JP2015532928A5 - - Google Patents
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- Publication number
- JP2015532928A5 JP2015532928A5 JP2015533220A JP2015533220A JP2015532928A5 JP 2015532928 A5 JP2015532928 A5 JP 2015532928A5 JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015532928 A5 JP2015532928 A5 JP 2015532928A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- shell
- type
- therapeutic agent
- biodegradable polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 27
- 239000003814 drug Substances 0.000 claims 24
- 229940124597 therapeutic agent Drugs 0.000 claims 24
- 239000003094 microcapsule Substances 0.000 claims 20
- 229920002988 biodegradable polymer Polymers 0.000 claims 18
- 239000004621 biodegradable polymer Substances 0.000 claims 18
- 239000000463 material Substances 0.000 claims 17
- 239000011859 microparticle Substances 0.000 claims 15
- 239000000945 filler Substances 0.000 claims 10
- 239000007788 liquid Substances 0.000 claims 4
- 239000000499 gel Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000011162 core material Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 229920005597 polymer membrane Polymers 0.000 claims 2
- 229920006237 degradable polymer Polymers 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 229920003169 water-soluble polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261703723P | 2012-09-20 | 2012-09-20 | |
| US61/703,723 | 2012-09-20 | ||
| PCT/US2013/060922 WO2014047439A1 (en) | 2012-09-20 | 2013-09-20 | Biodegradable microcapsules containing filling material |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018178572A Division JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015532928A JP2015532928A (ja) | 2015-11-16 |
| JP2015532928A5 true JP2015532928A5 (https=) | 2016-10-20 |
Family
ID=50341971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533220A Pending JP2015532928A (ja) | 2012-09-20 | 2013-09-20 | 充填材料を含有する生体分解可能なマイクロカプセル |
| JP2018178572A Pending JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018178572A Pending JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20150265541A1 (https=) |
| EP (1) | EP2897593A4 (https=) |
| JP (2) | JP2015532928A (https=) |
| KR (1) | KR20150090038A (https=) |
| AU (3) | AU2013317899A1 (https=) |
| BR (1) | BR112015006087A2 (https=) |
| HK (1) | HK1214127A1 (https=) |
| MX (2) | MX2015003665A (https=) |
| WO (1) | WO2014047439A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011106702A2 (en) | 2010-02-25 | 2011-09-01 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
| EP2804632B1 (en) | 2012-01-19 | 2019-09-18 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
| US8962577B2 (en) | 2012-03-16 | 2015-02-24 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
| JP6138904B2 (ja) | 2012-03-16 | 2017-05-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート |
| JP6360039B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法 |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| ES3055223T3 (en) | 2012-05-03 | 2026-02-10 | Alcon Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| AU2013256008B2 (en) | 2012-05-04 | 2016-02-25 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
| US10568975B2 (en) | 2013-02-05 | 2020-02-25 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| WO2015127368A1 (en) | 2014-02-23 | 2015-08-27 | The Johns Hopkins University | Hypotonic microbicidal formulations and methods of use |
| KR20240126072A (ko) | 2015-01-27 | 2024-08-20 | 더 존스 홉킨스 유니버시티 | 점막표면에서 활성제의 향상된 수송을 위한 저장성 하이드로겔 제제 |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| US20170273911A1 (en) * | 2016-03-23 | 2017-09-28 | Boston Scientific Scimed Inc. | Injectable microspheres |
| ES2990061T3 (es) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Degronímeros espirocíclicos para la degradación de proteínas diana |
| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| SG11201811491YA (en) | 2016-06-27 | 2019-01-30 | Achillion Pharmaceuticals Inc | Quinazoline and indole compounds to treat medical disorders |
| RU2019102647A (ru) | 2016-07-01 | 2020-08-03 | Г1 Терапьютикс, Инк. | Антипролиферационные средства на основе пиримидина |
| CN109862945B (zh) * | 2016-10-28 | 2022-03-08 | 联合利华知识产权控股有限公司 | 包含颗粒的个人护理组合物 |
| BR112019008463B1 (pt) | 2016-10-28 | 2022-06-07 | Unilever Ip Holdings B.V. | Composição para a higiene pessoal |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| EP3773576A4 (en) | 2018-03-26 | 2021-12-29 | C4 Therapeutics, Inc. | Cereblon binders for the degradation of ikaros |
| US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| WO2020149684A2 (ko) * | 2019-01-18 | 2020-07-23 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| KR102272566B1 (ko) * | 2019-01-18 | 2021-07-05 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| FR3091877B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de detergence avec des propriétés olfactives améliorées |
| FR3091878B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de produits d’entretien avec des propriétés olfactives améliorées |
| US12496279B2 (en) | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
| WO2020210630A1 (en) | 2019-04-12 | 2020-10-15 | C4 Therapeutics, Inc. | Tricyclic degraders of ikaros and aiolos |
| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
| TW202146412A (zh) | 2020-03-05 | 2021-12-16 | 美商Ｃ４醫藥公司 | 用於標靶降解brd9之化合物 |
| KR20230012547A (ko) | 2020-05-19 | 2023-01-26 | 쥐원 쎄라퓨틱스, 인크. | 의학적 장애의 치료를 위한 시클린-의존성 키나제 억제 화합물 |
| CN116437913A (zh) | 2020-09-23 | 2023-07-14 | 艾其林医药公司 | 用于治疗补体介导的病症的药物化合物 |
| WO2024184188A1 (en) * | 2023-03-03 | 2024-09-12 | Danmarks Tekniske Universitet | A method for preparing microparticles for drug delivery |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001388A (en) * | 1973-06-14 | 1977-01-04 | Alza Corporation | Ophthalmological bioerodible drug dispensing formulation |
| US4865846A (en) * | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| AU2001298061A1 (en) * | 2000-12-13 | 2003-07-09 | Purdue Research Foundation | Microencapsulation of drugs by solvent exchange |
| US8425929B2 (en) * | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| MX2007003789A (es) * | 2004-10-04 | 2007-07-20 | Qlt Usa Inc | Suministro ocular de formulaciones polimericas para suministro. |
| JP4856881B2 (ja) * | 2005-02-01 | 2012-01-18 | 川澄化学工業株式会社 | 薬剤徐放システム |
| BRPI0615563A2 (pt) * | 2005-09-07 | 2011-05-24 | Southwest Res Inst | formulações farmacêuticas em micropartìcula biodegradável exibindo taxas de liberação aperfeiçoadas |
| JP5201763B2 (ja) * | 2007-02-28 | 2013-06-05 | 昇一 城武 | 異なる平均粒径サイズの粒子からなる混合微粒子カプセルの製造方法 |
| US8071119B2 (en) * | 2007-05-14 | 2011-12-06 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
| CA2700356C (en) * | 2007-09-27 | 2013-07-09 | Akina, Inc. | Sol-gel phase-reversible hydrogel templates and uses thereof |
| US20130316010A1 (en) * | 2010-10-18 | 2013-11-28 | Case Western Reserve University | Polymeric microparticles |
-
2013
- 2013-09-20 KR KR1020157010168A patent/KR20150090038A/ko not_active Ceased
- 2013-09-20 WO PCT/US2013/060922 patent/WO2014047439A1/en not_active Ceased
- 2013-09-20 AU AU2013317899A patent/AU2013317899A1/en not_active Abandoned
- 2013-09-20 MX MX2015003665A patent/MX2015003665A/es unknown
- 2013-09-20 JP JP2015533220A patent/JP2015532928A/ja active Pending
- 2013-09-20 US US14/429,304 patent/US20150265541A1/en not_active Abandoned
- 2013-09-20 HK HK16101050.7A patent/HK1214127A1/zh unknown
- 2013-09-20 BR BR112015006087A patent/BR112015006087A2/pt not_active IP Right Cessation
- 2013-09-20 EP EP13838732.9A patent/EP2897593A4/en not_active Withdrawn
-
2015
- 2015-03-20 MX MX2019002575A patent/MX2019002575A/es unknown
-
2017
- 2017-12-05 US US15/832,368 patent/US20180185296A1/en not_active Abandoned
-
2018
- 2018-06-22 AU AU2018204552A patent/AU2018204552A1/en not_active Abandoned
- 2018-09-25 JP JP2018178572A patent/JP2019014729A/ja active Pending
-
2020
- 2020-04-23 AU AU2020202735A patent/AU2020202735A1/en not_active Abandoned
- 2020-05-26 US US16/883,917 patent/US20200390715A1/en not_active Abandoned
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