JP2014518069A5 - - Google Patents
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- JP2014518069A5 JP2014518069A5 JP2014516047A JP2014516047A JP2014518069A5 JP 2014518069 A5 JP2014518069 A5 JP 2014518069A5 JP 2014516047 A JP2014516047 A JP 2014516047A JP 2014516047 A JP2014516047 A JP 2014516047A JP 2014518069 A5 JP2014518069 A5 JP 2014518069A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- mutations
- sf3b1
- dnmt3a
- asxl1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161498497P | 2011-06-17 | 2011-06-17 | |
| US61/498,497 | 2011-06-17 | ||
| PCT/US2012/042734 WO2012174419A2 (en) | 2011-06-17 | 2012-06-15 | Signatures for predicting the survivability of myelodysplastic syndrome subjects |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014518069A JP2014518069A (ja) | 2014-07-28 |
| JP2014518069A5 true JP2014518069A5 (enExample) | 2015-07-30 |
Family
ID=46420545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516047A Pending JP2014518069A (ja) | 2011-06-17 | 2012-06-15 | 骨髄異形成症候群対象の生存率を予測するための変異シグネチャー |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10711308B2 (enExample) |
| EP (1) | EP2721176A2 (enExample) |
| JP (1) | JP2014518069A (enExample) |
| AU (1) | AU2012271386A1 (enExample) |
| WO (1) | WO2012174419A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2733425A1 (en) | 2008-08-06 | 2010-02-11 | Emergent Product Development Uk Limited | Vaccines against clostridium difficile and methods of use |
| WO2013018866A1 (ja) * | 2011-08-02 | 2013-02-07 | 国立大学法人東京大学 | 骨髄異形成症候群または骨髄性腫瘍素因の評価方法、そのポリペプチド及び抗体、並びにその治療薬若しくは予防薬の候補物スクリーニング方法 |
| WO2013151983A1 (en) * | 2012-04-02 | 2013-10-10 | The Cleveland Clinic Foundation | Methods for predicting the prognosis of a subject with a myeloid malignancy |
| US11015223B2 (en) | 2013-05-10 | 2021-05-25 | The Regents Of The University Of California | Methods for determining response to a hypomethylating agent |
| AU2014274276A1 (en) * | 2013-05-31 | 2015-12-03 | Onconova Therapeutics, Inc. | Methods and compositions for predicting therapeutic efficacy of kinase inhibitors in patients with myelodysplastic syndrome or related disorders |
| US20160282354A1 (en) | 2013-11-08 | 2016-09-29 | The Broad Institute, Inc. | Compositions and methods for selecting a treatment for b-cell neoplasias |
| JP2017533714A (ja) * | 2014-11-12 | 2017-11-16 | ネオゲノミクス ラボラトリーズ， インコーポレイテッド | 末梢血血漿ｄｎａのディープシーケンシングは、骨髄異形成症候群の診断を確認するうえで信頼性が高い |
| EP3626832B1 (en) | 2014-11-25 | 2024-06-12 | The Brigham and Women's Hospital, Inc. | Method of identifying a person having a predisposition to or afflicted with a cardiometabolic disease |
| WO2016085876A1 (en) * | 2014-11-25 | 2016-06-02 | The Broad Institute Inc. | Clonal haematopoiesis |
| EP3347712B1 (en) | 2015-09-11 | 2022-05-11 | The Broad Institute, Inc. | Methods of identifying drug-modulated polypeptide targets for degradation |
| US11459613B2 (en) | 2015-09-11 | 2022-10-04 | The Brigham And Women's Hospital, Inc. | Methods of characterizing resistance to modulators of Cereblon |
| JP7093764B2 (ja) * | 2016-08-03 | 2022-06-30 | セルジーン コーポレイション | 骨髄異形成症候群の治療方法 |
| EP3493809B1 (en) * | 2016-08-03 | 2023-08-23 | Celgene Corporation | Enasidenib for treatment of myelodysplastic syndrome |
| EP4520828A3 (en) * | 2016-11-15 | 2025-07-09 | The Schepens Eye Research Institute, Inc. | Compositions and methods for the treatment of aberrant angiogenesis |
| KR101934107B1 (ko) * | 2016-12-15 | 2018-12-31 | 가톨릭대학교산학협력단 | 골수형성이상 증후군 환자의 저메틸화 제제 치료 반응성 및 생존 예후 예측용 조성물 |
| JP7416700B2 (ja) | 2017-11-14 | 2024-01-17 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5018067A (en) | 1987-01-12 | 1991-05-21 | Iameter Incorporated | Apparatus and method for improved estimation of health resource consumption through use of diagnostic and/or procedure grouping and severity of illness indicators |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| AU647741B2 (en) | 1989-12-01 | 1994-03-31 | Regents Of The University Of California, The | Methods and compositions for chromosome-specific staining |
| DE69132531T2 (de) | 1990-12-06 | 2001-09-13 | Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) | Verbindungen und ihre Verwendung in einer binären Synthesestrategie |
| DE69433811T2 (de) | 1993-01-07 | 2005-06-23 | Sequenom, Inc., San Diego | Dns - sequenzierung durch massenspektronomie |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US20020038227A1 (en) | 2000-02-25 | 2002-03-28 | Fey Christopher T. | Method for centralized health data management |
| US7468032B2 (en) | 2002-12-18 | 2008-12-23 | Cardiac Pacemakers, Inc. | Advanced patient management for identifying, displaying and assisting with correlating health-related data |
| US20040122296A1 (en) | 2002-12-18 | 2004-06-24 | John Hatlestad | Advanced patient management for triaging health-related data |
| WO2010087702A1 (en) * | 2009-01-30 | 2010-08-05 | Stichting Katholieke Universiteit | TET2 gene as a marker for diagnosing a myelodysuplastic syndrome (MDS) or an acute myeloid leukemia (AML) and determining the prognosis in a subject |
-
2012
- 2012-06-15 AU AU2012271386A patent/AU2012271386A1/en not_active Abandoned
- 2012-06-15 WO PCT/US2012/042734 patent/WO2012174419A2/en not_active Ceased
- 2012-06-15 EP EP12731246.0A patent/EP2721176A2/en not_active Withdrawn
- 2012-06-15 JP JP2014516047A patent/JP2014518069A/ja active Pending
- 2012-06-15 US US14/125,432 patent/US10711308B2/en active Active
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