JP2014500729A5 - - Google Patents

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Publication number
JP2014500729A5
JP2014500729A5 JP2013543299A JP2013543299A JP2014500729A5 JP 2014500729 A5 JP2014500729 A5 JP 2014500729A5 JP 2013543299 A JP2013543299 A JP 2013543299A JP 2013543299 A JP2013543299 A JP 2013543299A JP 2014500729 A5 JP2014500729 A5 JP 2014500729A5
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JP
Japan
Prior art keywords
nucleic acid
target nucleic
inhibitor
detected
conjugated
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JP2013543299A
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English (en)
Japanese (ja)
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JP6096672B2 (ja
JP2014500729A (ja
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Priority claimed from PCT/US2011/063654 external-priority patent/WO2012078710A1/en
Publication of JP2014500729A publication Critical patent/JP2014500729A/ja
Publication of JP2014500729A5 publication Critical patent/JP2014500729A5/ja
Application granted granted Critical
Publication of JP6096672B2 publication Critical patent/JP6096672B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013543299A 2010-12-07 2011-12-07 検出体、プローブ、および阻害剤を用いた核酸標的検出 Expired - Fee Related JP6096672B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42074710P 2010-12-07 2010-12-07
US61/420,747 2010-12-07
PCT/US2011/063654 WO2012078710A1 (en) 2010-12-07 2011-12-07 Nucleic acid target detection using a detector, a probe and an inhibitor

Publications (3)

Publication Number Publication Date
JP2014500729A JP2014500729A (ja) 2014-01-16
JP2014500729A5 true JP2014500729A5 (enExample) 2015-01-29
JP6096672B2 JP6096672B2 (ja) 2017-03-15

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ID=46207491

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013543299A Expired - Fee Related JP6096672B2 (ja) 2010-12-07 2011-12-07 検出体、プローブ、および阻害剤を用いた核酸標的検出

Country Status (8)

Country Link
US (2) US9581549B2 (enExample)
EP (1) EP2649202B1 (enExample)
JP (1) JP6096672B2 (enExample)
CN (2) CN105603071B (enExample)
AU (1) AU2011338502B2 (enExample)
CA (1) CA2820094C (enExample)
SG (1) SG191725A1 (enExample)
WO (1) WO2012078710A1 (enExample)

Families Citing this family (15)

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JP6096672B2 (ja) * 2010-12-07 2017-03-15 ヌビオ，インコーポレイテッド 検出体、プローブ、および阻害剤を用いた核酸標的検出
AU2012236713B2 (en) 2011-03-30 2016-11-24 Bio-Rad Laboratories, Inc. Injection of multiple volumes into or out of droplets
EP2691540B1 (en) 2011-03-31 2016-01-20 GnuBIO, Inc. Managing variation in spectroscopic intensity measurements through the use of a reference component
CA2841425C (en) 2011-03-31 2018-05-01 Gnubio, Inc. Scalable spectroscopic detection and measurement
EP2895591A4 (en) 2012-09-12 2016-10-12 Gnubio Inc INTEGRATED MICROFLUIDIC SYSTEM, METHOD AND KIT FOR PERFORMING TESTS
CN105074303B (zh) 2013-01-25 2018-04-10 基纽拜奥股份有限公司 实施液滴膨胀的系统和方法
CN105408495B (zh) 2013-04-26 2019-01-08 基纽拜奥股份有限公司 通过茎环结构阻断3’dna末端的聚合酶延伸的方法
US9766261B2 (en) 2013-05-29 2017-09-19 Bio-Rad Laboratories, Inc. Low cost optical high speed discrete measurement system
EP3004391B1 (en) * 2013-05-29 2019-03-27 Bio-Rad Laboratories, Inc. Methods for sequencing in emulsion based microfluidics
WO2015031528A1 (en) 2013-08-27 2015-03-05 Gnubio, Inc. Microfluidic devices and methods of their use
US9555411B2 (en) 2013-09-30 2017-01-31 Gnubio, Inc. Microfluidic cartridge devices and methods of use and assembly
US10130950B2 (en) 2013-11-27 2018-11-20 Bio-Rad Laboratories, Inc. Microfluidic droplet packing
WO2016004022A2 (en) 2014-06-30 2016-01-07 Gnubio, Inc. Floating thermal contact enabled pcr
EP3574047B1 (en) 2017-01-30 2024-03-06 Bio-Rad Laboratories, Inc. Emulsion compositions and methods of their use
EP3601593B1 (en) 2017-03-24 2021-12-22 Bio-Rad Laboratories, Inc. Universal hairpin primers

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EP2363205A3 (en) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
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EP2059614A4 (en) * 2006-08-15 2010-06-30 Zygene Biotech Llc ANTISONDON PROBE COMPOSITIONS AND METHODS OF DETECTION OF DNA OR RNA
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WO2008150998A1 (en) * 2007-05-31 2008-12-11 Becton, Dickinson And Company Sequences and methods for detecting influenza a and influenza b virus
EP2235210B1 (en) 2007-12-21 2015-03-25 President and Fellows of Harvard College Methods for nucleic acid sequencing
EP3002489B1 (en) 2008-05-16 2017-09-20 President and Fellows of Harvard College Valves and other flow control in fluidic systems including microfluidic systems
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
EP3587594B1 (en) 2008-12-19 2022-04-13 President and Fellows of Harvard College Particle-assisted nucleic acid sequencing
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
JP5687414B2 (ja) * 2009-04-20 2015-03-18 オリンパス株式会社 多型の識別方法
EP4019977B1 (en) 2009-06-26 2024-11-20 President and Fellows of Harvard College Fluid injection
EP3842150A1 (en) 2009-10-27 2021-06-30 President and Fellows of Harvard College Droplet creation techniques
JP5934657B2 (ja) 2010-02-12 2016-06-15 レインダンス テクノロジーズ， インコーポレイテッド デジタル検体分析
JP6096672B2 (ja) * 2010-12-07 2017-03-15 ヌビオ，インコーポレイテッド 検出体、プローブ、および阻害剤を用いた核酸標的検出
EP3859011A1 (en) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Methods for forming mixed droplets
EP2675819B1 (en) 2011-02-18 2020-04-08 Bio-Rad Laboratories, Inc. Compositions and methods for molecular labeling
AU2012236713B2 (en) 2011-03-30 2016-11-24 Bio-Rad Laboratories, Inc. Injection of multiple volumes into or out of droplets
CA2841425C (en) 2011-03-31 2018-05-01 Gnubio, Inc. Scalable spectroscopic detection and measurement
EP2691540B1 (en) 2011-03-31 2016-01-20 GnuBIO, Inc. Managing variation in spectroscopic intensity measurements through the use of a reference component
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
CN106423314B (zh) 2011-09-28 2021-03-02 哈佛学院院长等 用于液滴产生和/或流体操纵的系统和方法
WO2013122826A1 (en) 2012-02-14 2013-08-22 Gnubio, Inc. Cascaded addition of target specific universal adapters to nucleic acids
EP2844768B1 (en) 2012-04-30 2019-03-13 Raindance Technologies, Inc. Digital analyte analysis
EP2895591A4 (en) 2012-09-12 2016-10-12 Gnubio Inc INTEGRATED MICROFLUIDIC SYSTEM, METHOD AND KIT FOR PERFORMING TESTS
WO2014093976A1 (en) 2012-12-14 2014-06-19 Gnubio, Inc. Method for maintaining heterogeneous concentrations of molecules in emulsion droplets
CN105074303B (zh) 2013-01-25 2018-04-10 基纽拜奥股份有限公司 实施液滴膨胀的系统和方法
CN105408495B (zh) 2013-04-26 2019-01-08 基纽拜奥股份有限公司 通过茎环结构阻断3’dna末端的聚合酶延伸的方法
US9766261B2 (en) 2013-05-29 2017-09-19 Bio-Rad Laboratories, Inc. Low cost optical high speed discrete measurement system
EP3004391B1 (en) 2013-05-29 2019-03-27 Bio-Rad Laboratories, Inc. Methods for sequencing in emulsion based microfluidics
WO2015031528A1 (en) 2013-08-27 2015-03-05 Gnubio, Inc. Microfluidic devices and methods of their use
US9555411B2 (en) 2013-09-30 2017-01-31 Gnubio, Inc. Microfluidic cartridge devices and methods of use and assembly
WO2016004022A2 (en) 2014-06-30 2016-01-07 Gnubio, Inc. Floating thermal contact enabled pcr

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