JP2015529199A - パリペリドンハプテンに対する抗体及びその使用 - Google Patents

パリペリドンハプテンに対する抗体及びその使用 Download PDF

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Publication number
JP2015529199A
JP2015529199A JP2015528574A JP2015528574A JP2015529199A JP 2015529199 A JP2015529199 A JP 2015529199A JP 2015528574 A JP2015528574 A JP 2015528574A JP 2015528574 A JP2015528574 A JP 2015528574A JP 2015529199 A JP2015529199 A JP 2015529199A
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Prior art keywords
paliperidone
antibody
sample
labeled
conjugate
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Pending
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JP2015528574A
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Japanese (ja)
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JP2015529199A5 (cg-RX-API-DMAC7.html
Inventor
リョホレンコ，エリック
サンカラン，バヌマティ
デコリー，トーマス，アール．
タブス，テレサ
コルト，リンダ
ヴリーゲン，マールテン
ハスペスラフ，ピーター，リック
Original Assignee
オルソ−クリニカル ダイアグノスティクス，インコーポレイティド
オルソ−クリニカル ダイアグノスティクス，インコーポレイティド
ヤンセン ファーマシューティカ エヌ．ベー．
ヤンセン ファーマシューティカ エヌ．ベー．
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Application filed by オルソ−クリニカル ダイアグノスティクス，インコーポレイティド, オルソ−クリニカル ダイアグノスティクス，インコーポレイティド, ヤンセン ファーマシューティカ エヌ．ベー．, ヤンセン ファーマシューティカ エヌ．ベー． filed Critical オルソ−クリニカル ダイアグノスティクス，インコーポレイティド
Publication of JP2015529199A publication Critical patent/JP2015529199A/ja
Publication of JP2015529199A5 publication Critical patent/JP2015529199A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2015528574A 2012-08-21 2013-08-20 パリペリドンハプテンに対する抗体及びその使用 Pending JP2015529199A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261691634P 2012-08-21 2012-08-21
US61/691,634 2012-08-21
PCT/US2013/055733 WO2014031603A1 (en) 2012-08-21 2013-08-20 Antibodies to paliperidone haptens and use thereof

Related Child Applications (1)

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JP2018027047A Division JP2018118972A (ja) 2012-08-21 2018-02-19 パリペリドンハプテンに対する抗体及びその使用

Publications (2)

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JP2015529199A true JP2015529199A (ja) 2015-10-05
JP2015529199A5 JP2015529199A5 (cg-RX-API-DMAC7.html) 2018-04-12

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JP2015528574A Pending JP2015529199A (ja) 2012-08-21 2013-08-20 パリペリドンハプテンに対する抗体及びその使用
JP2018027047A Pending JP2018118972A (ja) 2012-08-21 2018-02-19 パリペリドンハプテンに対する抗体及びその使用

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US (4) US20140057297A1 (cg-RX-API-DMAC7.html)
EP (1) EP2888287A4 (cg-RX-API-DMAC7.html)
JP (2) JP2015529199A (cg-RX-API-DMAC7.html)
CN (1) CN104736566A (cg-RX-API-DMAC7.html)
AU (3) AU2013305938B2 (cg-RX-API-DMAC7.html)
CA (1) CA2882489A1 (cg-RX-API-DMAC7.html)
HK (1) HK1211956A1 (cg-RX-API-DMAC7.html)
WO (1) WO2014031603A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018118972A (ja) * 2012-08-21 2018-08-02 ヤンセン ファーマシューティカ エヌ．ベー． パリペリドンハプテンに対する抗体及びその使用

Families Citing this family (15)

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EP2888284B1 (en) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antibodies to risperidone haptens and use thereof
JP6450314B2 (ja) 2012-08-21 2019-01-09 ヤンセン ファーマシューティカ エヌ．ベー． クエチアピンハプテンに対する抗体及びその使用
PL2888592T3 (pl) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
CA2882596C (en) 2012-08-21 2019-05-14 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine and use thereof
WO2014031656A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine haptens and use thereof
CA2882562C (en) 2012-08-21 2019-08-27 Eric Hryhorenko Antibodies to aripiprazole and use thereof
JP6131414B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールのハプテン及びイムノアッセイにおけるそれらの使用
ES2691092T3 (es) 2012-08-21 2018-11-23 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
JP6389176B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールハプテンに対する抗体及びその使用
JP2015527365A (ja) 2012-08-21 2015-09-17 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンに対する抗体及びその使用
EP3390449A1 (en) 2015-12-17 2018-10-24 Janssen Pharmaceutica N.V. Antibodies to risperidone and use thereof
US10435478B2 (en) 2015-12-17 2019-10-08 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN107137715B (zh) * 2017-04-26 2019-02-19 石家庄蒎格医药科技有限公司 一种帕利哌酮聚乙二醇缀合前药及制备
CN112608310B (zh) * 2020-12-17 2022-03-29 北京丹大生物技术有限公司 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用
CN112730825B (zh) * 2020-12-17 2022-09-06 北京丹大生物技术有限公司 一种用于检测利培酮和/或9-羟基利培酮的检测试剂和检测试剂盒

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