JP2015110588A5 - - Google Patents
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- Publication number
- JP2015110588A5 JP2015110588A5 JP2014263345A JP2014263345A JP2015110588A5 JP 2015110588 A5 JP2015110588 A5 JP 2015110588A5 JP 2014263345 A JP2014263345 A JP 2014263345A JP 2014263345 A JP2014263345 A JP 2014263345A JP 2015110588 A5 JP2015110588 A5 JP 2015110588A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- use according
- klh
- formulated
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 1
- 206010002022 amyloidosis Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA952/2008 | 2008-06-12 | ||
| AT0095208A AT506820B1 (de) | 2008-06-12 | 2008-06-12 | Vakzine gegen alzheimer-krankheit |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512780A Division JP2011522840A (ja) | 2008-06-12 | 2009-06-12 | アミロイドーシス治療のための化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015110588A JP2015110588A (ja) | 2015-06-18 |
| JP2015110588A5 true JP2015110588A5 (enExample) | 2015-11-05 |
| JP5989074B2 JP5989074B2 (ja) | 2016-09-07 |
Family
ID=41401983
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512780A Pending JP2011522840A (ja) | 2008-06-12 | 2009-06-12 | アミロイドーシス治療のための化合物 |
| JP2014073229A Expired - Fee Related JP5984867B2 (ja) | 2008-06-12 | 2014-03-31 | アミロイドーシス治療のための化合物 |
| JP2014263345A Expired - Fee Related JP5989074B2 (ja) | 2008-06-12 | 2014-12-25 | アミロイドーシス治療のための化合物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512780A Pending JP2011522840A (ja) | 2008-06-12 | 2009-06-12 | アミロイドーシス治療のための化合物 |
| JP2014073229A Expired - Fee Related JP5984867B2 (ja) | 2008-06-12 | 2014-03-31 | アミロイドーシス治療のための化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8409581B2 (enExample) |
| EP (1) | EP2310033B1 (enExample) |
| JP (3) | JP2011522840A (enExample) |
| KR (1) | KR20110036039A (enExample) |
| CN (1) | CN102123728B (enExample) |
| AT (2) | AT509611B1 (enExample) |
| AU (1) | AU2009257168B2 (enExample) |
| BR (1) | BRPI0915136A2 (enExample) |
| CA (1) | CA2723967A1 (enExample) |
| ES (1) | ES2392789T3 (enExample) |
| IL (1) | IL209894A (enExample) |
| MX (1) | MX2010013657A (enExample) |
| RU (1) | RU2491953C2 (enExample) |
| WO (1) | WO2009149485A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120328605A1 (en) * | 2010-10-27 | 2012-12-27 | Daniel Larocque | Compositions and uses |
| EP2686346B1 (en) * | 2011-03-16 | 2016-12-14 | Probiodrug AG | Diagnostic antibody assay |
| GB201113570D0 (en) | 2011-08-05 | 2011-09-21 | Glaxosmithkline Biolog Sa | Vaccine |
| EP2579042B1 (en) | 2011-10-04 | 2014-07-09 | Affiris AG | Method for detecting Aß-specific antibodies in a biological sample |
| EP2659908A1 (en) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
| US9102752B2 (en) | 2013-03-15 | 2015-08-11 | United Biomedical, Inc. | Peptide vaccine for prevention and immunotherapy of dementia of the Alzheimer's type |
| EP2787347A1 (en) | 2013-04-03 | 2014-10-08 | Affiris AG | Method for detecting Aß-specific antibodies in a biological sample |
| EP3137094B1 (en) | 2014-04-29 | 2022-12-07 | ADvantage Therapeutics, Inc. | Treatment and prevention of alzheimer's disease (ad) |
| WO2015165964A1 (en) * | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| WO2015165961A1 (en) | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| CN108350052A (zh) | 2015-11-09 | 2018-07-31 | 英属哥伦比亚大学 | 淀粉样蛋白β中间区域中的表位及其构象选择性抗体 |
| JP7452829B2 (ja) | 2015-11-09 | 2024-03-19 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | アミロイドベータのエピトープおよびそれに対する抗体 |
| EP3374379A4 (en) | 2015-11-09 | 2019-05-15 | The University Of British Columbia | N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES |
| WO2018014126A1 (en) | 2016-07-18 | 2018-01-25 | The University Of British Columbia | Antibodies to amyloid beta |
| US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
| CA3070085A1 (en) | 2017-07-18 | 2019-01-24 | Promis Neurosciences Inc. | Antibodies to amyloid beta |
| US12286469B2 (en) | 2017-07-18 | 2025-04-29 | The University Of British Columbia | Humanized antibodies binding to amyloid-beta (A-beta) |
| RU2679080C1 (ru) * | 2018-04-17 | 2019-02-05 | Александр Олегович Морозов | Пептид и способ лечения болезни альцгеймера |
| US20250186595A1 (en) | 2022-02-28 | 2025-06-12 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
| CN115925987A (zh) * | 2022-02-28 | 2023-04-07 | 安域生物科技(杭州)有限公司 | 基于β-淀粉样蛋白修饰的抗原多肽及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5780587A (en) * | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| AU744044B2 (en) * | 1998-04-06 | 2002-02-14 | Advanced Immunit, Inc. | Short peptides for treatment of neurological degenerative diseases |
| NO314086B1 (no) * | 1998-05-08 | 2003-01-27 | Gemvax As | Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til |
| CA2325600A1 (en) * | 1998-05-21 | 1999-11-25 | The University Of Tennessee Research Corporation | Methods for amyloid removal using anti-amyloid antibodies |
| US7504490B1 (en) * | 1998-10-16 | 2009-03-17 | Oscient Pharmaceuticals Corporation | Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics |
| US20040067535A1 (en) * | 2002-10-03 | 2004-04-08 | Life Sciences Development Corp. | Alzheimer's disease linked genes |
| CN101103969A (zh) * | 2002-12-24 | 2008-01-16 | 神经化学(国际)有限公司 | 治疗β淀粉样蛋白相关疾病的治疗性制品 |
| AT413945B (de) | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| EP1440981A3 (en) * | 2003-01-21 | 2005-11-23 | Research Association for Biotechnology | Full-length human cdna |
| US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| AT413946B (de) * | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| CN101137394A (zh) * | 2004-10-25 | 2008-03-05 | 默克制药公司 | 抗addl抗体及其应用 |
| EP1907416A2 (en) * | 2005-06-17 | 2008-04-09 | EPFL Ecole Polytechnique Fédérale de Lausanne | Switch-peptides as tool for the study of fibrillogenesis |
| EP2808032B1 (en) * | 2005-12-12 | 2018-08-01 | AC Immune S.A. | A beta 1-42 specific monoclonal antibodies with therapeutic properties |
| CA2638775A1 (en) * | 2006-02-22 | 2007-08-30 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Peptide vaccine for inducing production of anti-amyloid-.beta.-peptide antibody |
-
2008
- 2008-06-12 AT ATA416/2010A patent/AT509611B1/de not_active IP Right Cessation
- 2008-06-12 AT AT0095208A patent/AT506820B1/de not_active IP Right Cessation
-
2009
- 2009-06-12 KR KR1020117000810A patent/KR20110036039A/ko not_active Ceased
- 2009-06-12 JP JP2011512780A patent/JP2011522840A/ja active Pending
- 2009-06-12 WO PCT/AT2009/000235 patent/WO2009149485A2/en not_active Ceased
- 2009-06-12 EP EP09761152A patent/EP2310033B1/en active Active
- 2009-06-12 US US12/997,673 patent/US8409581B2/en not_active Expired - Fee Related
- 2009-06-12 MX MX2010013657A patent/MX2010013657A/es active IP Right Grant
- 2009-06-12 AU AU2009257168A patent/AU2009257168B2/en not_active Ceased
- 2009-06-12 RU RU2011100125/15A patent/RU2491953C2/ru not_active IP Right Cessation
- 2009-06-12 CN CN200980131376.3A patent/CN102123728B/zh not_active Expired - Fee Related
- 2009-06-12 BR BRPI0915136A patent/BRPI0915136A2/pt not_active IP Right Cessation
- 2009-06-12 ES ES09761152T patent/ES2392789T3/es active Active
- 2009-06-12 CA CA2723967A patent/CA2723967A1/en not_active Abandoned
-
2010
- 2010-12-09 IL IL209894A patent/IL209894A/en not_active IP Right Cessation
-
2014
- 2014-03-31 JP JP2014073229A patent/JP5984867B2/ja not_active Expired - Fee Related
- 2014-12-25 JP JP2014263345A patent/JP5989074B2/ja not_active Expired - Fee Related
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