JP2019516375A5 - - Google Patents

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Publication number
JP2019516375A5
JP2019516375A5 JP2018560186A JP2018560186A JP2019516375A5 JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5 JP 2018560186 A JP2018560186 A JP 2018560186A JP 2018560186 A JP2018560186 A JP 2018560186A JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5
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allele
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nuclear position
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nuclear
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JP2018560186A
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Japanese (ja)
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JP2019516375A (ja
JP7475811B2 (ja
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Priority claimed from PCT/US2017/033625 external-priority patent/WO2017201461A1/en
Publication of JP2019516375A publication Critical patent/JP2019516375A/ja
Publication of JP2019516375A5 publication Critical patent/JP2019516375A5/ja
Priority to JP2022044738A priority Critical patent/JP7392020B2/ja
Priority to JP2023213224A priority patent/JP2024037945A/ja
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Publication of JP7475811B2 publication Critical patent/JP7475811B2/ja
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JP2018560186A 2016-05-20 2017-05-19 遺伝子に基づく炎症性腸疾患の診断 Active JP7475811B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022044738A JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662339357P 2016-05-20 2016-05-20
US62/339,357 2016-05-20
PCT/US2017/033625 WO2017201461A1 (en) 2016-05-20 2017-05-19 Diagnosis of inflammatory bowel disease based on genes

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022044738A Division JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Division JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Publications (3)

Publication Number Publication Date
JP2019516375A JP2019516375A (ja) 2019-06-20
JP2019516375A5 true JP2019516375A5 (enExample) 2020-06-18
JP7475811B2 JP7475811B2 (ja) 2024-04-30

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ID=60326226

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018560186A Active JP7475811B2 (ja) 2016-05-20 2017-05-19 遺伝子に基づく炎症性腸疾患の診断
JP2022044738A Active JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Pending JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022044738A Active JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Pending JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Country Status (6)

Country Link
US (1) US11549146B2 (enExample)
EP (1) EP3458466B1 (enExample)
JP (3) JP7475811B2 (enExample)
KR (4) KR20240095363A (enExample)
CN (2) CN117286238A (enExample)
WO (1) WO2017201461A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
EP3430172A4 (en) 2016-03-17 2019-08-21 Cedars-Sinai Medical Center METHOD FOR DIAGNOSIS OF INFLAMMATORY ENDURANCE THROUGH RNASET2
KR20240095363A (ko) * 2016-05-20 2024-06-25 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
KR20220088529A (ko) 2019-05-14 2022-06-27 프로메테우스 바이오사이언시즈, 인크. Tl1a 환자 선택 방법, 시스템 및 장치
BR112022025667A2 (pt) * 2020-06-26 2023-03-07 Pfizer Métodos de tratamento da doença inflamatória intestinal com anticorpos tl1a
CA3197828A1 (en) * 2020-11-13 2022-05-19 Laurens Kruidenier Methods, systems, and kits for treatment of inflammatory diseases targeting tl1a
CN115851911B (zh) * 2022-11-25 2025-10-24 南京鼓楼医院 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用
EP4646434A2 (en) * 2023-01-06 2025-11-12 Prometheus Biosciences, Inc. Methods of treating inflammatory diseases with combination of tl1a inhibitors and tnf inhibitors
WO2025038473A1 (en) 2023-08-11 2025-02-20 Paragon Therapeutics, Inc. Tl1a binding antibodies and methods of use

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443421A (en) 1982-03-16 1984-04-17 Occidental Chemical Corporation Process for removing particulate impurities from aqueous phosphoric acid
DE3475880D1 (en) 1984-08-27 1989-02-09 Toray Industries Solid-liquid separating apparatus
US5000850A (en) 1986-09-10 1991-03-19 Engelhard Corporation Apparatus for dewatering an aqueous clay suspension
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
JP2002521062A (ja) 1998-07-25 2002-07-16 アストラゼネカ・アクチエボラーグ ヒトニューロキニン1レセプター遺伝子における遺伝子多形性および疾病の診断および処置におけるその使用
JP2004194534A (ja) 2002-12-17 2004-07-15 Sumitomo Pharmaceut Co Ltd 炎症性腸疾患疾患マーカーおよびその利用
CN1890384A (zh) * 2003-10-06 2007-01-03 诺瓦提斯公司 与炎性疾病的治疗功效相关的遗传多态性的用途
EP1815021A2 (en) 2004-11-03 2007-08-08 Almac Diagnostics Limited Transcriptome microarray technology and methods of using the same
US7531637B2 (en) 2005-05-06 2009-05-12 Zymogenetics, Inc. IL-31 monoclonal antibodies
WO2006127900A2 (en) 2005-05-25 2006-11-30 Biogen Idec Ma Inc. Tl1a in the treatment of disease
EP1963534A2 (en) * 2005-12-19 2008-09-03 Genizon Biosciences Inc. Genemap of the human gene associated with crohn's disease
EP2097538A4 (en) 2006-12-07 2011-11-30 Switchgear Genomics TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS
US20110217310A1 (en) * 2007-01-10 2011-09-08 Siegel Richard M Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology
US20080221056A1 (en) * 2007-02-12 2008-09-11 Johns Hopkins University Early Detection and Prognosis of Colon Cancers
US20100190162A1 (en) * 2007-02-26 2010-07-29 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
WO2008106579A2 (en) 2007-02-28 2008-09-04 Cedars-Sinai Medical Center The role of il-12, il-23 and il-17 receptors in inflammatory bowel disease
US20150376707A1 (en) 2007-05-18 2015-12-31 Cedars-Sinai Medical Center Methods of diagnosing and treating inflammatory bowel disease
US8118175B2 (en) 2007-07-18 2012-02-21 Siemens Industry, Inc. Venting device for a disc filter
WO2009039244A2 (en) * 2007-09-18 2009-03-26 Genizon Biosciences Inc. Genemap of the human genes associated with crohn's disease
US20100240043A1 (en) * 2007-10-19 2010-09-23 Cedars-Sinai Medical Center Methods of using genetic variants to diagnose and predict inflammatory bowel disease
JP5745854B2 (ja) 2007-11-13 2015-07-08 テバ バイオファーマシューティカルズ ユーエスエー インコーポレーティッド Tl1aに対するヒト化抗体
NZ710443A (en) 2008-08-12 2019-03-29 Zinfandel Pharmaceuticals Inc Method of identifying disease risk factors
ES2581774T3 (es) 2008-08-29 2016-09-07 Janssen Biotech, Inc. Marcadores y métodos de evaluación y tratamiento de colitis ulcerosa y trastornos relacionados mediante un panel de 20 genes
JP2010088432A (ja) 2008-09-09 2010-04-22 Kansetsu Saisei Kenkyusho:Kk Tnf阻害薬治療による有効性・副作用発現に関する多型、およびその利用
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
WO2010075579A2 (en) * 2008-12-24 2010-07-01 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy
AU2010236568B2 (en) 2009-04-14 2015-08-27 Société des Produits Nestlé S.A. Inflammatory bowel disease prognostics
US20130136720A1 (en) * 2010-01-15 2013-05-30 Cedars-Sinai Medical Center Methods of using fut2 genetic variants to diagnose crohn's disease
JP2013528389A (ja) * 2010-06-04 2013-07-11 ネステク ソシエテ アノニム 炎症性腸疾患の診断を改善させる方法
US8766034B2 (en) 2010-09-22 2014-07-01 Cedars-Sinai Medical Center TL1A model of inflammation fibrosis and autoimmunity
DK2638163T3 (en) 2010-11-12 2017-07-24 Massachusetts Gen Hospital POLYCOMB-ASSOCIATED NON-CODING RNAs
US9902996B2 (en) 2011-02-11 2018-02-27 Cedars-Sinai Medical Center Methods of predicting the need for surgery in crohn's disease
WO2012154987A1 (en) 2011-05-10 2012-11-15 Nestec Sa Methods of disease activity profiling for personalized therapy management
WO2012156515A1 (en) 2011-05-18 2012-11-22 Rheinische Friedrich-Wilhelms-Universität Bonn Molecular analysis of acute myeloid leukemia
JP2014518883A (ja) 2011-05-20 2014-08-07 ガバメント・オブ・ザ・ユナイテッド・ステイツ,アズ・リプリゼンテッド・バイ・ザ・セクレタリー,デパートメント・オブ・ヘルス・アンド・ヒューマン・サーヴィシズ T細胞媒介疾病の病態を改善させるためのtl1a−dr3相互作用の遮断及びその抗体
KR102148982B1 (ko) 2011-06-03 2020-08-27 조마 테크놀로지 리미티드 Tgf-베타에 특이적인 항체
CA2852954A1 (en) 2011-10-21 2013-04-25 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis
EP2812445A2 (en) 2012-02-10 2014-12-17 Novo Nordisk A/S Methods related to treatment of inflammatory diseases and disorders
JP6671276B2 (ja) 2013-03-27 2020-03-25 セダーズ−シナイ メディカル センター Tl1a機能および関連するシグナル経路の抑制による線維症および炎症の緩和および回復
EP2997165A4 (en) 2013-05-17 2017-03-08 Cedars-Sinai Medical Center Variants of tnfsf15 and dcr3 associated with crohn's disease
AU2014331841B2 (en) 2013-10-09 2020-03-12 Cedars-Sinai Medical Center Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease
WO2015138774A1 (en) 2014-03-13 2015-09-17 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US20180305689A1 (en) 2015-04-22 2018-10-25 Mina Therapeutics Limited Sarna compositions and methods of use
TWI737685B (zh) 2016-02-26 2021-09-01 美商奈米科技能源公司 用於處理含碳組合物之方法、裝置及系統
KR20240095363A (ko) * 2016-05-20 2024-06-25 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
WO2018022982A1 (en) 2016-07-29 2018-02-01 Trustees Of Boston University Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
CN110121509B (zh) 2016-10-26 2024-05-07 西达-赛奈医疗中心 中和抗tl1a单克隆抗体
WO2018204764A1 (en) 2017-05-05 2018-11-08 Camp4 Therapeutics Corporation Identification and targeted modulation of gene signaling networks
WO2020121618A1 (ja) 2018-12-14 2020-06-18 株式会社フジクラ フェルール、ファイバ付きフェルール及びファイバ付きフェルールの製造方法

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