JP2015523074A5 - - Google Patents

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Publication number
JP2015523074A5
JP2015523074A5 JP2015520577A JP2015520577A JP2015523074A5 JP 2015523074 A5 JP2015523074 A5 JP 2015523074A5 JP 2015520577 A JP2015520577 A JP 2015520577A JP 2015520577 A JP2015520577 A JP 2015520577A JP 2015523074 A5 JP2015523074 A5 JP 2015523074A5
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JP
Japan
Prior art keywords
protein
recombinant
item
optionally
seq
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015520577A
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English (en)
Japanese (ja)
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JP2015523074A (ja
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Publication date
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Priority claimed from PCT/US2013/048601 external-priority patent/WO2014005036A1/en
Publication of JP2015523074A publication Critical patent/JP2015523074A/ja
Publication of JP2015523074A5 publication Critical patent/JP2015523074A5/ja
Pending legal-status Critical Current

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JP2015520577A 2012-06-29 2013-06-28 組換えイズロン酸2スルファターゼの製造方法 Pending JP2015523074A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261666712P 2012-06-29 2012-06-29
US61/666,712 2012-06-29
PCT/US2013/048601 WO2014005036A1 (en) 2012-06-29 2013-06-28 Method of producing recombinant iduronate-2-sulfatase

Publications (2)

Publication Number Publication Date
JP2015523074A JP2015523074A (ja) 2015-08-13
JP2015523074A5 true JP2015523074A5 (enExample) 2016-08-12

Family

ID=49778402

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015520577A Pending JP2015523074A (ja) 2012-06-29 2013-06-28 組換えイズロン酸2スルファターゼの製造方法

Country Status (21)

Country Link
US (1) US20140004097A1 (enExample)
EP (1) EP2867367A4 (enExample)
JP (1) JP2015523074A (enExample)
KR (1) KR20150037908A (enExample)
CN (1) CN104583414A (enExample)
AU (1) AU2013282417A1 (enExample)
BR (1) BR112014032544A2 (enExample)
CA (1) CA2877492A1 (enExample)
CL (1) CL2014003569A1 (enExample)
CO (1) CO7240395A2 (enExample)
CR (1) CR20140587A (enExample)
DO (1) DOP2014000297A (enExample)
EA (1) EA201492185A1 (enExample)
HK (2) HK1209790A1 (enExample)
IL (1) IL236324A0 (enExample)
IN (1) IN2014DN11272A (enExample)
MX (1) MX2015000188A (enExample)
PE (1) PE20150603A1 (enExample)
PH (1) PH12014502870A1 (enExample)
SG (1) SG11201408755TA (enExample)
WO (1) WO2014005036A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
KR101380740B1 (ko) 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
CA3140358A1 (en) 2012-07-31 2014-02-06 Bioasis Technologies, Inc. Dephosphorylated lysosomal storage disease proteins and methods of use thereof
WO2014160438A1 (en) 2013-03-13 2014-10-02 Bioasis Technologies Inc. Fragments of p97 and uses thereof
CA2935805C (en) * 2014-02-19 2023-07-11 Bioasis Technologies, Inc. P97-ids fusion proteins
CN107250372B (zh) * 2015-02-05 2022-11-01 R.P.谢勒技术有限责任公司 活化的甲酰甘氨酸生成酶及其生成和使用方法
CA3118834C (en) * 2015-10-07 2024-06-11 Joel HUIZENGA Resetting biological pathways for defending against and repairing deterioration from human aging
CA3004584A1 (en) 2015-11-09 2017-05-18 R.P. Scherer Technologies, Llc Anti-cd22 antibody-maytansine conjugates and methods of use thereof
AU2017301691B2 (en) * 2016-07-25 2022-07-21 Repligen Corporation Alternating tangential flow rapid harvesting
JP2021500857A (ja) 2017-10-02 2021-01-14 デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. 酵素補充療法用酵素を含む融合タンパク質

Family Cites Families (14)

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EP2221361A3 (en) 1996-08-30 2011-02-09 Life Technologies Corporation Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium
IL145893A0 (en) * 1999-04-26 2002-07-25 Genentech Inc Cell culture process for glycoproteins
US6890736B1 (en) * 2002-09-20 2005-05-10 Immunex Corporation Methods for producing proteins in cultured cells
CN101444621B (zh) * 2003-02-11 2013-11-20 夏尔人类遗传性治疗公司 使用甲酰-甘氨酸生成酶(fge)对多种硫酸酯酶缺乏症和其它病症进行诊断和治疗
US20050019914A1 (en) * 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
WO2005113765A2 (en) 2004-05-06 2005-12-01 Biomarin Pharmaceutical Inc. Methods of activation of sulfatases and methods and compositions of using the same
ES2370417T3 (es) * 2005-06-03 2011-12-15 Ares Trading S.A. Producción de una proteína de unión a il-18 recombinante.
AU2006322028C1 (en) * 2005-12-08 2025-09-04 Amgen Inc. Improved host cells and culture methods
SI3219795T1 (sl) 2008-01-18 2024-10-30 Biomarin Pharmaceutical Inc. Izdelava akitvnih visoko fosforiliranih humanih encimov lizomske sulfataze in njihova uporaba
PL2485761T3 (pl) * 2009-10-09 2019-10-31 Armagen Inc Sposoby i kompozycje do zwiększania aktywności 2-sulfatazy iduronianu w cns
US20130196410A1 (en) * 2010-03-05 2013-08-01 Alnylam Pharmaceuticals, Inc Compositions and methods for modifying the glycosylation pattern of a polypeptide
ES2754234T3 (es) 2010-06-25 2020-04-16 Shire Human Genetic Therapies Métodos y composiciones para la administración SNC de iduronato-2-sulfatasa
KR101158673B1 (ko) * 2011-06-24 2012-07-03 주식회사 지씨바이오 재조합 인간 이듀로네이트-2-설파타아제를 포함하는 조성물, 제제 및 이의 제조방법
US9150841B2 (en) * 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase

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