CU24163B1 - Composición farmacéutica oftalmológica tópica que contiene regorafenib - Google Patents
Composición farmacéutica oftalmológica tópica que contiene regorafenibInfo
- Publication number
- CU24163B1 CU24163B1 CU20130168A CU20130168A CU24163B1 CU 24163 B1 CU24163 B1 CU 24163B1 CU 20130168 A CU20130168 A CU 20130168A CU 20130168 A CU20130168 A CU 20130168A CU 24163 B1 CU24163 B1 CU 24163B1
- Authority
- CU
- Cuba
- Prior art keywords
- typical
- pharmaceutical composition
- composition containing
- ophthalmological pharmaceutical
- containing regorafenib
- Prior art date
Links
- 239000002138 L01XE21 - Regorafenib Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229960004836 regorafenib Drugs 0.000 title 1
- ZOPOQLDXFHBOIH-UHFFFAOYSA-N regorafenib hydrate Chemical compound O.C1=NC(C(=O)NC)=CC(OC=2C=C(F)C(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 ZOPOQLDXFHBOIH-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11171719 | 2011-06-28 | ||
| EP12155281 | 2012-02-14 | ||
| PCT/EP2012/062365 WO2013000917A1 (en) | 2011-06-28 | 2012-06-26 | Topical ophthalmological pharmaceutical composition containing regorafenib |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20130168A7 CU20130168A7 (es) | 2014-04-24 |
| CU24163B1 true CU24163B1 (es) | 2016-03-31 |
Family
ID=46456546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20130168A CU24163B1 (es) | 2011-06-28 | 2012-06-26 | Composición farmacéutica oftalmológica tópica que contiene regorafenib |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20140296301A1 (es) |
| EP (1) | EP2726059A1 (es) |
| JP (1) | JP5998213B2 (es) |
| KR (1) | KR20140048218A (es) |
| CN (1) | CN103889399A (es) |
| AP (1) | AP2013007335A0 (es) |
| AR (1) | AR086800A1 (es) |
| AU (1) | AU2012277905A1 (es) |
| BR (1) | BR112013033831A2 (es) |
| CA (1) | CA2840329A1 (es) |
| CL (1) | CL2013003700A1 (es) |
| CO (1) | CO6920289A2 (es) |
| CR (1) | CR20130693A (es) |
| CU (1) | CU24163B1 (es) |
| DO (1) | DOP2013000314A (es) |
| EA (1) | EA201400064A1 (es) |
| EC (1) | ECSP13013106A (es) |
| GT (1) | GT201300322A (es) |
| HK (1) | HK1197176A1 (es) |
| MX (1) | MX2013015287A (es) |
| PE (1) | PE20141031A1 (es) |
| TN (1) | TN2013000533A1 (es) |
| UY (1) | UY34166A (es) |
| WO (1) | WO2013000917A1 (es) |
| ZA (1) | ZA201400646B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ553804A (en) | 2004-09-29 | 2010-07-30 | Bayer Schering Pharma Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| UY35183A (es) * | 2012-12-21 | 2014-07-31 | Bayer Healthcare Llc | Composición farmacéutica oftalmológica tópica que contiene regorafenib |
| WO2015011659A1 (en) * | 2013-07-24 | 2015-01-29 | Dr. Reddys Laboratories Limited | Crystalline polymorphic forms of regorafenib and processes for the preparation of polymorph i of regorafenib |
| CN103923000A (zh) * | 2014-01-29 | 2014-07-16 | 苏州晶云药物科技有限公司 | 几种新晶型及其制备方法 |
| CN104546776B (zh) * | 2015-02-10 | 2017-08-22 | 杭州朱养心药业有限公司 | 瑞戈非尼片剂药物组合物和制法 |
| WO2016200688A1 (en) * | 2015-06-06 | 2016-12-15 | Cloudbreak Therapeutics, Llc | Compositions and methods for treating pterygium |
| KR102657707B1 (ko) | 2016-06-02 | 2024-04-15 | 에이디에스 테라퓨틱스 엘엘씨 | 녹내장 수술 성공을 개선하기 위해 닌테다닙을 사용하는 조성물 및 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2732222B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour le traitement des prurits et des dysesthesies oculaires et palpebraux |
| AU2003232828B2 (en) * | 2002-05-28 | 2010-06-24 | Takeda Gmbh | Topically applicable pharmaceutical preparation |
| JP4777887B2 (ja) | 2003-07-23 | 2011-09-21 | バイエル、ファーマシューテイカルズ、コーポレイション | 病気および状態の処置および防止のためのフロロ置換オメガカルボキシアリールジフェニル尿素 |
| DK1885336T3 (da) | 2005-05-10 | 2009-05-25 | Alcon Inc | Suspensionsformuleringer, der omfatter et aktivt princip, et overfladeaktivt poloxamer- eller meroxapolmiddel og en glycol, samt deres anvendelse til fremstilling af et medikament til behandling af öjenlidelser |
| AU2006254825A1 (en) | 2005-06-08 | 2006-12-14 | Targegen, Inc. | Methods and compositions for the treatment of ocular disorders |
| WO2007064752A2 (en) | 2005-11-29 | 2007-06-07 | Smithkline Beecham Corporation | Treatment of ocular neovascular disorders such as macular degeneration, angiod streaks, uveitis and macular edema |
| WO2007068382A1 (en) * | 2005-12-15 | 2007-06-21 | Bayer Healthcare Ag | Diaryl urea for treating inflammatory skin. eye and/or ear diseases |
| US20070149593A1 (en) | 2005-12-23 | 2007-06-28 | Alcon, Inc. | PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
| WO2008027341A2 (en) | 2006-08-30 | 2008-03-06 | Merck & Co., Inc. | Topical ophthalmic formulations |
| AR062927A1 (es) | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
| JP2008308488A (ja) * | 2007-05-11 | 2008-12-25 | Santen Pharmaceut Co Ltd | 非麦角系の選択的ｄ２受容体アゴニストを有効成分として含有する後眼部疾患の予防又は治療剤 |
| DE102007055341A1 (de) * | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| CA2760687A1 (en) | 2009-05-01 | 2010-11-04 | Ophthotech Corporation | Methods for treating or preventing ophthalmological diseases |
| EA201190337A1 (ru) | 2009-07-16 | 2012-06-29 | Глаксо Вэллкам Мэньюфэкчуринг Пти Лтд. | Способ лечения |
-
2012
- 2012-06-26 CA CA2840329A patent/CA2840329A1/en not_active Abandoned
- 2012-06-26 EA EA201400064A patent/EA201400064A1/ru unknown
- 2012-06-26 MX MX2013015287A patent/MX2013015287A/es not_active Application Discontinuation
- 2012-06-26 AP AP2013007335A patent/AP2013007335A0/xx unknown
- 2012-06-26 KR KR1020147002095A patent/KR20140048218A/ko not_active Application Discontinuation
- 2012-06-26 JP JP2014517661A patent/JP5998213B2/ja not_active Expired - Fee Related
- 2012-06-26 WO PCT/EP2012/062365 patent/WO2013000917A1/en active Application Filing
- 2012-06-26 AU AU2012277905A patent/AU2012277905A1/en not_active Abandoned
- 2012-06-26 BR BR112013033831A patent/BR112013033831A2/pt not_active IP Right Cessation
- 2012-06-26 PE PE2013002872A patent/PE20141031A1/es not_active Application Discontinuation
- 2012-06-26 CN CN201280042504.9A patent/CN103889399A/zh active Pending
- 2012-06-26 CU CU20130168A patent/CU24163B1/es active IP Right Grant
- 2012-06-26 EP EP12731396.3A patent/EP2726059A1/en not_active Withdrawn
- 2012-06-26 US US14/128,356 patent/US20140296301A1/en not_active Abandoned
- 2012-06-27 UY UY0001034166A patent/UY34166A/es not_active Application Discontinuation
- 2012-06-28 AR ARP120102339A patent/AR086800A1/es active Pending
-
2013
- 2013-12-20 CR CR20130693A patent/CR20130693A/es unknown
- 2013-12-23 CL CL2013003700A patent/CL2013003700A1/es unknown
- 2013-12-23 GT GT201300322A patent/GT201300322A/es unknown
- 2013-12-24 EC EC2013013106A patent/ECSP13013106A/es unknown
- 2013-12-26 DO DO2013000314A patent/DOP2013000314A/es unknown
- 2013-12-26 CO CO13300167A patent/CO6920289A2/es not_active Application Discontinuation
- 2013-12-27 TN TNP2013000533A patent/TN2013000533A1/fr unknown
-
2014
- 2014-01-27 ZA ZA2014/00646A patent/ZA201400646B/en unknown
- 2014-10-22 HK HK14110517A patent/HK1197176A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5998213B2 (ja) | 2016-09-28 |
| DOP2013000314A (es) | 2014-04-15 |
| BR112013033831A2 (pt) | 2017-02-14 |
| AP2013007335A0 (en) | 2013-12-31 |
| TN2013000533A1 (en) | 2015-03-30 |
| CL2013003700A1 (es) | 2014-07-18 |
| EP2726059A1 (en) | 2014-05-07 |
| AR086800A1 (es) | 2014-01-22 |
| US20140296301A1 (en) | 2014-10-02 |
| AU2012277905A8 (en) | 2014-01-30 |
| CO6920289A2 (es) | 2014-04-10 |
| ECSP13013106A (es) | 2014-01-31 |
| CR20130693A (es) | 2016-05-02 |
| UY34166A (es) | 2013-01-31 |
| ZA201400646B (en) | 2015-11-25 |
| NZ619229A (en) | 2016-04-29 |
| GT201300322A (es) | 2014-11-13 |
| KR20140048218A (ko) | 2014-04-23 |
| CU20130168A7 (es) | 2014-04-24 |
| HK1197176A1 (en) | 2015-01-09 |
| CA2840329A1 (en) | 2013-01-03 |
| MX2013015287A (es) | 2014-03-31 |
| CN103889399A (zh) | 2014-06-25 |
| JP2014518233A (ja) | 2014-07-28 |
| WO2013000917A1 (en) | 2013-01-03 |
| PE20141031A1 (es) | 2014-08-21 |
| EA201400064A1 (ru) | 2014-05-30 |
| AU2012277905A1 (en) | 2014-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |