JP2008536480A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008536480A5 JP2008536480A5 JP2007556309A JP2007556309A JP2008536480A5 JP 2008536480 A5 JP2008536480 A5 JP 2008536480A5 JP 2007556309 A JP2007556309 A JP 2007556309A JP 2007556309 A JP2007556309 A JP 2007556309A JP 2008536480 A5 JP2008536480 A5 JP 2008536480A5
- Authority
- JP
- Japan
- Prior art keywords
- marker
- cancer
- subject
- sample
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003550 marker Substances 0.000 claims 45
- 206010028980 Neoplasm Diseases 0.000 claims 36
- 201000011510 cancer Diseases 0.000 claims 36
- 239000000523 sample Substances 0.000 claims 28
- 238000000034 method Methods 0.000 claims 27
- 230000000694 effects Effects 0.000 claims 23
- 108090000623 proteins and genes Proteins 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 6
- 230000002401 inhibitory effect Effects 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 238000002560 therapeutic procedure Methods 0.000 claims 3
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 238000012228 RNA interference-mediated gene silencing Methods 0.000 claims 2
- 238000010171 animal model Methods 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000009368 gene silencing by RNA Effects 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 238000003753 real-time PCR Methods 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 102100026596 Bcl-2-like protein 1 Human genes 0.000 claims 1
- 101150008012 Bcl2l1 gene Proteins 0.000 claims 1
- 101000830894 Homo sapiens Targeting protein for Xklp2 Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000003979 Mineralocorticoid Receptors Human genes 0.000 claims 1
- 108090000375 Mineralocorticoid Receptors Proteins 0.000 claims 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 108091027967 Small hairpin RNA Proteins 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 102100024813 Targeting protein for Xklp2 Human genes 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000000074 antisense oligonucleotide Substances 0.000 claims 1
- 238000012230 antisense oligonucleotides Methods 0.000 claims 1
- 108700000711 bcl-X Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 230000000052 comparative effect Effects 0.000 claims 1
- -1 comparing Chemical class 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000007901 in situ hybridization Methods 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 238000006452 multicomponent reaction Methods 0.000 claims 1
- 239000002853 nucleic acid probe Substances 0.000 claims 1
- 239000000816 peptidomimetic Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000004055 small Interfering RNA Substances 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65422705P | 2005-02-17 | 2005-02-17 | |
| US69006405P | 2005-06-13 | 2005-06-13 | |
| PCT/US2006/005584 WO2006089087A2 (en) | 2005-02-17 | 2006-02-17 | Compositions, kits and methods for identification, assessment, prevention and therapy of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008536480A JP2008536480A (ja) | 2008-09-11 |
| JP2008536480A5 true JP2008536480A5 (enExample) | 2009-03-26 |
Family
ID=36917075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007556309A Pending JP2008536480A (ja) | 2005-02-17 | 2006-02-17 | 癌の同定、評価、予防、および治療用組成物、キット、および方法、ならびに癌の治療法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8168602B2 (enExample) |
| EP (1) | EP1855727A2 (enExample) |
| JP (1) | JP2008536480A (enExample) |
| CA (1) | CA2595699A1 (enExample) |
| WO (1) | WO2006089087A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2642342A1 (en) | 2006-02-14 | 2007-08-23 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
| WO2008016996A2 (en) * | 2006-08-01 | 2008-02-07 | Joslin Diabetes Center, Inc. | Methods of modulating metabolic memory |
| JP2010503407A (ja) * | 2006-09-12 | 2010-02-04 | ジェネンテック・インコーポレーテッド | 癌の診断及び治療のための方法及び組成物 |
| WO2008144724A1 (en) * | 2007-05-21 | 2008-11-27 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
| US20090075266A1 (en) * | 2007-09-14 | 2009-03-19 | Predictive Biosciences Corporation | Multiple analyte diagnostic readout |
| JP2011001267A (ja) * | 2007-10-17 | 2011-01-06 | Univ Of Tokyo | 大腸癌治療薬 |
| JP5586164B2 (ja) * | 2009-04-06 | 2014-09-10 | 聡明 渡邉 | 潰瘍性大腸炎患者の癌化リスクを決定する方法 |
| WO2010121370A1 (en) * | 2009-04-20 | 2010-10-28 | University Health Network | Prognostic gene expression signature for squamous cell carcinoma of the lung |
| CA2789494C (en) * | 2010-02-10 | 2021-08-17 | The Regents Of The University Of California | Salivary biomarkers for lung cancer detection |
| EP2913405B1 (en) | 2010-07-27 | 2016-11-09 | Genomic Health, Inc. | Method for using gene expression to determine prognosis of prostate cancer |
| US8709718B1 (en) | 2011-02-12 | 2014-04-29 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Method of treating lung cancer |
| PL2768985T3 (pl) * | 2011-10-21 | 2019-10-31 | Chronix Biomedical | Biomarkery będące krążącymi kwasami nukleinowymi związane z rakiem jelita grubego |
| EP3544015B1 (en) | 2012-02-03 | 2024-10-23 | California Institute of Technology | Signal encoding and decoding in multiplexed biochemical assays |
| CN109979526B (zh) * | 2014-03-25 | 2023-11-24 | 凡弗3基因组有限公司 | 用于功能证实癌症突变的rna分析的系统和方法 |
| GB201521894D0 (en) | 2015-12-11 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various cancers |
| HK1255541A1 (zh) | 2015-12-11 | 2019-08-23 | Immatics Biotechnologies Gmbh | 用於多种癌症免疫治疗的新型肽和肽组合物 |
| EP3405185A4 (en) * | 2016-01-19 | 2019-09-18 | Thomas Blumenthal | BIOMARKERS FOR DOWN SYNDROME AND USES THEREOF |
| EP3203413A1 (en) * | 2016-02-08 | 2017-08-09 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for quantitative measurement of a biomarker by in situ immunofluorescence and uses thereof |
| KR102775704B1 (ko) | 2017-08-07 | 2025-02-28 | 더 존스 홉킨스 유니버시티 | 암을 평가하고 치료하기 위한 방법 및 재료 |
| CN109125729A (zh) * | 2018-09-06 | 2019-01-04 | 苏州吉玛基因股份有限公司 | 与非小细胞肺癌诊疗相关的基因BRD9及其siRNAs和应用 |
| JP7262736B2 (ja) * | 2018-10-31 | 2023-04-24 | 公立大学法人北九州市立大学 | 癌の診断を補助する方法、および癌を診断するシステム |
| JP7577337B2 (ja) * | 2019-07-24 | 2024-11-05 | 国立大学法人東北大学 | キメラ分子、医薬組成物、標的核酸の切断方法、及び、標的核酸切断用又は診断用キット |
| CN110317876A (zh) * | 2019-08-02 | 2019-10-11 | 苏州宏元生物科技有限公司 | 一组染色体不稳定变异在制备诊断多发性骨髓瘤、评估预后的试剂或试剂盒中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6602713B1 (en) * | 2001-02-09 | 2003-08-05 | Isis Pharmaceuticals, Inc. | Antisense modulation of protein phosphatase 2 catalytic subunit beta expression |
| US5783683A (en) * | 1995-01-10 | 1998-07-21 | Genta Inc. | Antisense oligonucleotides which reduce expression of the FGFRI gene |
| JP4658936B2 (ja) * | 2004-03-24 | 2011-03-23 | オンコセラピー・サイエンス株式会社 | 肺癌を治療するための組成物および方法 |
| CA2568413A1 (en) * | 2004-05-28 | 2005-12-15 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
-
2006
- 2006-02-17 WO PCT/US2006/005584 patent/WO2006089087A2/en not_active Ceased
- 2006-02-17 CA CA002595699A patent/CA2595699A1/en not_active Abandoned
- 2006-02-17 JP JP2007556309A patent/JP2008536480A/ja active Pending
- 2006-02-17 US US11/816,601 patent/US8168602B2/en not_active Expired - Fee Related
- 2006-02-17 EP EP06735309A patent/EP1855727A2/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008536480A5 (enExample) | ||
| US20200232045A1 (en) | Methods of identifying individuals at increased risk of lung cancer | |
| Barker et al. | Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis | |
| JP6148007B2 (ja) | 前立腺癌マーカーとしてのホスホジエステラーゼ４ｄ７ | |
| JP2023118802A (ja) | 非アルコール性脂肪性肝疾患、非アルコール性脂肪性肝炎、及び／又は肝線維症の非侵襲的診断 | |
| JP2015521050A5 (enExample) | ||
| JP6755242B2 (ja) | 新規分子バイオマーカーを使用して慢性閉塞性肺疾患（ｃｏｐｄ）を診断する方法 | |
| JP2008512984A5 (enExample) | ||
| CN101861400A (zh) | 患者的基于基因的算法型癌症预后和临床结果 | |
| JP2013541339A5 (enExample) | ||
| US20220136061A1 (en) | Treatment and detection of melanoma | |
| JP2008537474A5 (enExample) | ||
| JP2017519522A (ja) | 新規分子バイオマーカーを使用して慢性閉塞性肺疾患（ｃｏｐｄ）を診断する方法 | |
| WO2016089732A2 (en) | Methods and compositions for diagnosis and management of diabetes and metabolic syndrome | |
| WO2017039359A1 (ko) | 트립토파닐 티알엔에이 합성효소를 이용한 감염 질환 또는 감염 합병증의 진단용 조성물과 진단 마커 검출 방법 | |
| KR101925125B1 (ko) | Nckap1을 유효성분으로 포함하는 대장암 진단 또는 대장암 전이 예후 예측용 바이오마커 조성물 | |
| JP2018504909A5 (enExample) | ||
| JP2008514209A (ja) | 癌マーカー | |
| CN110016504A (zh) | CDR1as在神经管畸形产前筛查中的应用、神经管畸形产前筛查的产品和方法 | |
| JP2012526543A5 (enExample) | ||
| EP2710143A1 (en) | Method for determining whether a subject is at risk of having or developing a chronic kidney disease | |
| US20250327805A1 (en) | Enigma and cdh18 as companion diagnostics for cdk4 inhibitors | |
| JP2008547006A5 (enExample) | ||
| KR20220039065A (ko) | 대장암에 대한 항암제 감수성 예측을 위한 신규 바이오마커 | |
| JP7610265B2 (ja) | 大腸癌診断用マーカー、大腸癌の診断を補助する方法、大腸癌の診断のためにデータを収集する方法、大腸癌の診断用キット、大腸癌治療薬、大腸癌の治療方法、大腸癌の診断方法 |