JP2015143256A5 - - Google Patents
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- Publication number
- JP2015143256A5 JP2015143256A5 JP2015071166A JP2015071166A JP2015143256A5 JP 2015143256 A5 JP2015143256 A5 JP 2015143256A5 JP 2015071166 A JP2015071166 A JP 2015071166A JP 2015071166 A JP2015071166 A JP 2015071166A JP 2015143256 A5 JP2015143256 A5 JP 2015143256A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- range
- layer
- ethyl acrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 238000013270 controlled release Methods 0.000 claims 4
- 229920001577 copolymer Polymers 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 239000008187 granular material Substances 0.000 claims 3
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 2
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 239000006057 Non-nutritive feed additive Substances 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 239000002518 antifoaming agent Substances 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- MSYKRHVOOPPJKU-BDAKNGLRSA-N brivaracetam Chemical compound CCC[C@H]1CN([C@@H](CC)C(N)=O)C(=O)C1 MSYKRHVOOPPJKU-BDAKNGLRSA-N 0.000 claims 1
- 229960002161 brivaracetam Drugs 0.000 claims 1
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 229920001249 ethyl cellulose Polymers 0.000 claims 1
- 235000019325 ethyl cellulose Nutrition 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000011236 particulate material Substances 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 claims 1
- ANWPENAPCIFDSZ-BQBZGAKWSA-N seletracetam Chemical compound CC[C@@H](C(N)=O)N1C[C@@H](C=C(F)F)CC1=O ANWPENAPCIFDSZ-BQBZGAKWSA-N 0.000 claims 1
- 229950000852 seletracetam Drugs 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08105817.4 | 2008-11-18 | ||
| EP08105817 | 2008-11-18 | ||
| EP09100311.1 | 2009-06-02 | ||
| EP09100311 | 2009-06-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543762A Division JP5954889B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015143256A JP2015143256A (ja) | 2015-08-06 |
| JP2015143256A5 true JP2015143256A5 (enExample) | 2016-02-12 |
Family
ID=41395028
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543762A Active JP5954889B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
| JP2015071166A Pending JP2015143256A (ja) | 2008-11-18 | 2015-03-31 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543762A Active JP5954889B2 (ja) | 2008-11-18 | 2009-11-17 | ２−オキソ−１−ピロリジン誘導体を含む持続放出製剤 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8460712B2 (enExample) |
| EP (1) | EP2358361B1 (enExample) |
| JP (2) | JP5954889B2 (enExample) |
| KR (2) | KR20110089184A (enExample) |
| CN (2) | CN104083341A (enExample) |
| AU (1) | AU2009317279B2 (enExample) |
| BR (1) | BRPI0921301A2 (enExample) |
| CA (1) | CA2741038C (enExample) |
| DK (1) | DK2358361T3 (enExample) |
| EA (1) | EA019583B1 (enExample) |
| ES (1) | ES2602606T3 (enExample) |
| HK (1) | HK1198288A1 (enExample) |
| HU (1) | HUE030963T2 (enExample) |
| IL (1) | IL212271A (enExample) |
| MX (1) | MX356281B (enExample) |
| PL (1) | PL2358361T3 (enExample) |
| PT (1) | PT2358361T (enExample) |
| WO (1) | WO2010057869A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2741041C (en) * | 2008-11-18 | 2015-01-13 | Ucb Pharma S.A. | Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivative |
| AU2016381366A1 (en) | 2015-12-30 | 2018-06-28 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of seizure-related disorders |
| WO2017195144A1 (en) * | 2016-05-12 | 2017-11-16 | Jubilant Generics Limited | Pharmaceutical compositions comprising brivaracetam |
| WO2022238401A1 (en) * | 2021-05-11 | 2022-11-17 | Advicenne | Prolonged-release pharmaceutical composition for oral administration of sultiame |
| CN115721624A (zh) * | 2021-08-25 | 2023-03-03 | 北京海美源医药科技有限公司 | 一种布立西坦药物组合物及其制备方法和其应用 |
| WO2025128057A1 (en) * | 2023-12-13 | 2025-06-19 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | A sachet formulation comprising brivaracetam |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| JP5739080B2 (ja) | 2005-01-27 | 2015-06-24 | アレムビック・リミテッドＡｌｅｍｂｉｃ Ｌｉｍｉｔｅｄ | レベチラセタムの徐放性製剤 |
| US20070298098A1 (en) * | 2005-02-16 | 2007-12-27 | Elan Pharma International Limited | Controlled Release Compositions Comprising Levetiracetam |
| WO2006088864A1 (en) * | 2005-02-16 | 2006-08-24 | Elan Pharma International Limited | Controlled release compositions comprising levetiracetam |
| EP1909770B1 (en) | 2005-02-22 | 2013-03-20 | Sun Pharmaceutical Industries Limited | Oral controlled release composition containing levetiracetam |
| EP1863453A2 (en) * | 2005-03-29 | 2007-12-12 | Evonik Röhm GmbH | Multiparticulate pharmaceutical form comprising pellets with a substance having a modular effect in relation to active ingredient release |
| FR2897267A1 (fr) * | 2006-02-16 | 2007-08-17 | Flamel Technologies Sa | Formes pharmaceutiques multimicroparticulaires pour administration per os |
| EP2041084B1 (en) * | 2006-06-08 | 2013-11-06 | UCB Pharma, S.A. | Co-crystals of pyrrolidinones |
| CA2661683C (en) * | 2006-08-31 | 2015-11-24 | Eurand, Inc | Drug delivery systems comprising solid solutions of weakly basic drugs |
| WO2008062446A2 (en) * | 2006-09-14 | 2008-05-29 | Alembic Limited | An extended release composition of levetiracetam, which exhibits no adverse food effect |
| PL2187875T3 (pl) * | 2007-09-21 | 2013-01-31 | Evonik Roehm Gmbh | Kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu dla nieopioidów z odpornością przed wpływem etanolu |
| ES2474945T3 (es) * | 2008-03-03 | 2014-07-10 | Ucb Pharma, S.A. | Soluciones farmacéuticas, procedimiento de preparación y usos terapéuticos |
-
2009
- 2009-11-17 MX MX2011004572A patent/MX356281B/es active IP Right Grant
- 2009-11-17 CN CN201410370727.9A patent/CN104083341A/zh active Pending
- 2009-11-17 CN CN2009801455887A patent/CN102215828A/zh active Pending
- 2009-11-17 ES ES09752825.1T patent/ES2602606T3/es active Active
- 2009-11-17 EA EA201100753A patent/EA019583B1/ru unknown
- 2009-11-17 EP EP09752825.1A patent/EP2358361B1/en active Active
- 2009-11-17 PT PT97528251T patent/PT2358361T/pt unknown
- 2009-11-17 JP JP2011543762A patent/JP5954889B2/ja active Active
- 2009-11-17 KR KR1020117014019A patent/KR20110089184A/ko not_active Ceased
- 2009-11-17 US US13/128,950 patent/US8460712B2/en active Active
- 2009-11-17 AU AU2009317279A patent/AU2009317279B2/en active Active
- 2009-11-17 KR KR1020177000418A patent/KR101788804B1/ko active Active
- 2009-11-17 DK DK09752825.1T patent/DK2358361T3/en active
- 2009-11-17 PL PL09752825T patent/PL2358361T3/pl unknown
- 2009-11-17 HU HUE09752825A patent/HUE030963T2/en unknown
- 2009-11-17 CA CA2741038A patent/CA2741038C/en active Active
- 2009-11-17 BR BRPI0921301A patent/BRPI0921301A2/pt not_active IP Right Cessation
- 2009-11-17 WO PCT/EP2009/065270 patent/WO2010057869A1/en not_active Ceased
-
2011
- 2011-04-12 IL IL212271A patent/IL212271A/en active IP Right Grant
-
2014
- 2014-11-21 HK HK14111805.6A patent/HK1198288A1/xx unknown
-
2015
- 2015-03-31 JP JP2015071166A patent/JP2015143256A/ja active Pending
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