BR112015006087A2 - microcápsulas biodegradáveis contendo material de enchimento - Google Patents
microcápsulas biodegradáveis contendo material de enchimentoInfo
- Publication number
- BR112015006087A2 BR112015006087A2 BR112015006087A BR112015006087A BR112015006087A2 BR 112015006087 A2 BR112015006087 A2 BR 112015006087A2 BR 112015006087 A BR112015006087 A BR 112015006087A BR 112015006087 A BR112015006087 A BR 112015006087A BR 112015006087 A2 BR112015006087 A2 BR 112015006087A2
- Authority
- BR
- Brazil
- Prior art keywords
- biodegradable
- filling material
- microcapsules containing
- polymer shell
- biodegradable microcapsules
- Prior art date
Links
- 239000003094 microcapsule Substances 0.000 title abstract 5
- 239000000945 filler Substances 0.000 title abstract 4
- 239000000463 material Substances 0.000 abstract 8
- 229920002988 biodegradable polymer Polymers 0.000 abstract 2
- 239000004621 biodegradable polymer Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000011859 microparticle Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Dermatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261703723P | 2012-09-20 | 2012-09-20 | |
| PCT/US2013/060922 WO2014047439A1 (en) | 2012-09-20 | 2013-09-20 | Biodegradable microcapsules containing filling material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015006087A2 true BR112015006087A2 (pt) | 2017-07-04 |
Family
ID=50341971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015006087A BR112015006087A2 (pt) | 2012-09-20 | 2013-09-20 | microcápsulas biodegradáveis contendo material de enchimento |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20150265541A1 (https=) |
| EP (1) | EP2897593A4 (https=) |
| JP (2) | JP2015532928A (https=) |
| KR (1) | KR20150090038A (https=) |
| AU (3) | AU2013317899A1 (https=) |
| BR (1) | BR112015006087A2 (https=) |
| HK (1) | HK1214127A1 (https=) |
| MX (2) | MX2015003665A (https=) |
| WO (1) | WO2014047439A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2538929A4 (en) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE |
| US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
| CA2863632C (en) | 2012-01-19 | 2017-07-11 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
| US8962577B2 (en) | 2012-03-16 | 2015-02-24 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
| JP6138904B2 (ja) | 2012-03-16 | 2017-05-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート |
| KR102310775B1 (ko) | 2012-05-03 | 2021-10-07 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| AU2013256064B2 (en) | 2012-05-03 | 2018-01-04 | Alcon Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| AU2013256008B2 (en) | 2012-05-04 | 2016-02-25 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
| WO2014124006A1 (en) | 2013-02-05 | 2014-08-14 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| WO2015127368A1 (en) | 2014-02-23 | 2015-08-27 | The Johns Hopkins University | Hypotonic microbicidal formulations and methods of use |
| CN107635545A (zh) | 2015-01-27 | 2018-01-26 | 约翰霍普金斯大学 | 用于增强粘膜表面处活性剂的输送的低渗水凝胶制剂 |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| US20170273911A1 (en) * | 2016-03-23 | 2017-09-28 | Boston Scientific Scimed Inc. | Injectable microspheres |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| EP3454862B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| EP4491236A3 (en) | 2016-05-10 | 2025-04-02 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| RU2018145364A (ru) | 2016-06-27 | 2020-07-28 | Ачиллион Фармасьютикалс, Инк. | Хиназолиновые и индольные соединения для лечения медицинских нарушений |
| EP3858835A1 (en) | 2016-07-01 | 2021-08-04 | G1 Therapeutics, Inc. | Pyrimidine-based antiproliferative agents |
| CN109862945B (zh) * | 2016-10-28 | 2022-03-08 | 联合利华知识产权控股有限公司 | 包含颗粒的个人护理组合物 |
| BR112019008463B1 (pt) | 2016-10-28 | 2022-06-07 | Unilever Ip Holdings B.V. | Composição para a higiene pessoal |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| EP4717317A2 (en) | 2017-06-20 | 2026-04-01 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー4 セラピューティクス, インコーポレイテッド | Ikarosの分解のためのセレブロン結合剤 |
| WO2020041301A1 (en) | 2018-08-20 | 2020-02-27 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| WO2020051532A2 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| WO2020149684A2 (ko) * | 2019-01-18 | 2020-07-23 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| KR102272566B1 (ko) * | 2019-01-18 | 2021-07-05 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| FR3091878B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de produits d’entretien avec des propriétés olfactives améliorées |
| FR3091877B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de detergence avec des propriétés olfactives améliorées |
| US12496279B2 (en) | 2019-04-11 | 2025-12-16 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
| CN120172958A (zh) | 2019-04-12 | 2025-06-20 | C4医药公司 | Ikaros和aiolos的三环降解物 |
| WO2021168320A1 (en) | 2020-02-20 | 2021-08-26 | Achillion Pharmaceuticals, Inc. | Heteroaryl compounds for treatment of complement factor d mediated disorders |
| AU2021231898A1 (en) | 2020-03-05 | 2022-10-27 | C4 Therapeutics, Inc. | Compounds for targeted degradation of BRD9 |
| ES3048084T3 (en) | 2020-05-19 | 2025-12-09 | Pharmacosmos Holding As | Cyclin-dependent kinase inhibiting compounds for the treatment of medical disorders |
| WO2022066774A1 (en) | 2020-09-23 | 2022-03-31 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement mediated disorders |
| WO2024184188A1 (en) * | 2023-03-03 | 2024-09-12 | Danmarks Tekniske Universitet | A method for preparing microparticles for drug delivery |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001388A (en) * | 1973-06-14 | 1977-01-04 | Alza Corporation | Ophthalmological bioerodible drug dispensing formulation |
| US4865846A (en) * | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| AU2001298061A1 (en) * | 2000-12-13 | 2003-07-09 | Purdue Research Foundation | Microencapsulation of drugs by solvent exchange |
| US8425929B2 (en) * | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| BRPI0516308A2 (pt) * | 2004-10-04 | 2010-06-15 | Qlt Usa Inc | composição fluida, métodos de tratamento de uma doença ou disfunção, métodos de liberação local ou sistêmica de um agente biológico, implantes, método de formação de um implante, kit de agente biológico e usos de uma composição fluida |
| JP4856881B2 (ja) * | 2005-02-01 | 2012-01-18 | 川澄化学工業株式会社 | 薬剤徐放システム |
| KR20080059175A (ko) * | 2005-09-07 | 2008-06-26 | 사우스웨스트 리서치 인스티튜트 | 방출속도가 향상된 생분해성 미립자 약제학적 제제 |
| JP5201763B2 (ja) * | 2007-02-28 | 2013-06-05 | 昇一 城武 | 異なる平均粒径サイズの粒子からなる混合微粒子カプセルの製造方法 |
| US8071119B2 (en) * | 2007-05-14 | 2011-12-06 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
| CA2700356C (en) * | 2007-09-27 | 2013-07-09 | Akina, Inc. | Sol-gel phase-reversible hydrogel templates and uses thereof |
| US20130316010A1 (en) * | 2010-10-18 | 2013-11-28 | Case Western Reserve University | Polymeric microparticles |
-
2013
- 2013-09-20 JP JP2015533220A patent/JP2015532928A/ja active Pending
- 2013-09-20 AU AU2013317899A patent/AU2013317899A1/en not_active Abandoned
- 2013-09-20 HK HK16101050.7A patent/HK1214127A1/zh unknown
- 2013-09-20 EP EP13838732.9A patent/EP2897593A4/en not_active Withdrawn
- 2013-09-20 WO PCT/US2013/060922 patent/WO2014047439A1/en not_active Ceased
- 2013-09-20 US US14/429,304 patent/US20150265541A1/en not_active Abandoned
- 2013-09-20 KR KR1020157010168A patent/KR20150090038A/ko not_active Ceased
- 2013-09-20 MX MX2015003665A patent/MX2015003665A/es unknown
- 2013-09-20 BR BR112015006087A patent/BR112015006087A2/pt not_active IP Right Cessation
-
2015
- 2015-03-20 MX MX2019002575A patent/MX2019002575A/es unknown
-
2017
- 2017-12-05 US US15/832,368 patent/US20180185296A1/en not_active Abandoned
-
2018
- 2018-06-22 AU AU2018204552A patent/AU2018204552A1/en not_active Abandoned
- 2018-09-25 JP JP2018178572A patent/JP2019014729A/ja active Pending
-
2020
- 2020-04-23 AU AU2020202735A patent/AU2020202735A1/en not_active Abandoned
- 2020-05-26 US US16/883,917 patent/US20200390715A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2019002575A (es) | 2019-10-30 |
| US20200390715A1 (en) | 2020-12-17 |
| KR20150090038A (ko) | 2015-08-05 |
| AU2013317899A1 (en) | 2015-05-07 |
| JP2015532928A (ja) | 2015-11-16 |
| MX2015003665A (es) | 2016-03-08 |
| HK1214127A1 (zh) | 2016-10-07 |
| AU2020202735A1 (en) | 2020-05-14 |
| WO2014047439A1 (en) | 2014-03-27 |
| EP2897593A1 (en) | 2015-07-29 |
| US20150265541A1 (en) | 2015-09-24 |
| AU2018204552A1 (en) | 2018-07-12 |
| EP2897593A4 (en) | 2016-04-06 |
| JP2019014729A (ja) | 2019-01-31 |
| US20180185296A1 (en) | 2018-07-05 |
| AU2013317899A8 (en) | 2015-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2599 DE 27-10-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |