JP2016501221A5 - - Google Patents

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Publication number
JP2016501221A5
JP2016501221A5 JP2015545145A JP2015545145A JP2016501221A5 JP 2016501221 A5 JP2016501221 A5 JP 2016501221A5 JP 2015545145 A JP2015545145 A JP 2015545145A JP 2015545145 A JP2015545145 A JP 2015545145A JP 2016501221 A5 JP2016501221 A5 JP 2016501221A5
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JP
Japan
Prior art keywords
inhibitor
pharmaceutical composition
composition according
cdk4
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2015545145A
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English (en)
Japanese (ja)
Other versions
JP2016501221A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/071659 external-priority patent/WO2014085318A1/en
Publication of JP2016501221A publication Critical patent/JP2016501221A/ja
Publication of JP2016501221A5 publication Critical patent/JP2016501221A5/ja
Withdrawn legal-status Critical Current

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JP2015545145A 2012-11-28 2013-11-25 併用療法 Withdrawn JP2016501221A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261730661P 2012-11-28 2012-11-28
US61/730,661 2012-11-28
PCT/US2013/071659 WO2014085318A1 (en) 2012-11-28 2013-11-25 Combination therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018176231A Division JP2019031500A (ja) 2012-11-28 2018-09-20 併用療法

Publications (2)

Publication Number Publication Date
JP2016501221A JP2016501221A (ja) 2016-01-18
JP2016501221A5 true JP2016501221A5 (enExample) 2017-01-12

Family

ID=49753505

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015545145A Withdrawn JP2016501221A (ja) 2012-11-28 2013-11-25 併用療法
JP2018176231A Withdrawn JP2019031500A (ja) 2012-11-28 2018-09-20 併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018176231A Withdrawn JP2019031500A (ja) 2012-11-28 2018-09-20 併用療法

Country Status (12)

Country Link
US (1) US9408847B2 (enExample)
EP (1) EP2925365A1 (enExample)
JP (2) JP2016501221A (enExample)
KR (1) KR20150089053A (enExample)
CN (1) CN104812414A (enExample)
AU (4) AU2013352406A1 (enExample)
BR (1) BR112015012197A8 (enExample)
CA (1) CA2891938A1 (enExample)
HK (1) HK1211475A1 (enExample)
MX (1) MX2015006809A (enExample)
RU (1) RU2015125307A (enExample)
WO (1) WO2014085318A1 (enExample)

Families Citing this family (31)

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US9271988B2 (en) * 2011-07-01 2016-03-01 Novartis Ag Combination therapy comprising a CDK4/6 inhibitor and a P13K inhibitor for use in the treatment of cancer
JP6430483B2 (ja) 2013-03-15 2018-11-28 ジー1、セラピューティクス、インコーポレイテッドG1 Therapeutics, Inc. 化学療法の間の正常細胞の一時的な保護
EP3049442A4 (en) 2013-09-26 2017-06-28 Costim Pharmaceuticals Inc. Methods for treating hematologic cancers
UA122479C2 (uk) 2014-01-24 2020-11-25 Дана-Фарбер Кенсер Інстітьют, Інк. Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
PL3099717T3 (pl) 2014-01-31 2019-10-31 Novartis Ag Cząsteczki przeciwciała dla TIM-3 i ich zastosowanie
EA201691765A1 (ru) 2014-03-14 2016-12-30 Новартис Аг Молекулы антител против lag-3 и их применения
ES2939940T3 (es) 2014-03-28 2023-04-28 Univ Duke Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
EP3191126B1 (en) 2014-09-13 2020-05-13 Novartis AG Combination therapies of alk inhibitors
KR20170066546A (ko) 2014-10-03 2017-06-14 노파르티스 아게 조합 요법
MA41044A (fr) 2014-10-08 2017-08-15 Novartis Ag Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
SG11201702401RA (en) 2014-10-14 2017-04-27 Novartis Ag Antibody molecules to pd-l1 and uses thereof
TWI706958B (zh) 2015-03-10 2020-10-11 美商艾杜諾生物科技公司 活化「干擾素基因刺激因子」依賴性訊息傳導之組合物及方法
CN106336412A (zh) * 2015-07-10 2017-01-18 南开大学 作为cdk4/6抑制剂的2-(n-氧化芳环-2基氨基)-吡咯并嘧啶及嘌呤类化合物
US20180340025A1 (en) 2015-07-29 2018-11-29 Novartis Ag Combination therapies comprising antibody molecules to lag-3
US20180207273A1 (en) 2015-07-29 2018-07-26 Novartis Ag Combination therapies comprising antibody molecules to tim-3
EP3328418A1 (en) 2015-07-29 2018-06-06 Novartis AG Combination therapies comprising antibody molecules to pd-1
EP3156406A1 (en) * 2015-10-14 2017-04-19 ratiopharm GmbH Crystalline forms of ribociclib free base
PT3370768T (pt) 2015-11-03 2022-04-21 Janssen Biotech Inc Anticorpos que se ligam especificamente ao pd-1 e seus usos
CN108495651A (zh) 2015-12-17 2018-09-04 诺华股份有限公司 抗pd-1的抗体分子及其用途
WO2017223115A1 (en) * 2016-06-22 2017-12-28 Radius Health, Inc. Ar+ breast cancer treatment methods
EP3507367A4 (en) 2016-07-05 2020-03-25 Aduro BioTech, Inc. CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
WO2018081211A1 (en) * 2016-10-26 2018-05-03 Li George Y Deuterated 7-cyclopentyl-n, n-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7h-pyrrolo[2,3-d]pyrimdine-6-carboxamide
WO2018170447A1 (en) 2017-03-16 2018-09-20 Eisai R&D Management Co., Ltd. Combination therapies for the treatment of breast cancer
UY37695A (es) 2017-04-28 2018-11-30 Novartis Ag Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
US20200172628A1 (en) 2017-06-22 2020-06-04 Novartis Ag Antibody molecules to cd73 and uses thereof
MX2019015885A (es) 2017-06-22 2020-09-10 Novartis Ag Moleculas de anticuerpo que se unen a cd73 y usos de las mismas.
US12398209B2 (en) 2018-01-22 2025-08-26 Janssen Biotech, Inc. Methods of treating cancers with antagonistic anti-PD-1 antibodies
WO2019232244A2 (en) 2018-05-31 2019-12-05 Novartis Ag Antibody molecules to cd73 and uses thereof
WO2020103922A1 (en) * 2018-11-23 2020-05-28 Ascentage Pharma (Suzhou) Co., Ltd. Novel pharmaceutical composition and use thereof
US10988479B1 (en) 2020-06-15 2021-04-27 G1 Therapeutics, Inc. Morphic forms of trilaciclib and methods of manufacture thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130035336A1 (en) * 2010-04-13 2013-02-07 Novartis Ag Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase (cdk4/6) inhibitor for treating cancer

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