CA2853136A1 - Methods of diagnosing and treating idiopathic pulmonary fibrosis - Google Patents
Methods of diagnosing and treating idiopathic pulmonary fibrosis Download PDFInfo
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- CA2853136A1 CA2853136A1 CA2853136A CA2853136A CA2853136A1 CA 2853136 A1 CA2853136 A1 CA 2853136A1 CA 2853136 A CA2853136 A CA 2853136A CA 2853136 A CA2853136 A CA 2853136A CA 2853136 A1 CA2853136 A1 CA 2853136A1
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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| PCT/US2012/066221 WO2013078283A1 (en) | 2011-11-22 | 2012-11-21 | Methods of diagnosing and treating idiopathic pulmonary fibrosis |
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| CN104560991B (zh) * | 2013-10-10 | 2021-02-26 | 复旦大学附属妇产科医院 | 用于防治人乳头瘤病毒感染和宫颈癌的微小rna |
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| US20170226507A1 (en) * | 2014-05-05 | 2017-08-10 | The Brigham And Women's Hospital, Inc. | Coordinate control of pathogenic signaling by the mir-130/301 family in pulmonary hypertension and fibroproliferative diseases |
| CN105132525B (zh) * | 2014-05-29 | 2018-11-09 | 中国医学科学院基础医学研究所 | miRNA分子在精神分裂症的诊断和预后中的用途 |
| EP2957634A1 (en) * | 2014-06-20 | 2015-12-23 | Consejo Superior De Investigaciones Científicas | Compounds for prevention and/or treatment of fibrotic diseases |
| RU2712511C2 (ru) | 2014-09-08 | 2020-01-29 | Мираген Терапеутикс, Инк. | Миметики mir-29 и пути их применения |
| WO2016054094A1 (en) * | 2014-09-30 | 2016-04-07 | Research Institute At Nationwide Children's Hospital | Compositions and methods for treating hepatic fibrosis |
| CN112063714A (zh) * | 2014-10-28 | 2020-12-11 | 广州复能基因有限公司 | 一种与结直肠癌相关的miRNA及其应用 |
| CN104450707B (zh) * | 2014-12-25 | 2017-08-29 | 厦门大学 | 一种血清miRNA生物标志物的应用 |
| CN104694542A (zh) * | 2015-03-19 | 2015-06-10 | 中国人民解放军第四军医大学 | 一种促进组织工程骨血管化的 microRNA 及其应用 |
| CN105079808B (zh) * | 2015-05-22 | 2018-04-03 | 重庆医科大学 | miR590的用途及其相关药物 |
| WO2016205226A1 (en) * | 2015-06-15 | 2016-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosing and treating affective disorders |
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| CN105169393B (zh) * | 2015-08-31 | 2018-07-03 | 北京泱深生物信息技术有限公司 | miRNA-548a-3p抗急性髓系白血病中的应用 |
| US11180810B2 (en) | 2015-09-29 | 2021-11-23 | Research Institute At Nationwide Children's Hospital | Methods for detecting hepatic fibrosis and responsiveness to therapy |
| JP2017143810A (ja) * | 2016-02-19 | 2017-08-24 | 学校法人慶應義塾 | 抗酸菌症又は抗酸菌感染のバイオマーカー |
| CN106011303B (zh) * | 2016-08-08 | 2019-05-24 | 南京市妇幼保健院 | 一种与儿童肥胖相关的血清或血浆miRNA标志物及其应用 |
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| CN107236799B (zh) * | 2017-06-15 | 2020-06-09 | 昆明医科大学第六附属医院 | 一种肾纤维化miRNA标记物 |
| CN108186564B (zh) * | 2018-01-03 | 2020-06-02 | 上海市肿瘤研究所 | 一种肿瘤微环境响应型基因纳米胶束及其制备方法和应用 |
| CN108611414A (zh) * | 2018-04-26 | 2018-10-02 | 北京工业大学 | 新的靶向肿瘤微环境与肺癌干细胞相互作用的miRNA的检测及应用 |
| CN109486911A (zh) * | 2018-11-28 | 2019-03-19 | 上海纳米技术及应用国家工程研究中心有限公司 | 基于滚环扩增和DNA折纸术检测microRNAs的方法 |
| CN109825575A (zh) * | 2019-04-08 | 2019-05-31 | 首都医科大学附属北京胸科医院 | 辅助诊断结核病的miRNA标志物及其应用 |
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| JP7392224B2 (ja) * | 2020-02-19 | 2023-12-06 | 国立医薬品食品衛生研究所長 | びまん性肺胞傷害型薬剤性間質性肺炎のｍｉＲＮＡ診断バイオマーカー |
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| EP2096171A1 (en) * | 2008-02-27 | 2009-09-02 | Julius-Maximilians-Universität Würzburg | MicroRNA (miRNA) and down-stream targets for diagnostic and therapeutic purposes |
| WO2010039502A2 (en) * | 2008-09-23 | 2010-04-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Micrornas in idiopathic pulmonary fibrosis |
| WO2010054386A2 (en) * | 2008-11-10 | 2010-05-14 | Battelle Memorial Institute | Methods, compositions, and devices utilizing microrna to determine physiological conditions |
| WO2010068775A2 (en) | 2008-12-11 | 2010-06-17 | Amira Pharmaceuticals, Inc. | Alkyne antagonists of lysophosphatidic acid receptors |
| GB2466121B (en) | 2008-12-15 | 2010-12-08 | Amira Pharmaceuticals Inc | Antagonists of lysophosphatidic acid receptors |
| AP2011005824A0 (en) | 2009-01-26 | 2011-08-31 | Intermune Inc | Methods for treating acute myocardial infarctions and associated disorders. |
| US20120059020A1 (en) * | 2009-05-29 | 2012-03-08 | Shizuoka Coffein Co., Ltd | Prophylactic or therapeutic agent for pulmonary fibrosis |
| GB2470833B (en) | 2009-06-03 | 2011-06-01 | Amira Pharmaceuticals Inc | Polycyclic antagonists of lysophosphatidic acid receptors |
| WO2011017350A2 (en) | 2009-08-04 | 2011-02-10 | Amira Pharmaceuticals, Inc. | Compounds as lysophosphatidic acid receptor antagonists |
| GB2474120B (en) | 2009-10-01 | 2011-12-21 | Amira Pharmaceuticals Inc | Compounds as Lysophosphatidic acid receptor antagonists |
| GB2474748B (en) | 2009-10-01 | 2011-10-12 | Amira Pharmaceuticals Inc | Polycyclic compounds as lysophosphatidic acid receptor antagonists |
| US7816383B1 (en) * | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
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2012
- 2012-11-21 BR BR112014012288A patent/BR112014012288A2/pt not_active IP Right Cessation
- 2012-11-21 EA EA201491019A patent/EA201491019A1/ru unknown
- 2012-11-21 HK HK15101658.4A patent/HK1201299A1/xx unknown
- 2012-11-21 AU AU2012340698A patent/AU2012340698A1/en not_active Abandoned
- 2012-11-21 JP JP2014542588A patent/JP2015504307A/ja active Pending
- 2012-11-21 WO PCT/US2012/066221 patent/WO2013078283A1/en not_active Ceased
- 2012-11-21 EP EP12791944.7A patent/EP2783016A1/en not_active Withdrawn
- 2012-11-21 US US13/683,099 patent/US20130150426A1/en not_active Abandoned
- 2012-11-21 HK HK15101592.3A patent/HK1201298A1/xx unknown
- 2012-11-21 CN CN201280057373.1A patent/CN103987858A/zh active Pending
- 2012-11-21 CA CA2853136A patent/CA2853136A1/en not_active Abandoned
- 2012-11-21 MX MX2014006130A patent/MX2014006130A/es not_active Application Discontinuation
Also Published As
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|---|---|
| EA201491019A1 (ru) | 2014-08-29 |
| AU2012340698A1 (en) | 2014-04-24 |
| EP2783016A1 (en) | 2014-10-01 |
| CN103987858A (zh) | 2014-08-13 |
| US20130150426A1 (en) | 2013-06-13 |
| MX2014006130A (es) | 2015-04-13 |
| HK1201298A1 (en) | 2015-08-28 |
| BR112014012288A2 (pt) | 2017-05-23 |
| JP2015504307A (ja) | 2015-02-12 |
| WO2013078283A1 (en) | 2013-05-30 |
| HK1201299A1 (en) | 2015-08-28 |
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