BR112015002726A8 - combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmaceutica - Google Patents

combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmaceutica

Info

Publication number
BR112015002726A8
BR112015002726A8 BR112015002726A BR112015002726A BR112015002726A8 BR 112015002726 A8 BR112015002726 A8 BR 112015002726A8 BR 112015002726 A BR112015002726 A BR 112015002726A BR 112015002726 A BR112015002726 A BR 112015002726A BR 112015002726 A8 BR112015002726 A8 BR 112015002726A8
Authority
BR
Brazil
Prior art keywords
combination
pharmaceutical composition
kit
pharmaceutical
composition
Prior art date
Application number
BR112015002726A
Other languages
English (en)
Other versions
BR112015002726B1 (pt
BR112015002726A2 (pt
Inventor
Obrecht Daniel
Bernardini Francesca
E Dale Glenn
Original Assignee
Polyphor Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyphor Ag filed Critical Polyphor Ag
Publication of BR112015002726A2 publication Critical patent/BR112015002726A2/pt
Publication of BR112015002726A8 publication Critical patent/BR112015002726A8/pt
Publication of BR112015002726B1 publication Critical patent/BR112015002726B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12Cyclic peptides with only normal peptide bonds in the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
BR112015002726-1A 2012-08-08 2013-08-07 Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica BR112015002726B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12005743 2012-08-08
EP12005743.5 2012-08-08
PCT/EP2013/066551 WO2014023766A1 (en) 2012-08-08 2013-08-07 Combinations with a backbone-cyclized peptide

Publications (3)

Publication Number Publication Date
BR112015002726A2 BR112015002726A2 (pt) 2017-07-04
BR112015002726A8 true BR112015002726A8 (pt) 2018-01-16
BR112015002726B1 BR112015002726B1 (pt) 2022-10-04

Family

ID=46796225

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015002726-1A BR112015002726B1 (pt) 2012-08-08 2013-08-07 Combinação, composição farmacêutica, kit, e, usos de uma combinação, e de uma composição farmacêutica

Country Status (26)

Country Link
US (1) US9814754B2 (pt)
EP (1) EP2882771B1 (pt)
JP (2) JP6486271B2 (pt)
KR (1) KR102142870B1 (pt)
CN (1) CN104684924B (pt)
AU (1) AU2013301576B2 (pt)
BR (1) BR112015002726B1 (pt)
CA (1) CA2887388C (pt)
CY (1) CY1120727T1 (pt)
DK (1) DK2882771T3 (pt)
EA (1) EA030524B1 (pt)
ES (1) ES2640289T3 (pt)
HK (1) HK1207868A1 (pt)
HR (1) HRP20171385T1 (pt)
HU (1) HUE036289T2 (pt)
IL (1) IL236696B (pt)
LT (1) LT2882771T (pt)
MX (2) MX366993B (pt)
NZ (1) NZ703723A (pt)
PL (1) PL2882771T3 (pt)
PT (1) PT2882771T (pt)
RS (1) RS56350B1 (pt)
SG (1) SG11201500130WA (pt)
SI (1) SI2882771T1 (pt)
WO (1) WO2014023766A1 (pt)
ZA (1) ZA201500277B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101479148B1 (ko) 2007-02-28 2015-01-05 폴리포 리미티드 주형 고정된 펩타이드 모방체
KR101692992B1 (ko) 2015-05-20 2017-01-17 연세대학교 산학협력단 고리형 펩타이드의 사전 활성화 합성방법 및 이에 따라 합성된 고리형 펩타이드
MX2023005982A (es) * 2020-11-23 2023-08-15 Spexis Ag Composiciones de un peptidomimetico de horquilla beta y formas de dosificacion en aerosol del mismo.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003232253A1 (en) * 2003-05-02 2004-11-23 Polyphor Ag Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity
WO2007079597A1 (en) * 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity
WO2010017273A2 (en) 2008-08-06 2010-02-11 Wyeth Tigecycline formulations

Also Published As

Publication number Publication date
AU2013301576A1 (en) 2015-02-05
JP2015524461A (ja) 2015-08-24
HUE036289T2 (hu) 2018-06-28
WO2014023766A1 (en) 2014-02-13
CN104684924B (zh) 2018-04-17
EA030524B1 (ru) 2018-08-31
IL236696A0 (en) 2015-02-26
MX366993B (es) 2019-08-02
US9814754B2 (en) 2017-11-14
CN104684924A (zh) 2015-06-03
LT2882771T (lt) 2017-09-25
NZ703723A (en) 2018-03-23
KR20150038611A (ko) 2015-04-08
MX2019002894A (es) 2019-07-04
BR112015002726B1 (pt) 2022-10-04
BR112015002726A2 (pt) 2017-07-04
ZA201500277B (en) 2015-12-23
HRP20171385T1 (hr) 2017-11-03
DK2882771T3 (en) 2017-09-25
CA2887388A1 (en) 2014-02-13
SI2882771T1 (sl) 2017-11-30
ES2640289T3 (es) 2017-11-02
MX2015001684A (es) 2015-04-10
US20150224168A1 (en) 2015-08-13
CA2887388C (en) 2021-02-16
JP6486271B2 (ja) 2019-03-20
KR102142870B1 (ko) 2020-08-11
EP2882771A1 (en) 2015-06-17
EP2882771B1 (en) 2017-06-14
IL236696B (en) 2019-06-30
AU2013301576B2 (en) 2017-10-19
HK1207868A1 (en) 2016-02-12
PL2882771T3 (pl) 2018-01-31
PT2882771T (pt) 2017-09-22
SG11201500130WA (en) 2015-03-30
CY1120727T1 (el) 2019-12-11
RS56350B1 (sr) 2017-12-29
EA201590350A1 (ru) 2015-07-30
JP2018109008A (ja) 2018-07-12

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/08/2013, OBSERVADAS AS CONDICOES LEGAIS