JP2014507391A5 - - Google Patents

Download PDF

Info

Publication number
JP2014507391A5
JP2014507391A5 JP2013544829A JP2013544829A JP2014507391A5 JP 2014507391 A5 JP2014507391 A5 JP 2014507391A5 JP 2013544829 A JP2013544829 A JP 2013544829A JP 2013544829 A JP2013544829 A JP 2013544829A JP 2014507391 A5 JP2014507391 A5 JP 2014507391A5
Authority
JP
Japan
Prior art keywords
methanol
alcohol
pharmaceutical composition
isoperyl
isopropylcyclohexa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013544829A
Other languages
English (en)
Japanese (ja)
Other versions
JP6122564B2 (ja
JP2014507391A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/065513 external-priority patent/WO2012083178A1/en
Publication of JP2014507391A publication Critical patent/JP2014507391A/ja
Publication of JP2014507391A5 publication Critical patent/JP2014507391A5/ja
Application granted granted Critical
Publication of JP6122564B2 publication Critical patent/JP6122564B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013544829A 2010-12-17 2011-12-16 イソペリリルアルコールの使用方法および装置 Active JP6122564B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061424332P 2010-12-17 2010-12-17
US61/424,332 2010-12-17
US201161436365P 2011-01-26 2011-01-26
US61/436,365 2011-01-26
PCT/US2011/065513 WO2012083178A1 (en) 2010-12-17 2011-12-16 Methods and devices for using isoperillyl alcohol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017019540A Division JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Publications (3)

Publication Number Publication Date
JP2014507391A JP2014507391A (ja) 2014-03-27
JP2014507391A5 true JP2014507391A5 (enExample) 2015-02-12
JP6122564B2 JP6122564B2 (ja) 2017-04-26

Family

ID=46245128

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013544829A Active JP6122564B2 (ja) 2010-12-17 2011-12-16 イソペリリルアルコールの使用方法および装置
JP2017019540A Pending JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017019540A Pending JP2017125024A (ja) 2010-12-17 2017-02-06 イソペリリルアルコールの使用方法および装置

Country Status (8)

Country Link
US (4) US9211269B2 (enExample)
EP (4) EP2651864B1 (enExample)
JP (2) JP6122564B2 (enExample)
CN (2) CN103517892B (enExample)
BR (1) BR112013015107B1 (enExample)
DK (2) DK2651864T3 (enExample)
ES (1) ES3056006T3 (enExample)
WO (1) WO2012083178A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160038600A1 (en) * 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
WO2018005994A1 (en) * 2016-07-01 2018-01-04 Neonc Technologies, Inc. Methods of treating neurofibromatosis with perillyl alcohol
US11147809B2 (en) 2010-08-27 2021-10-19 Neonc Technologies, Inc. Methods of treating neurofibromatosis with perillyl alcohol
ES3056006T3 (en) * 2010-12-17 2026-02-17 Univ Southern California Methods and devices for using isoperillyl alcohol
WO2016130800A2 (en) * 2015-02-12 2016-08-18 Neonc Technologies Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
US11559508B2 (en) 2017-04-19 2023-01-24 Neonc Technologies, Inc. Pharmaceutical compositions comprising POH derivatives and methods of use
WO2019014420A1 (en) * 2017-07-12 2019-01-17 Azhc, Llc COMPOSITIONS AND METHODS FOR REDUCING MEDICATION ERRORS
JP7325425B2 (ja) 2018-02-08 2023-08-14 ネオンク テクノロジーズ インク. 血液脳関門を透過性にする方法
CN113943312A (zh) * 2020-07-17 2022-01-18 轶诺(浙江)药业有限公司 一类肠道裂解型共药及其制备和用途
TW202227401A (zh) * 2020-10-23 2022-07-16 大陸商重慶兩江藥物研發中心有限公司 用於持續釋放治療劑的前藥及其用途
US12245355B2 (en) 2021-02-19 2025-03-04 Mevion Medical Systems, Inc. Gantry for a particle therapy system
JP2024516413A (ja) * 2021-04-28 2024-04-15 ネオンク テクノロジーズ インク. レボドパ送達を増強するためのペリリルアルコールの使用
CN116789530B (zh) * 2023-05-16 2025-12-19 杭州师范大学 一种紫苏醇酚类衍生物及其制备方法和应用

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8007911A (pt) 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
EP0069715B1 (en) 1981-07-08 1986-11-05 Aktiebolaget Draco Powder inhalator
AU591152B2 (en) 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
US4738851A (en) 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US4882150A (en) 1988-06-03 1989-11-21 Kaufman Herbert E Drug delivery system
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5521222A (en) 1989-09-28 1996-05-28 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
US6313176B1 (en) 1989-10-17 2001-11-06 Everett J. Ellinwood, Jr. Dosing method of administering deprenyl via intraoral administration or inhalation administration
SK280968B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
US5077033A (en) 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US6006745A (en) 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
DK0495421T3 (da) 1991-01-15 1996-12-09 Alcon Lab Inc Anvendelse af carragenaner i topiske ophthalmiske sammensætninger
US5874063A (en) 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
WO1992022286A1 (en) 1991-06-12 1992-12-23 Minnesota Mining And Manufacturing Company Albuterol sulfate suspension aerosol formulations
US5337740A (en) 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
DK0717987T3 (da) 1991-12-18 2001-11-12 Minnesota Mining & Mfg Suspension-aerosol-formuleringer
US5587402A (en) 1992-04-09 1996-12-24 Wisconsin Alumni Research Foundation Regression of mammalian leukemia cell tumors
US5470877A (en) * 1992-04-09 1995-11-28 Wisconsin Alumni Research Foundation Uses of perillic acid methyl ester
US5239993A (en) 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
US5602184A (en) 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
US5497763A (en) 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
JPH0748264A (ja) 1993-08-06 1995-02-21 Nippon Terupen Kagaku Kk アルドース還元酵素阻害剤
US5415162A (en) 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
PT740650E (pt) * 1994-01-28 2004-10-29 Univ Kentucky Res Found Co-farmacos como um metodo de administracao controlada de farmacos
IL114193A (en) 1994-06-20 2000-02-29 Teva Pharma Ophthalmic pharmaceutical compositions based on sodium alginate
ES2094688B1 (es) 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
IT1283911B1 (it) 1996-02-05 1998-05-07 Farmigea Spa Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo
US6040344A (en) 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US5800807A (en) 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US6143227A (en) 1997-07-30 2000-11-07 Visteon Global Technologies, Inc. Method for injection molding an article having film covered flanges
US5994598A (en) 1998-01-15 1999-11-30 Doyle E. Chastain Method of preparing perillyl alcohol and perillyl acetate
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
ID27887A (id) 1998-04-18 2001-05-03 Glaxo Group Ltd Formulasi aerosol farmasi
GB9808802D0 (en) 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
US6197934B1 (en) 1998-05-22 2001-03-06 Collagenesis, Inc. Compound delivery using rapidly dissolving collagen film
SE9804000D0 (sv) 1998-11-23 1998-11-23 Astra Ab New composition of matter
EP1142868A4 (en) 1998-12-22 2004-09-29 Mitsubishi Chem Corp AMIDE DERIVATIVES
EP1169019B1 (en) 1999-04-14 2003-02-26 Glaxo Group Limited Pharmaceutical aerosol formulation
US7056491B2 (en) 2000-11-08 2006-06-06 Wisconsin Alumni Research Foundation Monoterpenes and sesquiterpenes as chemotherapeutic and radiation sensitizers and immunomodulators
EP1236802A1 (en) * 2001-02-16 2002-09-04 Aventis Animal Nutrition S.A. Process for the preparation of perillyl alcohol
AU2002305099A1 (en) * 2001-03-23 2002-10-08 Protarga, Inc. Fatty alcohol drug conjugates
US20030118528A1 (en) 2001-11-19 2003-06-26 Walters Kenneth A. Topical delivery of codrugs
US20060104997A1 (en) * 2001-12-11 2006-05-18 Constantinides Panayiotis P Monoterpene compositions and uses thereof
BR0107262B1 (pt) 2001-12-17 2014-04-22 Da Fonseca Clovis Orlando Pereira Composição farmacêutica inalatória
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
JP4550824B2 (ja) * 2003-03-05 2010-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング C型肝炎抑制化合物
US7563768B2 (en) 2003-03-26 2009-07-21 Kringle Pharma Inc. Asthma preparation
US7015349B2 (en) * 2003-03-26 2006-03-21 The Gillette Company Reduction of hair growth
US7638549B2 (en) 2003-08-15 2009-12-29 Merck & Co. Inc. Mitotic kinesin inhibitors
US7297714B2 (en) 2003-10-21 2007-11-20 Irm Llc Inhibitors of cathepsin S
WO2006110882A2 (en) 2005-04-12 2006-10-19 Psivida Inc. Hmgcoa reductase inhibitor codrugs and uses thereof
US7601355B2 (en) 2005-06-01 2009-10-13 Northwestern University Compositions and methods for altering immune function
BRPI0614637A2 (pt) 2005-07-29 2011-04-12 Tibotec Pharm Ltd inibidores macrocìclicos do vìrus da hepatite c
JP5276982B2 (ja) 2005-08-26 2013-08-28 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ オキシトシンの投与による頭痛の処置のための方法
EP2086412A2 (en) 2006-07-31 2009-08-12 Bio-Tree Systems, Inc. Blood vessel imaging and uses therefor
US7803940B2 (en) 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
DK3567035T3 (da) 2007-04-11 2022-09-05 Canbas Co Ltd N-substituerede 2,5-dioxo-azolin-forbindelser til anvendelse ved behandling af cancer
US8889622B2 (en) 2007-07-25 2014-11-18 Washington University Methods of inhibiting seizure in a subject
US7745670B2 (en) 2008-06-27 2010-06-29 Codman & Shurtleff, Inc. Curcumin-Resveratrol hybrid molecule
KR20110028457A (ko) 2008-05-21 2011-03-18 뉴로테즈 인코포레이티드 신경섬유 매듭과 연관된 신경변성 장애를 치료하는 방법
CN101584660B (zh) * 2008-05-21 2011-06-08 河南省医药科学研究院 静脉注射紫苏醇亚微乳及其制备方法
US8058469B2 (en) 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP3620154A1 (en) * 2009-02-06 2020-03-11 University Of Southern California Therapeutic compositions comprising monoterpenes
AU2010234087B2 (en) * 2009-04-02 2016-05-12 Merck Patent Gmbh Piperidine and piperazine derivatives as autotaxin inhibitors
CN104744215B (zh) 2010-03-03 2019-03-15 尼昂克技术公司 包含单萜的药物组合物
US9499461B2 (en) * 2010-08-27 2016-11-22 Neonc Technologies, Inc. Pharmaceutical compositions comprising POH derivatives
US9651554B2 (en) 2010-09-24 2017-05-16 The Methodist Hospital Research Institute Molecular diagnostic methods for predicting brain metastasis of breast cancer
ES3056006T3 (en) 2010-12-17 2026-02-17 Univ Southern California Methods and devices for using isoperillyl alcohol
CA2856403A1 (en) * 2011-11-21 2013-08-15 Neonc Technologies Inc. Pharmaceutical compositions comprising deuterium-enriched perillyl alcohol, iso-perillyl alcohol and derivatives thereof

Similar Documents

Publication Publication Date Title
KR101638035B1 (ko) 핵 수용체에 결합하는 물질
JP5797755B2 (ja) Poh誘導体を含む医薬組成物
TWI664166B (zh) Kcnq2至5通道活化劑
US12109213B2 (en) Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof
RU2711382C2 (ru) 6,7-ДИГИДРОПИРАЗОЛО[1,5-a]ПИРАЗИН-4(5H)-ОНОВЫЕ СОЕДИНЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ОТРИЦАТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ MGLUR2
JP2012514655A (ja) フッ素含有化合物およびその使用法
TWI757726B (zh) 4(1h)-奎諾酮衍生物及其用途
TWI914470B (zh) 稠雜環基取代的環己二醯亞胺衍生物、其製備方法及其在醫藥上的應用
JP2015505301A5 (enExample)
JP2019189644A (ja) 抗癌剤およびその調製方法
WO2017131149A1 (ja) テトラヒドロナフタレン誘導体
JP2015502352A5 (enExample)
WO2013119304A2 (en) Pharmaceutical compositions comprising deuterium-enriched perillyl alcohol, iso-perillyl alcohol and derivatives thereof
CN117062819A (zh) 多环化合物及其用途
TW202114984A (zh) 具有s1p受體作動活性的化合物的鹽及結晶形
JP2022031509A (ja) アンドロゲン依存性又は非依存性前立腺癌細胞の抑制用の組成物及びそれを含有する前立腺癌の医薬製剤
EP3654959A2 (en) Compositions and methods for treatment of central nervous system tumors
JP2011500841A5 (enExample)
RU2010120810A (ru) Гидратированные кристаллические сложные эфиры камптотецина для лечения рака
US11241421B2 (en) Combination therapies for treating cancer
EP3324974B1 (en) Compounds, compositions, methods for treating diseases, and methods for preparing compounds
JPWO2007072749A1 (ja) 鎮咳剤
JP2009249346A (ja) ピリジン骨格を有する血液脳関門透過性化合物
TW202108570A (zh) 抗癌核荷爾蒙受體標靶化合物
TW201231470A (en) 4-anilinofuro[2,3-b]quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same