JP2014515039A5 - - Google Patents
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- JP2014515039A5 JP2014515039A5 JP2014510928A JP2014510928A JP2014515039A5 JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5 JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014510928 A JP2014510928 A JP 2014510928A JP 2014515039 A5 JP2014515039 A5 JP 2014515039A5
- Authority
- JP
- Japan
- Prior art keywords
- polylactide
- oligo
- peg
- polypeptide
- chains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 229920001222 biopolymer Polymers 0.000 description 1
- 229920000747 poly(lactic acid) polymer Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
Description
スペーサーSPは、限定されるものではないが、ポリエチレングリコール(PEG)鎖であり、2から200、特には3から113、及び好ましくは5から50の繰り返し単位を持つ。他の例は、生体ポリマー断片であり、例えばオリゴ又はポリペプチド又はポリラクチドである。さらには好ましい例は実施例15に示される。
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11166241.7 | 2011-05-16 | ||
EP11166241 | 2011-05-16 | ||
EP11166942.0 | 2011-05-20 | ||
EP11166942 | 2011-05-20 | ||
US201161515458P | 2011-08-05 | 2011-08-05 | |
US201161515432P | 2011-08-05 | 2011-08-05 | |
EP11176736 | 2011-08-05 | ||
US61/515,432 | 2011-08-05 | ||
US61/515,458 | 2011-08-05 | ||
EP11176741.4 | 2011-08-05 | ||
EP11176741 | 2011-08-05 | ||
EP11176736.4 | 2011-08-05 | ||
EP11192577.2 | 2011-12-08 | ||
EP11192572.3 | 2011-12-08 | ||
EP11192577 | 2011-12-08 | ||
EP11192572 | 2011-12-08 | ||
PCT/IB2012/052445 WO2012156918A1 (en) | 2011-05-16 | 2012-05-16 | Bio-orthogonal drug activation |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2014515039A JP2014515039A (ja) | 2014-06-26 |
JP2014515039A5 true JP2014515039A5 (ja) | 2017-03-02 |
JP6215194B2 JP6215194B2 (ja) | 2017-10-18 |
Family
ID=47176369
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
JP2014510928A Active JP6215194B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014510930A Active JP6482273B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
JP2014510929A Active JP5993940B2 (ja) | 2011-05-16 | 2012-05-16 | 生体直交型薬物活性化 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016161617A Ceased JP2017014262A (ja) | 2011-05-16 | 2016-08-22 | 生体直交型薬物活性化 |
JP2018000737A Active JP6608467B2 (ja) | 2011-05-16 | 2018-01-05 | 生体直交型薬物活性化 |
Country Status (9)
Country | Link |
---|---|
US (8) | US20160151505A1 (ja) |
EP (4) | EP2709667B1 (ja) |
JP (5) | JP6482273B2 (ja) |
CN (4) | CN103889459B (ja) |
AU (3) | AU2012257418B2 (ja) |
CA (3) | CA2836365C (ja) |
DK (1) | DK2709667T3 (ja) |
ES (1) | ES2920373T3 (ja) |
WO (3) | WO2012156920A1 (ja) |
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2012
- 2012-05-16 US US14/117,125 patent/US20160151505A1/en not_active Abandoned
- 2012-05-16 ES ES12725515T patent/ES2920373T3/es active Active
- 2012-05-16 CN CN201280035096.4A patent/CN103889459B/zh active Active
- 2012-05-16 DK DK12725515.6T patent/DK2709667T3/da active
- 2012-05-16 CN CN201280024028.8A patent/CN103732256A/zh active Pending
- 2012-05-16 AU AU2012257418A patent/AU2012257418B2/en active Active
- 2012-05-16 AU AU2012257417A patent/AU2012257417B2/en active Active
- 2012-05-16 AU AU2012257416A patent/AU2012257416B8/en active Active
- 2012-05-16 CN CN201280035091.1A patent/CN103732257A/zh active Pending
- 2012-05-16 CA CA2836365A patent/CA2836365C/en active Active
- 2012-05-16 WO PCT/IB2012/052447 patent/WO2012156920A1/en active Application Filing
- 2012-05-16 WO PCT/IB2012/052445 patent/WO2012156918A1/en active Application Filing
- 2012-05-16 WO PCT/IB2012/052446 patent/WO2012156919A1/en active Application Filing
- 2012-05-16 US US14/117,246 patent/US9421274B2/en active Active
- 2012-05-16 US US14/117,655 patent/US9931408B2/en active Active
- 2012-05-16 CN CN201810251663.9A patent/CN108524510A/zh active Pending
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- 2012-05-16 JP JP2014510930A patent/JP6482273B2/ja active Active
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- 2012-05-16 EP EP12725516.4A patent/EP2709668A1/en not_active Withdrawn
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2015
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2018
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2019
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2021
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2023
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