JP2015512386A5 - - Google Patents
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- Publication number
- JP2015512386A5 JP2015512386A5 JP2015501713A JP2015501713A JP2015512386A5 JP 2015512386 A5 JP2015512386 A5 JP 2015512386A5 JP 2015501713 A JP2015501713 A JP 2015501713A JP 2015501713 A JP2015501713 A JP 2015501713A JP 2015512386 A5 JP2015512386 A5 JP 2015512386A5
- Authority
- JP
- Japan
- Prior art keywords
- lysine
- formulation
- proline
- palmitoyl
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 238000009472 formulation Methods 0.000 claims 11
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 5
- 239000004472 Lysine Substances 0.000 claims 5
- 150000002632 lipids Chemical class 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 208000015181 infectious disease Diseases 0.000 claims 4
- 230000000813 microbial effect Effects 0.000 claims 4
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 3
- 208000002874 Acne Vulgaris Diseases 0.000 claims 2
- 241001303601 Rosacea Species 0.000 claims 2
- 206010000496 acne Diseases 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 206010020718 hyperplasia Diseases 0.000 claims 2
- 230000002390 hyperplastic effect Effects 0.000 claims 2
- 201000004700 rosacea Diseases 0.000 claims 2
- 231100000241 scar Toxicity 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- 208000035985 Body Odor Diseases 0.000 claims 1
- 206010006326 Breath odour Diseases 0.000 claims 1
- 241000222122 Candida albicans Species 0.000 claims 1
- 241000186427 Cutibacterium acnes Species 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 206010016936 Folliculitis Diseases 0.000 claims 1
- 206010040904 Skin odour abnormal Diseases 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 229940095731 candida albicans Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000024693 gingival disease Diseases 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 229940055019 propionibacterium acne Drugs 0.000 claims 1
- 210000004761 scalp Anatomy 0.000 claims 1
- 206010040872 skin infection Diseases 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 claims 1
- 201000004647 tinea pedis Diseases 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000008736 traumatic injury Effects 0.000 claims 1
- 208000013464 vaginal disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261613212P | 2012-03-20 | 2012-03-20 | |
| US61/613,212 | 2012-03-20 | ||
| PCT/US2013/029696 WO2013142088A1 (en) | 2012-03-20 | 2013-03-07 | Short antimicrobial lipopeptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512386A JP2015512386A (ja) | 2015-04-27 |
| JP2015512386A5 true JP2015512386A5 (https=) | 2016-04-07 |
| JP6261560B2 JP6261560B2 (ja) | 2018-01-17 |
Family
ID=47901428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015501713A Expired - Fee Related JP6261560B2 (ja) | 2012-03-20 | 2013-03-07 | 抗微生物性の短リポペプチド |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9278994B2 (https=) |
| EP (1) | EP2827907B1 (https=) |
| JP (1) | JP6261560B2 (https=) |
| KR (1) | KR20140136494A (https=) |
| CN (2) | CN107080831A (https=) |
| AR (1) | AR090439A1 (https=) |
| AU (1) | AU2013235692B2 (https=) |
| CA (1) | CA2864179A1 (https=) |
| DK (1) | DK2827907T3 (https=) |
| ES (1) | ES2729237T3 (https=) |
| MX (1) | MX2014011290A (https=) |
| MY (1) | MY163100A (https=) |
| PL (1) | PL2827907T3 (https=) |
| RU (2) | RU2627648C2 (https=) |
| SG (2) | SG11201405244RA (https=) |
| TW (1) | TWI541254B (https=) |
| WO (1) | WO2013142088A1 (https=) |
| ZA (1) | ZA201405950B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016002767A1 (ja) * | 2014-06-30 | 2016-01-07 | ロート製薬株式会社 | 外用組成物 |
| JP6906274B2 (ja) * | 2014-06-30 | 2021-07-21 | ロート製薬株式会社 | 外用組成物、眼科用組成物、抗菌剤、及び抗菌方法 |
| WO2017035345A1 (en) * | 2015-08-26 | 2017-03-02 | The General Hospital Corporation | System and method for electrical control of bacteria |
| KR101855170B1 (ko) * | 2015-11-18 | 2018-05-08 | (주)노바셀테크놀로지 | 신규 항균 펩타이드 및 그의 용도 |
| CN109320585B (zh) * | 2018-09-06 | 2021-10-26 | 南方医科大学 | 一种具有专一性抗痤疮丙酸杆菌作用及抗炎作用的短脂肽 |
| WO2020051707A1 (en) * | 2018-09-12 | 2020-03-19 | The Governing Council Of The University Of Toronto | Indole-oxadiazole compounds and their therapeutic use |
| CN111035764B (zh) * | 2018-10-14 | 2021-09-07 | 深圳市健元医药科技有限公司 | 一种治疗类风湿性关节炎的组合物及其制备方法 |
| CN110279844A (zh) * | 2019-01-31 | 2019-09-27 | 浙江星杭泰乐生物医药有限公司 | 人工合成抗菌肽在制备抑菌消炎祛痘化妆品或外用药物制剂中的应用及抑菌消炎祛痘组合物 |
| CN111303242B (zh) * | 2020-02-27 | 2022-04-26 | 广州领晟医疗科技有限公司 | 一种KdPT的修饰肽 |
| KR102163568B1 (ko) * | 2020-08-21 | 2020-10-07 | 주식회사 비드테크 | 지방산 항균펩타이드 및 이를 함유하는 항균 조성물 |
| CA3193765A1 (en) * | 2020-09-29 | 2022-04-07 | Anindya Dasgupta | A personal care composition comprising amino acids |
| US11793746B2 (en) * | 2020-10-01 | 2023-10-24 | Chanda Zaveri | Intense skin hydration systems and methods |
| CN112679576B (zh) * | 2020-11-06 | 2022-09-20 | 黄石瀚海新材料科技有限公司 | 抗菌脂肽、抗菌脂肽水凝胶制备方法及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993008815A1 (en) * | 1991-10-28 | 1993-05-13 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
| JP3273314B2 (ja) * | 1998-08-12 | 2002-04-08 | 独立行政法人農業生物資源研究所 | 抗菌ペプチド及びこれを有効成分とする抗菌剤 |
| US6492326B1 (en) | 1999-04-19 | 2002-12-10 | The Procter & Gamble Company | Skin care compositions containing combination of skin care actives |
| DE10106852A1 (de) | 2001-02-14 | 2002-09-05 | T Luger | Entzündungshemmende Verbindungen |
| SE0300207D0 (sv) * | 2003-01-29 | 2003-01-29 | Karolinska Innovations Ab | New use and composition |
| AU2004246909B2 (en) * | 2003-06-19 | 2010-08-19 | Yeda Research & Development Co. Ltd. | Antimicrobial and anticancer lipopeptides |
| JP4256389B2 (ja) * | 2003-11-17 | 2009-04-22 | セダーマ | テトラペプチドとトリペプチドの混合物を含む組成物 |
| FR2870244B1 (fr) * | 2004-05-11 | 2011-01-07 | Centre Nat Rech Scient | Conjugues dipeptidiques antagonistes de l'alpha-msh |
| DE102004055541A1 (de) * | 2004-11-17 | 2006-05-18 | Henkel Kgaa | Kosmetische und dermatologische Zusammensetzungen zur Behandlung reifer Haut |
| US20100215726A1 (en) * | 2009-02-25 | 2010-08-26 | Peter Thomas Roth | Compositions for Diminishing the Appearance of Wrinkles |
| CN102329375A (zh) * | 2011-09-30 | 2012-01-25 | 中国药科大学 | 一组末端酰胺化的抗菌肽 |
-
2013
- 2013-03-07 AU AU2013235692A patent/AU2013235692B2/en not_active Ceased
- 2013-03-07 RU RU2014142038A patent/RU2627648C2/ru not_active IP Right Cessation
- 2013-03-07 ES ES13710751T patent/ES2729237T3/es active Active
- 2013-03-07 CN CN201710009878.5A patent/CN107080831A/zh active Pending
- 2013-03-07 MY MYPI2014002316A patent/MY163100A/en unknown
- 2013-03-07 CN CN201380014970.0A patent/CN104379177B/zh active Active
- 2013-03-07 EP EP13710751.2A patent/EP2827907B1/en active Active
- 2013-03-07 RU RU2017127273A patent/RU2017127273A/ru not_active Application Discontinuation
- 2013-03-07 WO PCT/US2013/029696 patent/WO2013142088A1/en not_active Ceased
- 2013-03-07 KR KR1020147028361A patent/KR20140136494A/ko not_active Ceased
- 2013-03-07 US US14/385,517 patent/US9278994B2/en active Active
- 2013-03-07 JP JP2015501713A patent/JP6261560B2/ja not_active Expired - Fee Related
- 2013-03-07 MX MX2014011290A patent/MX2014011290A/es unknown
- 2013-03-07 PL PL13710751T patent/PL2827907T3/pl unknown
- 2013-03-07 SG SG11201405244RA patent/SG11201405244RA/en unknown
- 2013-03-07 DK DK13710751.2T patent/DK2827907T3/da active
- 2013-03-07 CA CA2864179A patent/CA2864179A1/en not_active Abandoned
- 2013-03-07 SG SG10201607784VA patent/SG10201607784VA/en unknown
- 2013-03-19 TW TW102109748A patent/TWI541254B/zh not_active IP Right Cessation
- 2013-03-20 AR ARP130100903A patent/AR090439A1/es unknown
-
2014
- 2014-08-13 ZA ZA2014/05950A patent/ZA201405950B/en unknown
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