JP2019523641A5 - - Google Patents
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- JP2019523641A5 JP2019523641A5 JP2018561228A JP2018561228A JP2019523641A5 JP 2019523641 A5 JP2019523641 A5 JP 2019523641A5 JP 2018561228 A JP2018561228 A JP 2018561228A JP 2018561228 A JP2018561228 A JP 2018561228A JP 2019523641 A5 JP2019523641 A5 JP 2019523641A5
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- 238000000034 method Methods 0.000 claims description 116
- 230000014509 gene expression Effects 0.000 claims description 74
- 102100039189 Transcription factor Maf Human genes 0.000 claims description 73
- 230000003321 amplification Effects 0.000 claims description 71
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 71
- 108090000623 proteins and genes Proteins 0.000 claims description 41
- 239000000523 sample Substances 0.000 claims description 40
- 230000004083 survival effect Effects 0.000 claims description 37
- 206010006187 Breast cancer Diseases 0.000 claims description 36
- 208000026310 Breast neoplasm Diseases 0.000 claims description 36
- 238000007901 in situ hybridization Methods 0.000 claims description 24
- 201000010099 disease Diseases 0.000 claims description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 19
- 108020004635 Complementary DNA Proteins 0.000 claims description 18
- 238000010804 cDNA synthesis Methods 0.000 claims description 18
- 239000002299 complementary DNA Substances 0.000 claims description 18
- 108020004999 messenger RNA Proteins 0.000 claims description 18
- 238000000338 in vitro Methods 0.000 claims description 17
- 230000010072 bone remodeling Effects 0.000 claims description 13
- 239000012634 fragment Substances 0.000 claims description 12
- 102000004169 proteins and genes Human genes 0.000 claims description 12
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 claims description 11
- 229960004276 zoledronic acid Drugs 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 10
- 239000013068 control sample Substances 0.000 claims description 9
- 206010028980 Neoplasm Diseases 0.000 claims description 6
- 238000003752 polymerase chain reaction Methods 0.000 claims description 6
- 210000000988 bone and bone Anatomy 0.000 claims description 5
- 238000011002 quantification Methods 0.000 claims description 5
- 206010027476 Metastases Diseases 0.000 claims description 4
- 229910052709 silver Inorganic materials 0.000 claims description 4
- 239000004332 silver Substances 0.000 claims description 4
- 206010027452 Metastases to bone Diseases 0.000 claims description 3
- 208000003721 Triple Negative Breast Neoplasms Diseases 0.000 claims description 3
- 201000007280 estrogen-receptor negative breast cancer Diseases 0.000 claims description 3
- 208000022679 triple-negative breast carcinoma Diseases 0.000 claims description 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 2
- 108020004414 DNA Proteins 0.000 claims description 2
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- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims description 2
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- 201000007281 estrogen-receptor positive breast cancer Diseases 0.000 claims description 2
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- MPBVHIBUJCELCL-UHFFFAOYSA-N Ibandronate Chemical compound CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O MPBVHIBUJCELCL-UHFFFAOYSA-N 0.000 claims 7
- 229960002286 clodronic acid Drugs 0.000 claims 7
- ACSIXWWBWUQEHA-UHFFFAOYSA-N clodronic acid Chemical compound OP(O)(=O)C(Cl)(Cl)P(O)(O)=O ACSIXWWBWUQEHA-UHFFFAOYSA-N 0.000 claims 7
- 229940015872 ibandronate Drugs 0.000 claims 7
- 210000000481 breast Anatomy 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 description 14
- 102000014128 RANK Ligand Human genes 0.000 description 13
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- 229940091171 VEGFR-2 tyrosine kinase inhibitor Drugs 0.000 description 5
- 150000004663 bisphosphonates Chemical class 0.000 description 5
- 230000009977 dual effect Effects 0.000 description 5
- 229940124302 mTOR inhibitor Drugs 0.000 description 4
- 239000003628 mammalian target of rapamycin inhibitor Substances 0.000 description 4
- 229940124297 CDK 4/6 inhibitor Drugs 0.000 description 3
- 102000055006 Calcitonin Human genes 0.000 description 3
- 108060001064 Calcitonin Proteins 0.000 description 3
- 102100030074 Dickkopf-related protein 1 Human genes 0.000 description 3
- 101710099518 Dickkopf-related protein 1 Proteins 0.000 description 3
- 108090000445 Parathyroid hormone Proteins 0.000 description 3
- 102000001332 SRC Human genes 0.000 description 3
- 229960004015 calcitonin Drugs 0.000 description 3
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 3
- 229940111134 coxibs Drugs 0.000 description 3
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 description 3
- 238000001794 hormone therapy Methods 0.000 description 3
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- 239000003757 phosphotransferase inhibitor Substances 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- HCWPIIXVSYCSAN-OIOBTWANSA-N radium-223 Chemical compound [223Ra] HCWPIIXVSYCSAN-OIOBTWANSA-N 0.000 description 3
- 229960005562 radium-223 Drugs 0.000 description 3
- 108010087686 src-Family Kinases Proteins 0.000 description 3
- 229940079488 strontium ranelate Drugs 0.000 description 3
- XXUZFRDUEGQHOV-UHFFFAOYSA-J strontium ranelate Chemical compound [Sr+2].[Sr+2].[O-]C(=O)CN(CC([O-])=O)C=1SC(C([O-])=O)=C(CC([O-])=O)C=1C#N XXUZFRDUEGQHOV-UHFFFAOYSA-J 0.000 description 3
- 229940122156 Cathepsin K inhibitor Drugs 0.000 description 2
- 101001135738 Homo sapiens Parathyroid hormone-related protein Proteins 0.000 description 2
- 239000002176 L01XE26 - Cabozantinib Substances 0.000 description 2
- 102000008108 Osteoprotegerin Human genes 0.000 description 2
- 108010035042 Osteoprotegerin Proteins 0.000 description 2
- 102100036899 Parathyroid hormone-related protein Human genes 0.000 description 2
- 108010003723 Single-Domain Antibodies Proteins 0.000 description 2
- 229960001292 cabozantinib Drugs 0.000 description 2
- ONIQOQHATWINJY-UHFFFAOYSA-N cabozantinib Chemical group C=12C=C(OC)C(OC)=CC2=NC=CC=1OC(C=C1)=CC=C1NC(=O)C1(C(=O)NC=2C=CC(F)=CC=2)CC1 ONIQOQHATWINJY-UHFFFAOYSA-N 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 239000003067 chemokine receptor CCR5 antagonist Substances 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 229960001251 denosumab Drugs 0.000 description 2
- 229940121647 egfr inhibitor Drugs 0.000 description 2
- 239000002834 estrogen receptor modulator Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- XXUPLYBCNPLTIW-UHFFFAOYSA-N octadec-7-ynoic acid Chemical compound CCCCCCCCCCC#CCCCCCC(O)=O XXUPLYBCNPLTIW-UHFFFAOYSA-N 0.000 description 2
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 description 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 description 1
- 102000004171 Cathepsin K Human genes 0.000 description 1
- 108090000625 Cathepsin K Proteins 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 102000015694 estrogen receptors Human genes 0.000 description 1
- 108010038795 estrogen receptors Proteins 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022026587A JP2022060489A (ja) | 2016-05-25 | 2022-02-24 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
| JP2024184425A JP2025003539A (ja) | 2016-05-25 | 2024-10-18 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662341333P | 2016-05-25 | 2016-05-25 | |
| US62/341,333 | 2016-05-25 | ||
| US201662344836P | 2016-06-02 | 2016-06-02 | |
| US62/344,836 | 2016-06-02 | ||
| PCT/IB2017/053094 WO2017203468A1 (en) | 2016-05-25 | 2017-05-25 | Therapeutic treatment of breast cancer based on c-maf status |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022026587A Division JP2022060489A (ja) | 2016-05-25 | 2022-02-24 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523641A JP2019523641A (ja) | 2019-08-29 |
| JP2019523641A5 true JP2019523641A5 (enExample) | 2020-07-09 |
| JP7032329B2 JP7032329B2 (ja) | 2022-03-08 |
Family
ID=59055237
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561228A Active JP7032329B2 (ja) | 2016-05-25 | 2017-05-25 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
| JP2022026587A Withdrawn JP2022060489A (ja) | 2016-05-25 | 2022-02-24 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
| JP2024184425A Pending JP2025003539A (ja) | 2016-05-25 | 2024-10-18 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022026587A Withdrawn JP2022060489A (ja) | 2016-05-25 | 2022-02-24 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
| JP2024184425A Pending JP2025003539A (ja) | 2016-05-25 | 2024-10-18 | ｃ－ＭＡＦの状態に基づく乳がんの治療的処置 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11596642B2 (enExample) |
| EP (2) | EP3901283B1 (enExample) |
| JP (3) | JP7032329B2 (enExample) |
| KR (2) | KR102867720B1 (enExample) |
| CN (2) | CN109790582B (enExample) |
| AU (1) | AU2017271385B2 (enExample) |
| CA (1) | CA3025264A1 (enExample) |
| DK (2) | DK3458610T3 (enExample) |
| ES (2) | ES3043607T3 (enExample) |
| HR (1) | HRP20210921T1 (enExample) |
| LT (1) | LT3458610T (enExample) |
| MX (1) | MX2018014279A (enExample) |
| PL (1) | PL3458610T3 (enExample) |
| PT (1) | PT3458610T (enExample) |
| WO (1) | WO2017203468A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102240323B1 (ko) | 2010-10-06 | 2021-04-14 | 펀다시오 인스티튜트 드 르세르카 바이오메디카(아이알비 바르셀로나) | 유방암 전이의 진단, 예후 및 치료 방법 |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| ES2705237T3 (es) | 2012-06-06 | 2019-03-22 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Método para el diagnóstico y el pronóstico de metástasis del cáncer de pulmón |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| CN104995313A (zh) | 2012-10-12 | 2015-10-21 | 生物运动有限公司 | 使用c-maf的前列腺癌转移的诊断、预后和治疗的方法 |
| EP2975138A2 (en) | 2013-03-15 | 2016-01-20 | Fundació Institut de Recerca Biomèdica (IRB Barcelona) | Method for the diagnosis, prognosis and treatment of cancer metastasis |
| US10793642B2 (en) | 2014-12-11 | 2020-10-06 | Inbiomotion S.L. | Binding members for human c-MAF |
| HRP20210921T1 (hr) | 2016-05-25 | 2021-09-03 | Inbiomotion S.L. | Terapijsko liječenje raka dojke na osnovi statusa c-maf |
| AU2018372762B2 (en) | 2017-11-22 | 2025-08-21 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-maf status |
| KR102191049B1 (ko) | 2019-02-22 | 2020-12-15 | 엘지전자 주식회사 | 워터 디스펜싱 장치 |
| BR112021021663A2 (pt) * | 2019-04-30 | 2022-05-17 | Inst De Medicina Molecular Joao Lobo Antunes | Inibidores da via rank em combinação com inibidores de cdk |
| JP7509400B2 (ja) * | 2020-02-18 | 2024-07-02 | 国立研究開発法人量子科学技術研究開発機構 | 投与施設ユニット |
| KR20250030194A (ko) | 2023-08-24 | 2025-03-05 | 코웨이 주식회사 | 출수 장치 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE4013632A1 (de) | 1990-04-27 | 1991-10-31 | Max Planck Gesellschaft | Liposomen mit positiver ueberschussladung |
| DE122010000048I1 (de) | 1996-12-23 | 2011-05-05 | Immunex Corp | Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| US6274338B1 (en) | 1998-02-24 | 2001-08-14 | President And Fellows Of Harvard College | Human c-Maf compositions and methods of use thereof |
| JP2002539191A (ja) | 1999-03-15 | 2002-11-19 | アクシス・ファーマシューティカルズ・インコーポレイテッド | プロテアーゼ阻害剤としての新規化合物及び組成物 |
| JP2003525874A (ja) | 2000-01-06 | 2003-09-02 | メルク フロスト カナダ アンド カンパニー | プロテアーゼ阻害剤としての新規化合物および組成物 |
| PT2295081T (pt) | 2001-06-26 | 2019-02-01 | Amgen Inc | Anticorpos contra opgl |
| GB0121033D0 (en) | 2001-08-30 | 2001-10-24 | Novartis Ag | Organic compounds |
| AR036375A1 (es) | 2001-08-30 | 2004-09-01 | Novartis Ag | Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos |
| KR100485271B1 (ko) | 2002-01-16 | 2005-04-27 | 메타볼랩(주) | 전사인자 ｃ－ｍａｆ의 전사 활성 억제제로서의 니발레놀및 그를 포함하는 약제학적 조성물 |
| SE0201980D0 (sv) | 2002-06-24 | 2002-06-24 | Astrazeneca Ab | Novel compounds |
| DE10235624A1 (de) | 2002-08-02 | 2004-02-19 | Aventis Pharma Deutschland Gmbh | Endiandric acid H und ihre Derivate, Verfahren zu ihrer Herstellung und Verwendung derselben |
| WO2004063355A2 (en) | 2003-01-10 | 2004-07-29 | Protein Design Labs, Inc. | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer |
| CN1898563B (zh) | 2003-09-24 | 2011-11-23 | 肿瘤疗法科学股份有限公司 | 诊断乳腺癌的方法 |
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| WO2005060722A2 (en) | 2003-12-18 | 2005-07-07 | President And Fellows Of Hardvard College | Modulation of immune system function by modulation of polypeptide arginine methyltransferases |
| TW200526224A (en) | 2003-12-22 | 2005-08-16 | Alcon Inc | Short form c-Maf transcription factor antagonists for treatment of glaucoma |
| EP1730308A4 (en) | 2004-03-05 | 2008-10-08 | Rosetta Inpharmatics Llc | CLASSIFICATION OF BREAST CANCER PATIENTS USING A COMBINATION OF CLINICAL CRITERIA AND INFORMATIVE SKILLS |
| WO2006012221A2 (en) | 2004-06-25 | 2006-02-02 | The Regents Of The University Of California | Target cell-specific short interfering rna and methods of use thereof |
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| CA2807557C (en) | 2009-08-06 | 2019-09-17 | Partha S. Ray | Diagnosis of primary and metastatic basal-like breast cancer and other cancer types |
| KR102240323B1 (ko) * | 2010-10-06 | 2021-04-14 | 펀다시오 인스티튜트 드 르세르카 바이오메디카(아이알비 바르셀로나) | 유방암 전이의 진단, 예후 및 치료 방법 |
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| AU2012229123B2 (en) | 2011-03-15 | 2017-02-02 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with anthracycline therapy |
| CA2856295A1 (en) | 2011-11-18 | 2013-05-23 | Vanderbilt University | Markers of triple-negative breast cancer and uses thereof |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| ES2705237T3 (es) | 2012-06-06 | 2019-03-22 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Método para el diagnóstico y el pronóstico de metástasis del cáncer de pulmón |
| CN104995313A (zh) | 2012-10-12 | 2015-10-21 | 生物运动有限公司 | 使用c-maf的前列腺癌转移的诊断、预后和治疗的方法 |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| WO2014184679A2 (en) * | 2013-03-15 | 2014-11-20 | Inbiomotion S.L. | Method for the prognosis and treatment of renal cell carcinoma metastasis |
| CA2906394A1 (en) | 2013-03-15 | 2014-09-18 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Method for the prognosis and treatment of cancer metastasis |
| EP2975138A2 (en) | 2013-03-15 | 2016-01-20 | Fundació Institut de Recerca Biomèdica (IRB Barcelona) | Method for the diagnosis, prognosis and treatment of cancer metastasis |
| EP3524698A1 (en) | 2013-10-09 | 2019-08-14 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Method for the prognosis and treatment of cancer metastasis |
| US10793642B2 (en) | 2014-12-11 | 2020-10-06 | Inbiomotion S.L. | Binding members for human c-MAF |
| HRP20210921T1 (hr) | 2016-05-25 | 2021-09-03 | Inbiomotion S.L. | Terapijsko liječenje raka dojke na osnovi statusa c-maf |
| EP3296431A1 (en) | 2016-09-15 | 2018-03-21 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Method of synthesis of an electrode for use as a catalyst of oxygen evolution reaction |
| AU2018372762B2 (en) | 2017-11-22 | 2025-08-21 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-maf status |
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2017
- 2017-05-25 HR HRP20210921TT patent/HRP20210921T1/hr unknown
- 2017-05-25 WO PCT/IB2017/053094 patent/WO2017203468A1/en not_active Ceased
- 2017-05-25 EP EP21172098.2A patent/EP3901283B1/en active Active
- 2017-05-25 KR KR1020237028682A patent/KR102867720B1/ko active Active
- 2017-05-25 DK DK17729924.5T patent/DK3458610T3/da active
- 2017-05-25 ES ES21172098T patent/ES3043607T3/es active Active
- 2017-05-25 KR KR1020187037303A patent/KR102571924B1/ko active Active
- 2017-05-25 CN CN201780042410.4A patent/CN109790582B/zh active Active
- 2017-05-25 MX MX2018014279A patent/MX2018014279A/es unknown
- 2017-05-25 ES ES17729924T patent/ES2877757T3/es active Active
- 2017-05-25 US US16/303,945 patent/US11596642B2/en active Active
- 2017-05-25 CA CA3025264A patent/CA3025264A1/en active Pending
- 2017-05-25 DK DK21172098.2T patent/DK3901283T3/da active
- 2017-05-25 PT PT177299245T patent/PT3458610T/pt unknown
- 2017-05-25 EP EP17729924.5A patent/EP3458610B1/en active Active
- 2017-05-25 AU AU2017271385A patent/AU2017271385B2/en active Active
- 2017-05-25 CN CN202311196940.8A patent/CN117230193A/zh active Pending
- 2017-05-25 LT LTEP17729924.5T patent/LT3458610T/lt unknown
- 2017-05-25 PL PL17729924T patent/PL3458610T3/pl unknown
- 2017-05-25 JP JP2018561228A patent/JP7032329B2/ja active Active
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2022
- 2022-02-24 JP JP2022026587A patent/JP2022060489A/ja not_active Withdrawn
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2023
- 2023-02-15 US US18/169,537 patent/US20230381209A1/en active Pending
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2024
- 2024-10-18 JP JP2024184425A patent/JP2025003539A/ja active Pending
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