JP2013502993A5 - - Google Patents
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- Publication number
- JP2013502993A5 JP2013502993A5 JP2012526927A JP2012526927A JP2013502993A5 JP 2013502993 A5 JP2013502993 A5 JP 2013502993A5 JP 2012526927 A JP2012526927 A JP 2012526927A JP 2012526927 A JP2012526927 A JP 2012526927A JP 2013502993 A5 JP2013502993 A5 JP 2013502993A5
- Authority
- JP
- Japan
- Prior art keywords
- particles
- polymer
- combination
- preparation according
- soluble polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims 25
- 239000000203 mixture Substances 0.000 claims 10
- 229920002988 biodegradable polymer Polymers 0.000 claims 9
- 239000004621 biodegradable polymer Substances 0.000 claims 9
- 229920003169 water-soluble polymer Polymers 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 8
- 238000002360 preparation method Methods 0.000 claims 8
- 239000007788 liquid Substances 0.000 claims 6
- 238000009472 formulation Methods 0.000 claims 5
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 5
- 230000004888 barrier function Effects 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 3
- 229920001661 Chitosan Polymers 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 229960001126 alginic acid Drugs 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 239000000783 alginic acid Substances 0.000 claims 2
- 150000004781 alginic acids Chemical class 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 238000009835 boiling Methods 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 229940030225 antihemorrhagics Drugs 0.000 claims 1
- 229960005475 antiinfective agent Drugs 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000002874 hemostatic agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23766909P | 2009-08-27 | 2009-08-27 | |
| US61/237,669 | 2009-08-27 | ||
| US12/705,436 | 2010-02-12 | ||
| US12/705,436 US9649331B2 (en) | 2009-08-27 | 2010-02-12 | Sprayable polymers as adhesion barriers |
| PCT/US2010/046529 WO2011031457A2 (en) | 2009-08-27 | 2010-08-24 | Sprayable polymers as adhesion barriers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502993A JP2013502993A (ja) | 2013-01-31 |
| JP2013502993A5 true JP2013502993A5 (enExample) | 2013-10-03 |
| JP5792724B2 JP5792724B2 (ja) | 2015-10-14 |
Family
ID=43625293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012526927A Active JP5792724B2 (ja) | 2009-08-27 | 2010-08-24 | 癒着防止バリアとしての噴霧可能なポリマー |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US9649331B2 (enExample) |
| EP (1) | EP2470223B1 (enExample) |
| JP (1) | JP5792724B2 (enExample) |
| CA (1) | CA2772343A1 (enExample) |
| WO (1) | WO2011031457A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9649331B2 (en) * | 2009-08-27 | 2017-05-16 | Ara Medical Llc | Sprayable polymers as adhesion barriers |
| DE102011114986A1 (de) | 2011-09-28 | 2013-03-28 | Ethris Gmbh | Sprühsystem |
| CN102433684B (zh) * | 2011-11-04 | 2015-06-10 | 无锡中科光远生物材料有限公司 | 一种超细复合纤维膜、其制备方法及其用途 |
| AU2012341502B2 (en) * | 2011-11-25 | 2016-05-26 | Otsuka Pharmaceutical Factory, Inc. | Pharmaceutical composition useful for adhesion prevention or hemostasis |
| DE102013211316A1 (de) | 2013-06-17 | 2014-12-18 | Aesculap Ag | Hämostyptikum |
| WO2015089317A1 (en) * | 2013-12-11 | 2015-06-18 | Case Western Reserve University | Spray on hemostatic system |
| US9962462B2 (en) * | 2015-06-11 | 2018-05-08 | Case Western Reserve University | Dry spray on hemostatic system |
| AU2018332189B2 (en) * | 2017-09-12 | 2021-08-19 | Shilpa Medicare Limited | Tranexamic acid spray for knee arthroplasty |
| US10624729B2 (en) | 2017-10-12 | 2020-04-21 | C.R. Bard, Inc. | Repair prosthetic curl mitigation |
| US11013501B2 (en) | 2017-12-08 | 2021-05-25 | Davol, Inc. | Method of protecting the peritoneum against tearing and other injury before an active surgical intervention at or near the peritoneum |
| US12263185B2 (en) * | 2018-02-05 | 2025-04-01 | Bc3 Technologies, Inc. | Hemostatic material and spray |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8416234D0 (en) * | 1984-06-26 | 1984-08-01 | Ici Plc | Biodegradable amphipathic copolymers |
| US4895724A (en) * | 1985-06-07 | 1990-01-23 | Pfizer Inc. | Chitosan compositions for controlled and prolonged release of macromolecules |
| US5725491A (en) * | 1988-10-03 | 1998-03-10 | Atrix Laboratories, Inc. | Method of forming a biodegradable film dressing on tissue |
| DE3916020C2 (de) | 1989-05-17 | 1994-06-01 | Burkhard Dr Wichert | Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen |
| US5626863A (en) * | 1992-02-28 | 1997-05-06 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| BR9306038A (pt) * | 1992-02-28 | 1998-01-13 | Univ Texas | Hidrogéis biodegradáveis fotopolimerizáveis como materiais de contato de tecidos e condutores de liberação controlada |
| US6696499B1 (en) * | 1996-07-11 | 2004-02-24 | Life Medical Sciences, Inc. | Methods and compositions for reducing or eliminating post-surgical adhesion formation |
| US5711958A (en) * | 1996-07-11 | 1998-01-27 | Life Medical Sciences, Inc. | Methods for reducing or eliminating post-surgical adhesion formation |
| US5836970A (en) * | 1996-08-02 | 1998-11-17 | The Kendall Company | Hemostatic wound dressing |
| US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
| US5906997A (en) | 1997-06-17 | 1999-05-25 | Fzio Med, Inc. | Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions |
| US6869938B1 (en) | 1997-06-17 | 2005-03-22 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use in reducing adhesions |
| GB9800957D0 (en) | 1998-01-17 | 1998-03-11 | Process Intelligence Limited | Test probe interface unit and method for manufacturing the same |
| AU5560899A (en) * | 1998-08-14 | 2000-03-06 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| US7347850B2 (en) * | 1998-08-14 | 2008-03-25 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
| US6153212A (en) | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
| ATE318846T1 (de) | 1999-11-12 | 2006-03-15 | Macromed Inc | An- und abschwellende polymermischungen |
| US6566345B2 (en) | 2000-04-28 | 2003-05-20 | Fziomed, Inc. | Polyacid/polyalkylene oxide foams and gels and methods for their delivery |
| EP1292316B1 (en) | 2000-04-28 | 2009-03-18 | Fziomed Inc. | Hemostatic compositions of polyacids and polyalkylene oxides and methods for their use |
| US20040018238A1 (en) | 2001-02-26 | 2004-01-29 | Shukla Atul J | Biodegradable vehicles and delivery systems of biolgically active substances |
| KR100523953B1 (ko) | 2002-08-27 | 2005-10-25 | 주식회사 엘지생명과학 | 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법 |
| US20050048115A1 (en) | 2003-08-27 | 2005-03-03 | Murty Mangena | Buprenorphine microspheres |
| TW200524959A (en) | 2003-09-08 | 2005-08-01 | Chugai Pharmaceutical Co Ltd | Hyaluronic acid modification product and drug carrier therefrom |
| DE602005026015D1 (de) | 2004-08-17 | 2011-03-03 | Tyco Healthcare | Antiadhäsionssperrschicht |
| JP5226513B2 (ja) * | 2005-08-26 | 2013-07-03 | メルク セローノ ソシエテ アノニム | ピラジン誘導体及びその使用 |
| KR100785378B1 (ko) | 2005-09-05 | 2007-12-14 | 주식회사 바이오레인 | 다층구조의 유착방지제 |
| US20070248642A1 (en) * | 2006-04-19 | 2007-10-25 | Michael Dornish | Foam and use thereof |
| US20070299155A1 (en) | 2006-06-09 | 2007-12-27 | Medivas, Llc | Biodegradable polymer adhesion barriers |
| US8153695B2 (en) * | 2007-06-04 | 2012-04-10 | Boston Scientific Scimed, Inc. | Methods for inhibiting post-surgical adhesions |
| EP3574909A1 (en) * | 2008-01-30 | 2019-12-04 | Imbed Biosciences, Inc. | Methods and compositions for wound healing |
| US9649331B2 (en) | 2009-08-27 | 2017-05-16 | Ara Medical Llc | Sprayable polymers as adhesion barriers |
-
2010
- 2010-02-12 US US12/705,436 patent/US9649331B2/en not_active Expired - Fee Related
- 2010-08-24 JP JP2012526927A patent/JP5792724B2/ja active Active
- 2010-08-24 WO PCT/US2010/046529 patent/WO2011031457A2/en not_active Ceased
- 2010-08-24 EP EP10815827.0A patent/EP2470223B1/en active Active
- 2010-08-24 CA CA2772343A patent/CA2772343A1/en not_active Abandoned
-
2017
- 2017-04-24 US US15/495,710 patent/US10543168B2/en active Active
-
2018
- 2018-08-01 US US16/052,487 patent/US20190070102A1/en not_active Abandoned
-
2021
- 2021-08-04 US US17/394,079 patent/US20220054403A1/en not_active Abandoned
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