JP2014523444A - 癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 - Google Patents

癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 Download PDF

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JP2014523444A
JP2014523444A JP2014521722A JP2014521722A JP2014523444A JP 2014523444 A JP2014523444 A JP 2014523444A JP 2014521722 A JP2014521722 A JP 2014521722A JP 2014521722 A JP2014521722 A JP 2014521722A JP 2014523444 A JP2014523444 A JP 2014523444A
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nanocarrier
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リーマ ゼイネルデン,
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UNM Rainforest Innovations
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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/908Mechanical repair performed/surgical
    • Y10S977/911Cancer cell destruction

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JP2014521722A 2011-07-19 2012-07-18 癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 Pending JP2014523444A (ja)

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US201161509251P 2011-07-19 2011-07-19
US61/509,251 2011-07-19
PCT/US2012/047133 WO2013012891A1 (en) 2011-07-19 2012-07-18 Intraperitoneally-administered nanocarriers that release their therapeutic load based on the inflammatory environment of cancers

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JP2014523444A true JP2014523444A (ja) 2014-09-11
JP2014523444A5 JP2014523444A5 (enExample) 2015-09-10

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US (1) US9532949B2 (enExample)
EP (1) EP2734191A4 (enExample)
JP (1) JP2014523444A (enExample)
CN (1) CN103917224A (enExample)
AU (1) AU2012284147A1 (enExample)
BR (1) BR112014001346A8 (enExample)
CA (1) CA2842306A1 (enExample)
EA (1) EA201490302A1 (enExample)
WO (1) WO2013012891A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018016645A1 (ja) * 2016-07-22 2018-01-25 国立大学法人秋田大学 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発
JP2018505224A (ja) * 2015-02-13 2018-02-22 オーピーナノ シーオー エルティーディーOP Nano Co.,Ltd. ナノ粒子を含む組成物並びに腫瘍を治療する方法
JP2019531342A (ja) * 2016-09-13 2019-10-31 ラスナ・リサーチ・インコーポレイテッド ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9993437B2 (en) 2007-12-06 2018-06-12 The Regents Of The University Of California Mesoporous silica nanoparticles for biomedical applications
KR101495951B1 (ko) 2009-03-30 2015-02-25 에자이 알앤드디 매니지먼트 가부시키가이샤 리포솜 조성물
US8992984B1 (en) 2009-10-21 2015-03-31 Stc.Unm Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
US20120207795A1 (en) 2010-07-13 2012-08-16 The Regents Of The University Of California Cationic polymer coated mesoporous silica nanoparticles and uses thereof
CN103687590A (zh) 2011-04-28 2014-03-26 Stc·Unm公司 用于靶向给药的多孔纳米颗粒支撑脂双层(原始细胞)及其使用方法
US10220004B2 (en) 2011-07-14 2019-03-05 The Regents Of The University Of California Method of controlled delivery using sub-micron-scale machines
BR112014001346A8 (pt) 2011-07-19 2018-05-08 Stc Unm composto nanotransportador, método, composto farmacêutico e uso de um composto
US9687569B2 (en) 2012-08-16 2017-06-27 University Of Washington Through Its Center For Commercialization Theranostic nanoparticle and methods for making and using the nanoparticle
EP2964201B1 (en) * 2013-03-05 2024-02-14 The Regents of the University of California Lipid bilayer coated mesoporous silica nanoparticles with a high loading capacity for one or more anticancer agents
CN103611172B (zh) * 2013-12-02 2015-06-03 东南大学 载纳米雄黄磁性白蛋白纳米球及制备方法
CN103919803B (zh) * 2014-04-16 2018-07-31 厦门大学 一种装载砷剂的抗癌纳米药物及其制备方法
US10500164B2 (en) 2014-09-19 2019-12-10 The American University In Cairo Nanoparticle-based combinatorial therapy
WO2016141161A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Dual loaded liposomal pharmaceutical formulations
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
CA3001699A1 (en) * 2015-10-15 2017-04-20 Lipomedix Pharmaceuticals Ltd. Liposome composition co-encapsulating doxorubicin and a prodrug of mitomycin c
US20180369422A1 (en) * 2015-12-31 2018-12-27 City Of Hope Nanoparticles for cancer detection
EP4218739A3 (en) 2016-01-08 2023-08-09 The Regents of The University of California Mesoporous silica nanoparticles with lipid bilayer coating for cargo delivery
WO2017120504A1 (en) 2016-01-08 2017-07-13 Durfee Paul N Osteotropic nanoparticles for prevention or treatment of bone metastases
EP3449921B1 (en) * 2016-04-28 2023-05-31 Eisai R&D Management Co., Ltd. Eribulin for inhibiting tumor growth
CN107362142B (zh) * 2016-05-13 2023-04-25 山东新时代药业有限公司 一种氟维司群脂质体注射液及其制备方法
CN106943378B (zh) * 2017-02-16 2020-09-15 上海交通大学 红细胞膜包封聚酯类载三氧化二砷纳米粒及其制备方法
WO2018160865A1 (en) 2017-03-01 2018-09-07 Charles Jeffrey Brinker Active targeting of cells by monosized protocells
CN107096037B (zh) * 2017-04-11 2019-12-31 同济大学 一种酶促小分子自组装制备纳米凝胶的方法
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US12383499B2 (en) 2018-01-01 2025-08-12 The Regents Of The University Of California Scale up synthesis of silicasome nanocarriers
WO2019213270A1 (en) * 2018-05-01 2019-11-07 Rutgers, The State University Of New Jersey Benzalkonium-embedded mesostructured silica compositions and uses of same
WO2020068798A1 (en) 2018-09-24 2020-04-02 Guo Jimin Living mammalian cells modified with functional modular nanoparticles
SG11202104580PA (en) * 2018-11-02 2021-05-28 Tesorx Pharma Llc Liposomal enhanced intra-peritoneal chemotherapy
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US12208164B2 (en) 2019-02-28 2025-01-28 Unm Rainforest Innovations Modular metal-organic polyhedra superassembly compositions
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US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN110448541B (zh) * 2019-08-02 2021-10-01 中山大学 双功能化纳米粒、可溶性微针及其制备方法与应用
CN114686416B (zh) * 2020-12-30 2024-03-19 湖南大学 一种膜融合脂质体及其应用
US11779652B2 (en) 2021-06-18 2023-10-10 Imam Abdulrahman Bin Faisal University Porous silicate/magnetic ferrite nanocarrier for combination anti-cancer therapeutic and antioxidant delivery
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CN115105584B (zh) * 2022-06-28 2023-03-31 长春生物制品研究所有限责任公司 一种卡式瓶多剂量笔式注射组合包装的干扰素注射液

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502261A (ja) * 1991-09-09 1995-03-09 トンプソン デビッド エイチ 光活性化可能なトリガーされた放出を伴なうリポソーマル送達システム
US20080279764A1 (en) * 2007-03-09 2008-11-13 Anthony Manganaro Method and composition for treating cancer
JP2010500340A (ja) * 2006-08-11 2010-01-07 パナセア バイオテック リミテッド 活性成分を送達するための粒子、その製造方法、および組成物
WO2010078569A2 (en) * 2009-01-05 2010-07-08 Stc.Unm Porous nanoparticle supported lipid bilayer nanostructures
JP2011500520A (ja) * 2007-10-12 2011-01-06 ノヴォソム アクチェンゲゼルシャフト 中性脂質を含有する両性リポソームの改良または該両性リポソームに関連する改良

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022468A1 (en) * 1993-04-02 1994-10-13 Anticancer, Inc. Method for delivering beneficial compositions to hair follicles
US5820879A (en) * 1993-02-12 1998-10-13 Access Pharmaceuticals, Inc. Method of delivering a lipid-coated condensed-phase microparticle composition
US20020039594A1 (en) * 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same
US6264741B1 (en) 1998-11-25 2001-07-24 Sandia Corporation Self-assembly of nanocomposite materials
US6350464B1 (en) * 1999-01-11 2002-02-26 Guilford Pharmaceuticals, Inc. Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
WO2003016040A1 (en) 2001-04-16 2003-02-27 The Regents Of The University Of California Membrane mimetic architectures on nanoporous materials
WO2003055469A1 (en) 2001-12-21 2003-07-10 Celator Technologies Inc. Improved polymer-lipid delivery vehicles
US20040005352A1 (en) 2002-04-16 2004-01-08 Lopez Gabriel P. Biologically functionalized porous microspheres
US20040101822A1 (en) 2002-11-26 2004-05-27 Ulrich Wiesner Fluorescent silica-based nanoparticles
US7563451B2 (en) 2003-07-22 2009-07-21 Iowa State University Research Foundation, Inc. Capped mesoporous silicates
US20070037751A1 (en) * 2003-08-06 2007-02-15 Gastrotech Pharma A/S Uses of secretagogues like ghrelin in cancer cachexia and for stimulating appetite
JP5557127B2 (ja) 2005-02-14 2014-07-23 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 層状ナノ粒子
US7514267B1 (en) 2005-08-19 2009-04-07 Stcunm Detection systems utilizing supported lipid bilayers
US20080160313A1 (en) 2006-04-26 2008-07-03 Gabriel Lopez Lipid bilayers on nanotextured solid surfaces
US20080213377A1 (en) 2006-12-08 2008-09-04 Bhatia Sangeeta N Delivery of Nanoparticles and/or Agents to Cells
US9993437B2 (en) 2007-12-06 2018-06-12 The Regents Of The University Of California Mesoporous silica nanoparticles for biomedical applications
US20110105995A1 (en) * 2008-01-16 2011-05-05 Zhu Ting F Uniform-sized, multi-drug carrying, and photosensitive liposomes for advanced drug delivery
US8962344B2 (en) 2008-03-16 2015-02-24 Synamem Corporation Membrane-coated particles
MX2010011680A (es) 2008-04-25 2011-05-03 Univ Northwestern Nanoestructuras adecuadas para secuestrar colesterol y otras moleculas.
JP5366612B2 (ja) 2008-05-20 2013-12-11 株式会社東芝 画像処理装置、画像処理方法および画像処理プログラム
CN101658533A (zh) 2008-08-29 2010-03-03 首都医科大学宣武医院 抗肿瘤药物的干细胞递送
US8992984B1 (en) 2009-10-21 2015-03-31 Stc.Unm Protocells and their use for targeted delivery of multicomponent cargos to cancer cells
US20130017210A1 (en) 2010-03-17 2013-01-17 Stc.Unm Display of antibody fragments on virus-like particles of rna bacteriophages
US20110300186A1 (en) 2010-04-14 2011-12-08 Battelle Memorial Institute Functionalized Nano- and Micro-materials for Medical Therapies
CN103687590A (zh) 2011-04-28 2014-03-26 Stc·Unm公司 用于靶向给药的多孔纳米颗粒支撑脂双层(原始细胞)及其使用方法
BR112014001346A8 (pt) 2011-07-19 2018-05-08 Stc Unm composto nanotransportador, método, composto farmacêutico e uso de um composto
US20150272885A1 (en) 2011-10-14 2015-10-01 Stc.Unm Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery including transdermal delivery of cargo and methods thereof
WO2013103614A1 (en) 2011-12-30 2013-07-11 Stc.Unm Crlf-2 binding peptides, protocells and viral-like particles useful in the treatment of cancer, including acute lymphoblastic leukemia (all)
EP2981249A4 (en) 2013-04-02 2016-11-23 Stc Unm MESOPOROUS ALAN NANOPARTICLES AS A UNIVERSAL PLATFORM FOR ADSORPTION, PRESENTATION, AND ADMINISTRATION OF ANTIGENS
EP2981611A4 (en) 2013-04-02 2016-11-16 Stc Unm ANTIBIOTICUM PROTOCOLS AND PHARMACEUTICAL FORMULATIONS AND TREATMENT METHODS THEREWITH
US9855217B2 (en) 2013-09-18 2018-01-02 Stc. Unm Toroidal mesoporous silica nanoparticles (TMSNPs) and related protocells
WO2015042268A1 (en) 2013-09-18 2015-03-26 Stc.Unm Core and surface modification of mesoporous silica nanoparticles to achieve cell specific targeting in vivo

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07502261A (ja) * 1991-09-09 1995-03-09 トンプソン デビッド エイチ 光活性化可能なトリガーされた放出を伴なうリポソーマル送達システム
JP2010500340A (ja) * 2006-08-11 2010-01-07 パナセア バイオテック リミテッド 活性成分を送達するための粒子、その製造方法、および組成物
US20080279764A1 (en) * 2007-03-09 2008-11-13 Anthony Manganaro Method and composition for treating cancer
JP2011500520A (ja) * 2007-10-12 2011-01-06 ノヴォソム アクチェンゲゼルシャフト 中性脂質を含有する両性リポソームの改良または該両性リポソームに関連する改良
WO2010078569A2 (en) * 2009-01-05 2010-07-08 Stc.Unm Porous nanoparticle supported lipid bilayer nanostructures

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J. AM. CHEM. SOC., vol. 131, JPN6016016419, 2009, pages 7567 - 7569, ISSN: 0003308874 *
NAT. MATER., vol. 10, JPN6016016420, April 2011 (2011-04-01), pages 389 - 397, ISSN: 0003308875 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018505224A (ja) * 2015-02-13 2018-02-22 オーピーナノ シーオー エルティーディーOP Nano Co.,Ltd. ナノ粒子を含む組成物並びに腫瘍を治療する方法
WO2018016645A1 (ja) * 2016-07-22 2018-01-25 国立大学法人秋田大学 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発
JPWO2018016645A1 (ja) * 2016-07-22 2019-06-13 国立大学法人秋田大学 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発
JP2022118008A (ja) * 2016-07-22 2022-08-12 株式会社リピドームラボ 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発
JP2019531342A (ja) * 2016-09-13 2019-10-31 ラスナ・リサーチ・インコーポレイテッド ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法
JP7032406B2 (ja) 2016-09-13 2022-03-08 ラスナ・リサーチ・インコーポレイテッド ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法

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EP2734191A1 (en) 2014-05-28
US9532949B2 (en) 2017-01-03
US20140212479A1 (en) 2014-07-31
BR112014001346A2 (pt) 2017-07-18
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AU2012284147A1 (en) 2014-02-27
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