JP2015120756A5 - - Google Patents
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- Publication number
- JP2015120756A5 JP2015120756A5 JP2015068416A JP2015068416A JP2015120756A5 JP 2015120756 A5 JP2015120756 A5 JP 2015120756A5 JP 2015068416 A JP2015068416 A JP 2015068416A JP 2015068416 A JP2015068416 A JP 2015068416A JP 2015120756 A5 JP2015120756 A5 JP 2015120756A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- layer
- range
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 238000013270 controlled release Methods 0.000 claims 4
- 229920001577 copolymer Polymers 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 239000006057 Non-nutritive feed additive Substances 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 239000002518 antifoaming agent Substances 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- MSYKRHVOOPPJKU-BDAKNGLRSA-N brivaracetam Chemical group CCC[C@H]1CN([C@@H](CC)C(N)=O)C(=O)C1 MSYKRHVOOPPJKU-BDAKNGLRSA-N 0.000 claims 1
- 229960002161 brivaracetam Drugs 0.000 claims 1
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 235000019325 ethyl cellulose Nutrition 0.000 claims 1
- 229920001249 ethyl cellulose Polymers 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000011236 particulate material Substances 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 claims 1
- ANWPENAPCIFDSZ-BQBZGAKWSA-N seletracetam Chemical compound CC[C@@H](C(N)=O)N1C[C@@H](C=C(F)F)CC1=O ANWPENAPCIFDSZ-BQBZGAKWSA-N 0.000 claims 1
- 229950000852 seletracetam Drugs 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000000454 talc Substances 0.000 claims 1
- 229910052623 talc Inorganic materials 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08105817 | 2008-11-18 | ||
| EP08105817.4 | 2008-11-18 | ||
| EP09100312.9 | 2009-06-02 | ||
| EP09100312 | 2009-06-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543763A Division JP5954890B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015120756A JP2015120756A (ja) | 2015-07-02 |
| JP2015120756A5 true JP2015120756A5 (enExample) | 2016-02-12 |
Family
ID=41381618
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543763A Active JP5954890B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
| JP2015068416A Pending JP2015120756A (ja) | 2008-11-18 | 2015-03-30 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543763A Active JP5954890B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10172805B2 (enExample) |
| EP (1) | EP2358360B1 (enExample) |
| JP (2) | JP5954890B2 (enExample) |
| KR (1) | KR101689688B1 (enExample) |
| CN (2) | CN102215829B (enExample) |
| AU (1) | AU2009317280B2 (enExample) |
| BR (1) | BRPI0921313A2 (enExample) |
| CA (1) | CA2741041C (enExample) |
| DK (1) | DK2358360T3 (enExample) |
| EA (1) | EA019572B1 (enExample) |
| ES (1) | ES2602604T3 (enExample) |
| HU (1) | HUE032275T2 (enExample) |
| IL (1) | IL212447A (enExample) |
| MX (1) | MX339852B (enExample) |
| PL (1) | PL2358360T3 (enExample) |
| PT (1) | PT2358360T (enExample) |
| WO (1) | WO2010057870A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2346500B1 (en) | 2008-10-16 | 2017-05-17 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| KR101689688B1 (ko) * | 2008-11-18 | 2016-12-26 | 유씨비 파마, 에스.에이. | ２옥소１피롤리딘 유도체를 포함하는 지연 방출형 제형 |
| WO2011107855A2 (en) * | 2010-03-04 | 2011-09-09 | Torrent Pharmaceuticals Limited | Sustained release oral liquid suspension dosage form |
| EP2563339A1 (en) * | 2010-04-29 | 2013-03-06 | Lupin Limited | Controlled release pharmaceutical compositions of brivaracetam |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| EA034167B8 (ru) | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
| EP3127539A1 (en) * | 2015-08-03 | 2017-02-08 | Latvian Institute Of Organic Synthesis | Use of 2-(5s-methyl-2-oxo-4r-phenyl-pyrrolidin-1-yl)-acetamide in the treatment of seizures |
| EP3397253A1 (en) | 2015-12-30 | 2018-11-07 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of seizure-related disorders |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN111407738A (zh) * | 2020-04-03 | 2020-07-14 | 江苏艾立康药业股份有限公司 | 一种布立西坦控释制剂及其制备方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6327424A (ja) | 1986-07-17 | 1988-02-05 | Shionogi & Co Ltd | 徐放性製剤およびその製造法 |
| US5026560A (en) | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
| US5622716A (en) | 1987-02-20 | 1997-04-22 | Farmarc Nederland B.V. | Process for preparing a retard product containing diltiazem for a single daily administration |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| EP0452862B1 (en) * | 1990-04-18 | 1995-07-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Spherical seed cores, spherical granules and process for production thereof |
| JP2558396B2 (ja) * | 1990-06-28 | 1996-11-27 | 田辺製薬株式会社 | 放出制御型製剤 |
| JPH10182438A (ja) * | 1991-03-07 | 1998-07-07 | Takeda Chem Ind Ltd | 有核散剤 |
| DE19630035A1 (de) | 1996-07-25 | 1998-01-29 | Asta Medica Ag | Tramadol Multiple Unit Formulierungen |
| US6919373B1 (en) * | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
| US5997905A (en) | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
| GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| US8168170B2 (en) * | 2002-10-03 | 2012-05-01 | The Procter And Gamble Company | Compositions having an inner core and at least three surrounding layers |
| ZA200505180B (en) | 2002-11-28 | 2006-10-25 | Themis Lab Private Ltd | Process for manufacturing sustained release microbeads containing venlafaxine HCI |
| DE10353186A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz |
| SI21637A (sl) * | 2003-12-23 | 2005-06-30 | LEK farmacevtska dru�ba d.d. | Farmacevtska oblika z nadzorovanim sproščanjem |
| US20070298098A1 (en) * | 2005-02-16 | 2007-12-27 | Elan Pharma International Limited | Controlled Release Compositions Comprising Levetiracetam |
| WO2006088864A1 (en) | 2005-02-16 | 2006-08-24 | Elan Pharma International Limited | Controlled release compositions comprising levetiracetam |
| CA2600282A1 (en) * | 2005-03-29 | 2006-10-05 | Roehm Gmbh | Multiparticulate pharmaceutical form comprising pellets with a substance having a modular effect in relation to active ingredient release |
| WO2006125074A1 (en) * | 2005-05-17 | 2006-11-23 | Brown University Research Foundation | Drug delivery formulations for targeted delivery |
| US20070264346A1 (en) * | 2006-02-16 | 2007-11-15 | Flamel Technologies | Multimicroparticulate pharmaceutical forms for oral administration |
| FR2897267A1 (fr) | 2006-02-16 | 2007-08-17 | Flamel Technologies Sa | Formes pharmaceutiques multimicroparticulaires pour administration per os |
| EP2041084B1 (en) | 2006-06-08 | 2013-11-06 | UCB Pharma, S.A. | Co-crystals of pyrrolidinones |
| DE102006035549A1 (de) * | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
| NZ575171A (en) * | 2006-08-31 | 2012-04-27 | Aptalis Pharmatech Inc | Drug delivery systems comprising solid solutions of weakly basic drugs |
| CN101801356B (zh) * | 2007-09-21 | 2016-10-19 | 赢创罗姆有限公司 | 耐受乙醇影响的非阿片类的pH依赖性受控释放的药物组合物 |
| WO2009102964A2 (en) * | 2008-02-14 | 2009-08-20 | Nordson Corporation | Apparatus for testing containers, tray for holding cylinders and suction-basedchuck for robotic arm |
| KR101788804B1 (ko) * | 2008-11-18 | 2017-10-20 | 유씨비 파마, 에스.에이. | ２―옥소―１―피롤리딘 유도체를 포함하는 연장 방출 제형 |
| KR101689688B1 (ko) * | 2008-11-18 | 2016-12-26 | 유씨비 파마, 에스.에이. | ２옥소１피롤리딘 유도체를 포함하는 지연 방출형 제형 |
-
2009
- 2009-11-17 KR KR1020117013972A patent/KR101689688B1/ko active Active
- 2009-11-17 JP JP2011543763A patent/JP5954890B2/ja active Active
- 2009-11-17 CN CN200980145828.3A patent/CN102215829B/zh active Active
- 2009-11-17 WO PCT/EP2009/065271 patent/WO2010057870A1/en not_active Ceased
- 2009-11-17 MX MX2011004816A patent/MX339852B/es active IP Right Grant
- 2009-11-17 EP EP09751938.3A patent/EP2358360B1/en active Active
- 2009-11-17 EA EA201100752A patent/EA019572B1/ru unknown
- 2009-11-17 PL PL09751938T patent/PL2358360T3/pl unknown
- 2009-11-17 ES ES09751938.3T patent/ES2602604T3/es active Active
- 2009-11-17 US US13/129,114 patent/US10172805B2/en active Active
- 2009-11-17 AU AU2009317280A patent/AU2009317280B2/en active Active
- 2009-11-17 BR BRPI0921313A patent/BRPI0921313A2/pt not_active IP Right Cessation
- 2009-11-17 PT PT97519383T patent/PT2358360T/pt unknown
- 2009-11-17 CA CA2741041A patent/CA2741041C/en active Active
- 2009-11-17 HU HUE09751938A patent/HUE032275T2/en unknown
- 2009-11-17 DK DK09751938.3T patent/DK2358360T3/en active
- 2009-11-17 CN CN201410407641.9A patent/CN104208714A/zh active Pending
-
2011
- 2011-04-26 IL IL212447A patent/IL212447A/en active IP Right Grant
-
2015
- 2015-03-30 JP JP2015068416A patent/JP2015120756A/ja active Pending
-
2019
- 2019-01-07 US US16/241,184 patent/US20190142759A1/en not_active Abandoned
- 2019-07-12 US US16/509,919 patent/US20200085754A1/en not_active Abandoned
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