JP2015518569A5 - - Google Patents
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- Publication number
- JP2015518569A5 JP2015518569A5 JP2015510354A JP2015510354A JP2015518569A5 JP 2015518569 A5 JP2015518569 A5 JP 2015518569A5 JP 2015510354 A JP2015510354 A JP 2015510354A JP 2015510354 A JP2015510354 A JP 2015510354A JP 2015518569 A5 JP2015518569 A5 JP 2015518569A5
- Authority
- JP
- Japan
- Prior art keywords
- solid matrix
- nucleic acid
- matrix
- sample
- beauty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011159 matrix material Substances 0.000 claims 28
- 239000007787 solid Substances 0.000 claims 25
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 230000003796 beauty Effects 0.000 claims 5
- 239000002516 radical scavenger Substances 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 4
- 239000001913 cellulose Substances 0.000 claims 4
- 239000003638 chemical reducing agent Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims 4
- PZBFGYYEXUXCOF-UHFFFAOYSA-N TCEP Chemical compound OC(=O)CCP(CCC(O)=O)CCC(O)=O PZBFGYYEXUXCOF-UHFFFAOYSA-N 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims 3
- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 claims 3
- NWVVVBRKAWDGAB-UHFFFAOYSA-N p-methoxyphenol Chemical compound COC1=CC=C(O)C=C1 NWVVVBRKAWDGAB-UHFFFAOYSA-N 0.000 claims 3
- 239000003161 ribonuclease inhibitor Substances 0.000 claims 3
- CNHDIAIOKMXOLK-UHFFFAOYSA-N toluquinol Chemical compound CC1=CC(O)=CC=C1O CNHDIAIOKMXOLK-UHFFFAOYSA-N 0.000 claims 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 2
- 229960005070 ascorbic acid Drugs 0.000 claims 2
- 235000010323 ascorbic acid Nutrition 0.000 claims 2
- 239000011668 ascorbic acid Substances 0.000 claims 2
- 239000006172 buffering agent Substances 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 2
- 239000003365 glass fiber Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- 239000007993 MOPS buffer Substances 0.000 claims 1
- 239000007983 Tris buffer Substances 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000003398 denaturant Substances 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical group [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000002342 ribonucleoside Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical group OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
- -1 vanadyl ribonucleoside Chemical compound 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/460,076 | 2012-04-30 | ||
| US13/460,076 US9044738B2 (en) | 2012-04-30 | 2012-04-30 | Methods and compositions for extraction and storage of nucleic acids |
| PCT/US2013/038576 WO2013165870A1 (en) | 2012-04-30 | 2013-04-29 | Methods and compositions for extraction and storage of nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017225326A Division JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518569A JP2015518569A (ja) | 2015-07-02 |
| JP2015518569A5 true JP2015518569A5 (enExample) | 2016-06-09 |
| JP6248095B2 JP6248095B2 (ja) | 2017-12-13 |
Family
ID=49477845
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015510354A Active JP6248095B2 (ja) | 2012-04-30 | 2013-04-29 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2017225326A Active JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2020036905A Pending JP2020092709A (ja) | 2012-04-30 | 2020-03-04 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017225326A Active JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2020036905A Pending JP2020092709A (ja) | 2012-04-30 | 2020-03-04 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9044738B2 (enExample) |
| EP (1) | EP2844755B1 (enExample) |
| JP (3) | JP6248095B2 (enExample) |
| CN (1) | CN104254776B (enExample) |
| CA (1) | CA2870038C (enExample) |
| ES (1) | ES2609763T3 (enExample) |
| IN (1) | IN2014DN08223A (enExample) |
| WO (1) | WO2013165870A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9480966B2 (en) | 2012-04-30 | 2016-11-01 | General Electric Company | Substrates and methods for collection, stabilization and elution of biomolecules |
| US10829291B2 (en) * | 2012-06-20 | 2020-11-10 | Thermo Fischer Scientific Baltics UAB | Method to prevent silica-based column aging |
| SG11201601114PA (en) * | 2013-08-16 | 2016-03-30 | Gen Electric | Methods and compositions for extraction and storage of nucleic acids |
| WO2015191632A1 (en) | 2014-06-10 | 2015-12-17 | Biomatrica, Inc. | Stabilization of thrombocytes at ambient temperatures |
| CN107076764A (zh) * | 2014-11-20 | 2017-08-18 | 通用电气医疗集团英国有限公司 | 检测稳定在固体载体材料上的痴呆和阿尔茨海默病相关生物标记 |
| GB201505516D0 (en) * | 2015-03-31 | 2015-05-13 | Ge Healthcare Uk Ltd | Improvements in and relating to biological sample collectors and handling thereof |
| HK1258397A1 (zh) | 2015-09-09 | 2019-11-08 | Drawbridge Health, Inc. | 用於样品收集、稳定化和保存的系统、方法和装置 |
| US10000742B2 (en) * | 2015-11-19 | 2018-06-19 | General Electric Company | Device and method of collection for RNA viruses |
| ES2946184T3 (es) | 2015-12-08 | 2023-07-13 | Biomatrica Inc | Reducción de la velocidad de eritrosedimentación |
| US11566290B2 (en) | 2016-03-18 | 2023-01-31 | Hummingbird Diagnostics Gmbh | Purification of RNA fractions using a hydrophilic polymeric material |
| CN105961375A (zh) * | 2016-07-13 | 2016-09-28 | 北京中科唯新生物医学研究所有限公司 | 一种唾液保存液及其制备方法和用途 |
| US11166658B2 (en) * | 2016-07-28 | 2021-11-09 | Invitae Corporation | Blood sampling system and method |
| CN110072989A (zh) * | 2016-10-24 | 2019-07-30 | 生物马特里卡公司 | 核酸在纸上的稳定化 |
| SG10201911879UA (en) | 2017-01-10 | 2020-01-30 | Drawbridge Health Inc | Devices, systems, and methods for sample collection |
| CN109182332A (zh) * | 2018-09-30 | 2019-01-11 | 浙江天杭生物科技股份有限公司 | 一种从临床样品中快速简便提取核酸的方法 |
| WO2020153248A1 (ja) * | 2019-01-25 | 2020-07-30 | 積水化学工業株式会社 | 核酸の単離方法、核酸の単離キット、及び検査チップ |
| JP2023526038A (ja) * | 2020-05-14 | 2023-06-20 | バイオエコー ライフ サイエンシズ ゲーエムベーハー | 上昇させた温度での核酸の単離 |
| CN116057177A (zh) | 2020-08-28 | 2023-05-02 | 花王株式会社 | Rna的保存方法 |
| EP4308724A4 (en) * | 2021-03-19 | 2025-05-14 | Becton, Dickinson and Company | ISOTHERMAL AMPLIFICATION OF PATHOGENS |
| GB202211645D0 (en) | 2022-08-09 | 2022-09-21 | Hemodx As | Kit |
| SE548123C2 (en) * | 2023-11-08 | 2026-03-31 | Sequrna Ab | Device for dry storage of biological samples, conserving RNA from degradation and use of such devices |
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| US4540506A (en) | 1983-04-15 | 1985-09-10 | Genex Corporation | Composition for cleaning drains clogged with deposits containing hair |
| CA1255197A (en) * | 1984-09-24 | 1989-06-06 | Joseph L. Orlik | Leukocyte differentiation composition and method |
| US5173422A (en) | 1986-08-22 | 1992-12-22 | Miles Inc. | Monoclonal antibodies specific for human glycoalbumin |
| US5756126A (en) | 1991-05-29 | 1998-05-26 | Flinders Technologies Pty. Ltd. | Dry solid medium for storage and analysis of genetic material |
| US6627226B2 (en) | 1988-10-05 | 2003-09-30 | Whatman, Inc. | Dry solid medium for storage and analysis of genetic material |
| US5807527A (en) | 1991-05-29 | 1998-09-15 | Flinders Technologies Pty. Ltd. | Solid medium and method for DNA storage |
| EP1484111B1 (en) | 1995-06-07 | 2010-10-20 | WHATMAN plc | Dry solid medium for storage and analysis of genetic material |
| US5981218A (en) | 1995-08-09 | 1999-11-09 | Bristol-Myers Squibb Company | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
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| US6602718B1 (en) | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
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| AU2010229490B2 (en) * | 2009-03-24 | 2015-02-12 | University Of Chicago | Slip chip device and methods |
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| CA2796729C (en) | 2010-04-20 | 2020-06-23 | Octapharma Ag | Melezitose for stabilizing human blood plasma proteins |
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| WO2012075471A1 (en) | 2010-12-04 | 2012-06-07 | Hui-Yu Liu | Rna stability enhancer |
| US20120152743A1 (en) | 2010-12-17 | 2012-06-21 | General Electric Company | Method for electroeluting genetic material from dried samples |
| GB201103257D0 (en) | 2011-02-25 | 2011-04-13 | Ge Healthcare Uk Ltd | Paper support and method of recovering biological material therefrom |
| GB2496122A (en) | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
| CN103173432B (zh) * | 2011-12-22 | 2020-08-04 | 通用电气公司 | 分离核酸的方法及装置 |
| US9040675B2 (en) | 2012-04-30 | 2015-05-26 | General Electric Company | Formulations for nucleic acid stabilization on solid substrates |
-
2012
- 2012-04-30 US US13/460,076 patent/US9044738B2/en active Active
-
2013
- 2013-04-29 ES ES13784927.9T patent/ES2609763T3/es active Active
- 2013-04-29 WO PCT/US2013/038576 patent/WO2013165870A1/en not_active Ceased
- 2013-04-29 EP EP13784927.9A patent/EP2844755B1/en active Active
- 2013-04-29 CA CA2870038A patent/CA2870038C/en active Active
- 2013-04-29 JP JP2015510354A patent/JP6248095B2/ja active Active
- 2013-04-29 IN IN8223DEN2014 patent/IN2014DN08223A/en unknown
- 2013-04-29 CN CN201380022584.6A patent/CN104254776B/zh active Active
-
2017
- 2017-11-24 JP JP2017225326A patent/JP6847365B2/ja active Active
-
2020
- 2020-03-04 JP JP2020036905A patent/JP2020092709A/ja active Pending
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