JP2015521050A5 - - Google Patents

Download PDF

Info

Publication number
JP2015521050A5
JP2015521050A5 JP2015515598A JP2015515598A JP2015521050A5 JP 2015521050 A5 JP2015521050 A5 JP 2015521050A5 JP 2015515598 A JP2015515598 A JP 2015515598A JP 2015515598 A JP2015515598 A JP 2015515598A JP 2015521050 A5 JP2015521050 A5 JP 2015521050A5
Authority
JP
Japan
Prior art keywords
maf
subject
expression level
copy number
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015515598A
Other languages
English (en)
Japanese (ja)
Other versions
JP6386450B2 (ja
JP2015521050A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2013/001859 external-priority patent/WO2013182912A2/en
Publication of JP2015521050A publication Critical patent/JP2015521050A/ja
Publication of JP2015521050A5 publication Critical patent/JP2015521050A5/ja
Application granted granted Critical
Publication of JP6386450B2 publication Critical patent/JP6386450B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015515598A 2012-06-06 2013-06-06 肺がん転移の診断、予後診断および処置のための方法 Active JP6386450B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261656372P 2012-06-06 2012-06-06
US61/656,372 2012-06-06
PCT/IB2013/001859 WO2013182912A2 (en) 2012-06-06 2013-06-06 Method for the diagnosis, prognosis and treatment of lung cancer metastasis

Publications (3)

Publication Number Publication Date
JP2015521050A JP2015521050A (ja) 2015-07-27
JP2015521050A5 true JP2015521050A5 (enExample) 2016-08-04
JP6386450B2 JP6386450B2 (ja) 2018-09-05

Family

ID=49237517

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015515598A Active JP6386450B2 (ja) 2012-06-06 2013-06-06 肺がん転移の診断、予後診断および処置のための方法

Country Status (13)

Country Link
US (2) US10006091B2 (enExample)
EP (2) EP3467124A1 (enExample)
JP (1) JP6386450B2 (enExample)
KR (1) KR102226219B1 (enExample)
CN (1) CN104603288B (enExample)
AU (2) AU2013273242B2 (enExample)
BR (1) BR112014030750A2 (enExample)
CA (1) CA2875918A1 (enExample)
DK (1) DK2859120T3 (enExample)
ES (1) ES2705237T3 (enExample)
MX (1) MX368513B (enExample)
TR (1) TR201819859T4 (enExample)
WO (1) WO2013182912A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3091085T3 (da) 2010-10-06 2019-05-06 Inst Catalana Recerca Estudis Avancats Fremgangsmåde til at designe en terapi mod brystcancermetastase
EP2650682A1 (en) 2012-04-09 2013-10-16 Fundació Privada Institut de Recerca Biomèdica Method for the prognosis and treatment of cancer metastasis
EP3467124A1 (en) 2012-06-06 2019-04-10 Fundació Institut de Recerca Biomèdica IRB (Barcelona) Method for the diagnosis, prognosis and treatment of lung cancer metastasis
US10119171B2 (en) 2012-10-12 2018-11-06 Inbiomotion S.L. Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
JP6074049B2 (ja) * 2012-10-12 2017-02-01 インバイオモーション エセ.エレ. c−MAFを用いた前立腺がん転移の診断、予後診断および処置のための方法
US20160032399A1 (en) * 2013-03-15 2016-02-04 Inbiomotion S.L. Method for the Prognosis and Treatment of Renal Cell Carcinoma Metastasis
US20160040247A1 (en) 2013-03-15 2016-02-11 Fundació Institut De Recerca Biomèdica (Irb Barcelona) Method for the diagnosis, prognosis, and tratment of cancer metastasis
AU2014229505B2 (en) * 2013-03-15 2020-02-27 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the prognosis and treatment of cancer metastasis
CA2987389A1 (en) 2014-06-02 2015-12-10 Valley Health System Method and systems for lung cancer diagnosis
CN104398506A (zh) * 2014-12-09 2015-03-11 厦门大学 雷奈酸锶在制备预防和治疗腺癌药物中的新用途
KR20170093182A (ko) * 2014-12-11 2017-08-14 인바이오모션 에스.엘. 인간 c-maf에 대한 결합 구성원
CN107921082A (zh) 2015-03-12 2018-04-17 莫伊莱麦屈克斯公司 含有mk2抑制剂肽的组合物用于治疗非小细胞肺癌的用途
WO2016205334A1 (en) 2015-06-16 2016-12-22 Vascular Strategies Llc Drug delivery and imaging chemical conjugate, formulations and methods of use thereof
CN105154542B (zh) * 2015-09-01 2018-04-17 杭州源清生物科技有限公司 一组用于肺癌分子分型的基因及其应用
KR20180111870A (ko) 2016-02-25 2018-10-11 셀 메디카 스위처란트 아게 Pd-l1에 대한 결합 성분
SG11201810082VA (en) * 2016-05-13 2018-12-28 Golden Biotechnology Corp Methods and compositions for treating advanced stage non-small cell lung cancer
WO2017201043A1 (en) * 2016-05-16 2017-11-23 Concert Pharmaceuticals, Inc. Combination therapy for treating cancer
PT3458610T (pt) 2016-05-25 2021-06-29 Inbiomotion Sl Tratamento terapêutico de cancro da mama baseado no estado de c-maf
CN106055921A (zh) * 2016-05-27 2016-10-26 华中农业大学 基于基因表达和药物靶标的药物活性预测与筛选方法
CN106119405B (zh) * 2016-08-31 2019-11-12 广州万德基因医学科技有限公司 一种肺癌的预后标记物、使用该标记预测肺癌预后的方法及应用
CN107058480B (zh) * 2016-12-14 2018-07-13 河北医科大学第四医院(河北省肿瘤医院) 用于诊断肺腺癌的长链非编码rna标志物
CN106815486B (zh) * 2017-01-22 2021-06-04 华中农业大学 一种个性化用药的系统药理学方法
CN107058499B (zh) * 2017-01-25 2020-03-13 河北医科大学第四医院(河北省肿瘤医院) 一种用于肺腺癌诊治的分子标志物
WO2019102380A1 (en) 2017-11-22 2019-05-31 Inbiomotion S.L. Therapeutic treatment of breast cancer based on c-maf
WO2019152788A1 (en) 2018-02-02 2019-08-08 Morgan And Mendel Genomics, Inc. Robust genomic predictor of breast and lung cancer metastasis
KR102218199B1 (ko) 2019-01-31 2021-02-22 중앙대학교 산학협력단 폐암 전이 예측용 바이오마커 조성물
CN110157792A (zh) * 2019-04-22 2019-08-23 中山大学孙逸仙纪念医院 血清外泌体has_circ_0004771在制备酒精依赖综合征诊断试剂中的应用
CN110093422A (zh) * 2019-05-24 2019-08-06 中国人民解放军西部战区总医院 Linc02159在肺腺癌诊疗中的应用
KR102260915B1 (ko) * 2020-02-19 2021-06-04 한국원자력의학원 폐암의 방사선 치료 예후 예측을 위한 생체 표지자
CN119143798B (zh) * 2024-08-01 2025-09-30 河北医科大学 一种骨靶向阿仑膦酸-普萘洛尔及其制备方法与应用
CN119876392B (zh) * 2025-01-06 2025-08-12 上海市第六人民医院 一种用于辅助诊断肺腺癌骨转移的生物标志物

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE89314T1 (de) 1985-02-13 1993-05-15 Scios Nova Inc Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen.
US4902505A (en) 1986-07-30 1990-02-20 Alkermes Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
US5176996A (en) 1988-12-20 1993-01-05 Baylor College Of Medicine Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
US5256775A (en) 1989-06-05 1993-10-26 Gilead Sciences, Inc. Exonuclease-resistant oligonucleotides
US5264564A (en) 1989-10-24 1993-11-23 Gilead Sciences Oligonucleotide analogs with novel linkages
AU734051B2 (en) 1996-04-05 2001-05-31 Salk Institute For Biological Studies, The Hormone-mediated methods for modulating expression of exogenous genes in mammalian systems, and products related thereto
EP2003203A1 (en) 1996-12-23 2008-12-17 Immunex Corporation Ligand for receptor activator of nf-kappa b, ligand is member of TNF superfamily
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
US6274338B1 (en) 1998-02-24 2001-08-14 President And Fellows Of Harvard College Human c-Maf compositions and methods of use thereof
EP1161415B1 (en) 1999-03-15 2005-07-13 Axys Pharmaceuticals, Inc. N-cyanomethylamides as protease inhibitors
TW404030B (en) 1999-04-12 2000-09-01 Siliconware Precision Industries Co Ltd Dual-chip semiconductor package device having malposition and the manufacture method thereof
US6287813B1 (en) 1999-04-23 2001-09-11 Cistronics Cell Technology Gmbh Antibiotic-based gene regulation system
US6525036B2 (en) 2000-01-06 2003-02-25 Merck & Co., Inc. Compounds and compositions as protease inhibitors
EP1356093A2 (en) 2000-06-21 2003-10-29 Hitachi Chemical Co., Ltd. Gene markers for lung cancer
US6750015B2 (en) 2000-06-28 2004-06-15 Kathryn B. Horwitz Progesterone receptor-regulated gene expression and methods related thereto
MY143582A (en) 2001-06-26 2011-05-31 Amgent Fremont Inc Antibodies to opgl
AR036375A1 (es) 2001-08-30 2004-09-01 Novartis Ag Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
GB0121033D0 (en) 2001-08-30 2001-10-24 Novartis Ag Organic compounds
KR100485271B1 (ko) 2002-01-16 2005-04-27 메타볼랩(주) 전사인자 c-maf의 전사 활성 억제제로서의 니발레놀및 그를 포함하는 약제학적 조성물
SE0201980D0 (sv) 2002-06-24 2002-06-24 Astrazeneca Ab Novel compounds
DE10235624A1 (de) 2002-08-02 2004-02-19 Aventis Pharma Deutschland Gmbh Endiandric acid H und ihre Derivate, Verfahren zu ihrer Herstellung und Verwendung derselben
WO2005026322A2 (en) 2003-09-11 2005-03-24 Clontech Laboratories, Inc. siRNA ENCODING CONSTRUCTS AND METHODS FOR USING THE SAME
AU2003286499A1 (en) 2003-10-17 2004-06-06 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Interference with c-maf function in multiple myeloma
WO2005060722A2 (en) 2003-12-18 2005-07-07 President And Fellows Of Hardvard College Modulation of immune system function by modulation of polypeptide arginine methyltransferases
TW200526224A (en) 2003-12-22 2005-08-16 Alcon Inc Short form c-Maf transcription factor antagonists for treatment of glaucoma
WO2005086891A2 (en) * 2004-03-05 2005-09-22 Rosetta Inpharmatics Llc Classification of breast cancer patients using a combination of clinical criteria and informative genesets
WO2006012221A2 (en) 2004-06-25 2006-02-02 The Regents Of The University Of California Target cell-specific short interfering rna and methods of use thereof
WO2006135436A2 (en) 2004-10-22 2006-12-21 University Of Florida Research Foundation, Inc. Inhibition of gene expression and therapeutic uses thereof
US9134237B2 (en) 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
WO2007053245A2 (en) 2005-09-20 2007-05-10 Immunivest Corporation Methods and composition to generate unique sequence dna probes, iabeling of dna probes and the use of these probes
EP1931994A2 (en) * 2005-09-26 2008-06-18 Novartis AG Molecular markers associated with bone metastasis
CA2632451C (en) 2005-12-06 2015-11-03 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
WO2008098351A1 (en) 2007-02-14 2008-08-21 University Health Network Treatment of d-cyclin mediated proliferative diseases and hemotological malignancies
EP1961825A1 (en) 2007-02-26 2008-08-27 INSERM (Institut National de la Santé et de la Recherche Medicale) Method for predicting the occurrence of metastasis in breast cancer patients
JP2010527914A (ja) * 2007-04-26 2010-08-19 クォーク ファーマシューティカルズ インコーポレーティッド 呼吸器系への抑制性核酸分子の治療的送達
AU2008252853B2 (en) 2007-05-24 2011-12-01 Ablynx N.V. Amino acid sequences directed against RANK-L and polypeptides comprising the same for the treatment of bone diseases and disorders
AU2008314459A1 (en) 2007-10-18 2009-04-23 University Health Network Clioquinol for the treatment of hematological malignancies
CA2726537A1 (en) 2008-06-06 2009-12-10 University Health Network 8-hydroxyquinoline derivatives for the treatment of hematological malignancies
CA2729521A1 (en) * 2008-07-02 2010-01-07 Assistance Publique Hopitaux De Paris A method for predicting clinical outcome of patients with non-small cell lung carcinoma
DK3091085T3 (da) 2010-10-06 2019-05-06 Inst Catalana Recerca Estudis Avancats Fremgangsmåde til at designe en terapi mod brystcancermetastase
US20140162887A1 (en) 2011-02-04 2014-06-12 Bioarray Therapeutics, Inc. Methods of using gene expression signatures to select a method of treatment, predict prognosis, survival, and/or predict response to treatment
EP2650682A1 (en) 2012-04-09 2013-10-16 Fundació Privada Institut de Recerca Biomèdica Method for the prognosis and treatment of cancer metastasis
EP3467124A1 (en) 2012-06-06 2019-04-10 Fundació Institut de Recerca Biomèdica IRB (Barcelona) Method for the diagnosis, prognosis and treatment of lung cancer metastasis
US10119171B2 (en) 2012-10-12 2018-11-06 Inbiomotion S.L. Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
JP6074049B2 (ja) 2012-10-12 2017-02-01 インバイオモーション エセ.エレ. c−MAFを用いた前立腺がん転移の診断、予後診断および処置のための方法
AU2014229505B2 (en) 2013-03-15 2020-02-27 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the prognosis and treatment of cancer metastasis
US20160040247A1 (en) 2013-03-15 2016-02-11 Fundació Institut De Recerca Biomèdica (Irb Barcelona) Method for the diagnosis, prognosis, and tratment of cancer metastasis
US20160032399A1 (en) 2013-03-15 2016-02-04 Inbiomotion S.L. Method for the Prognosis and Treatment of Renal Cell Carcinoma Metastasis
JP6550045B2 (ja) 2013-10-09 2019-07-24 フンダシオ、インスティトゥト、デ、レセルカ、ビオメディカ(イエレベ、バルセロナ)Fundacio Institut De Recerca Biomedica (Irb Barcelona) 乳がんに由来する骨の転移がんの予後診断および処置のための方法
US11129851B2 (en) 2014-06-17 2021-09-28 Igenomix S.L. Stem cell therapy in endometrial pathologies
KR20170093182A (ko) 2014-12-11 2017-08-14 인바이오모션 에스.엘. 인간 c-maf에 대한 결합 구성원
PT3458610T (pt) 2016-05-25 2021-06-29 Inbiomotion Sl Tratamento terapêutico de cancro da mama baseado no estado de c-maf
WO2019102380A1 (en) 2017-11-22 2019-05-31 Inbiomotion S.L. Therapeutic treatment of breast cancer based on c-maf

Similar Documents

Publication Publication Date Title
JP2015521050A5 (enExample)
Meng et al. Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
JP2016516403A5 (enExample)
Thomas et al. Expression profiling of cervical cancers in I ndian women at different stages to identify gene signatures during progression of the disease
Han et al. MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1
JP2015520606A5 (enExample)
Pichler et al. miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor
WO2013182912A4 (en) Method for the diagnosis, prognosis and treatment of lung cancer metastasis
Shames et al. High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck
JP2016105731A5 (enExample)
JP5690588B2 (ja) 肝細胞癌のサブタイプを決定し、肝癌幹細胞を検出するための方法
Al-Khanbashi et al. Tissue and serum miRNA profile in locally advanced breast cancer (LABC) in response to neo-adjuvant chemotherapy (NAC) treatment
Hung et al. Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma
Cui et al. LncRNA FAM230B promotes gastric cancer growth and metastasis by regulating the miR-27a-5p/TOP2A axis
JP2013541339A5 (enExample)
JP6039656B2 (ja) 癌再発の予後予測のための方法および装置
JP2018078911A5 (enExample)
ES2748005T3 (es) Método para predecir la respuesta a agentes terapéuticos de cáncer de mama y método de tratamiento de cáncer de mama
JP2019523641A5 (enExample)
JP2010535473A5 (enExample)
JP2012522756A5 (enExample)
JP6931926B2 (ja) 遺伝子発現プロファイル及び乳癌におけるその使用
Davidson et al. Gene expression signatures differentiate adenocarcinoma of lung and breast origin in effusions
JP2014533960A5 (enExample)
WO2010101916A1 (en) Methods for predicting cancer response to egfr inhibitors