SG11201806794RA - Purification of rna fractions using a hydrophilic polymeric material - Google Patents
Purification of rna fractions using a hydrophilic polymeric materialInfo
- Publication number
- SG11201806794RA SG11201806794RA SG11201806794RA SG11201806794RA SG11201806794RA SG 11201806794R A SG11201806794R A SG 11201806794RA SG 11201806794R A SG11201806794R A SG 11201806794RA SG 11201806794R A SG11201806794R A SG 11201806794RA SG 11201806794R A SG11201806794R A SG 11201806794RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- present
- relates
- nucleotides
- pct
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4055—Concentrating samples by solubility techniques
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 21 September 2017 (21.09.2017) WIPO I PCT (10) International Publication Number WO 2017/157650 Al 111111111111110111011111111111010111110 0111111111111111111111111111111111111110111111 (51) International Patent Classification: G01N 1/34 (2006.01) GO1N 1/40 (2006.01) (21) International Application Number: PCT/EP2017/054582 (22) International Filing Date: 28 February 2017 (28.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16161077.9 18 March 2016 (18.03.2016) EP (71) Applicant: HUMMINGBIRD DIAGNOSTICS GMBH [DE/DE]; Im Neuenheimer Feld 583, 69120 Heidelberg (DE). (72) Inventors: LAUFER, Thomas; Lessingstr. 17, 68535 Edingen-Neckarhausen (DE). BEIER, Markus; Marc- Aurel-Weg 20, 69469 Weinheim (DE). KAHRAMAN, Mustafa; Waldhausweg 7, 66123 Saarbriicken (DE). KELLER, Andreas; Albert-Schweitzer-Str. 6, 66346 Piit- tlingen (DE). (74) Agent: GEEING, Andrea; ZSP Patentanwalte PartG mbB, Hansastrasse 32, 80686 Miinchen (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) W O 20 17157 / 65 0 Al (54) Title: PURIFICATION OF RNA FRACTIONS USING A HYDROPHILIC POLYMERIC MATERIAL (57) : The present invention relates to a method of removing an RNA fraction with > 200 nucleotides in length from a whole blood sample. The present invention also relates to a method of purifying an RNA fraction with < 200 nucleotides in length from a whole blood sample. The present invention further relates to a method of determining the level of RNA molecules with < 200 nucleotides in length. In addition, the present invention relates to a method for diagnosing a disease in an individual. Moreover, the present invention relates to a kit which is useful for carrying out the methods of the present invention.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16161077 | 2016-03-18 | ||
PCT/EP2017/054582 WO2017157650A1 (en) | 2016-03-18 | 2017-02-28 | Purification of rna fractions using a hydrophilic polymeric material |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201806794RA true SG11201806794RA (en) | 2018-09-27 |
Family
ID=55587144
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201806794RA SG11201806794RA (en) | 2016-03-18 | 2017-02-28 | Purification of rna fractions using a hydrophilic polymeric material |
SG10202010005TA SG10202010005TA (en) | 2016-03-18 | 2017-02-28 | Purification of rna fractions using a hydrophilic polymeric material |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010005TA SG10202010005TA (en) | 2016-03-18 | 2017-02-28 | Purification of rna fractions using a hydrophilic polymeric material |
Country Status (11)
Country | Link |
---|---|
US (1) | US11566290B2 (en) |
EP (1) | EP3430373B1 (en) |
JP (1) | JP7093305B2 (en) |
CN (1) | CN109154544B (en) |
AU (1) | AU2017233436B2 (en) |
DK (1) | DK3430373T3 (en) |
ES (1) | ES2952950T3 (en) |
FI (1) | FI3430373T3 (en) |
PL (1) | PL3430373T3 (en) |
SG (2) | SG11201806794RA (en) |
WO (1) | WO2017157650A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10656059B2 (en) | 2018-03-07 | 2020-05-19 | Alcala Pharmaceutical, Inc. | Method for qualitative and quantitative multiplexing of drug analytes from biological samples |
US11162921B2 (en) | 2019-04-01 | 2021-11-02 | Alcala Pharmaceutical, Inc. | Method for extracting pharmacogenetic DNA from biological fluid retained in a solid resin collection device |
GB2623570A (en) * | 2022-10-21 | 2024-04-24 | Wobble Genomics Ltd | Method and products for biomarker identification |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6627226B2 (en) | 1988-10-05 | 2003-09-30 | Whatman, Inc. | Dry solid medium for storage and analysis of genetic material |
DE102005059315A1 (en) | 2005-12-09 | 2007-06-14 | Qiagen Gmbh | Process for the enrichment of short-chain nucleic acids |
EP2407540A1 (en) | 2010-07-15 | 2012-01-18 | Qiagen GmbH | Method for purifying a target nucleic acid |
WO2013022342A1 (en) | 2011-08-09 | 2013-02-14 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | A method of analysing a blood sample of a subject for the presence of a foetal disease or condition marker |
WO2013043562A1 (en) | 2011-09-23 | 2013-03-28 | Waters Technologies Corporation | Solid phase extraction device for dried sample cards |
US20130116597A1 (en) | 2011-11-04 | 2013-05-09 | Phenomenex, Inc. | Method and apparatus for acquiring blood for testing |
US9044738B2 (en) | 2012-04-30 | 2015-06-02 | General Electric Company | Methods and compositions for extraction and storage of nucleic acids |
WO2014143714A2 (en) * | 2013-03-15 | 2014-09-18 | Ge Healthcare Uk Limited | Methods for one step nucleic acid amplification of non-eluted samples |
ES2705574T3 (en) | 2013-10-22 | 2019-03-26 | Hoffmann La Roche | Procedures for measuring cell-free virus particles from drops of dried blood |
-
2017
- 2017-02-28 US US16/079,035 patent/US11566290B2/en active Active
- 2017-02-28 AU AU2017233436A patent/AU2017233436B2/en active Active
- 2017-02-28 DK DK17707850.8T patent/DK3430373T3/en active
- 2017-02-28 WO PCT/EP2017/054582 patent/WO2017157650A1/en active Application Filing
- 2017-02-28 EP EP17707850.8A patent/EP3430373B1/en active Active
- 2017-02-28 ES ES17707850T patent/ES2952950T3/en active Active
- 2017-02-28 SG SG11201806794RA patent/SG11201806794RA/en unknown
- 2017-02-28 PL PL17707850.8T patent/PL3430373T3/en unknown
- 2017-02-28 CN CN201780018265.6A patent/CN109154544B/en active Active
- 2017-02-28 SG SG10202010005TA patent/SG10202010005TA/en unknown
- 2017-02-28 FI FIEP17707850.8T patent/FI3430373T3/en active
- 2017-02-28 JP JP2018549217A patent/JP7093305B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2017233436A1 (en) | 2018-10-11 |
EP3430373A1 (en) | 2019-01-23 |
WO2017157650A1 (en) | 2017-09-21 |
JP7093305B2 (en) | 2022-06-29 |
JP2019513352A (en) | 2019-05-30 |
US20200199672A1 (en) | 2020-06-25 |
AU2017233436B2 (en) | 2022-11-24 |
EP3430373B1 (en) | 2023-07-05 |
US11566290B2 (en) | 2023-01-31 |
DK3430373T3 (en) | 2023-10-02 |
CN109154544A (en) | 2019-01-04 |
PL3430373T3 (en) | 2023-10-30 |
CN109154544B (en) | 2024-05-14 |
FI3430373T3 (en) | 2023-08-18 |
ES2952950T3 (en) | 2023-11-07 |
SG10202010005TA (en) | 2020-11-27 |
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