JP2015518569A5 - - Google Patents
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- Publication number
- JP2015518569A5 JP2015518569A5 JP2015510354A JP2015510354A JP2015518569A5 JP 2015518569 A5 JP2015518569 A5 JP 2015518569A5 JP 2015510354 A JP2015510354 A JP 2015510354A JP 2015510354 A JP2015510354 A JP 2015510354A JP 2015518569 A5 JP2015518569 A5 JP 2015518569A5
- Authority
- JP
- Japan
- Prior art keywords
- solid matrix
- nucleic acid
- matrix
- sample
- beauty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011159 matrix material Substances 0.000 claims 28
- 239000007787 solid Substances 0.000 claims 25
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 230000003796 beauty Effects 0.000 claims 5
- 239000002516 radical scavenger Substances 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 4
- 239000001913 cellulose Substances 0.000 claims 4
- 239000003638 chemical reducing agent Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims 4
- PZBFGYYEXUXCOF-UHFFFAOYSA-N TCEP Chemical compound OC(=O)CCP(CCC(O)=O)CCC(O)=O PZBFGYYEXUXCOF-UHFFFAOYSA-N 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims 3
- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 claims 3
- NWVVVBRKAWDGAB-UHFFFAOYSA-N p-methoxyphenol Chemical compound COC1=CC=C(O)C=C1 NWVVVBRKAWDGAB-UHFFFAOYSA-N 0.000 claims 3
- 239000003161 ribonuclease inhibitor Substances 0.000 claims 3
- CNHDIAIOKMXOLK-UHFFFAOYSA-N toluquinol Chemical compound CC1=CC(O)=CC=C1O CNHDIAIOKMXOLK-UHFFFAOYSA-N 0.000 claims 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 2
- 229960005070 ascorbic acid Drugs 0.000 claims 2
- 235000010323 ascorbic acid Nutrition 0.000 claims 2
- 239000011668 ascorbic acid Substances 0.000 claims 2
- 239000006172 buffering agent Substances 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 2
- 239000003365 glass fiber Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- 239000007993 MOPS buffer Substances 0.000 claims 1
- 239000007983 Tris buffer Substances 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000003398 denaturant Substances 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical group [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000002342 ribonucleoside Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical group OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
- -1 vanadyl ribonucleoside Chemical compound 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/460,076 | 2012-04-30 | ||
| US13/460,076 US9044738B2 (en) | 2012-04-30 | 2012-04-30 | Methods and compositions for extraction and storage of nucleic acids |
| PCT/US2013/038576 WO2013165870A1 (en) | 2012-04-30 | 2013-04-29 | Methods and compositions for extraction and storage of nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017225326A Division JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518569A JP2015518569A (ja) | 2015-07-02 |
| JP2015518569A5 true JP2015518569A5 (enExample) | 2016-06-09 |
| JP6248095B2 JP6248095B2 (ja) | 2017-12-13 |
Family
ID=49477845
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015510354A Active JP6248095B2 (ja) | 2012-04-30 | 2013-04-29 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2017225326A Active JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2020036905A Pending JP2020092709A (ja) | 2012-04-30 | 2020-03-04 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017225326A Active JP6847365B2 (ja) | 2012-04-30 | 2017-11-24 | 核酸の抽出及び貯蔵のための方法及び組成物 |
| JP2020036905A Pending JP2020092709A (ja) | 2012-04-30 | 2020-03-04 | 核酸の抽出及び貯蔵のための方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9044738B2 (enExample) |
| EP (1) | EP2844755B1 (enExample) |
| JP (3) | JP6248095B2 (enExample) |
| CN (1) | CN104254776B (enExample) |
| CA (1) | CA2870038C (enExample) |
| ES (1) | ES2609763T3 (enExample) |
| IN (1) | IN2014DN08223A (enExample) |
| WO (1) | WO2013165870A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9480966B2 (en) | 2012-04-30 | 2016-11-01 | General Electric Company | Substrates and methods for collection, stabilization and elution of biomolecules |
| US10829291B2 (en) * | 2012-06-20 | 2020-11-10 | Thermo Fischer Scientific Baltics UAB | Method to prevent silica-based column aging |
| MX371517B (es) * | 2013-08-16 | 2020-01-31 | Gen Electric | Metodos y composiciones para la extraccion y el almacenamiento de acidos nucleicos. |
| CN113826612B (zh) | 2014-06-10 | 2022-11-22 | 生物马特里卡公司 | 在环境温度下稳定凝血细胞 |
| JP2018502281A (ja) * | 2014-11-20 | 2018-01-25 | ジーイー・ヘルスケア・ユーケイ・リミテッド | 固体支持体材料に固定された認知症及びアルツハイマー病関連バイオマーカーの検出 |
| GB201505516D0 (en) * | 2015-03-31 | 2015-05-13 | Ge Healthcare Uk Ltd | Improvements in and relating to biological sample collectors and handling thereof |
| US11266337B2 (en) | 2015-09-09 | 2022-03-08 | Drawbridge Health, Inc. | Systems, methods, and devices for sample collection, stabilization and preservation |
| US10000742B2 (en) * | 2015-11-19 | 2018-06-19 | General Electric Company | Device and method of collection for RNA viruses |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| SG10202010005TA (en) | 2016-03-18 | 2020-11-27 | Hummingbird Diagnostics Gmbh | Purification of rna fractions using a hydrophilic polymeric material |
| CN105961375A (zh) * | 2016-07-13 | 2016-09-28 | 北京中科唯新生物医学研究所有限公司 | 一种唾液保存液及其制备方法和用途 |
| US11166658B2 (en) * | 2016-07-28 | 2021-11-09 | Invitae Corporation | Blood sampling system and method |
| WO2018081161A1 (en) * | 2016-10-24 | 2018-05-03 | Biomatrica, Inc. | Stabilization of nucleic acids on paper |
| BR112019014231A2 (pt) | 2017-01-10 | 2020-03-17 | Drawbridge Health, Inc. | Dispositivos, sistemas e métodos para coleta de amostra |
| CN109182332A (zh) * | 2018-09-30 | 2019-01-11 | 浙江天杭生物科技股份有限公司 | 一种从临床样品中快速简便提取核酸的方法 |
| WO2020153248A1 (ja) * | 2019-01-25 | 2020-07-30 | 積水化学工業株式会社 | 核酸の単離方法、核酸の単離キット、及び検査チップ |
| JP2023526038A (ja) * | 2020-05-14 | 2023-06-20 | バイオエコー ライフ サイエンシズ ゲーエムベーハー | 上昇させた温度での核酸の単離 |
| WO2022045303A1 (ja) | 2020-08-28 | 2022-03-03 | 花王株式会社 | Ｒｎａの保存方法 |
| GB202211645D0 (en) | 2022-08-09 | 2022-09-21 | Hemodx As | Kit |
| SE2351278A1 (en) * | 2023-11-08 | 2025-05-09 | Sequrna Ab | Dry storage |
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| US4540506A (en) | 1983-04-15 | 1985-09-10 | Genex Corporation | Composition for cleaning drains clogged with deposits containing hair |
| CA1255197A (en) * | 1984-09-24 | 1989-06-06 | Joseph L. Orlik | Leukocyte differentiation composition and method |
| US5173422A (en) | 1986-08-22 | 1992-12-22 | Miles Inc. | Monoclonal antibodies specific for human glycoalbumin |
| US6627226B2 (en) | 1988-10-05 | 2003-09-30 | Whatman, Inc. | Dry solid medium for storage and analysis of genetic material |
| US5756126A (en) | 1991-05-29 | 1998-05-26 | Flinders Technologies Pty. Ltd. | Dry solid medium for storage and analysis of genetic material |
| US5807527A (en) | 1991-05-29 | 1998-09-15 | Flinders Technologies Pty. Ltd. | Solid medium and method for DNA storage |
| DE69633239T2 (de) | 1995-06-07 | 2005-09-08 | Whatman Plc, Maidstone | Trockenes festes medium zur lagerung und analyse von genetischem material |
| WO1997006256A2 (en) | 1995-08-09 | 1997-02-20 | Institut National De La Sante Et De La Recherche Medicale | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis |
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| EP1175431A4 (en) | 1999-04-30 | 2002-09-11 | Whatman Inc | SUBSTRATE CONTAINING ANIONIC NUCLEIC ACID PURIFICATION DETERGENT |
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| CN101878304B (zh) * | 2007-11-30 | 2015-01-07 | 通用电气医疗集团生物科学公司 | 用于从单个样品中分离基因组dna、rna和蛋白质的方法 |
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| CN102177237B (zh) | 2008-09-12 | 2013-10-30 | 金沃特公司 | 用于贮存和稳定生物分子的基质和介质 |
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| JP5933544B2 (ja) | 2010-07-26 | 2016-06-08 | バイオマトリカ， インコーポレーテッド | 外界温度で出荷および貯蔵中の血中ｄｎａ、ｒｎａおよびタンパク質ならびに他の生体試料を安定化させるための組成物 |
| CN103370412B (zh) | 2010-12-04 | 2015-07-22 | 万芬 | 核糖核酸稳定性增强剂 |
| US20120152743A1 (en) | 2010-12-17 | 2012-06-21 | General Electric Company | Method for electroeluting genetic material from dried samples |
| GB201103257D0 (en) | 2011-02-25 | 2011-04-13 | Ge Healthcare Uk Ltd | Paper support and method of recovering biological material therefrom |
| GB2496122A (en) | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
| CN103173432B (zh) * | 2011-12-22 | 2020-08-04 | 通用电气公司 | 分离核酸的方法及装置 |
| US9040675B2 (en) | 2012-04-30 | 2015-05-26 | General Electric Company | Formulations for nucleic acid stabilization on solid substrates |
-
2012
- 2012-04-30 US US13/460,076 patent/US9044738B2/en active Active
-
2013
- 2013-04-29 CN CN201380022584.6A patent/CN104254776B/zh active Active
- 2013-04-29 EP EP13784927.9A patent/EP2844755B1/en active Active
- 2013-04-29 IN IN8223DEN2014 patent/IN2014DN08223A/en unknown
- 2013-04-29 JP JP2015510354A patent/JP6248095B2/ja active Active
- 2013-04-29 WO PCT/US2013/038576 patent/WO2013165870A1/en not_active Ceased
- 2013-04-29 CA CA2870038A patent/CA2870038C/en active Active
- 2013-04-29 ES ES13784927.9T patent/ES2609763T3/es active Active
-
2017
- 2017-11-24 JP JP2017225326A patent/JP6847365B2/ja active Active
-
2020
- 2020-03-04 JP JP2020036905A patent/JP2020092709A/ja active Pending
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