-N 0.000 claims 1
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims 1
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 claims 1
- 229940058015 1,3-butylene glycol Drugs 0.000 claims 1
- YHMYGUUIMTVXNW-UHFFFAOYSA-N 1,3-dihydrobenzimidazole-2-thione Chemical compound C1=CC=C2NC(S)=NC2=C1 YHMYGUUIMTVXNW-UHFFFAOYSA-N 0.000 claims 1
- OOSZCNKVJAVHJI-UHFFFAOYSA-N 1-[(4-fluorophenyl)methyl]piperazine Chemical compound C1=CC(F)=CC=C1CN1CCNCC1 OOSZCNKVJAVHJI-UHFFFAOYSA-N 0.000 claims 1
- PZNPLUBHRSSFHT-RRHRGVEJSA-N 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCC PZNPLUBHRSSFHT-RRHRGVEJSA-N 0.000 claims 1
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 claims 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims 1
- ICSFDFVNBLXDRZ-UHFFFAOYSA-N C(Cl)Cl.[K] Chemical compound C(Cl)Cl.[K] ICSFDFVNBLXDRZ-UHFFFAOYSA-N 0.000 claims 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims 1
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-araboascorbic acid Natural products OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 206010030043 Ocular hypertension Diseases 0.000 claims 1
- YYVFXSYQSOZCOQ-UHFFFAOYSA-N Oxyquinoline sulfate Chemical compound [O-]S([O-])(=O)=O.C1=C[NH+]=C2C(O)=CC=CC2=C1.C1=C[NH+]=C2C(O)=CC=CC2=C1 YYVFXSYQSOZCOQ-UHFFFAOYSA-N 0.000 claims 1
- 229920002415 Pluronic P-123 Polymers 0.000 claims 1
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims 1
- 229920001219 Polysorbate 40 Polymers 0.000 claims 1
- 229920001214 Polysorbate 60 Polymers 0.000 claims 1
- 229920002642 Polysorbate 65 Polymers 0.000 claims 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 claims 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 claims 1
- IYFATESGLOUGBX-YVNJGZBMSA-N Sorbitan monopalmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O IYFATESGLOUGBX-YVNJGZBMSA-N 0.000 claims 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims 1
- 239000004147 Sorbitan trioleate Substances 0.000 claims 1
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- IJCWFDPJFXGQBN-RYNSOKOISA-N [(2R)-2-[(2R,3R,4S)-4-hydroxy-3-octadecanoyloxyoxolan-2-yl]-2-octadecanoyloxyethyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCCCCCCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCCCCCCCCCCCC IJCWFDPJFXGQBN-RYNSOKOISA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 125000003289 ascorbyl group Chemical group [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 claims 1
- 235000019437 butane-1,3-diol Nutrition 0.000 claims 1
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims 1
- 229960004106 citric acid Drugs 0.000 claims 1
- 229960001305 cysteine hydrochloride Drugs 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- VZFDRQUWHOVFCA-UHFFFAOYSA-L disodium;2-sulfanylbutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(S)C([O-])=O VZFDRQUWHOVFCA-UHFFFAOYSA-L 0.000 claims 1
- 229960001484 edetic acid Drugs 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 235000010350 erythorbic acid Nutrition 0.000 claims 1
- 239000004318 erythorbic acid Substances 0.000 claims 1
- HQPMKSGTIOYHJT-UHFFFAOYSA-N ethane-1,2-diol;propane-1,2-diol Chemical compound OCCO.CC(O)CO HQPMKSGTIOYHJT-UHFFFAOYSA-N 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 229940026239 isoascorbic acid Drugs 0.000 claims 1
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 claims 1
- 239000007951 isotonicity adjuster Substances 0.000 claims 1
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 claims 1
- 229960001257 oxyquinoline sulfate Drugs 0.000 claims 1
- DOIRQSBPFJWKBE-UHFFFAOYSA-N phthalic acid di-n-butyl ester Natural products CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 claims 1
- 229920001993 poloxamer 188 Polymers 0.000 claims 1
- 229920001992 poloxamer 407 Polymers 0.000 claims 1
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 claims 1
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 claims 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims 1
- 239000001816 polyoxyethylene sorbitan tristearate Substances 0.000 claims 1
- 235000010988 polyoxyethylene sorbitan tristearate Nutrition 0.000 claims 1
- 229940099429 polyoxyl 40 stearate Drugs 0.000 claims 1
- 229940101027 polysorbate 40 Drugs 0.000 claims 1
- 229940113124 polysorbate 60 Drugs 0.000 claims 1
- 229940099511 polysorbate 65 Drugs 0.000 claims 1
- 239000000473 propyl gallate Substances 0.000 claims 1
- 235000010388 propyl gallate Nutrition 0.000 claims 1
- 229940075579 propyl gallate Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 235000002639 sodium chloride Nutrition 0.000 claims 1
- 229940074545 sodium dihydrogen phosphate dihydrate Drugs 0.000 claims 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 claims 1
- 235000010262 sodium metabisulphite Nutrition 0.000 claims 1
- 235000010288 sodium nitrite Nutrition 0.000 claims 1
- 229960000819 sodium nitrite Drugs 0.000 claims 1
- GNBVPFITFYNRCN-UHFFFAOYSA-M sodium thioglycolate Chemical compound [Na+].[O-]C(=O)CS GNBVPFITFYNRCN-UHFFFAOYSA-M 0.000 claims 1
- 229940046307 sodium thioglycolate Drugs 0.000 claims 1
- 229940035044 sorbitan monolaurate Drugs 0.000 claims 1
- 239000001593 sorbitan monooleate Substances 0.000 claims 1
- 235000011069 sorbitan monooleate Nutrition 0.000 claims 1
- 229940035049 sorbitan monooleate Drugs 0.000 claims 1
- 239000001570 sorbitan monopalmitate Substances 0.000 claims 1
- 235000011071 sorbitan monopalmitate Nutrition 0.000 claims 1
- 229940031953 sorbitan monopalmitate Drugs 0.000 claims 1
- 239000001587 sorbitan monostearate Substances 0.000 claims 1
- 235000011076 sorbitan monostearate Nutrition 0.000 claims 1
- 229940035048 sorbitan monostearate Drugs 0.000 claims 1
- 235000019337 sorbitan trioleate Nutrition 0.000 claims 1
- 229960000391 sorbitan trioleate Drugs 0.000 claims 1
- 239000001589 sorbitan tristearate Substances 0.000 claims 1
- 235000011078 sorbitan tristearate Nutrition 0.000 claims 1
- 229960004129 sorbitan tristearate Drugs 0.000 claims 1
- 239000008347 soybean phospholipid Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 229960004605 timolol Drugs 0.000 claims 1
- 235000010384 tocopherol Nutrition 0.000 claims 1
- 229930003799 tocopherol Natural products 0.000 claims 1
- 229960001295 tocopherol Drugs 0.000 claims 1
- 239000011732 tocopherol Substances 0.000 claims 1
- 229940042585 tocopherol acetate Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08397513A EP2127638A1 (en) | 2008-05-30 | 2008-05-30 | Method and composition for treating ocular hypertension and glaucoma |
| EP08397513.6 | 2008-05-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014088256A Division JP2014133765A (ja) | 2008-05-30 | 2014-04-22 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017098843A Division JP6356868B2 (ja) | 2008-05-30 | 2017-05-18 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016065095A JP2016065095A (ja) | 2016-04-28 |
| JP2016065095A5 true JP2016065095A5 (enExample) | 2016-07-14 |
| JP6148317B2 JP6148317B2 (ja) | 2017-06-14 |
Family
ID=39940592
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011511256A Pending JP2011521943A (ja) | 2008-05-30 | 2009-05-28 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2014088256A Pending JP2014133765A (ja) | 2008-05-30 | 2014-04-22 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2015238594A Active JP6148317B2 (ja) | 2008-05-30 | 2015-12-07 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2017098843A Active JP6356868B2 (ja) | 2008-05-30 | 2017-05-18 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2018113647A Active JP6649992B2 (ja) | 2008-05-30 | 2018-06-14 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2020005799A Active JP6889789B2 (ja) | 2008-05-30 | 2020-01-17 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2021085839A Active JP7265584B2 (ja) | 2008-05-30 | 2021-05-21 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2023066348A Active JP7520285B2 (ja) | 2008-05-30 | 2023-04-14 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2024064531A Pending JP2024079852A (ja) | 2008-05-30 | 2024-04-12 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011511256A Pending JP2011521943A (ja) | 2008-05-30 | 2009-05-28 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2014088256A Pending JP2014133765A (ja) | 2008-05-30 | 2014-04-22 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017098843A Active JP6356868B2 (ja) | 2008-05-30 | 2017-05-18 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2018113647A Active JP6649992B2 (ja) | 2008-05-30 | 2018-06-14 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2020005799A Active JP6889789B2 (ja) | 2008-05-30 | 2020-01-17 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2021085839A Active JP7265584B2 (ja) | 2008-05-30 | 2021-05-21 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2023066348A Active JP7520285B2 (ja) | 2008-05-30 | 2023-04-14 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
| JP2024064531A Pending JP2024079852A (ja) | 2008-05-30 | 2024-04-12 | 高眼圧症及び緑内障を治療するための方法及び組成物 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US9999593B2 (enExample) |
| EP (8) | EP2127638A1 (enExample) |
| JP (9) | JP2011521943A (enExample) |
| KR (5) | KR102246598B1 (enExample) |
| CN (1) | CN102083413B (enExample) |
| AR (2) | AR071937A1 (enExample) |
| AU (1) | AU2009252210C1 (enExample) |
| BR (1) | BRPI0913109B8 (enExample) |
| CA (2) | CA2724194C (enExample) |
| CY (2) | CY1115565T1 (enExample) |
| DK (4) | DK2772249T3 (enExample) |
| EA (1) | EA023661B1 (enExample) |
| ES (7) | ES2495316T3 (enExample) |
| GE (1) | GEP20156220B (enExample) |
| HR (4) | HRP20220361T1 (enExample) |
| HU (3) | HUE049923T2 (enExample) |
| JO (1) | JO3039B1 (enExample) |
| LT (3) | LT3205334T (enExample) |
| MX (1) | MX2010012987A (enExample) |
| MY (1) | MY159463A (enExample) |
| PL (4) | PL3205334T3 (enExample) |
| PT (4) | PT3714877T (enExample) |
| SG (1) | SG191628A1 (enExample) |
| SI (4) | SI2772249T1 (enExample) |
| TW (1) | TWI432202B (enExample) |
| UA (1) | UA102257C2 (enExample) |
| WO (1) | WO2009145356A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
| EP2389939A1 (en) | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
| US20110136872A1 (en) * | 2009-12-09 | 2011-06-09 | Burk Robert M | Stable aqueous compositions of prostglandin agonist prodrugs and methods for use thereof |
| JP5681472B2 (ja) * | 2009-12-28 | 2015-03-11 | ロート製薬株式会社 | 眼科用組成物 |
| FR2961694B1 (fr) * | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
| US10154923B2 (en) * | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
| US9061034B2 (en) * | 2010-07-29 | 2015-06-23 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
| AU2011282679A1 (en) * | 2010-07-29 | 2013-03-07 | Allergan, Inc. | Preservative free bimatoprost solutions |
| HUE059325T2 (hu) * | 2010-07-29 | 2022-11-28 | Allergan Inc | Tartósítószer-mentes bimatoprost és timolol oldatok |
| WO2012021107A2 (en) | 2010-08-12 | 2012-02-16 | Nanyang Technological University | A liposomal formulation for ocular drug delivery |
| ES2616089T3 (es) * | 2010-09-21 | 2017-06-09 | S & V Technologies Gmbh | Composición cosmética |
| EP2452669A1 (en) * | 2010-10-29 | 2012-05-16 | Omnivision GmbH | Ophthalmic composition |
| CN103596572A (zh) * | 2011-04-12 | 2014-02-19 | 株式会社·R-技术上野 | 水性眼用组合物 |
| CN102716074B (zh) * | 2012-06-28 | 2013-10-16 | 武汉武药科技有限公司 | 一种贝美前列素滴眼剂及其制备方法 |
| PL2887923T3 (pl) | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
| WO2015106068A1 (en) | 2014-01-10 | 2015-07-16 | Manistee Partners Llc | Treatment of migraines |
| CN104766952B (zh) * | 2015-04-21 | 2017-01-25 | 武汉凯迪工程技术研究总院有限公司 | 利用生物质气化炉滤渣制备锂离子电池负极材料的方法 |
| ES2747302T3 (es) | 2015-06-09 | 2020-03-10 | Medproject Pharma Entw Und Vertriebsgesellschaft Mbh | Gel oftálmico de bimatoprost aplicable en gotas |
| US10105371B2 (en) * | 2015-10-09 | 2018-10-23 | Tamara Vrabec | Use of medications with neuroprotective properties to prevent or reduce the risk of ischemia-reperfusion injury in a subject |
| EP3370709A4 (en) * | 2015-11-06 | 2019-12-18 | Accuitis Pharmaceuticals, Inc. | USE OF PROTEASOME INHIBITORS FOR THE TREATMENT OF EYE DISEASES |
| DK3373976T3 (da) | 2015-11-10 | 2024-04-02 | Sun Pharmaceutical Ind Ltd | Topiske formuleringer og anvendelser deraf |
| NZ785158A (en) | 2016-02-29 | 2025-03-28 | Sun Pharmaceutical Ind Ltd | Topical cyclosporine-containing formulations and uses thereof |
| GR1009040B (el) * | 2016-04-19 | 2017-05-19 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο οφθαλμικο σκευασμα ελευθερο συντηρητικου |
| WO2018033854A1 (en) * | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
| KR101770324B1 (ko) * | 2016-11-09 | 2017-08-22 | 주식회사태준제약 | 안압 강하용 점안 조성물 |
| JP2020059652A (ja) * | 2016-12-26 | 2020-04-16 | 参天製薬株式会社 | タフルプロストとクエン酸エステルとを含有するデポ剤 |
| EP3603642B1 (en) * | 2017-03-27 | 2024-01-10 | Alcon Inc. | Pharmaceutical preparation |
| US20180318319A1 (en) * | 2017-05-04 | 2018-11-08 | Ocular Science, Inc. | Compositions and Methods for Treating Eyes and Methods of Preparation |
| WO2018236158A1 (ko) | 2017-06-22 | 2018-12-27 | 연성정밀화학(주) | 녹내장 치료용 점안 조성물 |
| EP3730138B1 (en) * | 2017-12-21 | 2024-02-14 | Santen Pharmaceutical Co., Ltd. | Combination of sepetaprost and ripasudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension |
| US12263119B2 (en) | 2018-07-09 | 2025-04-01 | Zaklady Farmaceutyczne Polpharma S.A. | Opthalmic dispensing device |
| JP7599838B2 (ja) * | 2019-04-10 | 2024-12-16 | 参天製薬株式会社 | エピナスチン又はその塩を含有する水性医薬組成物 |
| CN111632025A (zh) * | 2020-03-04 | 2020-09-08 | 吉林大学第一医院 | 一种贝美前列素眼用温度敏感型原位凝胶及其制备方法与应用 |
| CN111840225B (zh) * | 2020-08-12 | 2021-09-14 | 陈丽娜 | 一种用于治疗青光眼的滴眼剂及其制备方法 |
| RU2761625C2 (ru) * | 2021-02-11 | 2021-12-13 | Общество с ограниченной ответственностью "Гротекс" (ООО "Гротекс") | Фармацевтическая композиция тафлупроста |
| CN116687842A (zh) * | 2022-02-28 | 2023-09-05 | 山东新时代药业有限公司 | 一种拉坦前列素滴眼液及其制备方法 |
| AU2023240729A1 (en) * | 2022-03-25 | 2024-10-03 | Tsubota Laboratory, Inc. | Aqueous composition |
| WO2023241652A1 (zh) * | 2022-06-16 | 2023-12-21 | 广州润尔眼科生物科技有限公司 | 一种药物组合物及其制备方法和应用 |
| WO2024203727A1 (ja) * | 2023-03-24 | 2024-10-03 | 株式会社坪田ラボ | 水性組成物 |
| WO2024232425A1 (ja) * | 2023-05-11 | 2024-11-14 | テイカ製薬株式会社 | プロスタグランジンＦ２α誘導体の含有率低下が抑制されている製品 |
| JP7757564B1 (ja) | 2024-06-28 | 2025-10-21 | 東亜薬品株式会社 | 水性組成物 |
| GR1011143B (el) * | 2025-04-11 | 2026-03-02 | Ιουλια Τσετη | Οφθαλμικο διαλυμα προσταγλανδινης χωρις συντηρητικα |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4778815A (en) * | 1987-03-18 | 1988-10-18 | Ciba-Geigy Corporation | Method of inhibiting cataracts by topical application of a 2-substituted 1,2-benzisoselenazol-3(2H)-one |
| ATE76750T1 (de) | 1987-04-03 | 1992-06-15 | Univ Columbia | Anwendung eines prostaglandins in mischung mit einem adrenergischen blocker zur verminderung des augen-innendruckes. |
| US5409125A (en) | 1989-12-11 | 1995-04-25 | Aktiebolaget Astra | Unit dose container |
| DE4027320C2 (de) | 1990-08-29 | 1993-09-30 | Ursapharm Arzneimittel Gmbh | Fluid-Abgabeeinrichtung für keimfreies Fluid |
| JPH0655640A (ja) | 1992-08-04 | 1994-03-01 | Aavan Internatl:Kk | 洗面台カウンター及びその製造方法 |
| JPH06107547A (ja) | 1992-10-01 | 1994-04-19 | Aarutetsuku Ueno:Kk | 眼科用組成物 |
| AU665287B2 (en) | 1992-12-21 | 1995-12-21 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| JP2510066Y2 (ja) | 1993-01-20 | 1996-09-11 | 東洋製罐株式会社 | 加熱殺菌可能な液体医薬容器 |
| US5807892A (en) | 1994-09-30 | 1998-09-15 | Alcon Laboratories, Inc. | Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension |
| US5631287A (en) | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| CA2237898A1 (en) * | 1995-11-17 | 1997-05-29 | Louis Desantis Jr. | Combination therapy for treating glaucoma |
| EP0930296B2 (en) | 1996-09-17 | 2005-11-02 | Asahi Glass Company Ltd. | Fluorinated prostaglandin derivatives and medicines |
| CA2273837C (en) | 1996-12-09 | 2003-12-30 | Bausch & Lomb Incorporated | Single-use flexible container |
| JP3480549B2 (ja) | 1996-12-26 | 2003-12-22 | 参天製薬株式会社 | ジフルオロプロスタグランジン誘導体およびその用途 |
| AR002194A1 (es) | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| CA2274708A1 (en) * | 1997-10-13 | 1999-04-22 | R-Tech Ueno, Ltd. | Remedial composition for intraocular hypertension or glaucoma |
| US6066671A (en) | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
| GB2337740B (en) | 1998-05-26 | 2000-11-15 | Spreckelsen Mcgeough Ltd | Fluid packaging |
| US6235781B1 (en) | 1998-07-14 | 2001-05-22 | Alcon Laboratories, Inc. | Prostaglandin product |
| CA2295512C (en) | 1998-07-14 | 2009-05-26 | Alcon Laboratories, Inc. | Prostaglandin product |
| WO2000018316A2 (en) | 1998-09-25 | 2000-04-06 | Alcon Laboratories, Inc. | Sustained release, and comfortable ophthalmic composition and method for ocular therapy |
| US6096783A (en) | 1998-12-15 | 2000-08-01 | Alcon Laboratories, Inc. | Cyclobutane prostaglandin analogues as ocular hypotensive agents |
| AU2183900A (en) | 1998-12-24 | 2000-07-31 | Alcon Laboratories, Inc. | Ep4 receptor agonists for treatment of dry eye |
| CA2368083A1 (en) | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Derivatives of venlafaxine and methods of preparing and using the same |
| EP1312380B1 (en) | 2000-06-19 | 2006-05-03 | Santen Pharmaceutical Co., Ltd. | Aseptics |
| JP3876355B2 (ja) | 2000-09-13 | 2007-01-31 | 参天製薬株式会社 | 点眼液 |
| PT1321144E (pt) | 2000-09-13 | 2011-03-10 | Santen Pharmaceutical Co Ltd | Colírio |
| TW586946B (en) | 2000-12-22 | 2004-05-11 | Novartis Ag | Process to improve stability |
| WO2004006826A1 (ja) | 2002-07-16 | 2004-01-22 | Senju Pharmaceutical Co., Ltd. | 薬液容器及びその製造方法 |
| CA2498233C (en) | 2002-09-09 | 2012-08-14 | Santen Pharmaceutical Co., Ltd. | Clear ophthalmic solution comprising latanoprost as active ingredient |
| US7074827B2 (en) * | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
| US20060199863A1 (en) * | 2003-07-31 | 2006-09-07 | Santen Pharmaceutical Co., Ltd. | Product containing prostaglandin |
| US20050287325A1 (en) | 2004-06-25 | 2005-12-29 | Pharmacia & Upjohn Company | Pharmaceutical containers with low adsorption/absorption of active ingredients, and a method of testing materials for adsorption/absorption of active ingredients |
| EP1655021B1 (en) * | 2004-11-09 | 2008-10-29 | Novagali Pharma SA | Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential |
| US7562796B2 (en) | 2004-11-24 | 2009-07-21 | Holopack International Corp. | Dispensing container with flow control system |
| CA2590277C (en) | 2004-12-09 | 2014-07-08 | Santen Pharmaceutical Co., Ltd. | Product containing prostaglandin having fluorine atom in its molecule |
| DK1829545T3 (da) | 2004-12-24 | 2012-07-23 | Santen Pharmaceutical Co Ltd | Produkter indeholdende prostaglandin-F2alfa-derivat |
| GB0501192D0 (en) * | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
| PT1905453E (pt) * | 2005-07-13 | 2012-12-04 | Santen Pharmaceutical Co Ltd | Composição conservante para utilização oftálmica |
| US8030349B2 (en) * | 2005-08-02 | 2011-10-04 | Santen Pharmaceutical Co., Ltd. | Method for prevention of degradation of thermally unstable medicament |
| CN101282714B (zh) | 2005-10-10 | 2012-12-12 | 诺瓦加利制药公司 | 包含前列腺素的眼用乳剂 |
| FI126233B (sv) | 2006-02-23 | 2016-08-31 | Oy Kwh Mirka Ab | Oscillerande slipmaskin |
| FR2918891B1 (fr) | 2007-07-20 | 2009-09-25 | Thea Sa Lab | Solution ophtalmique a base de prostaglandines sans conservateur |
| KR100927617B1 (ko) | 2007-11-26 | 2009-11-23 | 한국표준과학연구원 | 열분해 탄소 성분의 나노 크기를 가지는 바이오 센서의감지부를 제작하는 방법 |
| EP2127638A1 (en) * | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
-
2008
- 2008-05-30 EP EP08397513A patent/EP2127638A1/en not_active Withdrawn
-
2009
- 2009-05-19 TW TW098116503A patent/TWI432202B/zh active
- 2009-05-27 JO JOP/2009/0192A patent/JO3039B1/ar active
- 2009-05-28 AU AU2009252210A patent/AU2009252210C1/en not_active Ceased
- 2009-05-28 SI SI200931694T patent/SI2772249T1/sl unknown
- 2009-05-28 PT PT201646023T patent/PT3714877T/pt unknown
- 2009-05-28 PT PT170004402T patent/PT3205334T/pt unknown
- 2009-05-28 EP EP21217057.5A patent/EP4035656B1/en active Active
- 2009-05-28 SI SI200932073T patent/SI3205334T1/sl unknown
- 2009-05-28 DK DK14001862.3T patent/DK2772249T3/en active
- 2009-05-28 UA UAA201015619A patent/UA102257C2/uk unknown
- 2009-05-28 PT PT97548648T patent/PT2306977E/pt unknown
- 2009-05-28 LT LTEP17000440.2T patent/LT3205334T/lt unknown
- 2009-05-28 ES ES09754864.8T patent/ES2495316T3/es active Active
- 2009-05-28 PL PL17000440T patent/PL3205334T3/pl unknown
- 2009-05-28 HU HUE17000440A patent/HUE049923T2/hu unknown
- 2009-05-28 EA EA201071413A patent/EA023661B1/ru unknown
- 2009-05-28 LT LTEP20164602.3T patent/LT3714877T/lt unknown
- 2009-05-28 KR KR1020207014211A patent/KR102246598B1/ko active Active
- 2009-05-28 PT PT140018623T patent/PT2772249T/pt unknown
- 2009-05-28 DK DK20164602.3T patent/DK3714877T3/da active
- 2009-05-28 ES ES21217057T patent/ES2968837T3/es active Active
- 2009-05-28 ES ES20164602T patent/ES2907982T3/es active Active
- 2009-05-28 EP EP17000440.2A patent/EP3205334B1/en not_active Revoked
- 2009-05-28 SG SG2013041751A patent/SG191628A1/en unknown
- 2009-05-28 HU HUE14001862A patent/HUE033103T2/en unknown
- 2009-05-28 KR KR1020107029072A patent/KR101650006B1/ko active Active
- 2009-05-28 CA CA2724194A patent/CA2724194C/en active Active
- 2009-05-28 ES ES14001862.3T patent/ES2627837T3/es active Active
- 2009-05-28 PL PL14001862T patent/PL2772249T3/pl unknown
- 2009-05-28 US US12/995,351 patent/US9999593B2/en active Active
- 2009-05-28 PL PL20164602T patent/PL3714877T3/pl unknown
- 2009-05-28 DK DK17000440.2T patent/DK3205334T3/da active
- 2009-05-28 DK DK09754864.8T patent/DK2306977T3/da active
- 2009-05-28 HR HRP20220361TT patent/HRP20220361T1/hr unknown
- 2009-05-28 EP EP25150453.6A patent/EP4512424B1/en active Active
- 2009-05-28 BR BRPI0913109A patent/BRPI0913109B8/pt not_active IP Right Cessation
- 2009-05-28 EP EP20164602.3A patent/EP3714877B1/en not_active Revoked
- 2009-05-28 KR KR1020187001130A patent/KR101988642B1/ko active Active
- 2009-05-28 MX MX2010012987A patent/MX2010012987A/es active IP Right Grant
- 2009-05-28 CA CA2965185A patent/CA2965185A1/en not_active Abandoned
- 2009-05-28 KR KR1020197016340A patent/KR102114401B1/ko active Active
- 2009-05-28 HU HUE20164602A patent/HUE058079T2/hu unknown
- 2009-05-28 GE GEAP200912045A patent/GEP20156220B/en unknown
- 2009-05-28 MY MYPI2010005463A patent/MY159463A/en unknown
- 2009-05-28 KR KR1020167022210A patent/KR101820816B1/ko active Active
- 2009-05-28 EP EP23202597.3A patent/EP4289446B1/en active Active
- 2009-05-28 SI SI200931050T patent/SI2306977T1/sl unknown
- 2009-05-28 ES ES25150453T patent/ES3069010T3/es active Active
- 2009-05-28 AR ARP090101912A patent/AR071937A1/es not_active Application Discontinuation
- 2009-05-28 CN CN2009801197245A patent/CN102083413B/zh active Active
- 2009-05-28 LT LTEP14001862.3T patent/LT2772249T/lt unknown
- 2009-05-28 ES ES23202597T patent/ES3014089T3/es active Active
- 2009-05-28 EP EP14001862.3A patent/EP2772249B1/en not_active Revoked
- 2009-05-28 EP EP09754864.8A patent/EP2306977B1/en active Active
- 2009-05-28 PL PL09754864T patent/PL2306977T3/pl unknown
- 2009-05-28 JP JP2011511256A patent/JP2011521943A/ja active Pending
- 2009-05-28 WO PCT/JP2009/060211 patent/WO2009145356A1/en not_active Ceased
- 2009-05-28 SI SI200932159T patent/SI3714877T1/sl unknown
- 2009-05-28 HR HRP20140979AT patent/HRP20140979T1/hr unknown
- 2009-05-28 ES ES17000440T patent/ES2808050T3/es active Active
-
2014
- 2014-04-22 JP JP2014088256A patent/JP2014133765A/ja active Pending
- 2014-09-18 CY CY20141100763T patent/CY1115565T1/el unknown
-
2015
- 2015-12-07 JP JP2015238594A patent/JP6148317B2/ja active Active
-
2017
- 2017-05-18 JP JP2017098843A patent/JP6356868B2/ja active Active
- 2017-05-23 HR HRP20170769TT patent/HRP20170769T1/hr unknown
- 2017-06-27 CY CY20171100675T patent/CY1120351T1/el unknown
-
2018
- 2018-06-14 JP JP2018113647A patent/JP6649992B2/ja active Active
- 2018-06-18 US US16/010,739 patent/US10864159B2/en active Active
- 2018-11-01 AR ARP180103181A patent/AR120961A2/es not_active Application Discontinuation
-
2020
- 2020-01-17 JP JP2020005799A patent/JP6889789B2/ja active Active
- 2020-06-24 HR HRP20200998TT patent/HRP20200998T1/hr unknown
- 2020-11-11 US US17/094,986 patent/US20210059931A1/en not_active Abandoned
-
2021
- 2021-05-21 JP JP2021085839A patent/JP7265584B2/ja active Active
-
2023
- 2023-04-14 JP JP2023066348A patent/JP7520285B2/ja active Active
-
2024
- 2024-04-12 JP JP2024064531A patent/JP2024079852A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20140979T1 (hr) | Postupak i sastav za lijeäśenje okularne hipertenzije i glaukoma | |
| ES2357551T3 (es) | Colirio. | |
| JP3876355B2 (ja) | 点眼液 | |
| JP6449205B2 (ja) | ピリジルアミノ酢酸化合物とポリオキシエチレンヒマシ油含有医薬組成物 | |
| RU2010139958A (ru) | Стабилизированная фармацевтическая композиция, cодержащая доцетаксель | |
| JP2015007136A5 (enExample) | ||
| JP2015147763A (ja) | ピリジルアミノ酢酸化合物含有医薬組成物 | |
| JP2017186372A5 (enExample) | ||
| PE20220953A1 (es) | Formulaciones de insulina y glucagon inyectables por via subcutanea y metodos de administracion | |
| RU2020138655A (ru) | Жидкие лекарственные формы, содержащие 2,7-бис[2-(диэтиламино)этокси]флуорен-9-она дигидрохлорид | |
| NZ721530B2 (en) | Pyridylaminoacetic acid compound and polyoxyethylene castor oil-containing pharmaceutical composition |