JP2014533282A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014533282A5 JP2014533282A5 JP2014541358A JP2014541358A JP2014533282A5 JP 2014533282 A5 JP2014533282 A5 JP 2014533282A5 JP 2014541358 A JP2014541358 A JP 2014541358A JP 2014541358 A JP2014541358 A JP 2014541358A JP 2014533282 A5 JP2014533282 A5 JP 2014533282A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- urea
- dioxoimidazolidin
- bromophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CNC*C(NCC(**)=O)=O Chemical compound CNC*C(NCC(**)=O)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558080P | 2011-11-10 | 2011-11-10 | |
| US61/558,080 | 2011-11-10 | ||
| PCT/US2012/064571 WO2013071203A1 (en) | 2011-11-10 | 2012-11-10 | 2,5-dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (fprl-1) receptor modulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017004062A Division JP6392382B2 (ja) | 2011-11-10 | 2017-01-13 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533282A JP2014533282A (ja) | 2014-12-11 |
| JP2014533282A5 true JP2014533282A5 (cg-RX-API-DMAC7.html) | 2017-01-05 |
| JP6078075B2 JP6078075B2 (ja) | 2017-02-08 |
Family
ID=47222328
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541358A Expired - Fee Related JP6078075B2 (ja) | 2011-11-10 | 2012-11-10 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
| JP2017004062A Expired - Fee Related JP6392382B2 (ja) | 2011-11-10 | 2017-01-13 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017004062A Expired - Fee Related JP6392382B2 (ja) | 2011-11-10 | 2017-01-13 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8492556B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3103797B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6078075B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102271500B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104114541A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2012335039C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014011316A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2855390C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3103797T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2733826T3 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2645673C2 (cg-RX-API-DMAC7.html) |
| TR (1) | TR201909663T4 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013071203A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX376348B (es) | 2011-10-26 | 2025-03-07 | Allergan Inc | Derivados de amida de aminoacidos sustituidos con n-urea como moduladores de receptor de tipo peptido receptor de formilo-1 (fprl-1). |
| US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| US9850264B2 (en) * | 2013-03-06 | 2017-12-26 | Allergan, Inc. | Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases |
| KR20210024691A (ko) | 2013-03-06 | 2021-03-05 | 알러간, 인코포레이티드 | 피부 질환 치료용 포르밀 펩티드 수용체 2의 항진제의 용도 |
| AR097279A1 (es) * | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| RU2703725C1 (ru) | 2013-11-21 | 2019-10-22 | Аллерган, Инк. | Производные фенилкарбамата в качестве модуляторов формилпептидного рецептора |
| PE20161206A1 (es) * | 2013-11-28 | 2016-11-05 | Kyorin Seiyaku Kk | Derivado de urea o sal farmacologicamente aceptable del mismo |
| WO2015116566A1 (en) | 2014-01-29 | 2015-08-06 | Allergan, Inc. | 2,5-dioxoimidazolidin-1-yl-3-urea derivatives as formyl peptide modulators |
| US9604934B2 (en) | 2014-01-29 | 2017-03-28 | Allergan, Inc. | Urea hydantoin derivatives as formyl peptide modulators |
| EP3145916B1 (en) * | 2014-05-21 | 2020-02-12 | Allergan, Inc. | Imidazole derivatives as formyl peptide receptor modulators |
| AU2015360291A1 (en) | 2014-12-11 | 2017-07-13 | President And Fellows Of Harvard College | Inhibitors of cellular necrosis and related methods |
| EA201792382A1 (ru) * | 2015-05-27 | 2018-04-30 | Киорин Фармасютикал Ко., Лтд. | Производное мочевины или его фармакологически приемлемая соль |
| US10858314B2 (en) | 2015-05-27 | 2020-12-08 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| JP2020015664A (ja) * | 2016-11-21 | 2020-01-30 | 宇部興産株式会社 | 含窒素多環式ヘテロ環誘導体 |
| WO2018227067A1 (en) * | 2017-06-09 | 2018-12-13 | Bristol-Myers Squibb Company | Cyclopropyl urea formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| MY204384A (en) * | 2018-03-05 | 2024-08-27 | Bristol Myers Squibb Co | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
| KR102217512B1 (ko) * | 2020-07-07 | 2021-02-19 | 한화시스템 주식회사 | 배터리 관리 시스템을 통한 회수 요청 또는 자동 복귀를 수행하는 무인 잠수정 |
| CN114805334B (zh) * | 2022-05-24 | 2023-06-09 | 深圳大学 | 一种QC和GSK-3β多靶向抑制剂及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3924531B2 (ja) * | 2000-05-31 | 2007-06-06 | 田辺製薬株式会社 | αＬβ２介在細胞接着阻害剤 |
| SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| WO2003006424A1 (en) * | 2001-07-10 | 2003-01-23 | 4Sc Ag | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| FR2850652B1 (fr) * | 2003-01-31 | 2008-05-30 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
| CN1894580A (zh) * | 2003-11-07 | 2007-01-10 | 阿卡蒂亚药品公司 | 脂氧素受体fprl1作为一种用于鉴定能有效治疗疼痛和炎症化合物的工具 |
| US20090253908A1 (en) * | 2004-03-11 | 2009-10-08 | Glaxo Group Limited | Novel m3 muscarinic acetylchoine receptor antagonists |
| CN100506802C (zh) * | 2004-06-04 | 2009-07-01 | 中国科学院上海药物研究所 | 一类甲酰肽样受体-1调节剂、其制备方法和用途 |
| US20080004282A1 (en) * | 2006-04-10 | 2008-01-03 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| JP2011503182A (ja) * | 2007-11-15 | 2011-01-27 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 使用方法 |
| US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| US8541577B2 (en) * | 2011-11-10 | 2013-09-24 | Allergan, Inc. | Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators |
| EP2814815A1 (en) * | 2012-02-16 | 2014-12-24 | Allergan, Inc. | Imidazolidine-2,4-dione derivatives as n-formyl peptide receptor 2 modulators |
-
2012
- 2012-11-09 US US13/673,800 patent/US8492556B2/en active Active
- 2012-11-10 ES ES16177209T patent/ES2733826T3/es active Active
- 2012-11-10 CN CN201280060036.8A patent/CN104114541A/zh active Pending
- 2012-11-10 EP EP16177209.0A patent/EP3103797B1/en active Active
- 2012-11-10 BR BR112014011316A patent/BR112014011316A2/pt not_active Application Discontinuation
- 2012-11-10 CA CA2855390A patent/CA2855390C/en active Active
- 2012-11-10 KR KR1020147015539A patent/KR102271500B1/ko active Active
- 2012-11-10 DK DK16177209.0T patent/DK3103797T3/da active
- 2012-11-10 TR TR2019/09663T patent/TR201909663T4/tr unknown
- 2012-11-10 JP JP2014541358A patent/JP6078075B2/ja not_active Expired - Fee Related
- 2012-11-10 WO PCT/US2012/064571 patent/WO2013071203A1/en not_active Ceased
- 2012-11-10 AU AU2012335039A patent/AU2012335039C1/en not_active Ceased
- 2012-11-10 EP EP12791050.3A patent/EP2776403B1/en not_active Not-in-force
- 2012-11-10 RU RU2014122753A patent/RU2645673C2/ru active
-
2017
- 2017-01-13 JP JP2017004062A patent/JP6392382B2/ja not_active Expired - Fee Related
- 2017-11-16 AU AU2017261559A patent/AU2017261559C1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014533282A5 (cg-RX-API-DMAC7.html) | ||
| RU2014122753A (ru) | Производные 2,5-диоксоимидазолидин-1-ил-3-фенилмочевины в качестве модуляторов формилпептидного рецептора 1 (fprl-1) | |
| JP2016512194A5 (cg-RX-API-DMAC7.html) | ||
| RU2424233C2 (ru) | Производные бензимидазола, методы их получения, применение их в качестве агонистов фарнезоид-х-рецептора (fxr) и содержащие их фармацевтические препараты | |
| Gaba et al. | Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions | |
| JP2012525431A5 (cg-RX-API-DMAC7.html) | ||
| ME00044B (me) | Substituisani imidazoli i njihova upotreba kao pesticida | |
| RU2015136774A (ru) | Применение агонистов формилпептидного рецептора 2 для лечения воспалительных заболеваний глаз | |
| RU2015106787A (ru) | Замещенные пирролы, активные в качестве ингибиторов киназ | |
| RU2005111225A (ru) | Производные триазаспиро[5.5]ундекана и лекарственные средства, содержащие их в качестве активного ингредиента | |
| RU2011121665A (ru) | Производные 7-гидроксибензимидазол-4-илметанона и содержащие их ингибиторы рвк | |
| JP2014516360A5 (cg-RX-API-DMAC7.html) | ||
| KR20080080410A (ko) | 이미다졸린 유도체의 치환된 2-이미다졸의 용도 | |
| FI3625233T5 (fi) | 3-(((((2s,5r)-2-karbamoyyli-7-okso-1,6-diatsabisyklo[3.2.1]oktan-6-yyli)oksi)sulfonyyli)oksi)-2,2-dimetyylipropanoaattijohdannaisia ja niihin liittyviä yhdisteitä beetalaktamaasiestäjien suun kautta otettavina aihiolääkkeinä bakteeri-infektioiden hoitamiseksi | |
| JP2013507425A5 (cg-RX-API-DMAC7.html) | ||
| RU2013151174A (ru) | Замещенные пиримидинилпирролы, активные в качестве ингибиторов киназы | |
| RU2014111980A (ru) | Сшиваемая композиция, способная к сшиванию по реакции присоединения михаэля (rma) | |
| EA031030B1 (ru) | Ингибиторы фактора в комплемента на основе производных пиперидинилиндола и их применение | |
| JP2012507525A5 (cg-RX-API-DMAC7.html) | ||
| RU2389722C2 (ru) | Варианты имидазола в качестве модуляторов рецептора гамма-аминомасляной кислоты (gaba) для лечения желудочно-кишечных (жк) расстройств | |
| EP1261601A1 (de) | Substituierte indole zur modulierung von nfkb-aktivität | |
| RU2503663C2 (ru) | Мостиковые шестичленные циклические соединения | |
| JP2010539151A5 (cg-RX-API-DMAC7.html) | ||
| JP2015535834A5 (cg-RX-API-DMAC7.html) | ||
| WO2012109491A1 (en) | Methods and compositions for improving cognitive function |