|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
RU2644243C2
(ru)
*
|
2011-10-20 |
2018-02-08 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы к cd22
|
|
EP2855666B1
(en)
|
2012-05-25 |
2019-12-04 |
Cellectis |
Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells
|
|
EP2862875B1
(en)
|
2012-06-14 |
2023-09-06 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING MODIFIED Fc REGION
|
|
RU2658485C2
(ru)
|
2012-10-24 |
2018-06-21 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы м971
|
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
ES2776698T3
(es)
|
2012-12-20 |
2020-07-31 |
Purdue Research Foundation |
Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
|
|
EP2958942B1
(en)
|
2013-02-20 |
2020-06-03 |
Novartis AG |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
ES2760023T3
(es)
|
2013-02-20 |
2020-05-12 |
Univ Pennsylvania |
Tratamiento del cáncer utilizando receptor de antígeno quimérico anti-EGFRvIII humanizado
|
|
AU2014240083C1
(en)
|
2013-03-15 |
2019-10-24 |
Celgene Corporation |
Modified T lymphocytes
|
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
WO2014160627A1
(en)
|
2013-03-25 |
2014-10-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-cd276 polypeptides, proteins, and chimeric antigen receptors
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
US9629877B2
(en)
|
2013-05-14 |
2017-04-25 |
Board Of Regents, The University Of Texas System |
Human application of engineered chimeric antigen receptor (CAR) T-cells
|
|
SG11201509609SA
(en)
|
2013-05-24 |
2015-12-30 |
Univ Texas |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
CA3173052A1
(en)
|
2013-08-30 |
2015-03-05 |
Board Of Regents, The University Of Texas System |
Administration of kynurenine depleting enzymes for tumor therapy
|
|
EP4269421A3
(en)
|
2013-10-11 |
2023-12-27 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Tem8 antibodies and their use
|
|
WO2015069922A2
(en)
|
2013-11-06 |
2015-05-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
|
CN103589742A
(zh)
*
|
2013-11-07 |
2014-02-19 |
申峰 |
嵌合体抗原受体胞内段的基因及其编码蛋白
|
|
KR102813659B1
(ko)
|
2013-11-11 |
2025-05-28 |
추가이 세이야쿠 가부시키가이샤 |
개변된 항체 가변영역을 포함하는 항원 결합 분자
|
|
WO2015077789A2
(en)
|
2013-11-25 |
2015-05-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors to control hiv infection
|
|
RU2714902C2
(ru)
|
2013-12-19 |
2020-02-20 |
Новартис Аг |
Химерные рецепторы антигена против мезотелина человека и их применение
|
|
EP3087101B1
(en)
|
2013-12-20 |
2024-06-05 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
EP4303229A3
(en)
|
2014-01-21 |
2024-04-17 |
Novartis AG |
Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
|
|
WO2015120187A1
(en)
|
2014-02-05 |
2015-08-13 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants
|
|
RU2021123419A
(ru)
|
2014-02-14 |
2021-10-22 |
Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем |
Химерные антигенные рецепторы и способы их получения
|
|
CN103820393B
(zh)
*
|
2014-02-24 |
2016-09-07 |
西比曼生物科技（上海）有限公司 |
工程化cd20靶向性的nkt细胞及其制备方法和应用
|
|
ES2876263T3
(es)
|
2014-04-07 |
2021-11-12 |
Novartis Ag |
Tratamiento del cáncer usando receptor de antígeno quimérico anti-cd19
|
|
NZ739448A
(en)
|
2014-04-10 |
2019-10-25 |
Seattle Children’S Hospital Dba Seattle Children’S Res Institute |
Transgene genetic tags and methods of use
|
|
SG11201700416TA
(en)
|
2014-07-21 |
2017-02-27 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
EP3171882A1
(en)
|
2014-07-21 |
2017-05-31 |
Novartis AG |
Treatment of cancer using a cll-1 chimeric antigen receptor
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
US10174095B2
(en)
|
2014-07-21 |
2019-01-08 |
Novartis Ag |
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
|
|
WO2016016344A1
(en)
*
|
2014-07-29 |
2016-02-04 |
Cellectis |
Ror1(ntrkr1)specific chimeric antigen receptors for cancer immunotherapy
|
|
DK3183268T3
(da)
|
2014-08-19 |
2020-05-11 |
Univ Pennsylvania |
Behandling af cancer ved anvendelse af en cd123-kimær antigenreceptor
|
|
ES2987380T3
(es)
|
2014-08-29 |
2024-11-14 |
Univ Texas |
Administración de enzimas de depleción de la quinurenina para la terapia tumoral
|
|
DK3189073T4
(da)
|
2014-09-04 |
2025-08-18 |
Cellectis |
Trofoblastglykoprotein (5t4, tpbg)-specifikke kimære antigenreceptorer til cancerimmunterapi
|
|
ES2875057T3
(es)
|
2014-09-17 |
2021-11-08 |
Us Health |
Anticuerpos anti-CD276 (B7H3)
|
|
KR20210149228A
(ko)
|
2014-09-17 |
2021-12-08 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
US10774388B2
(en)
|
2014-10-08 |
2020-09-15 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
PL3207130T3
(pl)
|
2014-10-14 |
2020-02-28 |
Halozyme, Inc. |
Kompozycje deaminazy adenozyny 2 (ada2), jej warianty i sposoby ich zastosowania
|
|
AU2015343013B2
(en)
|
2014-11-05 |
2020-07-16 |
Board Of Regents, The University Of Texas System |
Gene modified immune effector cells and engineered cells for expansion of immune effector cells
|
|
WO2016073629A1
(en)
|
2014-11-05 |
2016-05-12 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (car) to selectively target protein complexes
|
|
US11154615B2
(en)
|
2014-11-11 |
2021-10-26 |
Chugai Seiyaku Kabushiki Kaisha |
Library of antigen-binding molecules including modified antibody variable region
|
|
WO2016090190A1
(en)
|
2014-12-03 |
2016-06-09 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
DK3597663T3
(da)
|
2014-12-08 |
2022-06-27 |
Us Health |
Kimære antigenreceptorer af anti-cd70
|
|
KR102376244B1
(ko)
|
2014-12-24 |
2022-03-21 |
오토러스 리미티드 |
세포
|
|
RU2751362C2
(ru)
|
2014-12-29 |
2021-07-13 |
Новартис Аг |
Способы получения экспрессирующих химерный антигенный рецептор клеток
|
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
|
CA2973529A1
(en)
|
2015-01-26 |
2016-08-04 |
Cellectis |
Cll1-specific multi-chain chimeric antigen receptor
|
|
CN107683289B
(zh)
|
2015-01-26 |
2021-08-06 |
芝加哥大学 |
IL13Rα2结合剂和其在癌症治疗中的用途
|
|
WO2016123143A1
(en)
|
2015-01-26 |
2016-08-04 |
The University Of Chicago |
CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Rα2
|
|
CN107429254B
(zh)
|
2015-01-30 |
2021-10-15 |
加利福尼亚大学董事会 |
原代造血细胞中的蛋白递送
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
WO2016130516A1
(en)
|
2015-02-09 |
2016-08-18 |
Research Development Foundation |
Engineered immunoglobulin fc polypeptides displaying improved complement activation
|
|
WO2016149578A1
(en)
|
2015-03-19 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Dual specific anti-cd22-anti-cd19 chimeric antigen receptors
|
|
ES2789348T3
(es)
|
2015-03-20 |
2020-10-26 |
Us Health |
Anticuerpos neutralizantes para GP120 y sus usos
|
|
HUE059218T2
(hu)
*
|
2015-04-08 |
2022-11-28 |
Novartis Ag |
CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel
|
|
US11896614B2
(en)
|
2015-04-17 |
2024-02-13 |
Novartis Ag |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
GB201507111D0
(en)
*
|
2015-04-27 |
2015-06-10 |
Ucl Business Plc |
Nucleic acid construct
|
|
KR102526538B1
(ko)
|
2015-06-10 |
2023-04-28 |
이뮤너티바이오, 인크. |
암을 치료하기 위한 변형된 nk-92 세포
|
|
EP3310805B1
(en)
|
2015-06-19 |
2021-02-17 |
Kobold, Sebastian |
Pd-1-cd28 fusion proteins and their use in medicine
|
|
JP2018518972A
(ja)
|
2015-06-26 |
2018-07-19 |
ユニバーシティ オブ サザン カリフォルニア |
腫瘍特異的活性化のためのマスキングキメラ抗原受容体ｔ細胞
|
|
SG10201912978PA
(en)
|
2015-07-21 |
2020-02-27 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
WO2017027392A1
(en)
|
2015-08-07 |
2017-02-16 |
Novartis Ag |
Treatment of cancer using chimeric cd3 receptor proteins
|
|
WO2017035251A1
(en)
|
2015-08-25 |
2017-03-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cells modified to overexpress c-myb
|
|
US10526408B2
(en)
|
2015-08-28 |
2020-01-07 |
Research Development Foundation |
Engineered antibody FC variants
|
|
CN108780084B
(zh)
|
2015-09-03 |
2022-07-22 |
诺华股份有限公司 |
预测细胞因子释放综合征的生物标志物
|
|
EP3347375B1
(en)
*
|
2015-09-10 |
2020-12-23 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Anti-cd276 chimeric antigen receptors
|
|
AU2016335750B2
(en)
|
2015-10-07 |
2023-05-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
|
US11723922B2
(en)
|
2015-10-16 |
2023-08-15 |
Ludwig-Maximilians-Universität München |
CXCR6-transduced T cells for targeted tumor therapy
|
|
WO2017070042A1
(en)
|
2015-10-20 |
2017-04-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing t cell populations using akt inhibitors
|
|
WO2017075147A1
(en)
|
2015-10-27 |
2017-05-04 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
CN108699557B
(zh)
|
2015-12-04 |
2025-08-15 |
诺华股份有限公司 |
用于免疫肿瘤学的组合物和方法
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
WO2017139199A1
(en)
|
2016-02-10 |
2017-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Inducible arginase
|
|
WO2017151860A1
(en)
|
2016-03-02 |
2017-09-08 |
Broard Of Regents, The University Of Texas System |
Human kynureninase enzyme variants having improved pharmacological properties
|
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
JP7282521B2
(ja)
|
2016-04-08 |
2023-05-29 |
パーデュー・リサーチ・ファウンデイション |
Ｃａｒ ｔ細胞療法のための方法および組成物
|
|
EP3443001B1
(en)
|
2016-04-11 |
2025-04-30 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
|
CN107298715B
(zh)
*
|
2016-04-15 |
2021-05-04 |
阿思科力(苏州)生物科技有限公司 |
Slit2D2-嵌合抗原受体及其应用
|
|
CN105968210B
(zh)
*
|
2016-05-13 |
2019-05-31 |
深圳生创精准医疗科技有限公司 |
靶向cd22的强杀伤性嵌合抗原受体t细胞及其在制备治疗肿瘤的药物中的用途
|
|
CN106167527A
(zh)
*
|
2016-06-13 |
2016-11-30 |
长沙郝怡雅医药科技有限公司 |
一种融合蛋白
|
|
GB201610512D0
(en)
*
|
2016-06-16 |
2016-08-03 |
Autolus Ltd |
Chimeric antigen receptor
|
|
MX2018015414A
(es)
|
2016-06-30 |
2019-08-01 |
Hoffmann La Roche |
Terapia de célula t adoptiva mejorada.
|
|
JP6908710B2
(ja)
|
2016-09-21 |
2021-07-28 |
ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
ケモカイン受容体ｃｃｒ４を標的にするキメラ抗原受容体（ｃａｒ）およびその使用
|
|
CA3037882A1
(en)
|
2016-09-23 |
2018-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of preparing an isolated population of dendritic cells and methods of treating cancer using same
|
|
CN109804064A
(zh)
|
2016-09-29 |
2019-05-24 |
南克维斯特公司 |
具有降低的免疫原性的hla i类缺陷的nk-92细胞
|
|
CA3039646A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
CA3037387A1
(en)
|
2016-10-13 |
2018-04-19 |
Juno Therapeutics, Inc. |
Immunotherapy methods and compositions involving tryptophan metabolic pathway modulators
|
|
CN107964549B
(zh)
*
|
2016-10-20 |
2020-12-08 |
上海恒润达生生物科技有限公司 |
靶向cd22的嵌合抗原受体及其用途
|
|
JP7100028B2
(ja)
|
2016-10-20 |
2022-07-12 |
セルジーン コーポレイション |
セレブロン系のヘテロ二量体化可能なキメラ抗原受容体
|
|
US12215349B2
(en)
|
2016-12-13 |
2025-02-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of preparing an isolated or purified population of thymic emigrant cells and methods of treatment using same
|
|
CN110168078B
(zh)
|
2017-01-06 |
2024-05-14 |
免疫生物公司 |
具有降低的cd96/tigit表达的遗传修饰的nk-92细胞
|
|
EP3882265B1
(en)
|
2017-01-09 |
2022-11-02 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-mesothelin immunotherapy
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
|
CA3053803A1
(en)
|
2017-02-24 |
2018-08-30 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
|
WO2018160622A1
(en)
|
2017-02-28 |
2018-09-07 |
Endocyte, Inc. |
Compositions and methods for car t cell therapy
|
|
CA3055202A1
(en)
*
|
2017-03-03 |
2018-09-07 |
Obsidian Therapeutics, Inc. |
Cd19 compositions and methods for immunotherapy
|
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
|
CN110832075A
(zh)
|
2017-03-22 |
2020-02-21 |
诺华股份有限公司 |
用于免疫肿瘤学的组合物和方法
|
|
WO2018181207A1
(ja)
*
|
2017-03-27 |
2018-10-04 |
ノイルイミューン・バイオテック株式会社 |
キメラ抗原受容体
|
|
WO2018178377A1
(en)
|
2017-03-31 |
2018-10-04 |
Cellectis Sa |
Universal anti-cd22 chimeric antigen receptor engineered immune cells
|
|
CA3057505A1
(en)
|
2017-03-31 |
2018-10-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
|
CA3059643A1
(en)
|
2017-04-13 |
2018-10-18 |
Cellectis |
New sequence specific reagents targeting ccr5 in primary hematopoietic cells
|
|
AU2018256436B2
(en)
|
2017-04-19 |
2024-12-05 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
AU2018269194B2
(en)
|
2017-05-15 |
2025-05-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bicistronic chimeric antigen receptors and their uses
|
|
CA3065126A1
(en)
*
|
2017-06-01 |
2018-12-06 |
Innovative Cellular Therapeutics CO., LTD. |
Chimeric antigen receptor cell preparation and uses thereof
|
|
US12384830B2
(en)
|
2017-06-02 |
2025-08-12 |
Regents Of The University Of Minnesota |
Compositions and methods for improving immunotherapy
|
|
EP3635098B1
(en)
|
2017-06-05 |
2021-09-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T-cells modified to overexpress phf19
|
|
US20200197533A1
(en)
*
|
2017-06-22 |
2020-06-25 |
University Of Southern California |
Combination cancer therapy using chimeric antigen receptor engineered natural killer cells as chemotherapeutic drug carriers
|
|
CA3067914A1
(en)
|
2017-06-30 |
2019-01-03 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
US11235004B2
(en)
|
2017-06-30 |
2022-02-01 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Lymphocyte cell lines and uses thereof
|
|
KR20200055037A
(ko)
|
2017-09-19 |
2020-05-20 |
메사추세츠 인스티튜트 오브 테크놀로지 |
키메라 항원 수용체 t 세포 요법을 위한 조성물 및 그의 용도
|
|
WO2019075055A1
(en)
|
2017-10-11 |
2019-04-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
METHODS FOR PRODUCING T-CELL POPULATIONS USING P38 MAPK INHIBITORS
|
|
AU2018352245B2
(en)
*
|
2017-10-16 |
2025-07-03 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD22 immunotherapy
|
|
WO2019079486A1
(en)
*
|
2017-10-18 |
2019-04-25 |
Intrexon Corporation |
POLYPEPTIDE COMPOSITIONS COMPRISING SPACERS
|
|
CA3079407A1
(en)
|
2017-10-18 |
2019-04-25 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
WO2019084284A1
(en)
|
2017-10-27 |
2019-05-02 |
Coneksis, Inc. |
NK CELLS FOR USE IN THE TREATMENT OF CANCER IN DOGS
|
|
WO2019111871A1
(en)
|
2017-12-05 |
2019-06-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule comprising altered antibody variable region binding cd3 and cd137
|
|
WO2019117976A1
(en)
|
2017-12-17 |
2019-06-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Peptide hydrogels and use thereof
|
|
CN112292138A
(zh)
|
2018-01-22 |
2021-01-29 |
西雅图儿童医院（Dba西雅图儿童研究所） |
Car t细胞的使用方法
|
|
CN111670246A
(zh)
|
2018-01-31 |
2020-09-15 |
南克维斯特公司 |
5%人白蛋白在洗涤和收获培养基中的用途
|
|
SG11202007426XA
(en)
|
2018-02-06 |
2020-09-29 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
CN118374524A
(zh)
|
2018-02-09 |
2024-07-23 |
美国卫生和人力服务部 |
拴系白细胞介素-15和白细胞介素-21
|
|
EP3749687A4
(en)
|
2018-02-11 |
2021-12-29 |
Memorial Sloan Kettering Cancer Center |
Non-hla restricted t cell receptors and uses thereof
|
|
EP3755349A4
(en)
|
2018-02-21 |
2021-11-17 |
Board of Regents, The University of Texas System |
PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES
|
|
WO2019165237A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
CA3093078A1
(en)
|
2018-03-06 |
2019-09-12 |
The Trustees Of The University Of Pennsylvania |
Prostate-specific membrane antigen cars and methods of use thereof
|
|
WO2019177986A1
(en)
|
2018-03-12 |
2019-09-19 |
Nantkwest, Inc. |
Use of cd33car modified high affinity nk cells (t-hank) to reduce myeloid-derived suppressor cells suppressor activity (or reduce negative impact on nk cell activity)
|
|
KR20210018797A
(ko)
*
|
2018-04-10 |
2021-02-18 |
암젠 인크 |
Dll3에 대한 키메라 수용체 및 이의 사용 방법
|
|
MX2020010808A
(es)
|
2018-04-13 |
2021-03-02 |
Sangamo Therapeutics France |
Receptor de antigeno quimerico especifico para el receptor de interleucina-23.
|
|
WO2019204269A1
(en)
|
2018-04-16 |
2019-10-24 |
Board Of Regents, The University Of Texas System |
Human kynureninase enzymes and uses thereof
|
|
US12415845B2
(en)
|
2018-04-24 |
2025-09-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof
|
|
ES2925553T3
(es)
|
2018-05-22 |
2022-10-18 |
Immunitybio Inc |
Optimización del crecimiento de células NK-92 mediante el uso de poloxámero
|
|
US20210198628A1
(en)
|
2018-05-22 |
2021-07-01 |
Nantkwest, Inc. |
Basal media for growing nk-92 cells
|
|
IL321548A
(en)
|
2018-05-22 |
2025-08-01 |
Immunitybio Inc |
Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
|
|
MY208825A
(en)
|
2018-06-13 |
2025-05-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
|
WO2020014245A1
(en)
|
2018-07-10 |
2020-01-16 |
Nantkwest, Inc. |
Cryopreservation
|
|
IL319500A
(en)
|
2018-07-10 |
2025-05-01 |
Immunitybio Inc |
Production of CIK NKT cells from cord blood
|
|
EP3820903A1
(en)
|
2018-07-12 |
2021-05-19 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Affinity matured cd22-specific monoclonal antibody and uses thereof
|
|
CN119752802A
(zh)
|
2018-08-01 |
2025-04-04 |
南克维斯特公司 |
用于免疫疗法的基因修饰的包含归巢受体或细胞因子和嵌合抗原受体的四顺反子系统
|
|
WO2020028654A1
(en)
|
2018-08-01 |
2020-02-06 |
Nantkwest, Inc. |
Combined invasion and cytotoxicity assay using chemokine secreting target cells
|
|
CN112513069A
(zh)
|
2018-08-01 |
2021-03-16 |
南克维斯特公司 |
具有对于验证的靶标的二次归巢激活的趋化因子反应性激活的自然杀伤细胞
|
|
SG11202101152QA
(en)
|
2018-08-03 |
2021-03-30 |
Chugai Pharmaceutical Co Ltd |
Antigen-binding molecule containing two antigen-binding domains that are linked to each other
|
|
CN109022363A
(zh)
*
|
2018-08-15 |
2018-12-18 |
马晓冬 |
一种基于PiggyBac载体的CD-133-CAR-T系统构建方法
|
|
KR20210068478A
(ko)
|
2018-09-28 |
2021-06-09 |
메사추세츠 인스티튜트 오브 테크놀로지 |
콜라겐-국재화된 면역조정성 분자 및 그의 방법
|
|
AU2018447127A1
(en)
|
2018-10-22 |
2021-05-27 |
Shanghai GenBase Biotechnology Co., Ltd. |
Anti-CLDN128.2 antibody and uses thereof
|
|
US12109238B2
(en)
|
2018-11-06 |
2024-10-08 |
Immunitybio, Inc. |
Chimeric antigen receptor-modified NK-92 cells
|
|
WO2020096646A1
(en)
|
2018-11-06 |
2020-05-14 |
Nantkwest, Inc. |
Chimeric antigen receptor-modified nk-92 cells
|
|
EP3886873A1
(en)
|
2018-11-26 |
2021-10-06 |
ImmunityBio, Inc. |
Il-2 dependent nk-92 cells with stable fc receptor expression
|
|
EP3670530A1
(en)
|
2018-12-18 |
2020-06-24 |
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft |
Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies
|
|
CA3128971A1
(en)
|
2019-03-08 |
2020-09-17 |
Klinikum Der Universitat Munchen |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
|
EP3986427A1
(en)
|
2019-06-24 |
2022-04-27 |
Childrens Hospital Los Angeles |
Bcl11b overexpression to enhance human thymopoiesis and t cell function
|
|
EP3990491A1
(en)
|
2019-06-26 |
2022-05-04 |
Massachusetts Institute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
MX2022000174A
(es)
|
2019-07-02 |
2022-05-20 |
Us Health |
Anticuerpos monoclonales que se enlazan a egfrviii y sus usos.
|
|
CN114286683B
(zh)
*
|
2019-07-17 |
2024-10-01 |
新加坡国立大学 |
由免疫细胞合成和分泌的功能性结合物
|
|
US12180283B2
(en)
|
2019-08-01 |
2024-12-31 |
Immunitybio, Inc. |
Anti-B7-H4 chimeric antigen receptor-modified NK-92 cells
|
|
AU2020345943A1
(en)
|
2019-09-10 |
2022-03-31 |
Obsidian Therapeutics, Inc. |
CA2-IL15 fusion proteins for tunable regulation
|
|
WO2021051390A1
(zh)
|
2019-09-20 |
2021-03-25 |
上海吉倍生物技术有限公司 |
靶向bcma的抗体及嵌合抗原受体
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
IL292924A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|
|
US11230699B2
(en)
|
2020-01-28 |
2022-01-25 |
Immunitybio, Inc. |
Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors
|
|
KR20240096884A
(ko)
|
2020-03-10 |
2024-06-26 |
매사추세츠 인스티튜트 오브 테크놀로지 |
조작된 기억-유사 nk 세포 및 이의 조성물을 생성하기 위한 방법
|
|
EP4118112A1
(en)
|
2020-03-10 |
2023-01-18 |
Massachusetts Institute of Technology |
Compositions and methods for immunotherapy of npm1c-positive cancer
|
|
AR121695A1
(es)
|
2020-03-31 |
2022-06-29 |
Chugai Pharmaceutical Co Ltd |
Moléculas de unión al antígeno multiespecíficas dirigidas a dll3 y sus usos
|
|
CN115335405B
(zh)
*
|
2020-04-02 |
2024-02-23 |
南京驯鹿生物技术股份有限公司 |
全人源抗人cd22的嵌合抗原受体及其应用
|
|
CN111484562B
(zh)
*
|
2020-04-25 |
2021-08-20 |
首都医科大学附属北京朝阳医院 |
一种靶向cd22蛋白的抗体、嵌合抗原受体和药物
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US12433954B2
(en)
|
2020-05-01 |
2025-10-07 |
Massachusetts Institute Of Technology |
Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs
|
|
BR112022024027A2
(pt)
|
2020-05-27 |
2023-02-07 |
Antion Biosciences Sa |
Moléculas adaptadoras para redirecionar células t car para um antígeno de interesse
|
|
US20230258635A1
(en)
|
2020-09-08 |
2023-08-17 |
The United States Of America,As Represented By The Secretary,Department Of Health And Human Services |
T cell phenotypes associated with response to adoptive cell therapy
|
|
EP4243937A2
(en)
|
2020-11-13 |
2023-09-20 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Enhanced antigen reactivity of immune cells expressing a mutant non-signaling cd3 zeta chain
|
|
MX2023005491A
(es)
|
2020-11-24 |
2023-08-09 |
Lyell Immunopharma Inc |
Métodos de preparación de células t rejuvenecidas, composiciones que las comprenden y métodos de uso de las mismas.
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
EP4255922A1
(en)
|
2020-12-03 |
2023-10-11 |
Century Therapeutics, Inc. |
Genetically engineered cells and uses thereof
|
|
JP2024500847A
(ja)
|
2020-12-18 |
2024-01-10 |
センチュリー セラピューティクス，インコーポレイテッド |
適合可能な受容体特異性を有するキメラ抗原受容体システム
|
|
JP7734753B2
(ja)
|
2021-03-05 |
2025-09-05 |
シャンハイ、ケンパーソー、バイオテクノロジー、カンパニー、リミテッド |
抗ｃｌｄｎ６抗体およびその使用
|
|
US20240269182A1
(en)
*
|
2021-05-27 |
2024-08-15 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Modified Chimeric Antigen Receptor and Use thereof
|
|
WO2023021113A1
(en)
|
2021-08-18 |
2023-02-23 |
Julius-Maximilians-Universität Würzburg |
Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
|
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
EP4456911A2
(en)
|
2021-12-31 |
2024-11-06 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
T cell therapy with vaccination as a combination immunotherapy against cancer
|
|
TW202340474A
(zh)
|
2022-01-11 |
2023-10-16 |
大陸商深圳市珈鈺生物科技有限公司 |
樹突細胞腫瘤疫苗和其用途
|
|
CN118256444A
(zh)
*
|
2022-04-26 |
2024-06-28 |
深圳市体内生物医药科技有限公司 |
一种嵌合抗原受体t细胞及其制备方法和应用
|
|
KR20250023497A
(ko)
|
2022-06-10 |
2025-02-18 |
리서치 디벨럽먼트 파운데이션 |
조작된 fcriib 선택적 igg1 fc 변이체 및 이의 용도
|
|
CN118359729A
(zh)
*
|
2023-01-19 |
2024-07-19 |
武汉昭智生物技术有限公司 |
一种car分子、包含其的细胞或外泌体及它们的应用
|
|
WO2025014896A1
(en)
|
2023-07-07 |
2025-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Humanized 40h3 antibody
|
|
WO2025160480A1
(en)
|
2024-01-26 |
2025-07-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Enhanced tumor reactivity of t cells lacking sit1, lax1, or trat1
|
|
WO2025250587A1
(en)
|
2024-05-29 |
2025-12-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Drug-regulatable, inducible cytokine expression
|