CA2723967A1 - Compounds for treating amyloidoses - Google Patents
Compounds for treating amyloidoses Download PDFInfo
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- CA2723967A1 CA2723967A1 CA2723967A CA2723967A CA2723967A1 CA 2723967 A1 CA2723967 A1 CA 2723967A1 CA 2723967 A CA2723967 A CA 2723967A CA 2723967 A CA2723967 A CA 2723967A CA 2723967 A1 CA2723967 A1 CA 2723967A1
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
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- Veterinary Medicine (AREA)
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- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| ATA952/2008 | 2008-06-12 | ||
| AT0095208A AT506820B1 (de) | 2008-06-12 | 2008-06-12 | Vakzine gegen alzheimer-krankheit |
| PCT/AT2009/000235 WO2009149485A2 (en) | 2008-06-12 | 2009-06-12 | Compounds for treating amyloidoses |
Publications (1)
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|---|---|
| CA2723967A1 true CA2723967A1 (en) | 2009-12-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2723967A Abandoned CA2723967A1 (en) | 2008-06-12 | 2009-06-12 | Compounds for treating amyloidoses |
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| EP (1) | EP2310033B1 (enExample) |
| JP (3) | JP2011522840A (enExample) |
| KR (1) | KR20110036039A (enExample) |
| CN (1) | CN102123728B (enExample) |
| AT (2) | AT509611B1 (enExample) |
| AU (1) | AU2009257168B2 (enExample) |
| BR (1) | BRPI0915136A2 (enExample) |
| CA (1) | CA2723967A1 (enExample) |
| ES (1) | ES2392789T3 (enExample) |
| IL (1) | IL209894A (enExample) |
| MX (1) | MX2010013657A (enExample) |
| RU (1) | RU2491953C2 (enExample) |
| WO (1) | WO2009149485A2 (enExample) |
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| US20120328605A1 (en) * | 2010-10-27 | 2012-12-27 | Daniel Larocque | Compositions and uses |
| EP2686346B1 (en) * | 2011-03-16 | 2016-12-14 | Probiodrug AG | Diagnostic antibody assay |
| GB201113570D0 (en) | 2011-08-05 | 2011-09-21 | Glaxosmithkline Biolog Sa | Vaccine |
| EP2579042B1 (en) | 2011-10-04 | 2014-07-09 | Affiris AG | Method for detecting Aß-specific antibodies in a biological sample |
| EP2659908A1 (en) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
| US9102752B2 (en) | 2013-03-15 | 2015-08-11 | United Biomedical, Inc. | Peptide vaccine for prevention and immunotherapy of dementia of the Alzheimer's type |
| EP2787347A1 (en) | 2013-04-03 | 2014-10-08 | Affiris AG | Method for detecting Aß-specific antibodies in a biological sample |
| EP3137094B1 (en) | 2014-04-29 | 2022-12-07 | ADvantage Therapeutics, Inc. | Treatment and prevention of alzheimer's disease (ad) |
| WO2015165964A1 (en) * | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| WO2015165961A1 (en) | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| CN108350052A (zh) | 2015-11-09 | 2018-07-31 | 英属哥伦比亚大学 | 淀粉样蛋白β中间区域中的表位及其构象选择性抗体 |
| JP7452829B2 (ja) | 2015-11-09 | 2024-03-19 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | アミロイドベータのエピトープおよびそれに対する抗体 |
| EP3374379A4 (en) | 2015-11-09 | 2019-05-15 | The University Of British Columbia | N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES |
| WO2018014126A1 (en) | 2016-07-18 | 2018-01-25 | The University Of British Columbia | Antibodies to amyloid beta |
| US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
| CA3070085A1 (en) | 2017-07-18 | 2019-01-24 | Promis Neurosciences Inc. | Antibodies to amyloid beta |
| US12286469B2 (en) | 2017-07-18 | 2025-04-29 | The University Of British Columbia | Humanized antibodies binding to amyloid-beta (A-beta) |
| RU2679080C1 (ru) * | 2018-04-17 | 2019-02-05 | Александр Олегович Морозов | Пептид и способ лечения болезни альцгеймера |
| US20250186595A1 (en) | 2022-02-28 | 2025-06-12 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
| CN115925987A (zh) * | 2022-02-28 | 2023-04-07 | 安域生物科技(杭州)有限公司 | 基于β-淀粉样蛋白修饰的抗原多肽及其应用 |
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| US5780587A (en) * | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| AU744044B2 (en) * | 1998-04-06 | 2002-02-14 | Advanced Immunit, Inc. | Short peptides for treatment of neurological degenerative diseases |
| NO314086B1 (no) * | 1998-05-08 | 2003-01-27 | Gemvax As | Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til |
| CA2325600A1 (en) * | 1998-05-21 | 1999-11-25 | The University Of Tennessee Research Corporation | Methods for amyloid removal using anti-amyloid antibodies |
| US7504490B1 (en) * | 1998-10-16 | 2009-03-17 | Oscient Pharmaceuticals Corporation | Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics |
| US20040067535A1 (en) * | 2002-10-03 | 2004-04-08 | Life Sciences Development Corp. | Alzheimer's disease linked genes |
| CN101103969A (zh) * | 2002-12-24 | 2008-01-16 | 神经化学（国际）有限公司 | 治疗β淀粉样蛋白相关疾病的治疗性制品 |
| AT413945B (de) | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| EP1440981A3 (en) * | 2003-01-21 | 2005-11-23 | Research Association for Biotechnology | Full-length human cdna |
| US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| AT413946B (de) * | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| CN101137394A (zh) * | 2004-10-25 | 2008-03-05 | 默克制药公司 | 抗addl抗体及其应用 |
| EP1907416A2 (en) * | 2005-06-17 | 2008-04-09 | EPFL Ecole Polytechnique Fédérale de Lausanne | Switch-peptides as tool for the study of fibrillogenesis |
| EP2808032B1 (en) * | 2005-12-12 | 2018-08-01 | AC Immune S.A. | A beta 1-42 specific monoclonal antibodies with therapeutic properties |
| CA2638775A1 (en) * | 2006-02-22 | 2007-08-30 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Peptide vaccine for inducing production of anti-amyloid-.beta.-peptide antibody |
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| ES2392789T3 (es) | 2012-12-13 |
| BRPI0915136A2 (pt) | 2019-09-24 |
| JP2014139227A (ja) | 2014-07-31 |
| MX2010013657A (es) | 2011-04-11 |
| JP2011522840A (ja) | 2011-08-04 |
| EP2310033A2 (en) | 2011-04-20 |
| AT506820B1 (de) | 2011-07-15 |
| AU2009257168A1 (en) | 2009-12-17 |
| CN102123728A (zh) | 2011-07-13 |
| RU2011100125A (ru) | 2012-07-20 |
| AU2009257168B2 (en) | 2015-01-22 |
| WO2009149485A2 (en) | 2009-12-17 |
| EP2310033B1 (en) | 2012-09-05 |
| AT509611A1 (de) | 2011-10-15 |
| IL209894A0 (en) | 2011-02-28 |
| JP5984867B2 (ja) | 2016-09-06 |
| RU2491953C2 (ru) | 2013-09-10 |
| US8409581B2 (en) | 2013-04-02 |
| WO2009149485A3 (en) | 2010-06-10 |
| AT509611B1 (de) | 2012-04-15 |
| KR20110036039A (ko) | 2011-04-06 |
| IL209894A (en) | 2015-08-31 |
| US20110171243A1 (en) | 2011-07-14 |
| JP5989074B2 (ja) | 2016-09-07 |
| JP2015110588A (ja) | 2015-06-18 |
| CN102123728B (zh) | 2017-05-31 |
| AT506820A1 (de) | 2009-12-15 |
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