JP2015504307A - 特発性肺線維症を診断および治療する方法 - Google Patents

特発性肺線維症を診断および治療する方法 Download PDF

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JP2015504307A
JP2015504307A JP2014542588A JP2014542588A JP2015504307A JP 2015504307 A JP2015504307 A JP 2015504307A JP 2014542588 A JP2014542588 A JP 2014542588A JP 2014542588 A JP2014542588 A JP 2014542588A JP 2015504307 A JP2015504307 A JP 2015504307A
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mir
micrornas
sequence
ipf
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JP2015504307A5 (enExample
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カール コッセン，
カール コッセン，
シャルレーン リム，
シャルレーン リム，
シャオリ チン，
シャオリ チン，
ウイリアムソン ジーグラー ブラッドフォード，
ウイリアムソン ジーグラー ブラッドフォード，
スコット ディー． セイワート，
スコット ディー． セイワート，
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インターミューン， インコーポレイテッド
インターミューン， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
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  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Nuclear Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014542588A 2011-11-22 2012-11-21 特発性肺線維症を診断および治療する方法 Pending JP2015504307A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161562770P 2011-11-22 2011-11-22
US61/562,770 2011-11-22
US201261648548P 2012-05-17 2012-05-17
US61/648,548 2012-05-17
PCT/US2012/066221 WO2013078283A1 (en) 2011-11-22 2012-11-21 Methods of diagnosing and treating idiopathic pulmonary fibrosis

Publications (2)

Publication Number Publication Date
JP2015504307A true JP2015504307A (ja) 2015-02-12
JP2015504307A5 JP2015504307A5 (enExample) 2016-01-21

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JP2014542588A Pending JP2015504307A (ja) 2011-11-22 2012-11-21 特発性肺線維症を診断および治療する方法

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US (1) US20130150426A1 (enExample)
EP (1) EP2783016A1 (enExample)
JP (1) JP2015504307A (enExample)
CN (1) CN103987858A (enExample)
AU (1) AU2012340698A1 (enExample)
BR (1) BR112014012288A2 (enExample)
CA (1) CA2853136A1 (enExample)
EA (1) EA201491019A1 (enExample)
HK (2) HK1201299A1 (enExample)
MX (1) MX2014006130A (enExample)
WO (1) WO2013078283A1 (enExample)

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JP2017143810A (ja) * 2016-02-19 2017-08-24 学校法人慶應義塾 抗酸菌症又は抗酸菌感染のバイオマーカー
JP2021129513A (ja) * 2020-02-19 2021-09-09 国立医薬品食品衛生研究所長 びまん性肺胞障害型薬剤性間質性肺炎のｍｉＲＮＡ診断バイオマーカー

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US10119135B2 (en) 2012-05-22 2018-11-06 Ruprecht-Karls-Universität Heidelberg Therapeutic micro RNA targets in chronic pulmonary diseases
CN104560991B (zh) * 2013-10-10 2021-02-26 复旦大学附属妇产科医院 用于防治人乳头瘤病毒感染和宫颈癌的微小rna
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CN105132525B (zh) * 2014-05-29 2018-11-09 中国医学科学院基础医学研究所 miRNA分子在精神分裂症的诊断和预后中的用途
EP2957634A1 (en) * 2014-06-20 2015-12-23 Consejo Superior De Investigaciones Científicas Compounds for prevention and/or treatment of fibrotic diseases
RU2712511C2 (ru) 2014-09-08 2020-01-29 Мираген Терапеутикс, Инк. Миметики mir-29 и пути их применения
WO2016054094A1 (en) * 2014-09-30 2016-04-07 Research Institute At Nationwide Children's Hospital Compositions and methods for treating hepatic fibrosis
CN112063714A (zh) * 2014-10-28 2020-12-11 广州复能基因有限公司 一种与结直肠癌相关的miRNA及其应用
CN104450707B (zh) * 2014-12-25 2017-08-29 厦门大学 一种血清miRNA生物标志物的应用
CN104694542A (zh) * 2015-03-19 2015-06-10 中国人民解放军第四军医大学 一种促进组织工程骨血管化的 microRNA 及其应用
CN105079808B (zh) * 2015-05-22 2018-04-03 重庆医科大学 miR590的用途及其相关药物
WO2016205226A1 (en) * 2015-06-15 2016-12-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for diagnosing and treating affective disorders
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CN105106972A (zh) * 2015-08-13 2015-12-02 常州市第一人民医院 miR-338-5p及靶向作用于miR-338-5p核酸制剂的新用途
CN105169393B (zh) * 2015-08-31 2018-07-03 北京泱深生物信息技术有限公司 miRNA-548a-3p抗急性髓系白血病中的应用
US11180810B2 (en) 2015-09-29 2021-11-23 Research Institute At Nationwide Children's Hospital Methods for detecting hepatic fibrosis and responsiveness to therapy
CN106011303B (zh) * 2016-08-08 2019-05-24 南京市妇幼保健院 一种与儿童肥胖相关的血清或血浆miRNA标志物及其应用
WO2018170622A1 (zh) * 2017-03-18 2018-09-27 深圳市博奥康生物科技有限公司 一种同步下调微小rna-152和微小rna-185表达的方法
WO2018170652A1 (zh) * 2017-03-19 2018-09-27 深圳市博奥康生物科技有限公司 多重敲低三种miRNA的Tud RNA及其应用
CN107236799B (zh) * 2017-06-15 2020-06-09 昆明医科大学第六附属医院 一种肾纤维化miRNA标记物
CN108186564B (zh) * 2018-01-03 2020-06-02 上海市肿瘤研究所 一种肿瘤微环境响应型基因纳米胶束及其制备方法和应用
CN108611414A (zh) * 2018-04-26 2018-10-02 北京工业大学 新的靶向肿瘤微环境与肺癌干细胞相互作用的miRNA的检测及应用
CN109486911A (zh) * 2018-11-28 2019-03-19 上海纳米技术及应用国家工程研究中心有限公司 基于滚环扩增和DNA折纸术检测microRNAs的方法
CN109825575A (zh) * 2019-04-08 2019-05-31 首都医科大学附属北京胸科医院 辅助诊断结核病的miRNA标志物及其应用
CN110055322A (zh) * 2019-05-12 2019-07-26 青岛大学 用于急性心肌梗死诊断的循环miRNA标志物及其应用
HUE070614T2 (hu) * 2019-06-14 2025-06-28 Novo Nordisk As Szívelégtelenség és fibrózis kezelése humán alanyokon
WO2021009317A1 (en) 2019-07-16 2021-01-21 Université de Liège Extracellular vesicles containing mir-142-3p to treat fibrosing diseases

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017143810A (ja) * 2016-02-19 2017-08-24 学校法人慶應義塾 抗酸菌症又は抗酸菌感染のバイオマーカー
JP2021129513A (ja) * 2020-02-19 2021-09-09 国立医薬品食品衛生研究所長 びまん性肺胞障害型薬剤性間質性肺炎のｍｉＲＮＡ診断バイオマーカー
JP7392224B2 (ja) 2020-02-19 2023-12-06 国立医薬品食品衛生研究所長 びまん性肺胞傷害型薬剤性間質性肺炎のｍｉＲＮＡ診断バイオマーカー

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EA201491019A1 (ru) 2014-08-29
AU2012340698A1 (en) 2014-04-24
EP2783016A1 (en) 2014-10-01
CN103987858A (zh) 2014-08-13
US20130150426A1 (en) 2013-06-13
MX2014006130A (es) 2015-04-13
HK1201298A1 (en) 2015-08-28
BR112014012288A2 (pt) 2017-05-23
CA2853136A1 (en) 2013-05-30
WO2013078283A1 (en) 2013-05-30
HK1201299A1 (en) 2015-08-28

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