JP2014515039A5 - - Google Patents
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- JP2014515039A5 JP2014515039A5 JP2014510928A JP2014510928A JP2014515039A5 JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5 JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5
- Authority
- JP
- Japan
- Prior art keywords
- polylactide
- oligo
- peg
- polypeptide
- chains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11166241 | 2011-05-16 | ||
| EP11166241.7 | 2011-05-16 | ||
| EP11166942.0 | 2011-05-20 | ||
| EP11166942 | 2011-05-20 | ||
| US201161515432P | 2011-08-05 | 2011-08-05 | |
| US201161515458P | 2011-08-05 | 2011-08-05 | |
| EP11176736.4 | 2011-08-05 | ||
| EP11176741.4 | 2011-08-05 | ||
| EP11176741 | 2011-08-05 | ||
| EP11176736 | 2011-08-05 | ||
| US61/515,458 | 2011-08-05 | ||
| US61/515,432 | 2011-08-05 | ||
| EP11192572 | 2011-12-08 | ||
| EP11192577.2 | 2011-12-08 | ||
| EP11192572.3 | 2011-12-08 | ||
| EP11192577 | 2011-12-08 | ||
| PCT/IB2012/052445 WO2012156918A1 (en) | 2011-05-16 | 2012-05-16 | Bio-orthogonal drug activation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014515039A JP2014515039A (ja) | 2014-06-26 |
| JP2014515039A5 true JP2014515039A5 (enExample) | 2017-03-02 |
| JP6215194B2 JP6215194B2 (ja) | 2017-10-18 |
Family
ID=47176369
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510928A Active JP6215194B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
| JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
| JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Country Status (9)
| Country | Link |
|---|---|
| US (8) | US20160151505A1 (enExample) |
| EP (4) | EP2709667B1 (enExample) |
| JP (5) | JP6482273B2 (enExample) |
| CN (4) | CN103732256A (enExample) |
| AU (3) | AU2012257417B2 (enExample) |
| CA (3) | CA2836361C (enExample) |
| DK (1) | DK2709667T3 (enExample) |
| ES (1) | ES2920373T3 (enExample) |
| WO (3) | WO2012156918A1 (enExample) |
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| US10179775B2 (en) | 2014-08-11 | 2019-01-15 | The General Hospital Corporation | Cyclooctenes for bioorthogonol reactions |
| WO2018004338A1 (en) | 2016-06-27 | 2018-01-04 | Tagworks Pharmaceuticals B.V. | Cleavable tetrazine used in bio-orthogonal drug activation |
| DK3788032T3 (da) * | 2018-05-04 | 2024-04-15 | Tagworks Pharmaceuticals B V | Forbindelser omfattende en linker til øgning af transcyklooctenstabilitet |
| CA3099419A1 (en) * | 2018-05-04 | 2019-11-07 | Tagworks Pharmaceuticals B.V. | Tetrazines for high click conjugation yield in vivo and high click release yield |
| IL289095A (en) * | 2019-06-17 | 2022-02-01 | Tagworks Pharmaceuticals B V | Activating components to cleave labels from biomolecules in vivo |
| IL289094A (en) * | 2019-06-17 | 2022-02-01 | Tagworks Pharmaceuticals B V | Tetrazines for increasing the speed and yield of the "click release" reaction |
| AU2020297253B2 (en) * | 2019-06-17 | 2024-05-23 | Tagworks Pharmaceuticals B.V. | Compounds for fast and efficient click release |
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2012
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- 2012-05-16 US US14/117,125 patent/US20160151505A1/en not_active Abandoned
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