JP2016053051A5 - - Google Patents
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- JP2016053051A5 JP2016053051A5 JP2015205977A JP2015205977A JP2016053051A5 JP 2016053051 A5 JP2016053051 A5 JP 2016053051A5 JP 2015205977 A JP2015205977 A JP 2015205977A JP 2015205977 A JP2015205977 A JP 2015205977A JP 2016053051 A5 JP2016053051 A5 JP 2016053051A5
- Authority
- JP
- Japan
- Prior art keywords
- polysaccharide
- cdt
- carrier protein
- organic solvent
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21914309P | 2009-06-22 | 2009-06-22 | |
| US21915109P | 2009-06-22 | 2009-06-22 | |
| US61/219,143 | 2009-06-22 | ||
| US61/219,151 | 2009-06-22 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013161040A Division JP2013237693A (ja) | 2009-06-22 | 2013-08-02 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017106213A Division JP6393804B2 (ja) | 2009-06-22 | 2017-05-30 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016053051A JP2016053051A (ja) | 2016-04-14 |
| JP2016053051A5 true JP2016053051A5 (enExample) | 2016-06-02 |
| JP6153581B2 JP6153581B2 (ja) | 2017-06-28 |
Family
ID=43599164
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517649A Pending JP2012530785A (ja) | 2009-06-22 | 2010-06-22 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
| JP2013161040A Pending JP2013237693A (ja) | 2009-06-22 | 2013-08-02 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
| JP2015205977A Expired - Fee Related JP6153581B2 (ja) | 2009-06-22 | 2015-10-20 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
| JP2017106213A Expired - Fee Related JP6393804B2 (ja) | 2009-06-22 | 2017-05-30 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517649A Pending JP2012530785A (ja) | 2009-06-22 | 2010-06-22 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
| JP2013161040A Pending JP2013237693A (ja) | 2009-06-22 | 2013-08-02 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017106213A Expired - Fee Related JP6393804B2 (ja) | 2009-06-22 | 2017-05-30 | 組成物および黄色ブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）血清型５および８莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9125951B2 (enExample) |
| EP (2) | EP3461496B1 (enExample) |
| JP (4) | JP2012530785A (enExample) |
| KR (2) | KR101774062B1 (enExample) |
| CN (1) | CN102625713A (enExample) |
| AR (1) | AR077190A1 (enExample) |
| AU (1) | AU2010301043B2 (enExample) |
| BR (1) | BRPI1011753B8 (enExample) |
| CA (1) | CA2766418C (enExample) |
| CO (1) | CO6480930A2 (enExample) |
| ES (2) | ES2959890T3 (enExample) |
| IL (1) | IL217085B (enExample) |
| MX (1) | MX2012000045A (enExample) |
| MY (1) | MY158231A (enExample) |
| NZ (1) | NZ597191A (enExample) |
| PE (1) | PE20110065A1 (enExample) |
| PH (2) | PH12015502508A1 (enExample) |
| RU (1) | RU2531234C2 (enExample) |
| SA (1) | SA114350400B1 (enExample) |
| SG (2) | SG177310A1 (enExample) |
| TW (2) | TWI505834B (enExample) |
| WO (1) | WO2011041003A2 (enExample) |
Families Citing this family (30)
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| SI2445522T1 (sl) | 2009-06-22 | 2017-10-30 | Wyeth Llc | Imunogeni sestavki antigenov Staphylococcusa aureusa |
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| BR112012010223A2 (pt) | 2009-10-30 | 2016-12-06 | Novartis Ag | purificação de staphylococcus aureus tipo 5 e tipo 8 sacarídeos capsulares |
| AR091902A1 (es) | 2012-07-25 | 2015-03-11 | Hanmi Pharm Ind Co Ltd | Formulacion liquida de un conjugado de insulina de accion prolongada |
| EP3421051B1 (en) | 2012-08-16 | 2020-05-13 | Pfizer Inc | Glycoconjugation processes and compositions |
| BR112015011722B1 (pt) | 2012-11-21 | 2022-08-09 | Serum Institute Of India Ltd | Método para preparar um polissacarídeo capsular de neisseria meningitidis x |
| GB201310008D0 (en) | 2013-06-05 | 2013-07-17 | Glaxosmithkline Biolog Sa | Immunogenic composition for use in therapy |
| HRP20211288T1 (hr) * | 2014-01-21 | 2021-11-26 | Pfizer Inc. | Kapsularni polisaharidi bakterije streptococcus pneumoniae i njihovi konjugati |
| CN106714820A (zh) * | 2014-05-12 | 2017-05-24 | 普渡研究基金会 | 选择素及icam/vcam肽配体偶联物 |
| MX378792B (es) * | 2014-08-08 | 2025-03-10 | Glaxosmithkline Biologicals Sa | Células hospederas modificadas y oligosacáridos híbridos para su uso en producción de bioconjugados. |
| WO2016091904A1 (en) | 2014-12-10 | 2016-06-16 | Glaxosmithkline Biologicals Sa | Method of treatment |
| RU2692923C2 (ru) * | 2015-05-04 | 2019-06-28 | Пфайзер Инк. | Конъюгаты полисахарида стрептококка группы В и белка, способы получения конъюгатов, иммуногенные композиции, содержащие конъюгаты, и их применения |
| IL303998A (en) * | 2015-07-21 | 2023-08-01 | Pfizer | Immunogenic preparations containing conjugated capsular sugar antigens, kits containing them and their uses |
| KR102824686B1 (ko) * | 2016-02-15 | 2025-06-25 | 히프라 사이언티픽, 에스.엘.유 | 면역원성 작용제로서 스트렙토코쿠스 우베리스 추출물 |
| KR102428253B1 (ko) * | 2016-03-15 | 2022-08-02 | 엠에스디 웰컴 트러스트 힐레맨 랩스 피브이티. 리미티드 | 신규한 다당류-단백질 접합체 및 이의 제조방법 |
| US11400162B2 (en) | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| US11090374B2 (en) * | 2017-02-24 | 2021-08-17 | Merck Sharp & Dohme Corp. | Enhancing immunogenicity of Streptococcus pneumoniae polysaccharide-protein conjugates |
| US11389540B2 (en) | 2017-09-07 | 2022-07-19 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CA3074703A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| AU2018328040B2 (en) * | 2017-09-07 | 2025-01-16 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| EP3788143B1 (en) * | 2018-04-30 | 2023-06-28 | Merck Sharp & Dohme LLC | Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide |
| WO2019212846A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates |
| KR20210005161A (ko) | 2018-04-30 | 2021-01-13 | 머크 샤프 앤드 돔 코포레이션 | 리오스피어로부터 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법 |
| US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| JP7239509B6 (ja) | 2019-02-22 | 2023-03-28 | ファイザー・インク | 細菌多糖類を精製するための方法 |
| JP2021132644A (ja) | 2020-02-21 | 2021-09-13 | ファイザー・インク | 糖の精製 |
| CN111228478A (zh) * | 2020-02-25 | 2020-06-05 | 江南大学 | 三糖重复单元寡糖链在制备金黄色葡萄球菌疫苗中的应用 |
| US12138302B2 (en) | 2020-10-27 | 2024-11-12 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| US12357681B2 (en) | 2020-12-23 | 2025-07-15 | Pfizer Inc. | E. coli FimH mutants and uses thereof |
| JP2024521847A (ja) * | 2021-05-28 | 2024-06-04 | ファイザー・インク | コンジュゲート化莢膜糖抗原を含む免疫原性組成物およびその使用 |
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2010
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