JP2015198665A5 - - Google Patents

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Publication number
JP2015198665A5
JP2015198665A5 JP2015117465A JP2015117465A JP2015198665A5 JP 2015198665 A5 JP2015198665 A5 JP 2015198665A5 JP 2015117465 A JP2015117465 A JP 2015117465A JP 2015117465 A JP2015117465 A JP 2015117465A JP 2015198665 A5 JP2015198665 A5 JP 2015198665A5
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JP
Japan
Prior art keywords
enzyme
cell
seq
nicotinamide
nicotinamidase
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JP2015117465A
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English (en)
Japanese (ja)
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JP2015198665A (ja
JP6602561B2 (ja
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Publication of JP2015198665A publication Critical patent/JP2015198665A/ja
Publication of JP2015198665A5 publication Critical patent/JP2015198665A5/ja
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Publication of JP6602561B2 publication Critical patent/JP6602561B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2015117465A 2002-08-09 2015-06-10 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物 Expired - Fee Related JP6602561B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40225402P 2002-08-09 2002-08-09
US60/402,254 2002-08-09
US42861402P 2002-11-22 2002-11-22
US60/428,614 2002-11-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010162637A Division JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Publications (3)

Publication Number Publication Date
JP2015198665A JP2015198665A (ja) 2015-11-12
JP2015198665A5 true JP2015198665A5 (OSRAM) 2016-05-26
JP6602561B2 JP6602561B2 (ja) 2019-11-06

Family

ID=31720582

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004529297A Pending JP2005535342A (ja) 2002-08-09 2003-08-08 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2010162637A Pending JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2015117465A Expired - Fee Related JP6602561B2 (ja) 2002-08-09 2015-06-10 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2004529297A Pending JP2005535342A (ja) 2002-08-09 2003-08-08 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2010162637A Pending JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Country Status (5)

Country Link
EP (2) EP1551964A4 (OSRAM)
JP (3) JP2005535342A (OSRAM)
AU (2) AU2003264037B2 (OSRAM)
CA (2) CA2421269A1 (OSRAM)
WO (1) WO2004016726A2 (OSRAM)

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US20060025337A1 (en) 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
WO2005002672A2 (en) 2003-07-01 2005-01-13 President And Fellows Of Harvard College Sirt1 modulators for manipulating cells/organism lifespan/stress response
WO2006072809A2 (en) * 2003-10-31 2006-07-13 Robarts Research Institute Formulations that optimize intracellular concentration of nicotinamide adenine (nad+) and methods of use to protect cells and treat diseases and conditions
US8017634B2 (en) * 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
EP1708689A2 (en) 2003-12-29 2006-10-11 The President and Fellows of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
ES2557810T3 (es) * 2004-06-04 2016-01-28 Washington University Métodos y composiciones para tratar neuropatías
KR20120138840A (ko) * 2004-09-24 2012-12-26 바이엘 크롭사이언스 엔.브이. 스트레스 내성 식물
WO2006081329A2 (en) * 2005-01-25 2006-08-03 The Johns Hopkins University Strategies for designing drugs that target the sir2 family of enzymes
EP2805719A1 (en) 2005-03-30 2014-11-26 Glaxosmithkline LLC Nicotinamide riboside and analogues thereof
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
MX2007016199A (es) * 2005-06-15 2008-03-11 Bayer Bioscience Nv Metodos para aumentar la resistencia de plantas a condiciones hipoxicas.
US8158856B2 (en) * 2006-03-21 2012-04-17 Bayer Cropscience Nv Stress resistant plants
EP2103212B1 (en) 2006-12-11 2014-08-06 Japan Science and Technology Agency Plant growth regulator and use thereof
AU2008321944B2 (en) * 2007-11-13 2011-01-27 Japan Science And Technology Agency Composition for production of plant body having improved sugar content, and use thereof
JP5570731B2 (ja) * 2008-02-28 2014-08-13 旭化成ファーマ株式会社 ピロリン酸の測定方法
JP5684578B2 (ja) 2008-03-03 2015-03-11 エヌエーディー ライフ プロプライエタリー リミテッド リスベラトロールの医薬製剤、および細胞障害を治療するためのその使用方法
JP2011115098A (ja) * 2009-12-04 2011-06-16 Nippon Menaade Keshohin Kk 加齢による皮膚明度の低下を予測する皮膚評価方法
CN103987249B (zh) 2011-12-12 2015-10-21 冈山县 用于提高植物的氨基酸含量的化合物及其应用
WO2014059034A2 (en) 2012-10-09 2014-04-17 President And Fellows Of Harvard College Nad biosynthesis and precursors for the treatment and prevention of cancer and proliferation
WO2015069860A1 (en) * 2013-11-06 2015-05-14 President And Fellows Of Harvard College Biological production of nad precursors and analogs
US10316054B2 (en) 2014-06-02 2019-06-11 Glaxosmithkline Intellectual Property (No. 2) Limited Preparation and use of crystalline beta-D-nicotinamide riboside
EP3152220A1 (en) 2014-06-06 2017-04-12 Glaxosmithkline Intellectual Property (No. 2) Limited Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof
JP6623015B2 (ja) * 2014-09-29 2019-12-18 国立研究開発法人理化学研究所 植物の耐塩性向上剤
WO2020097116A1 (en) * 2018-11-05 2020-05-14 Rejuvenation Therapeutics Compositions and methods for culturing yeast cells
CN114555619A (zh) * 2019-08-14 2022-05-27 麦德龙国际生物科技有限责任公司 用于烟酰胺腺嘌呤二核苷酸的差分调节的化合物和组合物
CN111394268B (zh) 2019-12-20 2021-06-18 合肥康诺生物制药有限公司 基因工程菌及其构建方法、应用，生产nad+的方法
CN112451673A (zh) * 2020-12-10 2021-03-09 汤臣倍健股份有限公司 线粒体功能干预材料在制备改善线粒体功能的保健品或药品中的应用及其筛选方法

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KR20120138840A (ko) * 2004-09-24 2012-12-26 바이엘 크롭사이언스 엔.브이. 스트레스 내성 식물
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