JP2014534196A5 - - Google Patents
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- Publication number
- JP2014534196A5 JP2014534196A5 JP2014535789A JP2014535789A JP2014534196A5 JP 2014534196 A5 JP2014534196 A5 JP 2014534196A5 JP 2014535789 A JP2014535789 A JP 2014535789A JP 2014535789 A JP2014535789 A JP 2014535789A JP 2014534196 A5 JP2014534196 A5 JP 2014534196A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- rasagiline
- weight
- amount
- propargyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PETXFKWYHQOVRD-CYBMUJFWSA-N C#CCN([C@H]1c2ccccc2CC1)C=O Chemical compound C#CCN([C@H]1c2ccccc2CC1)C=O PETXFKWYHQOVRD-CYBMUJFWSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161545422P | 2011-10-10 | 2011-10-10 | |
| US61/545,422 | 2011-10-10 | ||
| PCT/US2012/059356 WO2013055687A2 (en) | 2011-10-10 | 2012-10-09 | R(+)-n-formyl-propargyl-aminoindan |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014534196A JP2014534196A (ja) | 2014-12-18 |
| JP2014534196A5 true JP2014534196A5 (https=) | 2015-12-03 |
Family
ID=48042235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014535789A Pending JP2014534196A (ja) | 2011-10-10 | 2012-10-09 | Ｒ（＋）−ｎ−ホルミル−プロパルギル−アミノインダン |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9346746B2 (https=) |
| EP (1) | EP2766002A4 (https=) |
| JP (1) | JP2014534196A (https=) |
| KR (1) | KR20140090996A (https=) |
| CN (1) | CN103874487A (https=) |
| AR (1) | AR088297A1 (https=) |
| AU (1) | AU2012323349A1 (https=) |
| BR (1) | BR112014008555A2 (https=) |
| CA (1) | CA2851276A1 (https=) |
| EA (1) | EA201490761A1 (https=) |
| HK (1) | HK1200315A1 (https=) |
| IL (1) | IL231721A0 (https=) |
| MX (1) | MX2014004308A (https=) |
| WO (1) | WO2013055687A2 (https=) |
| ZA (1) | ZA201403043B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5701485B2 (ja) * | 2006-02-21 | 2015-04-15 | テバ ファーマシューティカル インダストリーズ リミティド | 多系統萎縮症の治療のためのラサギリンの使用 |
| CA2646250A1 (en) * | 2006-04-03 | 2007-10-18 | Teva Pharmaceutical Industries Ltd. | Use of rasagiline for the treatment of restless legs syndrome |
| ZA200903903B (en) * | 2006-12-14 | 2010-08-25 | Teva Pharma | Crystalline solid rasagiline base |
| US20090181086A1 (en) * | 2008-01-11 | 2009-07-16 | Muhammad Safadi | Rasagiline formulations, their preparation and use |
| WO2009151594A1 (en) * | 2008-06-10 | 2009-12-17 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| SI2451771T1 (sl) | 2009-07-09 | 2014-10-30 | Ratiopharm Gmbh | Soli rasagilina in njihovi farmacevtski pripravki |
| JP2013507352A (ja) * | 2009-10-09 | 2013-03-04 | テバ ファーマシューティカル インダストリーズ リミティド | 進行性核上性麻痺の治療のためのラサギリンの使用 |
| AU2010341499A1 (en) * | 2009-12-22 | 2012-08-09 | Teva Pharmaceutical Industries Ltd. | 3-keto-N-propargyl-1-aminoindan |
| AU2011282716A1 (en) | 2010-07-27 | 2013-03-14 | Teva Pharmaceutical Industries Ltd. | Dispersions of rasagiline citrate |
| JP2014534197A (ja) | 2011-10-10 | 2014-12-18 | テバ ファーマシューティカル インダストリーズ リミティド | Ｒ（＋）−ｎ−メチル−プロパルギルアミノインダン |
| US9308182B2 (en) | 2012-08-17 | 2016-04-12 | Teva Pharmaceutical Industries, Ltd. | Parenteral formulations of rasagiline |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3201470A (en) * | 1965-08-17 | Chsx c cech | ||
| IL92952A (en) | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
| US5744500A (en) | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
| IL99759A (en) | 1991-10-16 | 1997-06-10 | Teva Pharma | Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them |
| IL111240A (en) * | 1993-10-18 | 2001-10-31 | Teva Pharma | Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them |
| US5914349A (en) * | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
| DE69535315T2 (de) * | 1994-01-10 | 2007-06-28 | Teva Pharmaceutical Industries Ltd. | 1-aminoindanderivate und zusammensetzungen hiervon |
| IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
| IL118836A (en) | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
| DE69738275T2 (de) | 1996-12-18 | 2008-08-28 | Teva Pharmaceutical Industries Ltd. | Aminoindanderivate |
| IL149308A0 (en) * | 1999-10-27 | 2002-11-10 | Teva Pharma | Use of 1-aminoindan derivatives for treatment of manic disorders |
| SI1567152T1 (sl) | 2002-11-15 | 2013-10-30 | Teva Pharmaceutical Industries Ltd. | Uporaba rasagilina z riluzolom za zdravljenje amiotrofične lateralne skleroze |
| US7619077B2 (en) | 2003-02-06 | 2009-11-17 | University Of Georgia Research Foundation | Nucleic acids encoding a galacturonosyl tranferase enzyme (GALAT1) from arabidopsis |
| WO2006014973A2 (en) | 2004-07-26 | 2006-02-09 | Teva Pharmaceutical Industries, Ltd. | Pharmaceutical dosage forms including rasagiline |
| US20090111892A1 (en) | 2004-11-24 | 2009-04-30 | Shulamit Patashnik | Rasagiline Orally Disintegrating Compositions |
| CA2901244A1 (en) | 2005-02-23 | 2006-08-31 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations of improved content uniformity |
| EP1954667B1 (en) | 2005-11-17 | 2017-02-08 | Teva Pharmaceutical Industries Ltd | Methods for isolating propargylated aminoindans |
| US7572834B1 (en) | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
| JP5701485B2 (ja) | 2006-02-21 | 2015-04-15 | テバ ファーマシューティカル インダストリーズ リミティド | 多系統萎縮症の治療のためのラサギリンの使用 |
| CA2646250A1 (en) | 2006-04-03 | 2007-10-18 | Teva Pharmaceutical Industries Ltd. | Use of rasagiline for the treatment of restless legs syndrome |
| EP1892233A1 (de) | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
| JP5356248B2 (ja) | 2006-12-14 | 2013-12-04 | テバ ファーマシューティカル インダストリーズ リミティド | ラサギリンのタンニン酸塩 |
| ZA200903903B (en) | 2006-12-14 | 2010-08-25 | Teva Pharma | Crystalline solid rasagiline base |
| EP1987816A1 (de) | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
| AU2008296908B2 (en) | 2007-09-05 | 2014-01-09 | Teva Pharmaceutical Industries, Ltd. | Method of treating glaucoma using rasagiline |
| US8188149B2 (en) | 2007-09-17 | 2012-05-29 | Teva Pharmaceutical Industries, Ltd. | Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss |
| US20090181086A1 (en) | 2008-01-11 | 2009-07-16 | Muhammad Safadi | Rasagiline formulations, their preparation and use |
| WO2009151594A1 (en) | 2008-06-10 | 2009-12-17 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| JP2011522892A (ja) | 2008-06-13 | 2011-08-04 | テバ ファーマシューティカル インダストリーズ リミティド | パーキンソン病緩和のためのラサギリン |
| MX2010013875A (es) | 2008-06-19 | 2011-01-20 | Teva Pharma | Proceso para preparar y secar base de rasagilina solida. |
| AU2009260733B2 (en) | 2008-06-19 | 2015-01-29 | Teva Pharmaceutical Industries, Ltd. | Process for purifying rasagiline base |
| DE102008064061A1 (de) | 2008-12-19 | 2010-06-24 | Ratiopharm Gmbh | Feste Zusammensetzung mit dem Wirkstoff Rasagilin |
| US20100189790A1 (en) | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline formulation |
| SI2451771T1 (sl) | 2009-07-09 | 2014-10-30 | Ratiopharm Gmbh | Soli rasagilina in njihovi farmacevtski pripravki |
| JP2013507352A (ja) | 2009-10-09 | 2013-03-04 | テバ ファーマシューティカル インダストリーズ リミティド | 進行性核上性麻痺の治療のためのラサギリンの使用 |
| CN102048717B (zh) * | 2009-10-29 | 2014-02-19 | 重庆医药工业研究院有限责任公司 | 一种稳定的雷沙吉兰组合物 |
| AU2010341499A1 (en) | 2009-12-22 | 2012-08-09 | Teva Pharmaceutical Industries Ltd. | 3-keto-N-propargyl-1-aminoindan |
| CA2806740A1 (en) | 2010-07-27 | 2012-02-02 | Teva Pharmaceutical Industries Ltd. | Use of rasagiline for the treatment of olfactory dysfunction |
| AU2011282716A1 (en) | 2010-07-27 | 2013-03-14 | Teva Pharmaceutical Industries Ltd. | Dispersions of rasagiline citrate |
| US20120101168A1 (en) | 2010-10-26 | 2012-04-26 | Eliezer Bahar | Deuterium enriched rasagiline |
| JP2014534197A (ja) | 2011-10-10 | 2014-12-18 | テバ ファーマシューティカル インダストリーズ リミティド | Ｒ（＋）−ｎ−メチル−プロパルギルアミノインダン |
| CN103857389A (zh) | 2011-10-10 | 2014-06-11 | 泰华制药工业有限公司 | 雷沙吉兰柠檬酰胺 |
| US9308182B2 (en) | 2012-08-17 | 2016-04-12 | Teva Pharmaceutical Industries, Ltd. | Parenteral formulations of rasagiline |
-
2012
- 2012-10-09 WO PCT/US2012/059356 patent/WO2013055687A2/en not_active Ceased
- 2012-10-09 EA EA201490761A patent/EA201490761A1/ru unknown
- 2012-10-09 JP JP2014535789A patent/JP2014534196A/ja active Pending
- 2012-10-09 HK HK15100235.8A patent/HK1200315A1/xx unknown
- 2012-10-09 US US13/647,685 patent/US9346746B2/en not_active Expired - Fee Related
- 2012-10-09 KR KR1020147012454A patent/KR20140090996A/ko not_active Withdrawn
- 2012-10-09 CA CA2851276A patent/CA2851276A1/en not_active Abandoned
- 2012-10-09 EP EP12839776.7A patent/EP2766002A4/en not_active Withdrawn
- 2012-10-09 CN CN201280049741.8A patent/CN103874487A/zh active Pending
- 2012-10-09 AU AU2012323349A patent/AU2012323349A1/en not_active Abandoned
- 2012-10-09 BR BR112014008555A patent/BR112014008555A2/pt not_active IP Right Cessation
- 2012-10-09 MX MX2014004308A patent/MX2014004308A/es unknown
- 2012-10-10 AR ARP120103781A patent/AR088297A1/es unknown
-
2014
- 2014-03-26 IL IL231721A patent/IL231721A0/en unknown
- 2014-04-25 ZA ZA2014/03043A patent/ZA201403043B/en unknown
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