JP2015529447A5 - - Google Patents
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- Publication number
- JP2015529447A5 JP2015529447A5 JP2015518459A JP2015518459A JP2015529447A5 JP 2015529447 A5 JP2015529447 A5 JP 2015529447A5 JP 2015518459 A JP2015518459 A JP 2015518459A JP 2015518459 A JP2015518459 A JP 2015518459A JP 2015529447 A5 JP2015529447 A5 JP 2015529447A5
- Authority
- JP
- Japan
- Prior art keywords
- filtration
- use according
- mbar
- cell culture
- culture medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001914 filtration Methods 0.000 claims description 49
- 238000000034 method Methods 0.000 claims description 40
- 230000003612 virological effect Effects 0.000 claims description 22
- 238000002360 preparation method Methods 0.000 claims description 21
- 239000006143 cell culture medium Substances 0.000 claims description 19
- 239000000356 contaminant Substances 0.000 claims description 16
- 241000700605 Viruses Species 0.000 claims description 10
- 239000002537 cosmetic Substances 0.000 claims description 5
- 235000010469 Glycine max Nutrition 0.000 claims description 4
- 244000068988 Glycine max Species 0.000 claims description 4
- 238000004113 cell culture Methods 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000011148 porous material Substances 0.000 claims description 4
- 239000000413 hydrolysate Substances 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 4
- 239000012502 diagnostic product Substances 0.000 claims 3
- 229940127557 pharmaceutical product Drugs 0.000 claims 3
- 239000000047 product Substances 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261662814P | 2012-06-21 | 2012-06-21 | |
| US61/662,814 | 2012-06-21 | ||
| PCT/US2013/045663 WO2013192009A1 (en) | 2012-06-21 | 2013-06-13 | Virus filtration of cell culture media |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017137031A Division JP6557706B2 (ja) | 2012-06-21 | 2017-07-13 | 細胞培養培地のウイルスろ過 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529447A JP2015529447A (ja) | 2015-10-08 |
| JP2015529447A5 true JP2015529447A5 (enExample) | 2016-09-15 |
| JP6220392B2 JP6220392B2 (ja) | 2017-10-25 |
Family
ID=48672845
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015518459A Active JP6220392B2 (ja) | 2012-06-21 | 2013-06-13 | 細胞培養培地のウイルスろ過 |
| JP2017137031A Expired - Fee Related JP6557706B2 (ja) | 2012-06-21 | 2017-07-13 | 細胞培養培地のウイルスろ過 |
| JP2018213613A Withdrawn JP2019022526A (ja) | 2012-06-21 | 2018-11-14 | 細胞培養培地のウイルスろ過 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017137031A Expired - Fee Related JP6557706B2 (ja) | 2012-06-21 | 2017-07-13 | 細胞培養培地のウイルスろ過 |
| JP2018213613A Withdrawn JP2019022526A (ja) | 2012-06-21 | 2018-11-14 | 細胞培養培地のウイルスろ過 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US9670456B2 (enExample) |
| EP (2) | EP3103861B1 (enExample) |
| JP (3) | JP6220392B2 (enExample) |
| KR (2) | KR102008048B1 (enExample) |
| CN (2) | CN108795724A (enExample) |
| AR (1) | AR092847A1 (enExample) |
| AU (2) | AU2013277532B2 (enExample) |
| BR (1) | BR112014031842B1 (enExample) |
| CA (1) | CA2876473C (enExample) |
| CO (1) | CO7151484A2 (enExample) |
| DK (2) | DK2732020T3 (enExample) |
| EA (2) | EA033006B1 (enExample) |
| ES (2) | ES2601429T3 (enExample) |
| HR (1) | HRP20161435T1 (enExample) |
| HU (1) | HUE031601T2 (enExample) |
| IL (2) | IL236073B (enExample) |
| IN (1) | IN2014DN10441A (enExample) |
| MX (2) | MX386767B (enExample) |
| MY (2) | MY195362A (enExample) |
| NZ (1) | NZ629083A (enExample) |
| PL (2) | PL3103861T3 (enExample) |
| PT (2) | PT3103861T (enExample) |
| SG (2) | SG10201701721TA (enExample) |
| SI (1) | SI2732020T1 (enExample) |
| TW (2) | TWI698522B (enExample) |
| WO (1) | WO2013192009A1 (enExample) |
| ZA (1) | ZA201409253B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY195362A (en) * | 2012-06-21 | 2023-01-16 | Baxalta Inc | Virus Filtration of Cell Culture Media |
| AR095196A1 (es) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | Medio de cultivo celular libre de suero |
| SG10201507931QA (en) * | 2014-12-22 | 2016-07-28 | Emd Millipore Corp | Removal of microorganisms from cell culture media |
| WO2016154290A1 (en) * | 2015-03-23 | 2016-09-29 | Alexion Pharmaceuticals, Inc. | Virus filtration |
| EP3015542A1 (de) * | 2015-05-07 | 2016-05-04 | Bayer Technology Services GmbH | Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes |
| TW202440903A (zh) | 2015-08-04 | 2024-10-16 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法（一） |
| SG11201809051YA (en) * | 2016-04-15 | 2018-11-29 | Boehringer Ingelheim Int | Cell retention device and method |
| WO2018107099A1 (en) * | 2016-12-09 | 2018-06-14 | Lonza Ltd | Method for the reduction of viral titer in pharmaceuticals |
| MX2020000228A (es) * | 2017-07-06 | 2020-08-10 | Regeneron Pharma | Proceso de cultivo celular para producir una glicoproteina. |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| MX2021010891A (es) * | 2019-03-11 | 2021-12-10 | Genzyme Corp | Filtracion tangencial de virus. |
| AU2020253381A1 (en) * | 2019-04-03 | 2021-12-02 | Genzyme Corporation | Continuous production of recombinant proteins |
| US12297451B1 (en) | 2019-10-25 | 2025-05-13 | Regeneron Pharmaceuticals, Inc. | Cell culture medium |
| US20230181796A1 (en) * | 2020-05-14 | 2023-06-15 | North Carolina State University | Fast automated approach for the derivation of acellular extracellular matrix scaffolds from tissues |
| CA3197305A1 (en) * | 2020-10-02 | 2022-04-07 | Regeneron Pharmaceuticals, Inc. | Continuous virus retentive filtration |
| WO2025019797A2 (en) * | 2023-07-19 | 2025-01-23 | Hatchless Inc. | System and method for low-cost sterilization of liquids |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0422874A (ja) * | 1990-05-16 | 1992-01-27 | Matsushita Electric Ind Co Ltd | 波形表示装置 |
| GB2352652A (en) | 1999-08-06 | 2001-02-07 | Fsm Technologies Ltd | Pre-treating hollow fibre membranes for micro-organism detection |
| US6485686B1 (en) * | 1999-09-17 | 2002-11-26 | The United States Of America As Represented By The Secretary Of The Army | Method and apparatus for counting submicron sized particles |
| AU1811301A (en) | 1999-12-02 | 2001-06-12 | General Hospital Corporation, The | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon |
| US6485688B1 (en) | 2000-04-24 | 2002-11-26 | General Electric Company | On-line sparging sampling and monitoring systems and methods |
| US6630016B2 (en) * | 2002-01-31 | 2003-10-07 | Koslow Technologies Corp. | Microporous filter media, filtration systems containing same, and methods of making and using |
| US6835311B2 (en) * | 2002-01-31 | 2004-12-28 | Koslow Technologies Corporation | Microporous filter media, filtration systems containing same, and methods of making and using |
| ES2214967B1 (es) * | 2003-03-06 | 2005-06-16 | Probitas Pharma, S.A | Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento. |
| PL1711513T3 (pl) * | 2003-12-01 | 2014-12-31 | Novo Nordisk Healthcare Ag | Nanofiltracja roztworów czynnika vii w celu usunięcia wirusów |
| DE102005047301B4 (de) * | 2005-09-30 | 2009-04-16 | Sartorius Stedim Biotech Gmbh | Verfahren zum Nachweis der Virenabreicherung für die Validierung von Filtern und Filtrationsprozessen |
| US20070084788A1 (en) * | 2005-10-14 | 2007-04-19 | Millipore Corporation | Ultrafiltration membranes and methods of making and use of ultrafiltration membranes |
| US8309029B1 (en) * | 2009-03-26 | 2012-11-13 | The United States Of America As Represented By The Secretary Of The Army | Virus and particulate separation from solution |
| US8945895B2 (en) * | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| SG10201408106WA (en) * | 2009-08-20 | 2015-01-29 | Baxter Int | Purification of vwf for increased removal of non-lipid enveloped viruses |
| MY195362A (en) * | 2012-06-21 | 2023-01-16 | Baxalta Inc | Virus Filtration of Cell Culture Media |
-
2013
- 2013-06-13 MY MYPI2018000283A patent/MY195362A/en unknown
- 2013-06-13 NZ NZ629083A patent/NZ629083A/en unknown
- 2013-06-13 MY MYPI2014003498A patent/MY173835A/en unknown
- 2013-06-13 EA EA201590059A patent/EA033006B1/ru not_active IP Right Cessation
- 2013-06-13 SG SG10201701721TA patent/SG10201701721TA/en unknown
- 2013-06-13 KR KR1020157001269A patent/KR102008048B1/ko active Active
- 2013-06-13 BR BR112014031842-5A patent/BR112014031842B1/pt not_active IP Right Cessation
- 2013-06-13 ES ES13731015.7T patent/ES2601429T3/es active Active
- 2013-06-13 SI SI201330369A patent/SI2732020T1/sl unknown
- 2013-06-13 CA CA2876473A patent/CA2876473C/en active Active
- 2013-06-13 EA EA201990887A patent/EA201990887A1/ru unknown
- 2013-06-13 HR HRP20161435TT patent/HRP20161435T1/hr unknown
- 2013-06-13 IN IN10441DEN2014 patent/IN2014DN10441A/en unknown
- 2013-06-13 SG SG11201408490PA patent/SG11201408490PA/en unknown
- 2013-06-13 DK DK13731015.7T patent/DK2732020T3/en active
- 2013-06-13 PT PT161818869T patent/PT3103861T/pt unknown
- 2013-06-13 WO PCT/US2013/045663 patent/WO2013192009A1/en not_active Ceased
- 2013-06-13 MX MX2017005169A patent/MX386767B/es unknown
- 2013-06-13 CN CN201810569534.4A patent/CN108795724A/zh active Pending
- 2013-06-13 HU HUE13731015A patent/HUE031601T2/hu unknown
- 2013-06-13 DK DK16181886.9T patent/DK3103861T3/da active
- 2013-06-13 EP EP16181886.9A patent/EP3103861B1/en active Active
- 2013-06-13 KR KR1020197022413A patent/KR20190092618A/ko not_active Ceased
- 2013-06-13 ES ES16181886T patent/ES2829968T3/es active Active
- 2013-06-13 PT PT137310157T patent/PT2732020T/pt unknown
- 2013-06-13 JP JP2015518459A patent/JP6220392B2/ja active Active
- 2013-06-13 PL PL16181886.9T patent/PL3103861T3/pl unknown
- 2013-06-13 PL PL13731015T patent/PL2732020T3/pl unknown
- 2013-06-13 MX MX2014015950A patent/MX347319B/es active IP Right Grant
- 2013-06-13 AU AU2013277532A patent/AU2013277532B2/en active Active
- 2013-06-13 EP EP13731015.7A patent/EP2732020B1/en active Active
- 2013-06-13 CN CN201380032998.7A patent/CN104640969A/zh active Pending
- 2013-06-19 TW TW106136343A patent/TWI698522B/zh active
- 2013-06-19 AR ARP130102198A patent/AR092847A1/es active IP Right Grant
- 2013-06-19 TW TW102121710A patent/TWI609962B/zh active
- 2013-06-19 US US13/921,417 patent/US9670456B2/en active Active
-
2014
- 2014-12-04 IL IL236073A patent/IL236073B/en active IP Right Grant
- 2014-12-15 ZA ZA2014/09253A patent/ZA201409253B/en unknown
- 2014-12-17 CO CO14277524A patent/CO7151484A2/es unknown
-
2017
- 2017-03-27 US US15/470,064 patent/US20170260498A1/en not_active Abandoned
- 2017-07-13 JP JP2017137031A patent/JP6557706B2/ja not_active Expired - Fee Related
- 2017-09-12 AU AU2017228547A patent/AU2017228547B2/en active Active
-
2018
- 2018-11-14 JP JP2018213613A patent/JP2019022526A/ja not_active Withdrawn
- 2018-12-04 IL IL263479A patent/IL263479B/en active IP Right Grant
-
2020
- 2020-03-12 US US16/816,641 patent/US11421202B2/en active Active
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