CO7151484A2 - Filtración de virus de medios de cultivo celular - Google Patents
Filtración de virus de medios de cultivo celularInfo
- Publication number
- CO7151484A2 CO7151484A2 CO14277524A CO14277524A CO7151484A2 CO 7151484 A2 CO7151484 A2 CO 7151484A2 CO 14277524 A CO14277524 A CO 14277524A CO 14277524 A CO14277524 A CO 14277524A CO 7151484 A2 CO7151484 A2 CO 7151484A2
- Authority
- CO
- Colombia
- Prior art keywords
- cell culture
- culture medium
- preparation
- filtration
- preparations
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/26—Conditioning fluids entering or exiting the reaction vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/02—Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Filtering Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
La invención se refiere a un método para eliminar un contaminante viral de una preparación, que es un medio de cultivo celular o al menos un componente de un medio de cultivo celular. El método comprende someter dicha preparación a filtración durante al menos aproximadamente 24 horas a través de un filtro de virus que tiene un tamaño de poro efectivo de máximo aproximadamente 75 nm. Además, la invención se refiere al uso de un filtro de virus en la filtración por al menos aproximadamente 24 horas, en el que el filtro de virus tiene un tamaño de poro efectivo de máximo aproximadamente 75 nm para la eliminación del contaminante viral de la preparación, que es un medio de cultivo celular o al menos un componente de un medio de cultivo celular. En algunas implementaciones la filtración de acuerdo con la invención funciona a una capacidad volumétrica de al menos 2000 L/m 2 . Además, la invención se refiere al uso de una preparación, que es un medio de cultivo celular o al menos un imponente del medio de cultivo celular que se puede obtener de acuerdo con el método de la invención para el cultivo celular; preparaciones farmacéuticas, preparaciones de diagnóstico y/o preparaciones cosméticas, así como también preparaciones para alimentos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261662814P | 2012-06-21 | 2012-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO7151484A2 true CO7151484A2 (es) | 2014-12-29 |
Family
ID=48672845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO14277524A CO7151484A2 (es) | 2012-06-21 | 2014-12-17 | Filtración de virus de medios de cultivo celular |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US9670456B2 (es) |
| EP (2) | EP3103861B1 (es) |
| JP (3) | JP6220392B2 (es) |
| KR (2) | KR102008048B1 (es) |
| CN (2) | CN108795724A (es) |
| AR (1) | AR092847A1 (es) |
| AU (2) | AU2013277532B2 (es) |
| BR (1) | BR112014031842B1 (es) |
| CA (1) | CA2876473C (es) |
| CO (1) | CO7151484A2 (es) |
| DK (2) | DK3103861T3 (es) |
| EA (2) | EA033006B1 (es) |
| ES (2) | ES2601429T3 (es) |
| HK (2) | HK1198335A1 (es) |
| HR (1) | HRP20161435T1 (es) |
| HU (1) | HUE031601T2 (es) |
| IL (2) | IL236073B (es) |
| IN (1) | IN2014DN10441A (es) |
| MX (1) | MX347319B (es) |
| MY (2) | MY173835A (es) |
| NZ (1) | NZ629083A (es) |
| PL (2) | PL2732020T3 (es) |
| PT (2) | PT2732020T (es) |
| SG (2) | SG10201701721TA (es) |
| SI (1) | SI2732020T1 (es) |
| TW (2) | TWI698522B (es) |
| WO (1) | WO2013192009A1 (es) |
| ZA (1) | ZA201409253B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3103861T3 (da) * | 2012-06-21 | 2020-11-16 | Baxalta GmbH | Virusfiltrering af cellekulturmedier |
| AR095196A1 (es) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | Medio de cultivo celular libre de suero |
| SG10201507931QA (en) * | 2014-12-22 | 2016-07-28 | Emd Millipore Corp | Removal of microorganisms from cell culture media |
| WO2016154290A1 (en) * | 2015-03-23 | 2016-09-29 | Alexion Pharmaceuticals, Inc. | Virus filtration |
| EP3015542A1 (de) * | 2015-05-07 | 2016-05-04 | Bayer Technology Services GmbH | Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes |
| TW202330904A (zh) | 2015-08-04 | 2023-08-01 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法 |
| SG11201809051YA (en) * | 2016-04-15 | 2018-11-29 | Boehringer Ingelheim Int | Cell retention device and method |
| EP3535047A1 (en) * | 2016-12-09 | 2019-09-11 | Lonza Ltd | Method for the reduction of viral titer in pharmaceuticals |
| KR102659791B1 (ko) * | 2017-07-06 | 2024-04-23 | 리제너론 파마슈티칼스 인코포레이티드 | 당단백질을 만들기 위한 세포 배양 과정 |
| TW202003832A (zh) * | 2018-05-04 | 2020-01-16 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| KR20210134973A (ko) * | 2019-03-11 | 2021-11-11 | 젠자임 코포레이션 | 접선 흐름 바이러스 여과장치 |
| WO2021231956A1 (en) * | 2020-05-14 | 2021-11-18 | North Carolina State University | Fast automated approach for the derivation of acellular extracellular matrix scaffolds from tissues |
| MX2023003868A (es) * | 2020-10-02 | 2023-06-07 | Regeneron Pharma | Filtracion con retencion de virus continua. |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0422874A (ja) * | 1990-05-16 | 1992-01-27 | Matsushita Electric Ind Co Ltd | 波形表示装置 |
| GB2352652A (en) * | 1999-08-06 | 2001-02-07 | Fsm Technologies Ltd | Pre-treating hollow fibre membranes for micro-organism detection |
| US6485686B1 (en) * | 1999-09-17 | 2002-11-26 | The United States Of America As Represented By The Secretary Of The Army | Method and apparatus for counting submicron sized particles |
| US6861001B2 (en) | 1999-12-02 | 2005-03-01 | The General Hospital Corporation | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon |
| US6485688B1 (en) | 2000-04-24 | 2002-11-26 | General Electric Company | On-line sparging sampling and monitoring systems and methods |
| US6835311B2 (en) | 2002-01-31 | 2004-12-28 | Koslow Technologies Corporation | Microporous filter media, filtration systems containing same, and methods of making and using |
| US6630016B2 (en) * | 2002-01-31 | 2003-10-07 | Koslow Technologies Corp. | Microporous filter media, filtration systems containing same, and methods of making and using |
| ES2214967B1 (es) * | 2003-03-06 | 2005-06-16 | Probitas Pharma, S.A | Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento. |
| PT1711513E (pt) * | 2003-12-01 | 2014-10-02 | Novo Nordisk Healthcare Ag | Nanofiltração de soluções de fator vii para remover vírus |
| DE102005047301B4 (de) * | 2005-09-30 | 2009-04-16 | Sartorius Stedim Biotech Gmbh | Verfahren zum Nachweis der Virenabreicherung für die Validierung von Filtern und Filtrationsprozessen |
| US20070084788A1 (en) | 2005-10-14 | 2007-04-19 | Millipore Corporation | Ultrafiltration membranes and methods of making and use of ultrafiltration membranes |
| US8309029B1 (en) * | 2009-03-26 | 2012-11-13 | The United States Of America As Represented By The Secretary Of The Army | Virus and particulate separation from solution |
| US8945895B2 (en) * | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| US9315560B2 (en) * | 2009-08-20 | 2016-04-19 | Baxalta Incorporated | Purification of VWF for increased removal of non-lipid enveloped viruses |
| DK3103861T3 (da) * | 2012-06-21 | 2020-11-16 | Baxalta GmbH | Virusfiltrering af cellekulturmedier |
-
2013
- 2013-06-13 DK DK16181886.9T patent/DK3103861T3/da active
- 2013-06-13 EP EP16181886.9A patent/EP3103861B1/en active Active
- 2013-06-13 SI SI201330369A patent/SI2732020T1/sl unknown
- 2013-06-13 MX MX2014015950A patent/MX347319B/es active IP Right Grant
- 2013-06-13 KR KR1020157001269A patent/KR102008048B1/ko active IP Right Grant
- 2013-06-13 AU AU2013277532A patent/AU2013277532B2/en active Active
- 2013-06-13 SG SG10201701721TA patent/SG10201701721TA/en unknown
- 2013-06-13 BR BR112014031842-5A patent/BR112014031842B1/pt active IP Right Grant
- 2013-06-13 CN CN201810569534.4A patent/CN108795724A/zh active Pending
- 2013-06-13 EA EA201590059A patent/EA033006B1/ru not_active IP Right Cessation
- 2013-06-13 PT PT137310157T patent/PT2732020T/pt unknown
- 2013-06-13 ES ES13731015.7T patent/ES2601429T3/es active Active
- 2013-06-13 CN CN201380032998.7A patent/CN104640969A/zh active Pending
- 2013-06-13 MY MYPI2014003498A patent/MY173835A/en unknown
- 2013-06-13 MY MYPI2018000283A patent/MY195362A/en unknown
- 2013-06-13 NZ NZ629083A patent/NZ629083A/en unknown
- 2013-06-13 PT PT161818869T patent/PT3103861T/pt unknown
- 2013-06-13 CA CA2876473A patent/CA2876473C/en active Active
- 2013-06-13 PL PL13731015T patent/PL2732020T3/pl unknown
- 2013-06-13 IN IN10441DEN2014 patent/IN2014DN10441A/en unknown
- 2013-06-13 JP JP2015518459A patent/JP6220392B2/ja active Active
- 2013-06-13 DK DK13731015.7T patent/DK2732020T3/en active
- 2013-06-13 WO PCT/US2013/045663 patent/WO2013192009A1/en active Application Filing
- 2013-06-13 EP EP13731015.7A patent/EP2732020B1/en active Active
- 2013-06-13 HU HUE13731015A patent/HUE031601T2/hu unknown
- 2013-06-13 KR KR1020197022413A patent/KR20190092618A/ko not_active Application Discontinuation
- 2013-06-13 EA EA201990887A patent/EA201990887A1/ru unknown
- 2013-06-13 PL PL16181886.9T patent/PL3103861T3/pl unknown
- 2013-06-13 SG SG11201408490PA patent/SG11201408490PA/en unknown
- 2013-06-13 ES ES16181886T patent/ES2829968T3/es active Active
- 2013-06-19 AR ARP130102198A patent/AR092847A1/es active IP Right Grant
- 2013-06-19 TW TW106136343A patent/TWI698522B/zh active
- 2013-06-19 TW TW102121710A patent/TWI609962B/zh active
- 2013-06-19 US US13/921,417 patent/US9670456B2/en active Active
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2014
- 2014-11-19 HK HK14111690.4A patent/HK1198335A1/zh unknown
- 2014-12-04 IL IL236073A patent/IL236073B/en active IP Right Grant
- 2014-12-15 ZA ZA2014/09253A patent/ZA201409253B/en unknown
- 2014-12-17 CO CO14277524A patent/CO7151484A2/es unknown
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2016
- 2016-11-02 HR HRP20161435TT patent/HRP20161435T1/hr unknown
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2017
- 2017-03-27 US US15/470,064 patent/US20170260498A1/en not_active Abandoned
- 2017-05-23 HK HK17105198.0A patent/HK1231502A1/zh unknown
- 2017-07-13 JP JP2017137031A patent/JP6557706B2/ja not_active Expired - Fee Related
- 2017-09-12 AU AU2017228547A patent/AU2017228547B2/en active Active
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2018
- 2018-11-14 JP JP2018213613A patent/JP2019022526A/ja not_active Withdrawn
- 2018-12-04 IL IL263479A patent/IL263479B/en active IP Right Grant
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2020
- 2020-03-12 US US16/816,641 patent/US11421202B2/en active Active
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