JP2015532928A - 充填材料を含有する生体分解可能なマイクロカプセル - Google Patents

充填材料を含有する生体分解可能なマイクロカプセル Download PDF

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Publication number
JP2015532928A
JP2015532928A JP2015533220A JP2015533220A JP2015532928A JP 2015532928 A JP2015532928 A JP 2015532928A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015532928 A JP2015532928 A JP 2015532928A
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JP
Japan
Prior art keywords
composition
shell
microcapsules
therapeutic agent
type
Prior art date
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Pending
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JP2015533220A
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English (en)
Japanese (ja)
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JP2015532928A5 (https=
Inventor
キナム パク，
キナム パク，
クリストファー エー． ローズ，
クリストファー エー． ローズ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akina Inc
OHR Pharma LLC
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Akina Inc
OHR Pharma LLC
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Publication of JP2015532928A publication Critical patent/JP2015532928A/ja
Publication of JP2015532928A5 publication Critical patent/JP2015532928A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Dermatology (AREA)
JP2015533220A 2012-09-20 2013-09-20 充填材料を含有する生体分解可能なマイクロカプセル Pending JP2015532928A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261703723P 2012-09-20 2012-09-20
US61/703,723 2012-09-20
PCT/US2013/060922 WO2014047439A1 (en) 2012-09-20 2013-09-20 Biodegradable microcapsules containing filling material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018178572A Division JP2019014729A (ja) 2012-09-20 2018-09-25 充填材料を含有する生体分解可能なマイクロカプセル

Publications (2)

Publication Number Publication Date
JP2015532928A true JP2015532928A (ja) 2015-11-16
JP2015532928A5 JP2015532928A5 (https=) 2016-10-20

Family

ID=50341971

Family Applications (2)

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JP2015533220A Pending JP2015532928A (ja) 2012-09-20 2013-09-20 充填材料を含有する生体分解可能なマイクロカプセル
JP2018178572A Pending JP2019014729A (ja) 2012-09-20 2018-09-25 充填材料を含有する生体分解可能なマイクロカプセル

Family Applications After (1)

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JP2018178572A Pending JP2019014729A (ja) 2012-09-20 2018-09-25 充填材料を含有する生体分解可能なマイクロカプセル

Country Status (9)

Country Link
US (3) US20150265541A1 (https=)
EP (1) EP2897593A4 (https=)
JP (2) JP2015532928A (https=)
KR (1) KR20150090038A (https=)
AU (3) AU2013317899A1 (https=)
BR (1) BR112015006087A2 (https=)
HK (1) HK1214127A1 (https=)
MX (2) MX2015003665A (https=)
WO (1) WO2014047439A1 (https=)

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US8962577B2 (en) 2012-03-16 2015-02-24 The Johns Hopkins University Controlled release formulations for the delivery of HIF-1 inhibitors
JP6138904B2 (ja) 2012-03-16 2017-05-31 ザ・ジョンズ・ホプキンス・ユニバーシティー 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート
JP6360039B2 (ja) 2012-05-03 2018-07-18 カラ ファーマシューティカルズ インコーポレイテッド 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法
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US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
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BR112019008463B1 (pt) 2016-10-28 2022-06-07 Unilever Ip Holdings B.V. Composição para a higiene pessoal
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
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Also Published As

Publication number Publication date
MX2015003665A (es) 2016-03-08
WO2014047439A1 (en) 2014-03-27
JP2019014729A (ja) 2019-01-31
AU2020202735A1 (en) 2020-05-14
US20200390715A1 (en) 2020-12-17
KR20150090038A (ko) 2015-08-05
US20150265541A1 (en) 2015-09-24
MX2019002575A (es) 2019-10-30
EP2897593A4 (en) 2016-04-06
AU2018204552A1 (en) 2018-07-12
BR112015006087A2 (pt) 2017-07-04
US20180185296A1 (en) 2018-07-05
AU2013317899A8 (en) 2015-05-28
AU2013317899A1 (en) 2015-05-07
EP2897593A1 (en) 2015-07-29
HK1214127A1 (zh) 2016-10-07

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