HK1197176A1 - Topical ophthalmological pharmaceutical composition containing regorafenib - Google Patents
Topical ophthalmological pharmaceutical composition containing regorafenibInfo
- Publication number
- HK1197176A1 HK1197176A1 HK14110517A HK14110517A HK1197176A1 HK 1197176 A1 HK1197176 A1 HK 1197176A1 HK 14110517 A HK14110517 A HK 14110517A HK 14110517 A HK14110517 A HK 14110517A HK 1197176 A1 HK1197176 A1 HK 1197176A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical composition
- composition containing
- ophthalmological pharmaceutical
- topical ophthalmological
- containing regorafenib
- Prior art date
Links
- 239000002138 L01XE21 - Regorafenib Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- FNHKPVJBJVTLMP-UHFFFAOYSA-N regorafenib Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=C(F)C(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 FNHKPVJBJVTLMP-UHFFFAOYSA-N 0.000 title 1
- 229960004836 regorafenib Drugs 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11171719 | 2011-06-28 | ||
| EP12155281 | 2012-02-14 | ||
| PCT/EP2012/062365 WO2013000917A1 (en) | 2011-06-28 | 2012-06-26 | Topical ophthalmological pharmaceutical composition containing regorafenib |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1197176A1 true HK1197176A1 (en) | 2015-01-09 |
Family
ID=46456546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14110517A HK1197176A1 (en) | 2011-06-28 | 2014-10-22 | Topical ophthalmological pharmaceutical composition containing regorafenib |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20140296301A1 (es) |
| EP (1) | EP2726059A1 (es) |
| JP (1) | JP5998213B2 (es) |
| KR (1) | KR20140048218A (es) |
| CN (1) | CN103889399A (es) |
| AP (1) | AP2013007335A0 (es) |
| AR (1) | AR086800A1 (es) |
| AU (1) | AU2012277905A1 (es) |
| BR (1) | BR112013033831A2 (es) |
| CA (1) | CA2840329A1 (es) |
| CL (1) | CL2013003700A1 (es) |
| CO (1) | CO6920289A2 (es) |
| CR (1) | CR20130693A (es) |
| CU (1) | CU24163B1 (es) |
| DO (1) | DOP2013000314A (es) |
| EA (1) | EA201400064A1 (es) |
| EC (1) | ECSP13013106A (es) |
| GT (1) | GT201300322A (es) |
| HK (1) | HK1197176A1 (es) |
| MX (1) | MX2013015287A (es) |
| PE (1) | PE20141031A1 (es) |
| TN (1) | TN2013000533A1 (es) |
| UY (1) | UY34166A (es) |
| WO (1) | WO2013000917A1 (es) |
| ZA (1) | ZA201400646B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5215666B2 (ja) | 2004-09-29 | 2013-06-19 | バイエル・ファルマ・アクチェンゲゼルシャフト | Ｂａｙ４３−９００６トシレートの熱力学的に安定な形態 |
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| UY35183A (es) * | 2012-12-21 | 2014-07-31 | Bayer Healthcare Llc | Composición farmacéutica oftalmológica tópica que contiene regorafenib |
| WO2015011659A1 (en) * | 2013-07-24 | 2015-01-29 | Dr. Reddys Laboratories Limited | Crystalline polymorphic forms of regorafenib and processes for the preparation of polymorph i of regorafenib |
| CN103923000A (zh) * | 2014-01-29 | 2014-07-16 | 苏州晶云药物科技有限公司 | 几种新晶型及其制备方法 |
| CN104546776B (zh) * | 2015-02-10 | 2017-08-22 | 杭州朱养心药业有限公司 | 瑞戈非尼片剂药物组合物和制法 |
| CN114010787A (zh) * | 2015-06-06 | 2022-02-08 | 拨云生物医药科技(广州)有限公司 | 用于治疗翼状胬肉的组合物和方法 |
| MX2018014868A (es) | 2016-06-02 | 2019-09-13 | Cloudbreak Therapeutics Llc | Composiciones y metodos de uso de nintedanib para mejorar el exito de la cirugia del glaucoma. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2732222B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour le traitement des prurits et des dysesthesies oculaires et palpebraux |
| EP1511516B1 (en) * | 2002-05-28 | 2008-12-17 | Nycomed GmbH | Topically applicable pharmaceutical preparation |
| NZ580384A (en) * | 2003-07-23 | 2011-03-31 | Bayer Pharmaceuticals Corp | 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide and metabolites for the treatment and prevention of diseases and conditions |
| PL1885336T3 (pl) | 2005-05-10 | 2009-08-31 | Alcon Inc | Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu |
| EP1893216A4 (en) | 2005-06-08 | 2012-08-08 | Targegen Inc | METHOD AND COMPOSITIONS FOR THE TREATMENT OF EYE DISEASES |
| US20080293691A1 (en) | 2005-11-29 | 2008-11-27 | Smithkline Beecham Corporation | Treatment Method |
| EP1962828A1 (en) * | 2005-12-15 | 2008-09-03 | Bayer HealthCare AG | Diaryl urea for treating inflammatory skin, eye and/or ear diseases |
| WO2007076358A1 (en) | 2005-12-23 | 2007-07-05 | Alcon, Inc. | PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
| WO2008027341A2 (en) | 2006-08-30 | 2008-03-06 | Merck & Co., Inc. | Topical ophthalmic formulations |
| AR062927A1 (es) * | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
| JP2008308489A (ja) * | 2007-05-11 | 2008-12-25 | Santen Pharmaceut Co Ltd | ロピニロール又はその塩を有効成分として含有する後眼部疾患の予防又は治療剤 |
| DE102007055341A1 (de) * | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| EP3165606A1 (en) | 2009-05-01 | 2017-05-10 | Ophthotech Corporation | Methods for treating or preventing ophthalmological diseases |
| CN102573477A (zh) | 2009-07-16 | 2012-07-11 | 葛兰素惠尔康制造业私人有限公司 | 治疗方法 |
-
2012
- 2012-06-26 JP JP2014517661A patent/JP5998213B2/ja not_active Expired - Fee Related
- 2012-06-26 EP EP12731396.3A patent/EP2726059A1/en not_active Withdrawn
- 2012-06-26 PE PE2013002872A patent/PE20141031A1/es not_active Application Discontinuation
- 2012-06-26 KR KR1020147002095A patent/KR20140048218A/ko not_active Application Discontinuation
- 2012-06-26 AU AU2012277905A patent/AU2012277905A1/en not_active Abandoned
- 2012-06-26 BR BR112013033831A patent/BR112013033831A2/pt not_active IP Right Cessation
- 2012-06-26 WO PCT/EP2012/062365 patent/WO2013000917A1/en active Application Filing
- 2012-06-26 CA CA2840329A patent/CA2840329A1/en not_active Abandoned
- 2012-06-26 AP AP2013007335A patent/AP2013007335A0/xx unknown
- 2012-06-26 CU CU20130168A patent/CU24163B1/es active IP Right Grant
- 2012-06-26 MX MX2013015287A patent/MX2013015287A/es not_active Application Discontinuation
- 2012-06-26 CN CN201280042504.9A patent/CN103889399A/zh active Pending
- 2012-06-26 EA EA201400064A patent/EA201400064A1/ru unknown
- 2012-06-26 US US14/128,356 patent/US20140296301A1/en not_active Abandoned
- 2012-06-27 UY UY0001034166A patent/UY34166A/es not_active Application Discontinuation
- 2012-06-28 AR ARP120102339A patent/AR086800A1/es active Pending
-
2013
- 2013-12-20 CR CR20130693A patent/CR20130693A/es unknown
- 2013-12-23 CL CL2013003700A patent/CL2013003700A1/es unknown
- 2013-12-23 GT GT201300322A patent/GT201300322A/es unknown
- 2013-12-24 EC EC2013013106A patent/ECSP13013106A/es unknown
- 2013-12-26 CO CO13300167A patent/CO6920289A2/es not_active Application Discontinuation
- 2013-12-26 DO DO2013000314A patent/DOP2013000314A/es unknown
- 2013-12-27 TN TNP2013000533A patent/TN2013000533A1/fr unknown
-
2014
- 2014-01-27 ZA ZA2014/00646A patent/ZA201400646B/en unknown
- 2014-10-22 HK HK14110517A patent/HK1197176A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CU24163B1 (es) | 2016-03-31 |
| KR20140048218A (ko) | 2014-04-23 |
| EP2726059A1 (en) | 2014-05-07 |
| UY34166A (es) | 2013-01-31 |
| BR112013033831A2 (pt) | 2017-02-14 |
| CO6920289A2 (es) | 2014-04-10 |
| ECSP13013106A (es) | 2014-01-31 |
| AU2012277905A1 (en) | 2014-01-16 |
| US20140296301A1 (en) | 2014-10-02 |
| JP5998213B2 (ja) | 2016-09-28 |
| AP2013007335A0 (en) | 2013-12-31 |
| DOP2013000314A (es) | 2014-04-15 |
| ZA201400646B (en) | 2015-11-25 |
| AU2012277905A8 (en) | 2014-01-30 |
| GT201300322A (es) | 2014-11-13 |
| JP2014518233A (ja) | 2014-07-28 |
| PE20141031A1 (es) | 2014-08-21 |
| CU20130168A7 (es) | 2014-04-24 |
| WO2013000917A1 (en) | 2013-01-03 |
| AR086800A1 (es) | 2014-01-22 |
| NZ619229A (en) | 2016-04-29 |
| CN103889399A (zh) | 2014-06-25 |
| CR20130693A (es) | 2016-05-02 |
| EA201400064A1 (ru) | 2014-05-30 |
| CA2840329A1 (en) | 2013-01-03 |
| TN2013000533A1 (en) | 2015-03-30 |
| CL2013003700A1 (es) | 2014-07-18 |
| MX2013015287A (es) | 2014-03-31 |
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