JP2015506343A5 - - Google Patents
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- Publication number
- JP2015506343A5 JP2015506343A5 JP2014548213A JP2014548213A JP2015506343A5 JP 2015506343 A5 JP2015506343 A5 JP 2015506343A5 JP 2014548213 A JP2014548213 A JP 2014548213A JP 2014548213 A JP2014548213 A JP 2014548213A JP 2015506343 A5 JP2015506343 A5 JP 2015506343A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- process according
- carried out
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- VZWHHXZBHHKWAP-QYNIEUIISA-N O[C@@H](COc1cccc(C(F)(F)F)c1)/C=C/[C@H]([C@@H](C1)[C@H](C2)OC1=O)[C@@H]2OC(c(cc1)ccc1-c1ccccc1)=O Chemical compound O[C@@H](COc1cccc(C(F)(F)F)c1)/C=C/[C@H]([C@@H](C1)[C@H](C2)OC1=O)[C@@H]2OC(c(cc1)ccc1-c1ccccc1)=O VZWHHXZBHHKWAP-QYNIEUIISA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU1100701A HU231203B1 (hu) | 2011-12-21 | 2011-12-21 | Új eljárás travoprost előállítására |
| HUP1100701 | 2011-12-21 | ||
| PCT/HU2012/000132 WO2013093528A1 (en) | 2011-12-21 | 2012-12-10 | Process for the preparation of travoprost |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015506343A JP2015506343A (ja) | 2015-03-02 |
| JP2015506343A5 true JP2015506343A5 (enExample) | 2015-12-03 |
| JP6174040B2 JP6174040B2 (ja) | 2017-08-02 |
Family
ID=89990547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548213A Active JP6174040B2 (ja) | 2011-12-21 | 2012-12-10 | トラボプロストの調製方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9212125B2 (enExample) |
| EP (1) | EP2802562B1 (enExample) |
| JP (1) | JP6174040B2 (enExample) |
| KR (1) | KR102027889B1 (enExample) |
| CN (1) | CN103998423B (enExample) |
| BR (1) | BR112014014060A2 (enExample) |
| CA (1) | CA2859923C (enExample) |
| ES (1) | ES2721662T3 (enExample) |
| HU (1) | HU231203B1 (enExample) |
| IL (1) | IL232625B (enExample) |
| IN (1) | IN2014CN03482A (enExample) |
| MX (1) | MX2014007684A (enExample) |
| PL (1) | PL2802562T3 (enExample) |
| RU (1) | RU2631316C2 (enExample) |
| TR (1) | TR201905687T4 (enExample) |
| TW (1) | TWI640500B (enExample) |
| WO (1) | WO2013093528A1 (enExample) |
| ZA (1) | ZA201404440B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106278982B (zh) * | 2011-06-02 | 2019-06-14 | 奇诺因私人有限公司 | 用于制备前列腺素酰胺的新的方法 |
| US9115109B2 (en) * | 2013-08-15 | 2015-08-25 | Chirogate International Inc. | Processes and intermediates for the preparations of isomer free prostaglandins |
| HU231214B1 (hu) * | 2014-03-13 | 2021-11-29 | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. | Új eljárás nagytisztaságú prosztaglandinok előállítására |
| WO2017062770A1 (en) | 2015-10-08 | 2017-04-13 | Silverberg Noah | Punctal plug and bioadhesives |
| EP3950672A4 (en) * | 2019-03-27 | 2023-01-11 | Kyowa Pharma Chemical Co., Ltd. | Method for producing pkrostaglandin |
| HU231350B1 (hu) * | 2019-12-18 | 2023-01-28 | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt | Eljárás királis prosztaglandin-enol intermedier előállítására, és az eljárásban hasznos köztitermék vegyületek |
| WO2021158968A1 (en) | 2020-02-06 | 2021-08-12 | Ocular Therapeutix, Inc. | Compositions and methods for treating ocular diseases |
| CA3177005A1 (en) | 2020-04-27 | 2021-11-04 | Michael Goldstein | Methods of treating allergic conjunctivitis |
| ES3047661T3 (en) * | 2020-12-23 | 2025-12-04 | Kyowa Pharma Chemical Co Ltd | Method for separating geometrical isomer |
| CN114671906B (zh) * | 2020-12-24 | 2024-03-15 | 武汉武药制药有限公司 | 制备曲伏前列素中间体的方法 |
| CN116947725B (zh) * | 2022-04-14 | 2026-03-27 | 广州楷石医药有限公司 | 曲伏前列素的合成方法 |
| CN115806517A (zh) * | 2022-12-21 | 2023-03-17 | 上海彩迩文生化科技有限公司 | 一种高纯度地诺前列腺素的制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2328131C3 (de) * | 1973-05-30 | 1986-11-13 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neues Verfahren zur Herstellung von Prostaglandin-F↓2↓↓α↓ und seinen Analogen |
| HU184948B (en) * | 1981-04-14 | 1984-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 5-substituted 4-oxo-pgi down 1 derivatives |
| HU190007B (en) | 1982-05-06 | 1986-08-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for producing new aromatic prostacylin analogues |
| CS239696B1 (cs) * | 1984-05-03 | 1986-01-16 | Jiri Hajek | Způsob dělení 15S-a 15R-isomerů 4-/4-/substituovaných X-fenoxy/-3-hydroxy-1butenyí/hexahydro-5-hydroxy- -2H-cyklopenta[b]furan-2-onů |
| HU212570B (en) | 1991-06-24 | 1996-08-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 13,14-dihydro-15(r)-17-phenyl-18,19,20-trinor-pgf2alfa-isopropylester |
| US5510383A (en) | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| US7166730B2 (en) * | 2000-01-27 | 2007-01-23 | Fine Tech Laboratories, Ltd | Process for the preparation of prostaglandin derivatives |
| GB0112699D0 (en) * | 2001-05-24 | 2001-07-18 | Resolution Chemicals Ltd | Process for the preparation of prostglandins and analogues thereof |
| GB0329379D0 (en) * | 2003-12-19 | 2004-01-21 | Johnson Matthey Plc | Prostaglandin synthesis |
| ES2767136T3 (es) * | 2004-01-05 | 2020-06-16 | Nicox Sa | Derivados de prostaglandinas |
| EP2143712A1 (en) * | 2008-07-10 | 2010-01-13 | Sandoz AG | Improved Process for the Production of Prostaglandins and Prostaglandin Analogs |
| IT1393112B1 (it) * | 2009-02-27 | 2012-04-11 | Sifavitor S R L | Procedimento per la preparazione di derivati di prostaglandine |
| EP2488508A4 (en) * | 2009-10-16 | 2013-04-24 | Cayman Chemical Co Inc | PROCESS FOR THE PREPARATION OF PROSTAGLANDINS OF THE F-SERIES |
| WO2011055377A1 (en) | 2009-11-05 | 2011-05-12 | Biocon Limited | A novel process for the preparation of prostaglandins and intermediates thereof |
| EP2495235B1 (en) | 2011-03-04 | 2015-08-05 | Newchem S.p.A. | Process for the synthesis of prostaglandins and intermediates thereof |
| CN106278982B (zh) | 2011-06-02 | 2019-06-14 | 奇诺因私人有限公司 | 用于制备前列腺素酰胺的新的方法 |
-
2011
- 2011-12-21 HU HU1100701A patent/HU231203B1/hu unknown
-
2012
- 2012-12-10 IN IN3482CHN2014 patent/IN2014CN03482A/en unknown
- 2012-12-10 TR TR2019/05687T patent/TR201905687T4/tr unknown
- 2012-12-10 CA CA2859923A patent/CA2859923C/en active Active
- 2012-12-10 BR BR112014014060A patent/BR112014014060A2/pt not_active Application Discontinuation
- 2012-12-10 WO PCT/HU2012/000132 patent/WO2013093528A1/en not_active Ceased
- 2012-12-10 KR KR1020147020311A patent/KR102027889B1/ko active Active
- 2012-12-10 CN CN201280063528.2A patent/CN103998423B/zh active Active
- 2012-12-10 PL PL12816098T patent/PL2802562T3/pl unknown
- 2012-12-10 MX MX2014007684A patent/MX2014007684A/es unknown
- 2012-12-10 ES ES12816098T patent/ES2721662T3/es active Active
- 2012-12-10 US US14/367,317 patent/US9212125B2/en active Active
- 2012-12-10 EP EP12816098.3A patent/EP2802562B1/en active Active
- 2012-12-10 JP JP2014548213A patent/JP6174040B2/ja active Active
- 2012-12-10 RU RU2014129492A patent/RU2631316C2/ru active
- 2012-12-20 TW TW101148584A patent/TWI640500B/zh active
-
2014
- 2014-05-14 IL IL232625A patent/IL232625B/en active IP Right Grant
- 2014-06-17 ZA ZA2014/04440A patent/ZA201404440B/en unknown
-
2015
- 2015-10-30 US US14/928,629 patent/US20160137621A1/en not_active Abandoned
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