JP2014518069A5 - - Google Patents
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- JP2014518069A5 JP2014518069A5 JP2014516047A JP2014516047A JP2014518069A5 JP 2014518069 A5 JP2014518069 A5 JP 2014518069A5 JP 2014516047 A JP2014516047 A JP 2014516047A JP 2014516047 A JP2014516047 A JP 2014516047A JP 2014518069 A5 JP2014518069 A5 JP 2014518069A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- mutations
- sf3b1
- dnmt3a
- asxl1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161498497P | 2011-06-17 | 2011-06-17 | |
| US61/498,497 | 2011-06-17 | ||
| PCT/US2012/042734 WO2012174419A2 (en) | 2011-06-17 | 2012-06-15 | Signatures for predicting the survivability of myelodysplastic syndrome subjects |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014518069A JP2014518069A (ja) | 2014-07-28 |
| JP2014518069A5 true JP2014518069A5 (enExample) | 2015-07-30 |
Family
ID=46420545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516047A Pending JP2014518069A (ja) | 2011-06-17 | 2012-06-15 | 骨髄異形成症候群対象の生存率を予測するための変異シグネチャー |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10711308B2 (enExample) |
| EP (1) | EP2721176A2 (enExample) |
| JP (1) | JP2014518069A (enExample) |
| AU (1) | AU2012271386A1 (enExample) |
| WO (1) | WO2012174419A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2733425A1 (en) | 2008-08-06 | 2010-02-11 | Emergent Product Development Uk Limited | Vaccines against clostridium difficile and methods of use |
| US20140303020A1 (en) * | 2011-08-02 | 2014-10-09 | The University Of Tokyo | Method for Assessing Myelodysplastic Syndrome or Myeloid Tumor Predisposition, Polypeptide and Antibody Therefor, and Candidate Screening Method for Therapeutic Drug or Prophylactic Drug Therefor |
| WO2013151983A1 (en) * | 2012-04-02 | 2013-10-10 | The Cleveland Clinic Foundation | Methods for predicting the prognosis of a subject with a myeloid malignancy |
| WO2014183122A1 (en) * | 2013-05-10 | 2014-11-13 | The Broad Institute, Inc. | Methods for determining response to a hypomethylating agent |
| WO2014193958A2 (en) * | 2013-05-31 | 2014-12-04 | Onconova Therapeutics, Inc. | Methods and compositions for predicting therapeutic efficacy of kinase inhibitors in patients with myelodysplastic syndrome or related disorders |
| WO2015077058A2 (en) | 2013-11-08 | 2015-05-28 | The Broad Institute, Inc. | Compositions and methods for selecting a treatment for b-cell neoplasias |
| CN107002131B (zh) * | 2014-11-12 | 2022-04-29 | 尼欧基因组学实验室股份有限公司 | 作为确认骨髓增生异常综合征诊断的可靠测试的外周血血浆dna深度测序 |
| WO2016085876A1 (en) * | 2014-11-25 | 2016-06-02 | The Broad Institute Inc. | Clonal haematopoiesis |
| WO2016086197A1 (en) | 2014-11-25 | 2016-06-02 | The Brigham And Women's Hospital, Inc. | Method of identifying and treating a person having a predisposition to or afflicted with a cardiometabolic disease |
| EP3347712B1 (en) | 2015-09-11 | 2022-05-11 | The Broad Institute, Inc. | Methods of identifying drug-modulated polypeptide targets for degradation |
| EP3347717A4 (en) | 2015-09-11 | 2019-06-05 | The Brigham and Women's Hospital, Inc. | PROCESS FOR CHARACTERIZING THE RESISTANCE TO CEREBLON MODULATORS |
| WO2018026894A1 (en) * | 2016-08-03 | 2018-02-08 | Celgene Corporation | Methods of treatment of myelodysplastic syndrome |
| JP7093764B2 (ja) * | 2016-08-03 | 2022-06-30 | セルジーン コーポレイション | 骨髄異形成症候群の治療方法 |
| WO2018093797A1 (en) * | 2016-11-15 | 2018-05-24 | The Schepens Eye Research Institute, Inc. | Compositions and methods for the treatment of aberrant angiogenesis |
| KR101934107B1 (ko) * | 2016-12-15 | 2018-12-31 | 가톨릭대학교산학협력단 | 골수형성이상 증후군 환자의 저메틸화 제제 치료 반응성 및 생존 예후 예측용 조성물 |
| EP3710008A4 (en) | 2017-11-14 | 2021-08-25 | The Schepens Eye Research Institute, Inc. | RUNX1 INHIBITION FOR THE TREATMENT OF PROLIFERATIVE VITREORETINOPATHY AND DISEASES ASSOCIATED WITH EPITHELIAL-MESENCHYMAL TRANSITION |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5018067A (en) | 1987-01-12 | 1991-05-21 | Iameter Incorporated | Apparatus and method for improved estimation of health resource consumption through use of diagnostic and/or procedure grouping and severity of illness indicators |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| AU647741B2 (en) | 1989-12-01 | 1994-03-31 | Regents Of The University Of California, The | Methods and compositions for chromosome-specific staining |
| ES2155822T3 (es) | 1990-12-06 | 2001-06-01 | Affymetrix Inc | Compuestos y su utilizacion en una estrategia de sintesis binaria. |
| US5547835A (en) | 1993-01-07 | 1996-08-20 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US20020038227A1 (en) | 2000-02-25 | 2002-03-28 | Fey Christopher T. | Method for centralized health data management |
| US7468032B2 (en) | 2002-12-18 | 2008-12-23 | Cardiac Pacemakers, Inc. | Advanced patient management for identifying, displaying and assisting with correlating health-related data |
| US20040122296A1 (en) | 2002-12-18 | 2004-06-24 | John Hatlestad | Advanced patient management for triaging health-related data |
| WO2010087702A1 (en) * | 2009-01-30 | 2010-08-05 | Stichting Katholieke Universiteit | TET2 gene as a marker for diagnosing a myelodysuplastic syndrome (MDS) or an acute myeloid leukemia (AML) and determining the prognosis in a subject |
-
2012
- 2012-06-15 US US14/125,432 patent/US10711308B2/en active Active
- 2012-06-15 EP EP12731246.0A patent/EP2721176A2/en not_active Withdrawn
- 2012-06-15 WO PCT/US2012/042734 patent/WO2012174419A2/en not_active Ceased
- 2012-06-15 AU AU2012271386A patent/AU2012271386A1/en not_active Abandoned
- 2012-06-15 JP JP2014516047A patent/JP2014518069A/ja active Pending
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