CA2421269A1 - Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms - Google Patents
Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms Download PDFInfo
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- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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| WO (1) | WO2004016726A2 (OSRAM) |
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| US20060025337A1 (en) | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| WO2005002672A2 (en) | 2003-07-01 | 2005-01-13 | President And Fellows Of Harvard College | Sirt1 modulators for manipulating cells/organism lifespan/stress response |
| US8017634B2 (en) * | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| EP1708689A2 (en) | 2003-12-29 | 2006-10-11 | The President and Fellows of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| ES2557810T3 (es) * | 2004-06-04 | 2016-01-28 | Washington University | Métodos y composiciones para tratar neuropatías |
| KR20120138840A (ko) * | 2004-09-24 | 2012-12-26 | 바이엘 크롭사이언스 엔.브이. | 스트레스 내성 식물 |
| WO2006081329A2 (en) * | 2005-01-25 | 2006-08-03 | The Johns Hopkins University | Strategies for designing drugs that target the sir2 family of enzymes |
| EP2805719A1 (en) | 2005-03-30 | 2014-11-26 | Glaxosmithkline LLC | Nicotinamide riboside and analogues thereof |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| MX2007016199A (es) * | 2005-06-15 | 2008-03-11 | Bayer Bioscience Nv | Metodos para aumentar la resistencia de plantas a condiciones hipoxicas. |
| US8158856B2 (en) * | 2006-03-21 | 2012-04-17 | Bayer Cropscience Nv | Stress resistant plants |
| EP2103212B1 (en) | 2006-12-11 | 2014-08-06 | Japan Science and Technology Agency | Plant growth regulator and use thereof |
| AU2008321944B2 (en) * | 2007-11-13 | 2011-01-27 | Japan Science And Technology Agency | Composition for production of plant body having improved sugar content, and use thereof |
| JP5570731B2 (ja) * | 2008-02-28 | 2014-08-13 | 旭化成ファーマ株式会社 | ピロリン酸の測定方法 |
| JP5684578B2 (ja) | 2008-03-03 | 2015-03-11 | エヌエーディー ライフ プロプライエタリー リミテッド | リスベラトロールの医薬製剤、および細胞障害を治療するためのその使用方法 |
| JP2011115098A (ja) * | 2009-12-04 | 2011-06-16 | Nippon Menaade Keshohin Kk | 加齢による皮膚明度の低下を予測する皮膚評価方法 |
| CN103987249B (zh) | 2011-12-12 | 2015-10-21 | 冈山县 | 用于提高植物的氨基酸含量的化合物及其应用 |
| WO2014059034A2 (en) | 2012-10-09 | 2014-04-17 | President And Fellows Of Harvard College | Nad biosynthesis and precursors for the treatment and prevention of cancer and proliferation |
| WO2015069860A1 (en) * | 2013-11-06 | 2015-05-14 | President And Fellows Of Harvard College | Biological production of nad precursors and analogs |
| US10316054B2 (en) | 2014-06-02 | 2019-06-11 | Glaxosmithkline Intellectual Property (No. 2) Limited | Preparation and use of crystalline beta-D-nicotinamide riboside |
| EP3152220A1 (en) | 2014-06-06 | 2017-04-12 | Glaxosmithkline Intellectual Property (No. 2) Limited | Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof |
| JP6623015B2 (ja) * | 2014-09-29 | 2019-12-18 | 国立研究開発法人理化学研究所 | 植物の耐塩性向上剤 |
| WO2020097116A1 (en) * | 2018-11-05 | 2020-05-14 | Rejuvenation Therapeutics | Compositions and methods for culturing yeast cells |
| CN114555619A (zh) * | 2019-08-14 | 2022-05-27 | 麦德龙国际生物科技有限责任公司 | 用于烟酰胺腺嘌呤二核苷酸的差分调节的化合物和组合物 |
| CN111394268B (zh) | 2019-12-20 | 2021-06-18 | 合肥康诺生物制药有限公司 | 基因工程菌及其构建方法、应用，生产nad+的方法 |
| CN112451673A (zh) * | 2020-12-10 | 2021-03-09 | 汤臣倍健股份有限公司 | 线粒体功能干预材料在制备改善线粒体功能的保健品或药品中的应用及其筛选方法 |
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2003
- 2003-03-07 CA CA002421269A patent/CA2421269A1/en not_active Abandoned
- 2003-08-08 AU AU2003264037A patent/AU2003264037B2/en not_active Ceased
- 2003-08-08 EP EP03788377A patent/EP1551964A4/en not_active Withdrawn
- 2003-08-08 CA CA002495185A patent/CA2495185A1/en not_active Abandoned
- 2003-08-08 EP EP11179088A patent/EP2431480A3/en not_active Withdrawn
- 2003-08-08 WO PCT/US2003/025016 patent/WO2004016726A2/en not_active Ceased
- 2003-08-08 JP JP2004529297A patent/JP2005535342A/ja active Pending
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2010
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2015
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006072809A3 (en) * | 2003-10-31 | 2006-11-02 | Robarts Res Inst | Formulations that optimize intracellular concentration of nicotinamide adenine (nad+) and methods of use to protect cells and treat diseases and conditions |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003264037B2 (en) | 2010-06-17 |
| WO2004016726A9 (en) | 2005-08-04 |
| WO2004016726A3 (en) | 2005-05-19 |
| AU2010219395A1 (en) | 2010-09-30 |
| CA2495185A1 (en) | 2004-02-26 |
| JP2011015682A (ja) | 2011-01-27 |
| EP2431480A3 (en) | 2012-09-05 |
| AU2003264037A1 (en) | 2004-03-03 |
| JP2015198665A (ja) | 2015-11-12 |
| EP1551964A4 (en) | 2010-07-28 |
| AU2010219395B2 (en) | 2011-07-14 |
| EP2431480A2 (en) | 2012-03-21 |
| EP1551964A2 (en) | 2005-07-13 |
| JP6602561B2 (ja) | 2019-11-06 |
| WO2004016726A2 (en) | 2004-02-26 |
| JP2005535342A (ja) | 2005-11-24 |
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