JP2014521735A5 - - Google Patents

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Publication number
JP2014521735A5
JP2014521735A5 JP2014525437A JP2014525437A JP2014521735A5 JP 2014521735 A5 JP2014521735 A5 JP 2014521735A5 JP 2014525437 A JP2014525437 A JP 2014525437A JP 2014525437 A JP2014525437 A JP 2014525437A JP 2014521735 A5 JP2014521735 A5 JP 2014521735A5
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JP
Japan
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compound
pharmaceutically acceptable
acceptable salt
condition
disease
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JP2014525437A
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Japanese (ja)
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JP2014521735A (ja
JP6059723B2 (ja
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Priority claimed from GBGB1114103.3A external-priority patent/GB201114103D0/en
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Publication of JP2014521735A5 publication Critical patent/JP2014521735A5/ja
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Publication of JP6059723B2 publication Critical patent/JP6059723B2/ja
Expired - Fee Related legal-status Critical Current
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JP2014525437A 2011-08-17 2012-08-15 4−(8−メトキシ−1−((1−メトキシプロパン−2−イル)−2−(テトラヒドロ−2H−ピラン−4−イル)−1H−イミダゾ[4,5−c]キノリン−7−イル)−3,5−ジメチルイソオキサゾールおよびブロモドメイン阻害剤としてのその使用 Expired - Fee Related JP6059723B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1114103.3 2011-08-17
GBGB1114103.3A GB201114103D0 (en) 2011-08-17 2011-08-17 Novel compounds
PCT/EP2012/065918 WO2013024104A1 (en) 2011-08-17 2012-08-15 4-(8-methoxy-1-((1-methoxypropan-2-yl)-2-(tetrahydro-2h-pyran-4-yl)-1 h-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole and its use as bromodomain inhibitor

Publications (3)

Publication Number Publication Date
JP2014521735A JP2014521735A (ja) 2014-08-28
JP2014521735A5 true JP2014521735A5 (enExample) 2015-09-10
JP6059723B2 JP6059723B2 (ja) 2017-01-11

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ID=44764570

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JP2014525437A Expired - Fee Related JP6059723B2 (ja) 2011-08-17 2012-08-15 4−(8−メトキシ−1−((1−メトキシプロパン−2−イル)−2−(テトラヒドロ−2H−ピラン−4−イル)−1H−イミダゾ[4,5−c]キノリン−7−イル)−3,5−ジメチルイソオキサゾールおよびブロモドメイン阻害剤としてのその使用

Country Status (38)

Country Link
US (4) US9067936B2 (enExample)
EP (2) EP3150601A1 (enExample)
JP (1) JP6059723B2 (enExample)
KR (1) KR20140064878A (enExample)
CN (1) CN103889984B (enExample)
AR (1) AR087545A1 (enExample)
AU (1) AU2012296914B2 (enExample)
BR (1) BR112014003681A8 (enExample)
CA (1) CA2843537A1 (enExample)
CL (1) CL2014000365A1 (enExample)
CO (1) CO6862151A2 (enExample)
CR (1) CR20140076A (enExample)
CY (1) CY1118370T1 (enExample)
DK (1) DK2744809T3 (enExample)
DO (1) DOP2014000031A (enExample)
EA (1) EA023374B1 (enExample)
ES (1) ES2609857T3 (enExample)
GB (1) GB201114103D0 (enExample)
HR (1) HRP20161674T1 (enExample)
HU (1) HUE030106T2 (enExample)
IL (1) IL230489A (enExample)
IN (1) IN2014CN00568A (enExample)
JO (1) JO3187B1 (enExample)
LT (1) LT2744809T (enExample)
ME (1) ME02589B (enExample)
MX (1) MX350597B (enExample)
MY (1) MY170729A (enExample)
PE (1) PE20141406A1 (enExample)
PH (1) PH12014500379A1 (enExample)
PL (1) PL2744809T3 (enExample)
PT (1) PT2744809T (enExample)
RS (1) RS55560B1 (enExample)
SI (1) SI2744809T1 (enExample)
SM (2) SMT201700005T1 (enExample)
TW (1) TWI558704B (enExample)
UA (1) UA110838C2 (enExample)
UY (1) UY34264A (enExample)
WO (1) WO2013024104A1 (enExample)

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WO2015081189A1 (en) 2013-11-26 2015-06-04 Incyte Corporation Bicyclic heterocycles as bet protein inhibitors
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WO2015131005A1 (en) 2014-02-28 2015-09-03 The Regents Of The University Of Michigan 9h-pyrimido[4,5-b]indoles and related analogs as bet bromodomain inhibitors
SI3674302T1 (sl) 2014-04-23 2023-07-31 Incyte Holdings Corporation 1h-pirolo(2,3-c)piridin-7(6h)-oni in pirazolo(3,4-c)piridin-7(6h)-oni kot zaviralci proteinov bet
PT3157928T (pt) 2014-06-20 2019-05-30 Constellation Pharmaceuticals Inc Formas cristalinas de 2-((4s)-6-(4-clorofenil)-1-metil-4h-benzo[c] isoxazolo[4,5-e]azepin-4-il)acetamida
ES2855225T3 (es) 2014-09-15 2021-09-23 Incyte Corp Heterociclos tricíclicos para su uso como inhibidores de proteínas BET
CA2966298A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Ltd. Substituted pyridinones as bromodomain inhibitors
CA2966303A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Ltd. Substituted pyridines as bromodomain inhibitors
WO2016092375A1 (en) 2014-12-11 2016-06-16 Zenith Epigenetics Corp. Substituted heterocycles as bromodomain inhibitors
CN107406438B (zh) 2014-12-17 2021-05-14 恒翼生物医药科技(上海)有限公司 溴结构域的抑制剂
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US10501438B2 (en) 2015-08-11 2019-12-10 Neomed Institute Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals
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US10501459B2 (en) 2015-10-21 2019-12-10 Neomed Institute Substituted imidazo[1,2-a]pyridines as bromodomain inhibitors
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WO2018144789A1 (en) 2017-02-03 2018-08-09 The Regents Of The University Of Michigan Fused 1,4-diazepines as bet bromodomain inhibitors
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