JP2015520197A5 - - Google Patents
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- JP2015520197A5 JP2015520197A5 JP2015517568A JP2015517568A JP2015520197A5 JP 2015520197 A5 JP2015520197 A5 JP 2015520197A5 JP 2015517568 A JP2015517568 A JP 2015517568A JP 2015517568 A JP2015517568 A JP 2015517568A JP 2015520197 A5 JP2015520197 A5 JP 2015520197A5
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- hydrophobic
- targeting moiety
- hydrophilic
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- 239000000203 mixture Substances 0.000 claims 11
- 239000002105 nanoparticle Substances 0.000 claims 9
- HXITXNWTGFUOAU-UHFFFAOYSA-N phenylboronic acid Chemical compound OB(O)C1=CC=CC=C1 HXITXNWTGFUOAU-UHFFFAOYSA-N 0.000 claims 7
- 230000002209 hydrophobic effect Effects 0.000 claims 6
- 230000008685 targeting Effects 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 3
- 229920002521 macromolecule Polymers 0.000 claims 3
- 229920000747 poly(lactic acid) Polymers 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 229920002307 Dextran Polymers 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000001268 conjugating effect Effects 0.000 claims 2
- 229920001477 hydrophilic polymer Polymers 0.000 claims 2
- 229920001600 hydrophobic polymer Polymers 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 1
- 229920000249 biocompatible polymer Polymers 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 229920000359 diblock copolymer Polymers 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 125000003396 thiol group Chemical class [H]S* 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261690127P | 2012-06-20 | 2012-06-20 | |
| US61/690,127 | 2012-06-20 | ||
| PCT/CA2013/050475 WO2013188979A1 (en) | 2012-06-20 | 2013-06-20 | Mucoadhesive nanoparticle delivery system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520197A JP2015520197A (ja) | 2015-07-16 |
| JP2015520197A5 true JP2015520197A5 (enExample) | 2016-09-15 |
| JP6275707B2 JP6275707B2 (ja) | 2018-02-07 |
Family
ID=49767986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517568A Active JP6275707B2 (ja) | 2012-06-20 | 2013-06-20 | 粘膜付着性ナノ粒子送達系 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20140005379A1 (enExample) |
| EP (1) | EP2863892B1 (enExample) |
| JP (1) | JP6275707B2 (enExample) |
| KR (1) | KR102177557B1 (enExample) |
| CN (1) | CN104507458B (enExample) |
| CA (1) | CA2877051C (enExample) |
| ES (1) | ES2658972T3 (enExample) |
| WO (1) | WO2013188979A1 (enExample) |
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| WO2009049089A1 (en) * | 2007-10-09 | 2009-04-16 | Washington University In St. Louis | Ligand directed toroidal nanoparticles for therapy and diagnostic imaging |
| US8603532B2 (en) | 2008-10-20 | 2013-12-10 | Massachusetts Institute Of Technology | Nanostructures for drug delivery |
| BRPI1008602A8 (pt) | 2009-02-18 | 2018-01-02 | Eyeon Particle Sciences Llc | uso de co-polímero bi-funcional para as aplicações oftálmicas e outras aplicações tópicas e locais |
| EP2493458A2 (en) | 2009-10-30 | 2012-09-05 | The Ohio State University | Multi-functional biodegradable particles for selectable targeting, imaging, and therapeutic delivery and use thereof for treating ocular disorders |
| JP5560719B2 (ja) * | 2010-01-08 | 2014-07-30 | 東レ株式会社 | 親水性生理活性物質含有微粒子の製造方法 |
| WO2012097049A2 (en) * | 2011-01-11 | 2012-07-19 | The University Of North Carolina At Chapel Hill | Dna repair enzyme inhibitor nanoparticles and uses thereof |
| EP2510930A1 (en) | 2011-04-15 | 2012-10-17 | Bionanoplus, S.L. | Nanoparticles comprising half esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof |
| US9101547B2 (en) | 2011-08-04 | 2015-08-11 | Nano And Advanced Materials Institute Limited | Enteric-coated capsule containing cationic nanoparticles for oral insulin delivery |
| EP2863892B1 (en) | 2012-06-20 | 2017-11-08 | University Of Waterloo | Mucoadhesive nanoparticle delivery system |
| US9878000B2 (en) | 2012-06-20 | 2018-01-30 | University Of Waterloo | Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof |
-
2013
- 2013-06-20 EP EP13806729.3A patent/EP2863892B1/en active Active
- 2013-06-20 ES ES13806729.3T patent/ES2658972T3/es active Active
- 2013-06-20 KR KR1020157001443A patent/KR102177557B1/ko not_active Expired - Fee Related
- 2013-06-20 JP JP2015517568A patent/JP6275707B2/ja active Active
- 2013-06-20 CA CA2877051A patent/CA2877051C/en active Active
- 2013-06-20 US US13/923,274 patent/US20140005379A1/en not_active Abandoned
- 2013-06-20 WO PCT/CA2013/050475 patent/WO2013188979A1/en not_active Ceased
- 2013-06-20 US US14/410,521 patent/US9993439B2/en active Active
- 2013-06-20 CN CN201380040130.1A patent/CN104507458B/zh active Active
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