JP2014500729A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014500729A5 JP2014500729A5 JP2013543299A JP2013543299A JP2014500729A5 JP 2014500729 A5 JP2014500729 A5 JP 2014500729A5 JP 2013543299 A JP2013543299 A JP 2013543299A JP 2013543299 A JP2013543299 A JP 2013543299A JP 2014500729 A5 JP2014500729 A5 JP 2014500729A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- target nucleic
- inhibitor
- detected
- conjugated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42074710P | 2010-12-07 | 2010-12-07 | |
| US61/420,747 | 2010-12-07 | ||
| PCT/US2011/063654 WO2012078710A1 (en) | 2010-12-07 | 2011-12-07 | Nucleic acid target detection using a detector, a probe and an inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014500729A JP2014500729A (ja) | 2014-01-16 |
| JP2014500729A5 true JP2014500729A5 (enExample) | 2015-01-29 |
| JP6096672B2 JP6096672B2 (ja) | 2017-03-15 |
Family
ID=46207491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543299A Expired - Fee Related JP6096672B2 (ja) | 2010-12-07 | 2011-12-07 | 検出体、プローブ、および阻害剤を用いた核酸標的検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9581549B2 (enExample) |
| EP (1) | EP2649202B1 (enExample) |
| JP (1) | JP6096672B2 (enExample) |
| CN (2) | CN105603071B (enExample) |
| AU (1) | AU2011338502B2 (enExample) |
| CA (1) | CA2820094C (enExample) |
| SG (1) | SG191725A1 (enExample) |
| WO (1) | WO2012078710A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2820094C (en) | 2010-12-07 | 2019-02-26 | Gnubio, Inc. | Nucleic acid target detection using fluorophore- and quencher-conjugated oligonucleotides |
| JP6472998B2 (ja) | 2011-03-30 | 2019-02-20 | バイオ−ラッド ラボラトリーズ インコーポレイテッド | 液滴内への、または液滴からの複数の容量の注入 |
| EP2691540B1 (en) | 2011-03-31 | 2016-01-20 | GnuBIO, Inc. | Managing variation in spectroscopic intensity measurements through the use of a reference component |
| WO2012135201A1 (en) | 2011-03-31 | 2012-10-04 | Gnubio, Inc. | Scalable spectroscopic detection and measurement |
| US9821312B2 (en) | 2012-09-12 | 2017-11-21 | Bio-Rad Laboratories, Inc. | Integrated microfluidic system, method and kit for performing assays |
| US9592503B2 (en) | 2013-01-25 | 2017-03-14 | Gnubio, Inc. | System and method for performing droplet inflation |
| EP2989213B1 (en) | 2013-04-26 | 2019-11-06 | Bio-Rad Laboratories, Inc. | A method for blocking polymerase extension of 3 prime dna ends by stem-loop structure |
| EP3004813A4 (en) | 2013-05-29 | 2016-12-21 | Gnubio Inc | COST-EFFECTIVE OPTICAL DISCRETE HIGH-SPEED MEASURING SYSTEM |
| EP3004391B1 (en) | 2013-05-29 | 2019-03-27 | Bio-Rad Laboratories, Inc. | Methods for sequencing in emulsion based microfluidics |
| CN105765055A (zh) | 2013-08-27 | 2016-07-13 | 基纽拜奥股份有限公司 | 微流体装置和其使用方法 |
| EP3052236B1 (en) | 2013-09-30 | 2021-07-14 | Bio-Rad Laboratories, Inc. | Microfluidic cartridge device and methods of use and assembly |
| US10130950B2 (en) | 2013-11-27 | 2018-11-20 | Bio-Rad Laboratories, Inc. | Microfluidic droplet packing |
| US9683792B2 (en) | 2014-06-30 | 2017-06-20 | Bio-Rad Laboratories, Inc. | Floating thermal contact enabled PCR |
| US11118217B2 (en) | 2017-01-30 | 2021-09-14 | Bio-Rad Laboratories, Inc. | Emulsion compositions and methods of their use |
| WO2018175399A1 (en) | 2017-03-24 | 2018-09-27 | Bio-Rad Laboratories, Inc. | Universal hairpin primers |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US6007994A (en) * | 1995-12-22 | 1999-12-28 | Yale University | Multiparametric fluorescence in situ hybridization |
| US6235502B1 (en) * | 1998-09-18 | 2001-05-22 | Molecular Staging Inc. | Methods for selectively isolating DNA using rolling circle amplification |
| US20030148303A1 (en) * | 2000-09-19 | 2003-08-07 | Nadeau James G. | Universal probes and methods for detection of nucleic acids |
| JP4537053B2 (ja) * | 2001-06-25 | 2010-09-01 | ジョージア テック リサーチ コーポレーション | 二重共鳴エネルギー転移核酸プローブ |
| EP2662136A3 (en) | 2003-08-27 | 2013-12-25 | President and Fellows of Harvard College | Method for handling and mixing droplets |
| EP3913375A1 (en) | 2006-01-11 | 2021-11-24 | Bio-Rad Laboratories, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| EP2021113A2 (en) * | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| WO2008021446A2 (en) * | 2006-08-15 | 2008-02-21 | Genetag Technology, Inc. | Probe-antiprobe compositions and methods for dna or rna detection |
| US8568979B2 (en) * | 2006-10-10 | 2013-10-29 | Illumina, Inc. | Compositions and methods for representational selection of nucleic acids from complex mixtures using hybridization |
| US20100129792A1 (en) * | 2007-02-06 | 2010-05-27 | Gerassimos Makrigiorgos | Direct monitoring and pcr amplification of the dosage and dosage difference between target genetic regions |
| EP2152871A4 (en) * | 2007-05-31 | 2011-01-05 | Becton Dickinson Co | SEQUENCES AND METHOD FOR DETECTING INFLUENZA VIRUS A AND INFLUENZA VIRUS B |
| US9797010B2 (en) | 2007-12-21 | 2017-10-24 | President And Fellows Of Harvard College | Systems and methods for nucleic acid sequencing |
| EP2286125B1 (en) | 2008-05-16 | 2015-07-08 | President and Fellows of Harvard College | Valves and other flow control in fluidic systems including microfluidic systems |
| WO2010033200A2 (en) | 2008-09-19 | 2010-03-25 | President And Fellows Of Harvard College | Creation of libraries of droplets and related species |
| EP3290531B1 (en) | 2008-12-19 | 2019-07-24 | President and Fellows of Harvard College | Particle-assisted nucleic acid sequencing |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| JP5687414B2 (ja) * | 2009-04-20 | 2015-03-18 | オリンパス株式会社 | 多型の識別方法 |
| JP5841937B2 (ja) | 2009-06-26 | 2016-01-13 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 流体注入 |
| EP2493619B1 (en) | 2009-10-27 | 2018-12-19 | President and Fellows of Harvard College | Droplet creation techniques |
| EP4484577A3 (en) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| CA2820094C (en) | 2010-12-07 | 2019-02-26 | Gnubio, Inc. | Nucleic acid target detection using fluorophore- and quencher-conjugated oligonucleotides |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| JP6472998B2 (ja) | 2011-03-30 | 2019-02-20 | バイオ−ラッド ラボラトリーズ インコーポレイテッド | 液滴内への、または液滴からの複数の容量の注入 |
| EP2691540B1 (en) | 2011-03-31 | 2016-01-20 | GnuBIO, Inc. | Managing variation in spectroscopic intensity measurements through the use of a reference component |
| WO2012135201A1 (en) | 2011-03-31 | 2012-10-04 | Gnubio, Inc. | Scalable spectroscopic detection and measurement |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| US11389800B2 (en) | 2011-09-28 | 2022-07-19 | President And Fellows Of Harvard College | Systems and methods for droplet production and/or fluidic manipulation |
| US20150045258A1 (en) | 2012-02-14 | 2015-02-12 | Gnubio, Inc. | Cascaded addition of target specific universal adapters to nucleic acids |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| US9821312B2 (en) | 2012-09-12 | 2017-11-21 | Bio-Rad Laboratories, Inc. | Integrated microfluidic system, method and kit for performing assays |
| US20150321163A1 (en) | 2012-12-14 | 2015-11-12 | Gnubio, Inc. | Method for maintaining heterogeneous concentrations of molecules in emulsion droplets |
| US9592503B2 (en) | 2013-01-25 | 2017-03-14 | Gnubio, Inc. | System and method for performing droplet inflation |
| EP2989213B1 (en) | 2013-04-26 | 2019-11-06 | Bio-Rad Laboratories, Inc. | A method for blocking polymerase extension of 3 prime dna ends by stem-loop structure |
| EP3004391B1 (en) | 2013-05-29 | 2019-03-27 | Bio-Rad Laboratories, Inc. | Methods for sequencing in emulsion based microfluidics |
| EP3004813A4 (en) | 2013-05-29 | 2016-12-21 | Gnubio Inc | COST-EFFECTIVE OPTICAL DISCRETE HIGH-SPEED MEASURING SYSTEM |
| CN105765055A (zh) | 2013-08-27 | 2016-07-13 | 基纽拜奥股份有限公司 | 微流体装置和其使用方法 |
| EP3052236B1 (en) | 2013-09-30 | 2021-07-14 | Bio-Rad Laboratories, Inc. | Microfluidic cartridge device and methods of use and assembly |
| US9683792B2 (en) | 2014-06-30 | 2017-06-20 | Bio-Rad Laboratories, Inc. | Floating thermal contact enabled PCR |
-
2011
- 2011-12-07 CA CA2820094A patent/CA2820094C/en active Active
- 2011-12-07 EP EP11846231.6A patent/EP2649202B1/en not_active Not-in-force
- 2011-12-07 SG SG2013043880A patent/SG191725A1/en unknown
- 2011-12-07 WO PCT/US2011/063654 patent/WO2012078710A1/en not_active Ceased
- 2011-12-07 CN CN201610045852.1A patent/CN105603071B/zh not_active Expired - Fee Related
- 2011-12-07 JP JP2013543299A patent/JP6096672B2/ja not_active Expired - Fee Related
- 2011-12-07 US US13/992,187 patent/US9581549B2/en not_active Expired - Fee Related
- 2011-12-07 CN CN201180058333.4A patent/CN103348017B/zh not_active Expired - Fee Related
- 2011-12-07 AU AU2011338502A patent/AU2011338502B2/en not_active Ceased
-
2017
- 2017-01-17 US US15/408,191 patent/US10533212B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014500729A5 (enExample) | ||
| JP2015156872A5 (enExample) | ||
| JP2010529857A5 (enExample) | ||
| FI3122897T3 (fi) | Kohdenukleiinihapposekvenssien detektointi erilaisia detektointilämpötiloja käyttäen | |
| JP2013532494A5 (enExample) | ||
| JP2010227103A5 (enExample) | ||
| JP2016195614A5 (enExample) | ||
| SG194722A1 (en) | Probe based nucleic acid detection | |
| JP2012529904A5 (enExample) | ||
| JP2012518421A5 (enExample) | ||
| NZ598166A (en) | Methods, primers, probes and kits useful for the detection of braf mutations | |
| WO2011103502A3 (en) | Materials and methods for profiling micrornas | |
| WO2012054933A3 (en) | Universal probe assay methods | |
| WO2013009084A3 (ko) | 평행결합 구조의 이중 혼성화 pna 프로브 시스템을 포함하는 실시간 다중 중합효소 연쇄반응에 의한 결핵균 및 비결핵 항산균의 동시 검출용 조성물 및 이를 이용한 검출 방법 | |
| JP2016512437A5 (enExample) | ||
| WO2012129115A3 (en) | Materials and methods for profiling micrornas | |
| WO2012150835A3 (en) | Detection of target nucleic acid sequences by po cleavage and hybridization | |
| JP2014030431A5 (enExample) | ||
| JP2016512041A5 (enExample) | ||
| JP2014530011A5 (enExample) | ||
| WO2012099397A3 (ko) | 실시간 중합효소 연쇄반응을 이용한 표적 유전자의 단일 염기 다형성 판별 방법 및 이를 이용한 표적 유전자의 단일 염기 다형성 판별 키트 | |
| WO2014194318A3 (en) | Real-time pcr point mutation assays for detecting hiv-1 resistance to antiviral drugs | |
| JP2014083052A5 (enExample) | ||
| JP2013519395A5 (enExample) | ||
| WO2012103353A3 (en) | Selective detection of haemophilus influenzae |