JP2016508789A5 - - Google Patents
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- Publication number
- JP2016508789A5 JP2016508789A5 JP2015556594A JP2015556594A JP2016508789A5 JP 2016508789 A5 JP2016508789 A5 JP 2016508789A5 JP 2015556594 A JP2015556594 A JP 2015556594A JP 2015556594 A JP2015556594 A JP 2015556594A JP 2016508789 A5 JP2016508789 A5 JP 2016508789A5
- Authority
- JP
- Japan
- Prior art keywords
- intrauterine
- layer
- particulate material
- core
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011236 particulate material Substances 0.000 claims 13
- 239000003433 contraceptive agent Substances 0.000 claims 9
- 230000002254 contraceptive effect Effects 0.000 claims 9
- 239000000463 material Substances 0.000 claims 9
- 239000004480 active ingredient Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 4
- 229920001971 elastomer Polymers 0.000 claims 3
- 239000000806 elastomer Substances 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 229920001187 thermosetting polymer Polymers 0.000 claims 3
- 235000021355 Stearic acid Nutrition 0.000 claims 2
- 239000000440 bentonite Substances 0.000 claims 2
- 229910000278 bentonite Inorganic materials 0.000 claims 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims 2
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 claims 2
- 239000008116 calcium stearate Substances 0.000 claims 2
- 235000013539 calcium stearate Nutrition 0.000 claims 2
- 239000004927 clay Substances 0.000 claims 2
- 229910052570 clay Inorganic materials 0.000 claims 2
- 238000001125 extrusion Methods 0.000 claims 2
- 238000001746 injection moulding Methods 0.000 claims 2
- 235000019359 magnesium stearate Nutrition 0.000 claims 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 239000008117 stearic acid Substances 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- 239000000454 talc Substances 0.000 claims 2
- 229910052623 talc Inorganic materials 0.000 claims 2
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 235000011132 calcium sulphate Nutrition 0.000 claims 1
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 230000001076 estrogenic effect Effects 0.000 claims 1
- MVPICKVDHDWCJQ-UHFFFAOYSA-N ethyl 3-pyrrolidin-1-ylpropanoate Chemical compound CCOC(=O)CCN1CCCC1 MVPICKVDHDWCJQ-UHFFFAOYSA-N 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000011147 inorganic material Substances 0.000 claims 1
- 239000011368 organic material Substances 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- -1 polydimethylsiloxane Polymers 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 229940045902 sodium stearyl fumarate Drugs 0.000 claims 1
- 239000000934 spermatocidal agent Substances 0.000 claims 1
- 230000001150 spermicidal effect Effects 0.000 claims 1
- 229920001169 thermoplastic Polymers 0.000 claims 1
- 229920002725 thermoplastic elastomer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1350155-6 | 2013-02-08 | ||
| SE1350155 | 2013-02-08 | ||
| PCT/IB2014/058696 WO2014122563A1 (en) | 2013-02-08 | 2014-01-31 | An intra vaginal device, and a method of reducing the rate of diffusion of active ingredients in said intra vaginal device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016508789A JP2016508789A (ja) | 2016-03-24 |
| JP2016508789A5 true JP2016508789A5 (https=) | 2017-03-09 |
Family
ID=50115933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556594A Pending JP2016508789A (ja) | 2013-02-08 | 2014-01-31 | 膣内避妊具および該膣内避妊具における有効成分の拡散速度を減少させる方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9775905B2 (https=) |
| EP (1) | EP2953595B1 (https=) |
| JP (1) | JP2016508789A (https=) |
| ES (1) | ES2787882T3 (https=) |
| HU (1) | HUE049219T2 (https=) |
| WO (1) | WO2014122563A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE539540C2 (sv) | 2013-09-12 | 2017-10-10 | Qpharma Ab | Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar |
| CN108135910B (zh) * | 2015-05-13 | 2022-12-02 | 拜耳股份有限公司 | 长效药物递送装置及其在避孕中的用途 |
| CN108392310A (zh) * | 2018-02-28 | 2018-08-14 | 张晓光 | 免更换宫内节育器 |
| USD935018S1 (en) * | 2020-04-07 | 2021-11-02 | The Population Council, Inc. | Contraceptive |
| EP4215180A1 (en) * | 2022-01-21 | 2023-07-26 | Sever Pharma Solutions | A drug delivery system |
| EP4215181A1 (en) * | 2022-01-21 | 2023-07-26 | Sever Pharma Solutions | An intravaginal ring |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3845761A (en) * | 1970-06-02 | 1974-11-05 | Alza Corp | Intrauterine contraceptive anti-fertility device for the management of reproduction |
| US4069307A (en) | 1970-10-01 | 1978-01-17 | Alza Corporation | Drug-delivery device comprising certain polymeric materials for controlled release of drug |
| US3903880A (en) * | 1972-08-17 | 1975-09-09 | Alza Corp | Intrauterine device for managing the reproductive process |
| DD114905A5 (https=) | 1973-12-06 | 1975-09-05 | ||
| US4292965A (en) * | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| US4728478A (en) * | 1982-08-05 | 1988-03-01 | Allied-Signal Inc. | Polymer films containing platelet particles |
| US4601714A (en) * | 1983-07-07 | 1986-07-22 | Burnhill Michael S | Vaginal device |
| US5972372A (en) | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| US6821928B2 (en) * | 2001-11-06 | 2004-11-23 | Rodney Ruskin | Method to reduce the rate of diffusion of slow-release materials through polymers and process for making drip irrigation devices with long-term control of root growth |
| US20040213846A1 (en) * | 2003-04-23 | 2004-10-28 | Greenblatt Gary David | Polymer-clay nanocomposite for extended release of active ingredient |
| US20060251824A1 (en) * | 2005-05-05 | 2006-11-09 | Boulais Dennis R | Coating of medical devices with solids |
| EP2170276B1 (en) | 2007-06-26 | 2018-08-22 | Allergan Pharmaceuticals International Limited | Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs |
| EP2359807B1 (en) * | 2008-02-04 | 2017-07-26 | Ferring B.V. | Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof |
| WO2013013172A1 (en) * | 2011-07-20 | 2013-01-24 | The University Of Utah Research Foundation | Intravaginal devices for drug delivery |
| BR112014014600A2 (pt) * | 2011-12-16 | 2017-06-13 | Combinent Biomedical Systems Inc | dispositivos para administração vaginal de fármacos e métodos de fabricação |
-
2014
- 2014-01-31 WO PCT/IB2014/058696 patent/WO2014122563A1/en not_active Ceased
- 2014-01-31 ES ES14705219T patent/ES2787882T3/es active Active
- 2014-01-31 EP EP14705219.5A patent/EP2953595B1/en active Active
- 2014-01-31 HU HUE14705219A patent/HUE049219T2/hu unknown
- 2014-01-31 US US14/766,121 patent/US9775905B2/en active Active
- 2014-01-31 JP JP2015556594A patent/JP2016508789A/ja active Pending
-
2017
- 2017-05-19 US US15/600,299 patent/US11872284B2/en active Active
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