JP2014507391A5 - - Google Patents

Download PDF

Info

Publication number
JP2014507391A5
JP2014507391A5 JP2013544829A JP2013544829A JP2014507391A5 JP 2014507391 A5 JP2014507391 A5 JP 2014507391A5 JP 2013544829 A JP2013544829 A JP 2013544829A JP 2013544829 A JP2013544829 A JP 2013544829A JP 2014507391 A5 JP2014507391 A5 JP 2014507391A5
Authority
JP
Japan
Prior art keywords
methanol
alcohol
pharmaceutical composition
isoperyl
isopropylcyclohexa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013544829A
Other languages
English (en)
Japanese (ja)
Other versions
JP6122564B2 (ja
JP2014507391A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/065513 external-priority patent/WO2012083178A1/en
Publication of JP2014507391A publication Critical patent/JP2014507391A/ja
Publication of JP2014507391A5 publication Critical patent/JP2014507391A5/ja
Application granted granted Critical
Publication of JP6122564B2 publication Critical patent/JP6122564B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013544829A 2010-12-17 2011-12-16 イソペリリルアルコールの使用方法および装置 Active JP6122564B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061424332P 2010-12-17 2010-12-17
US61/424,332 2010-12-17
US201161436365P 2011-01-26 2011-01-26
US61/436,365 2011-01-26
PCT/US2011/065513 WO2012083178A1 (en) 2010-12-17 2011-12-16 Methods and devices for using isoperillyl alcohol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017019540A Division JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Publications (3)

Publication Number Publication Date
JP2014507391A JP2014507391A (ja) 2014-03-27
JP2014507391A5 true JP2014507391A5 (enExample) 2015-02-12
JP6122564B2 JP6122564B2 (ja) 2017-04-26

Family

ID=46245128

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013544829A Active JP6122564B2 (ja) 2010-12-17 2011-12-16 イソペリリルアルコールの使用方法および装置
JP2017019540A Pending JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017019540A Pending JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Country Status (7)

Country Link
US (4) US9211269B2 (enExample)
EP (4) EP2651864B1 (enExample)
JP (2) JP6122564B2 (enExample)
CN (2) CN105616391B (enExample)
BR (1) BR112013015107B1 (enExample)
DK (1) DK2651864T3 (enExample)
WO (1) WO2012083178A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11147809B2 (en) 2010-08-27 2021-10-19 Neonc Technologies, Inc. Methods of treating neurofibromatosis with perillyl alcohol
WO2018005994A1 (en) * 2016-07-01 2018-01-04 Neonc Technologies, Inc. Methods of treating neurofibromatosis with perillyl alcohol
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
EP2651864B1 (en) * 2010-12-17 2016-07-13 Neonc Technologies Inc. Methods and devices for using isoperillyl alcohol
CN107613768B (zh) * 2015-02-12 2020-10-20 NeOnc技术股份有限公司 包含紫苏醇衍生物的药物组合物
CN110769831A (zh) * 2017-04-19 2020-02-07 尼昂克技术公司 包含poh衍生物的药物组合物及使用方法
WO2019014420A1 (en) * 2017-07-12 2019-01-17 Azhc, Llc COMPOSITIONS AND METHODS FOR REDUCING MEDICATION ERRORS
EP3749291B1 (en) * 2018-02-08 2024-01-03 University of Southern California Methods of permeabilizing the blood brain barrier
CN113943312A (zh) * 2020-07-17 2022-01-18 轶诺(浙江)药业有限公司 一类肠道裂解型共药及其制备和用途
TW202227401A (zh) * 2020-10-23 2022-07-16 大陸商重慶兩江藥物研發中心有限公司 用於持續釋放治療劑的前藥及其用途
EP4294513A1 (en) 2021-02-19 2023-12-27 Mevion Medical Systems, Inc. Gantry for a particle therapy system
JP2024516413A (ja) * 2021-04-28 2024-04-15 ネオンク テクノロジーズ インク． レボドパ送達を増強するためのペリリルアルコールの使用
CN116789530A (zh) * 2023-05-16 2023-09-22 杭州师范大学 一种紫苏醇酚类衍生物及其制备方法和应用

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8007911A (pt) 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
EP0069715B1 (en) 1981-07-08 1986-11-05 Aktiebolaget Draco Powder inhalator
DK163640C (da) 1985-07-30 1992-08-17 Glaxo Group Ltd Apparat til administrering af medikamenter
US4738851A (en) 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US4882150A (en) 1988-06-03 1989-11-21 Kaufman Herbert E Drug delivery system
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5521222A (en) 1989-09-28 1996-05-28 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
US6313176B1 (en) 1989-10-17 2001-11-06 Everett J. Ellinwood, Jr. Dosing method of administering deprenyl via intraoral administration or inhalation administration
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
US5077033A (en) 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US6006745A (en) 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
DE69212850T2 (de) 1991-01-15 1997-03-06 Alcon Lab Inc Verwendung von Karrageenan in topischen ophthalmologischen Zusammensetzungen
US5874063A (en) 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
AU2178392A (en) 1991-06-12 1993-01-12 Minnesota Mining And Manufacturing Company Albuterol sulfate suspension aerosol formulations
US5337740A (en) 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
EP0617610B1 (en) 1991-12-18 1997-03-19 Minnesota Mining And Manufacturing Company Suspension aerosol formulations
US5587402A (en) 1992-04-09 1996-12-24 Wisconsin Alumni Research Foundation Regression of mammalian leukemia cell tumors
US5470877A (en) * 1992-04-09 1995-11-28 Wisconsin Alumni Research Foundation Uses of perillic acid methyl ester
US5239993A (en) 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
US5602184A (en) 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
US5497763A (en) 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
JPH0748264A (ja) 1993-08-06 1995-02-21 Nippon Terupen Kagaku Kk アルドース還元酵素阻害剤
US5415162A (en) 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
DE69433818T2 (de) 1994-01-28 2005-06-16 The University Of Kentucky Research Foundation Co-pharmaka als ein verfahren des kontrollierten arzneimitteltransportes
IL114193A (en) 1994-06-20 2000-02-29 Teva Pharma Ophthalmic pharmaceutical compositions based on sodium alginate
ES2094688B1 (es) 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
IT1283911B1 (it) 1996-02-05 1998-05-07 Farmigea Spa Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo
US6040344A (en) 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US5800807A (en) 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US6143227A (en) 1997-07-30 2000-11-07 Visteon Global Technologies, Inc. Method for injection molding an article having film covered flanges
US5994598A (en) 1998-01-15 1999-11-30 Doyle E. Chastain Method of preparing perillyl alcohol and perillyl acetate
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
PT1073417E (pt) 1998-04-18 2003-04-30 Glaxo Group Ltd Formulacao farmaceutica em aerossol
GB9808802D0 (en) 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
US6197934B1 (en) 1998-05-22 2001-03-06 Collagenesis, Inc. Compound delivery using rapidly dissolving collagen film
SE9804000D0 (sv) 1998-11-23 1998-11-23 Astra Ab New composition of matter
WO2000037434A1 (en) * 1998-12-22 2000-06-29 Mitsubishi Chemical Corporation Amide derivatives
PT1169019E (pt) 1999-04-14 2003-07-31 Glaxo Group Ltd Formulacao farmaceutica em aerossol
US7056491B2 (en) * 2000-11-08 2006-06-06 Wisconsin Alumni Research Foundation Monoterpenes and sesquiterpenes as chemotherapeutic and radiation sensitizers and immunomodulators
EP1236802A1 (en) * 2001-02-16 2002-09-04 Aventis Animal Nutrition S.A. Process for the preparation of perillyl alcohol
JP4634694B2 (ja) * 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪アルコール薬物複合体
AU2002350207A1 (en) * 2001-11-19 2003-06-10 Control Delivery Systems, Inc. Topical delivery of codrugs
US20060104997A1 (en) * 2001-12-11 2006-05-18 Constantinides Panayiotis P Monoterpene compositions and uses thereof
BR0107262B1 (pt) 2001-12-17 2014-04-22 Da Fonseca Clovis Orlando Pereira Composição farmacêutica inalatória
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
WO2004101605A1 (en) 2003-03-05 2004-11-25 Boehringer Ingelheim International Gmbh Hepatitis c inhibiting compounds
US7015349B2 (en) * 2003-03-26 2006-03-21 The Gillette Company Reduction of hair growth
GB2414395B (en) 2003-03-26 2007-10-31 Kringle Pharma Inc Asthma preparation
EP1656133A4 (en) 2003-08-15 2008-10-29 Merck & Co Inc INHIBITORS OF MITOTIC KINESINE
US7297714B2 (en) * 2003-10-21 2007-11-20 Irm Llc Inhibitors of cathepsin S
EP1868653A2 (en) 2005-04-12 2007-12-26 PSivida Inc. Hmgcoa reductase inhibitor codrugs and uses thereof
US7601355B2 (en) 2005-06-01 2009-10-13 Northwestern University Compositions and methods for altering immune function
MY139923A (en) 2005-07-29 2009-11-30 Tibotec Pharm Ltd Macrocylic inhibitors of hepatitis c virus
WO2007025286A2 (en) 2005-08-26 2007-03-01 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
WO2008016652A2 (en) 2006-07-31 2008-02-07 Bio-Tree Systems, Inc. Blood vessel imaging and uses therefor
US7803940B2 (en) 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
DK3567035T3 (da) 2007-04-11 2022-09-05 Canbas Co Ltd N-substituerede 2,5-dioxo-azolin-forbindelser til anvendelse ved behandling af cancer
US8889622B2 (en) 2007-07-25 2014-11-18 Washington University Methods of inhibiting seizure in a subject
US7745670B2 (en) 2008-06-27 2010-06-29 Codman & Shurtleff, Inc. Curcumin-Resveratrol hybrid molecule
CA2725143A1 (en) 2008-05-21 2009-11-26 Neurotez, Inc. Methods for treating progressive cognitive disorders related to neurofibrillary tangles
CN101584660B (zh) * 2008-05-21 2011-06-08 河南省医药科学研究院 静脉注射紫苏醇亚微乳及其制备方法
US8058469B2 (en) 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
CN102405044A (zh) * 2009-02-06 2012-04-04 南加利福尼亚大学 含有单萜的治疗组合物
US8822476B2 (en) * 2009-04-02 2014-09-02 Merck Patent Gmbh Piperidine and piperazine derivatives as autotaxin inhibitors
CN104744215B (zh) 2010-03-03 2019-03-15 尼昂克技术公司 包含单萜的药物组合物
CN110464718A (zh) * 2010-08-27 2019-11-19 尼昂克技术公司 包含poh衍生物的药物组合物
US9651554B2 (en) 2010-09-24 2017-05-16 The Methodist Hospital Research Institute Molecular diagnostic methods for predicting brain metastasis of breast cancer
EP2651864B1 (en) * 2010-12-17 2016-07-13 Neonc Technologies Inc. Methods and devices for using isoperillyl alcohol

Similar Documents

Publication Publication Date Title
JP2014507391A5 (enExample)
KR101638035B1 (ko) 핵 수용체에 결합하는 물질
JP2014505008A5 (enExample)
JP6510485B2 (ja) Ｐｒｍｔ５インヒビターおよびそれらの使用方法
JP5797755B2 (ja) Ｐｏｈ誘導体を含む医薬組成物
US9963452B2 (en) Methods, compounds, and compositions for inhibition of ROS
JP2012514655A (ja) フッ素含有化合物およびその使用法
US11382916B2 (en) Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof
JP2017519754A5 (enExample)
US10730830B2 (en) Tetrahydronaphthalene derivative
US20130053418A1 (en) Acyclic organonitro compounds for use in treating cancer
JP2015505301A5 (enExample)
TWI757726B (zh) 4(1h)-奎諾酮衍生物及其用途
US20170334855A1 (en) Kcnq2-5 channel activator
JP2019189644A (ja) 抗癌剤およびその調製方法
US20230257383A1 (en) Compound serving as btk inhibitor, preparation method therefor, and use thereof
JP2017503753A5 (enExample)
TW202114984A (zh) 具有ｓ１ｐ受體作動活性的化合物的鹽及結晶形
CN117062819A (zh) 多环化合物及其用途
JP2022031509A (ja) アンドロゲン依存性又は非依存性前立腺癌細胞の抑制用の組成物及びそれを含有する前立腺癌の医薬製剤
JP2015502352A5 (enExample)
EP2782894A2 (en) Pharmaceutical compositions comprising deuterium-enriched perillyl alcohol, iso-perillyl alcohol and derivatives thereof
EP3654959A2 (en) Compositions and methods for treatment of central nervous system tumors
JP2011500841A5 (enExample)
JP2007507470A (ja) ヒトｏｒｌ１受容体に対するアゴニストとしてのビシクロ’３．１．１！ヘプタン置換ベンズイミダゾロン及びキナゾリノン誘導体