JP2014516536A5 - - Google Patents

Info

Publication number

JP2014516536A5

JP2014516536A5 JP2014511948A JP2014511948A JP2014516536A5 JP 2014516536 A5 JP2014516536 A5 JP 2014516536A5 JP 2014511948 A JP2014511948 A JP 2014511948A JP 2014511948 A JP2014511948 A JP 2014511948A JP 2014516536 A5 JP2014516536 A5 JP 2014516536A5

Authority

JP

Japan

Prior art keywords

sequence

vector

vector according

immunogenic composition

seq

Prior art date

2012-05-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000013598 vector Substances 0.000 claims 19
• 230000002163 immunogen Effects 0.000 claims 9
• 108020004707 nucleic acids Proteins 0.000 claims 7
• 102000039446 nucleic acids Human genes 0.000 claims 7
• 150000007523 nucleic acids Chemical class 0.000 claims 7
• 239000002773 nucleotide Substances 0.000 claims 6
• 125000003729 nucleotide group Chemical group 0.000 claims 6
• 108091026890 Coding region Proteins 0.000 claims 5
• 108090000623 proteins and genes Proteins 0.000 claims 5
• 239000013603 viral vector Substances 0.000 claims 5
• 210000004436 artificial bacterial chromosome Anatomy 0.000 claims 4
• 210000004027 cell Anatomy 0.000 claims 4
• 241001465754 Metazoa Species 0.000 claims 3
• 125000003275 alpha amino acid group Chemical group 0.000 claims 3
• 210000000234 capsid Anatomy 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 230000028993 immune response Effects 0.000 claims 3
• 238000004806 packaging method and process Methods 0.000 claims 3
• 108091033319 polynucleotide Proteins 0.000 claims 3
• 102000040430 polynucleotide Human genes 0.000 claims 3
• 239000002157 polynucleotide Substances 0.000 claims 3
• 102000004169 proteins and genes Human genes 0.000 claims 3
• 241000701161 unidentified adenovirus Species 0.000 claims 3
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
• 108700026244 Open Reading Frames Proteins 0.000 claims 2
• 239000002671 adjuvant Substances 0.000 claims 2
• 239000000427 antigen Substances 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 230000003308 immunostimulating effect Effects 0.000 claims 2
• 230000001939 inductive effect Effects 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 229920001184 polypeptide Polymers 0.000 claims 2
• 108090000765 processed proteins & peptides Proteins 0.000 claims 2
• 102000004196 processed proteins & peptides Human genes 0.000 claims 2
• 241000894007 species Species 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 108090000565 Capsid Proteins Proteins 0.000 claims 1
• 102100023321 Ceruloplasmin Human genes 0.000 claims 1
• 241001217856 Chimpanzee adenovirus Species 0.000 claims 1
• 101710145505 Fiber protein Proteins 0.000 claims 1
• 101710094396 Hexon protein Proteins 0.000 claims 1
• 101710173835 Penton protein Proteins 0.000 claims 1
• 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
• 108010091086 Recombinases Proteins 0.000 claims 1
• 102000018120 Recombinases Human genes 0.000 claims 1
• 239000004480 active ingredient Substances 0.000 claims 1
• 210000004102 animal cell Anatomy 0.000 claims 1
• 102000036639 antigens Human genes 0.000 claims 1
• 108091007433 antigens Proteins 0.000 claims 1
• 239000003085 diluting agent Substances 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 238000001415 gene therapy Methods 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 108091070501 miRNA Proteins 0.000 claims 1
• 239000002679 microRNA Substances 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 238000013518 transcription Methods 0.000 claims 1
• 230000035897 transcription Effects 0.000 claims 1