JP2014523444A - 癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 - Google Patents
癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 Download PDFInfo
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- JP2014523444A JP2014523444A JP2014521722A JP2014521722A JP2014523444A JP 2014523444 A JP2014523444 A JP 2014523444A JP 2014521722 A JP2014521722 A JP 2014521722A JP 2014521722 A JP2014521722 A JP 2014521722A JP 2014523444 A JP2014523444 A JP 2014523444A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/908—Mechanical repair performed/surgical
- Y10S977/911—Cancer cell destruction
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161509251P | 2011-07-19 | 2011-07-19 | |
| US61/509,251 | 2011-07-19 | ||
| PCT/US2012/047133 WO2013012891A1 (en) | 2011-07-19 | 2012-07-18 | Intraperitoneally-administered nanocarriers that release their therapeutic load based on the inflammatory environment of cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014523444A true JP2014523444A (ja) | 2014-09-11 |
| JP2014523444A5 JP2014523444A5 (enExample) | 2015-09-10 |
Family
ID=47558435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014521722A Pending JP2014523444A (ja) | 2011-07-19 | 2012-07-18 | 癌の炎症性環境に基づいて治療用積載物を放出する、腹腔内投与されるナノ担体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9532949B2 (enExample) |
| EP (1) | EP2734191A4 (enExample) |
| JP (1) | JP2014523444A (enExample) |
| CN (1) | CN103917224A (enExample) |
| AU (1) | AU2012284147A1 (enExample) |
| BR (1) | BR112014001346A8 (enExample) |
| CA (1) | CA2842306A1 (enExample) |
| EA (1) | EA201490302A1 (enExample) |
| WO (1) | WO2013012891A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018016645A1 (ja) * | 2016-07-22 | 2018-01-25 | 国立大学法人秋田大学 | 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発 |
| JP2018505224A (ja) * | 2015-02-13 | 2018-02-22 | オーピーナノ シーオー エルティーディーOP Nano Co.,Ltd. | ナノ粒子を含む組成物並びに腫瘍を治療する方法 |
| JP2019531342A (ja) * | 2016-09-13 | 2019-10-31 | ラスナ・リサーチ・インコーポレイテッド | ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US9993437B2 (en) | 2007-12-06 | 2018-06-12 | The Regents Of The University Of California | Mesoporous silica nanoparticles for biomedical applications |
| KR101495951B1 (ko) | 2009-03-30 | 2015-02-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 리포솜 조성물 |
| US8992984B1 (en) | 2009-10-21 | 2015-03-31 | Stc.Unm | Protocells and their use for targeted delivery of multicomponent cargos to cancer cells |
| US20120207795A1 (en) | 2010-07-13 | 2012-08-16 | The Regents Of The University Of California | Cationic polymer coated mesoporous silica nanoparticles and uses thereof |
| CN103687590A (zh) | 2011-04-28 | 2014-03-26 | Stc·Unm公司 | 用于靶向给药的多孔纳米颗粒支撑脂双层(原始细胞)及其使用方法 |
| US10220004B2 (en) | 2011-07-14 | 2019-03-05 | The Regents Of The University Of California | Method of controlled delivery using sub-micron-scale machines |
| BR112014001346A8 (pt) | 2011-07-19 | 2018-05-08 | Stc Unm | composto nanotransportador, método, composto farmacêutico e uso de um composto |
| US9687569B2 (en) | 2012-08-16 | 2017-06-27 | University Of Washington Through Its Center For Commercialization | Theranostic nanoparticle and methods for making and using the nanoparticle |
| EP2964201B1 (en) * | 2013-03-05 | 2024-02-14 | The Regents of the University of California | Lipid bilayer coated mesoporous silica nanoparticles with a high loading capacity for one or more anticancer agents |
| CN103611172B (zh) * | 2013-12-02 | 2015-06-03 | 东南大学 | 载纳米雄黄磁性白蛋白纳米球及制备方法 |
| CN103919803B (zh) * | 2014-04-16 | 2018-07-31 | 厦门大学 | 一种装载砷剂的抗癌纳米药物及其制备方法 |
| US10500164B2 (en) | 2014-09-19 | 2019-12-10 | The American University In Cairo | Nanoparticle-based combinatorial therapy |
| WO2016141161A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
| WO2016141167A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
| CA3001699A1 (en) * | 2015-10-15 | 2017-04-20 | Lipomedix Pharmaceuticals Ltd. | Liposome composition co-encapsulating doxorubicin and a prodrug of mitomycin c |
| US20180369422A1 (en) * | 2015-12-31 | 2018-12-27 | City Of Hope | Nanoparticles for cancer detection |
| EP4218739A3 (en) | 2016-01-08 | 2023-08-09 | The Regents of The University of California | Mesoporous silica nanoparticles with lipid bilayer coating for cargo delivery |
| WO2017120504A1 (en) | 2016-01-08 | 2017-07-13 | Durfee Paul N | Osteotropic nanoparticles for prevention or treatment of bone metastases |
| EP3449921B1 (en) * | 2016-04-28 | 2023-05-31 | Eisai R&D Management Co., Ltd. | Eribulin for inhibiting tumor growth |
| CN107362142B (zh) * | 2016-05-13 | 2023-04-25 | 山东新时代药业有限公司 | 一种氟维司群脂质体注射液及其制备方法 |
| CN106943378B (zh) * | 2017-02-16 | 2020-09-15 | 上海交通大学 | 红细胞膜包封聚酯类载三氧化二砷纳米粒及其制备方法 |
| WO2018160865A1 (en) | 2017-03-01 | 2018-09-07 | Charles Jeffrey Brinker | Active targeting of cells by monosized protocells |
| CN107096037B (zh) * | 2017-04-11 | 2019-12-31 | 同济大学 | 一种酶促小分子自组装制备纳米凝胶的方法 |
| CN107213479B (zh) * | 2017-06-22 | 2018-12-28 | 苏州杰纳生物科技有限公司 | 一种包含过氧化氢酶的组合物及用途 |
| CN108014094A (zh) * | 2017-12-26 | 2018-05-11 | 厦门大学 | 一种含顺铂和砷剂的纳米药物及其制备方法 |
| US12383499B2 (en) | 2018-01-01 | 2025-08-12 | The Regents Of The University Of California | Scale up synthesis of silicasome nanocarriers |
| WO2019213270A1 (en) * | 2018-05-01 | 2019-11-07 | Rutgers, The State University Of New Jersey | Benzalkonium-embedded mesostructured silica compositions and uses of same |
| WO2020068798A1 (en) | 2018-09-24 | 2020-04-02 | Guo Jimin | Living mammalian cells modified with functional modular nanoparticles |
| SG11202104580PA (en) * | 2018-11-02 | 2021-05-28 | Tesorx Pharma Llc | Liposomal enhanced intra-peritoneal chemotherapy |
| TR201820952A2 (tr) * | 2018-12-28 | 2020-07-21 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Granülosi̇t koloni̇ uyarici faktör i̇çeren bi̇r kombi̇nasyon |
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-
2012
- 2012-07-18 BR BR112014001346A patent/BR112014001346A8/pt not_active IP Right Cessation
- 2012-07-18 EP EP12815024.0A patent/EP2734191A4/en not_active Withdrawn
- 2012-07-18 US US14/233,527 patent/US9532949B2/en not_active Expired - Fee Related
- 2012-07-18 JP JP2014521722A patent/JP2014523444A/ja active Pending
- 2012-07-18 CN CN201280045672.3A patent/CN103917224A/zh active Pending
- 2012-07-18 CA CA2842306A patent/CA2842306A1/en not_active Abandoned
- 2012-07-18 EA EA201490302A patent/EA201490302A1/ru unknown
- 2012-07-18 WO PCT/US2012/047133 patent/WO2013012891A1/en not_active Ceased
- 2012-07-18 AU AU2012284147A patent/AU2012284147A1/en not_active Abandoned
Patent Citations (5)
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Cited By (6)
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| JP2018505224A (ja) * | 2015-02-13 | 2018-02-22 | オーピーナノ シーオー エルティーディーOP Nano Co.,Ltd. | ナノ粒子を含む組成物並びに腫瘍を治療する方法 |
| WO2018016645A1 (ja) * | 2016-07-22 | 2018-01-25 | 国立大学法人秋田大学 | 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発 |
| JPWO2018016645A1 (ja) * | 2016-07-22 | 2019-06-13 | 国立大学法人秋田大学 | 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発 |
| JP2022118008A (ja) * | 2016-07-22 | 2022-08-12 | 株式会社リピドームラボ | 新規リン脂質およびその利用ならびにリン脂質分離測定法の開発 |
| JP2019531342A (ja) * | 2016-09-13 | 2019-10-31 | ラスナ・リサーチ・インコーポレイテッド | ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法 |
| JP7032406B2 (ja) | 2016-09-13 | 2022-03-08 | ラスナ・リサーチ・インコーポレイテッド | ダクチノマイシン組成物並びに骨髄異形成症候群及び急性骨髄性白血病の治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2842306A1 (en) | 2013-01-24 |
| WO2013012891A1 (en) | 2013-01-24 |
| EA201490302A1 (ru) | 2014-07-30 |
| CN103917224A (zh) | 2014-07-09 |
| EP2734191A1 (en) | 2014-05-28 |
| US9532949B2 (en) | 2017-01-03 |
| US20140212479A1 (en) | 2014-07-31 |
| BR112014001346A2 (pt) | 2017-07-18 |
| BR112014001346A8 (pt) | 2018-05-08 |
| AU2012284147A1 (en) | 2014-02-27 |
| EP2734191A4 (en) | 2015-04-29 |
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