JP2014515039A5 - - Google Patents
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- JP2014515039A5 JP2014515039A5 JP2014510928A JP2014510928A JP2014515039A5 JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5 JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5
- Authority
- JP
- Japan
- Prior art keywords
- polylactide
- oligo
- peg
- polypeptide
- chains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11166241 | 2011-05-16 | ||
| EP11166241.7 | 2011-05-16 | ||
| EP11166942 | 2011-05-20 | ||
| EP11166942.0 | 2011-05-20 | ||
| US201161515458P | 2011-08-05 | 2011-08-05 | |
| US201161515432P | 2011-08-05 | 2011-08-05 | |
| US61/515,432 | 2011-08-05 | ||
| EP11176741.4 | 2011-08-05 | ||
| EP11176741 | 2011-08-05 | ||
| US61/515,458 | 2011-08-05 | ||
| EP11176736 | 2011-08-05 | ||
| EP11176736.4 | 2011-08-05 | ||
| EP11192577.2 | 2011-12-08 | ||
| EP11192577 | 2011-12-08 | ||
| EP11192572.3 | 2011-12-08 | ||
| EP11192572 | 2011-12-08 | ||
| PCT/IB2012/052445 WO2012156918A1 (en) | 2011-05-16 | 2012-05-16 | Bio-orthogonal drug activation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014515039A JP2014515039A (ja) | 2014-06-26 |
| JP2014515039A5 true JP2014515039A5 (enExample) | 2017-03-02 |
| JP6215194B2 JP6215194B2 (ja) | 2017-10-18 |
Family
ID=47176369
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510928A Active JP6215194B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
| JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
| JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
| JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Country Status (9)
| Country | Link |
|---|---|
| US (8) | US9421274B2 (enExample) |
| EP (4) | EP2709666B1 (enExample) |
| JP (5) | JP5993940B2 (enExample) |
| CN (4) | CN103889459B (enExample) |
| AU (3) | AU2012257418B2 (enExample) |
| CA (3) | CA2836365C (enExample) |
| DK (1) | DK2709667T3 (enExample) |
| ES (1) | ES2920373T3 (enExample) |
| WO (3) | WO2012156918A1 (enExample) |
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| EP2522369A1 (en) * | 2011-05-09 | 2012-11-14 | Koninklijke Philips Electronics N.V. | Pretargeting kit, method and agents used therein |
| EP2709666B1 (en) | 2011-05-16 | 2021-07-14 | Koninklijke Philips N.V. | Bio-orthogonal drug activation |
| WO2014065860A1 (en) | 2012-10-24 | 2014-05-01 | The General Hospital Corporation | Functionalized 1,2,4,5-tetrazine compounds for use in bioorthogonal coupling reactions |
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| WO2016025480A1 (en) | 2014-08-11 | 2016-02-18 | The General Hospital Corporation | Cyclooctenes for bioorthogonol reactions |
| US11617799B2 (en) * | 2016-06-27 | 2023-04-04 | Tagworks Pharmaceuticals B.V. | Cleavable tetrazine used in bio-orthogonal drug activation |
| AU2019262521B2 (en) * | 2018-05-04 | 2024-04-18 | Tagworks Pharmaceuticals B.V. | Compounds comprising a linker for increasing transcyclooctene stability |
| CA3099419A1 (en) * | 2018-05-04 | 2019-11-07 | Tagworks Pharmaceuticals B.V. | Tetrazines for high click conjugation yield in vivo and high click release yield |
| WO2020256546A1 (en) * | 2019-06-17 | 2020-12-24 | Tagworks Pharmaceuticals B.V. | Compounds for fast and efficient click release |
| CA3143924C (en) * | 2019-06-17 | 2025-06-03 | Tagworks Pharmaceuticals B.V. | Agents that allow in vivo cleavage of markers linked to biomolecules |
| IL289094A (en) * | 2019-06-17 | 2022-02-01 | Tagworks Pharmaceuticals B V | Tetrazines for increasing the speed and yield of the "click release" reaction |
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