JP2019516375A5 - - Google Patents
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- JP2019516375A5 JP2019516375A5 JP2018560186A JP2018560186A JP2019516375A5 JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5 JP 2018560186 A JP2018560186 A JP 2018560186A JP 2018560186 A JP2018560186 A JP 2018560186A JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5
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- JP
- Japan
- Prior art keywords
- allele
- pos
- nuclear position
- snp
- nuclear
- Prior art date
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044738A JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662339357P | 2016-05-20 | 2016-05-20 | |
| US62/339,357 | 2016-05-20 | ||
| PCT/US2017/033625 WO2017201461A1 (en) | 2016-05-20 | 2017-05-19 | Diagnosis of inflammatory bowel disease based on genes |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Division JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Division JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516375A JP2019516375A (ja) | 2019-06-20 |
| JP2019516375A5 true JP2019516375A5 (enExample) | 2020-06-18 |
| JP7475811B2 JP7475811B2 (ja) | 2024-04-30 |
Family
ID=60326226
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560186A Active JP7475811B2 (ja) | 2016-05-20 | 2017-05-19 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A Pending JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A Pending JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11549146B2 (enExample) |
| EP (1) | EP3458466B1 (enExample) |
| JP (4) | JP7475811B2 (enExample) |
| KR (4) | KR20230003433A (enExample) |
| CN (2) | CN109476698B (enExample) |
| WO (1) | WO2017201461A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| KR20230003433A (ko) | 2016-05-20 | 2023-01-05 | 세다르스-신나이 메디칼 센터 | 유전자에 기반한 염증성 장 질환의 진단 |
| WO2020112890A1 (en) | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Rnaset2 compositions and methods of treatment therewith |
| EP3969621A4 (en) | 2019-05-14 | 2023-01-25 | Prometheus Biosciences, Inc. | TL1A PATIENT SELECTION METHODS, SYSTEMS AND DEVICES |
| EP4171632A2 (en) * | 2020-06-26 | 2023-05-03 | Pfizer Inc. | Methods of treating inflammatory bowel disease with tl1a antibodies |
| IL302791A (en) * | 2020-11-13 | 2023-07-01 | Prometheus Biosciences Inc | Methods, systems, and kits for treatment of inflammatory diseases targeting tl1a |
| CN115851911B (zh) * | 2022-11-25 | 2025-10-24 | 南京鼓楼医院 | 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用 |
| WO2024148218A2 (en) * | 2023-01-06 | 2024-07-11 | Prometheus Biosciences, Inc. | Methods of treating inflammatory diseases with combination of tl1a inhibitors and tnf inhibitors |
| IL325993A (en) | 2023-08-11 | 2026-03-01 | Paragon Therapeutics Inc | TL1A binding proteins and methods of use |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443421A (en) | 1982-03-16 | 1984-04-17 | Occidental Chemical Corporation | Process for removing particulate impurities from aqueous phosphoric acid |
| EP0191102B1 (en) | 1984-08-27 | 1989-01-04 | Toray Industries, Inc. | Solid-liquid separating apparatus |
| US5000850A (en) | 1986-09-10 | 1991-03-19 | Engelhard Corporation | Apparatus for dewatering an aqueous clay suspension |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| EP1100962A1 (en) | 1998-07-25 | 2001-05-23 | AstraZeneca AB | Genetic polymorphisms in the human neurokinin 1 receptor gene and their uses in diagnosis and treatment of diseases |
| JP2004194534A (ja) | 2002-12-17 | 2004-07-15 | Sumitomo Pharmaceut Co Ltd | 炎症性腸疾患疾患マーカーおよびその利用 |
| JP2007507460A (ja) * | 2003-10-06 | 2007-03-29 | ノバルティス アクチエンゲゼルシャフト | 炎症性疾患の治療効力と関連している遺伝子多型の使用 |
| JP2008518610A (ja) | 2004-11-03 | 2008-06-05 | アルマック ダイアグノスティックス リミテッド | トランスクリプトームマイクロアレイ技法およびそれを使用する方法 |
| CN101198624B (zh) | 2005-05-06 | 2012-10-10 | 津莫吉尼蒂克斯公司 | Il-31单克隆抗体及使用方法 |
| US20090317388A1 (en) | 2005-05-25 | 2009-12-24 | Linda Burkly | Tl1a in treatment of disease |
| EP1963534A2 (en) * | 2005-12-19 | 2008-09-03 | Genizon Biosciences Inc. | Genemap of the human gene associated with crohn's disease |
| EP2097538A4 (en) | 2006-12-07 | 2011-11-30 | Switchgear Genomics | TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS |
| US20110217310A1 (en) | 2007-01-10 | 2011-09-08 | Siegel Richard M | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology |
| WO2008100913A2 (en) * | 2007-02-12 | 2008-08-21 | The Johns Hopkins University | Early detection and prognosis of colon cancers |
| US20100190162A1 (en) | 2007-02-26 | 2010-07-29 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
| US20100055700A1 (en) | 2007-02-28 | 2010-03-04 | Cedars-Sinai Medical Center | Role of il-12, il-23 and il-17 receptors in inflammatory bowel disease |
| US20150376707A1 (en) | 2007-05-18 | 2015-12-31 | Cedars-Sinai Medical Center | Methods of diagnosing and treating inflammatory bowel disease |
| WO2011088380A1 (en) | 2010-01-15 | 2011-07-21 | Cedars-Sinai Medical Center | Methods of using fut2 genetic variants to diagnose crohn's disease |
| US8118175B2 (en) | 2007-07-18 | 2012-02-21 | Siemens Industry, Inc. | Venting device for a disc filter |
| WO2009039244A2 (en) * | 2007-09-18 | 2009-03-26 | Genizon Biosciences Inc. | Genemap of the human genes associated with crohn's disease |
| WO2009052512A2 (en) | 2007-10-19 | 2009-04-23 | Cedars-Sinai Medical Center | Methods of using genetic variants to diagnose and predict inflammatory bowel disease |
| MX2010005282A (es) | 2007-11-13 | 2010-08-31 | Teva Pharma | Anticuerpos humanizados contra tl1a. |
| KR20160127181A (ko) | 2008-08-12 | 2016-11-02 | 진판델 파마슈티컬스 인코포레이티드 | 질환 위험 인자의 식별 방법 |
| AU2009285644B2 (en) | 2008-08-29 | 2015-08-20 | Janssen Biotech, Inc. | Markers and methods for assessing and treating ulcerative colitis and related disorders using a 20 gene panel |
| JP2010088432A (ja) | 2008-09-09 | 2010-04-22 | Kansetsu Saisei Kenkyusho:Kk | Ｔｎｆ阻害薬治療による有効性・副作用発現に関する多型、およびその利用 |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| WO2010075579A2 (en) | 2008-12-24 | 2010-07-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
| NZ619527A (en) | 2009-04-14 | 2015-06-26 | Nestec Sa | Inflammatory bowel disease prognostics |
| EP2576838A4 (en) * | 2010-06-04 | 2019-05-15 | Nestec S.A. | METHOD FOR IMPROVING DIAGNOSIS OF INFLAMMATORY ENDURANCE |
| US8766034B2 (en) | 2010-09-22 | 2014-07-01 | Cedars-Sinai Medical Center | TL1A model of inflammation fibrosis and autoimmunity |
| EP3702460A1 (en) | 2010-11-12 | 2020-09-02 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| US9902996B2 (en) | 2011-02-11 | 2018-02-27 | Cedars-Sinai Medical Center | Methods of predicting the need for surgery in crohn's disease |
| CA3295783A1 (en) | 2011-05-10 | 2026-03-02 | Prometheus Laboratories, Inc. | Methods of disease activity profiling for personalized therapy management |
| WO2012156515A1 (en) | 2011-05-18 | 2012-11-22 | Rheinische Friedrich-Wilhelms-Universität Bonn | Molecular analysis of acute myeloid leukemia |
| AU2012259312A1 (en) | 2011-05-20 | 2013-12-12 | Government Of The United States, As Represented By The Secretary Department Of Health And Human Services | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof |
| EP2714735B1 (en) | 2011-06-03 | 2021-07-21 | XOMA Technology Ltd. | Antibodies specific for tgf-beta |
| WO2013059732A1 (en) | 2011-10-21 | 2013-04-25 | Nestec S.A. | Methods for improving inflammatory bowel disease diagnosis |
| EP2812445A2 (en) | 2012-02-10 | 2014-12-17 | Novo Nordisk A/S | Methods related to treatment of inflammatory diseases and disorders |
| KR20240122922A (ko) | 2013-03-27 | 2024-08-13 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| KR20210107176A (ko) * | 2013-05-17 | 2021-08-31 | 세다르스-신나이 메디칼 센터 | 크론병과 연관된 tnfsf15와 dcr3의 변이체 |
| NZ717633A (en) * | 2013-10-09 | 2021-07-30 | Cedars Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| WO2015138774A1 (en) * | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP3286318A2 (en) | 2015-04-22 | 2018-02-28 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| MX2018010266A (es) | 2016-02-26 | 2019-03-28 | Nanotech Energy Inc | Métodos, dispositivos y sistemas para procesamiento de composiciones carbonosas. |
| KR20230003433A (ko) * | 2016-05-20 | 2023-01-05 | 세다르스-신나이 메디칼 센터 | 유전자에 기반한 염증성 장 질환의 진단 |
| US10041044B2 (en) | 2016-07-29 | 2018-08-07 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
| MY191324A (en) | 2016-10-26 | 2022-06-15 | Cedars Sinai Medical Center | Neutralizing anti-tl1a monoclonal antibodies |
| US20210254056A1 (en) | 2017-05-05 | 2021-08-19 | Camp4 Therapeutics Corporation | Identification and targeted modulation of gene signaling networks |
| US11675142B2 (en) | 2018-12-14 | 2023-06-13 | Fujikura Ltd. | Ferrule, fiber-equipped ferrule, and method for manufacturing fiber-equipped ferrule |
-
2017
- 2017-05-19 KR KR1020227044940A patent/KR20230003433A/ko not_active Ceased
- 2017-05-19 EP EP17800279.6A patent/EP3458466B1/en active Active
- 2017-05-19 KR KR1020247019512A patent/KR20240095363A/ko not_active Ceased
- 2017-05-19 KR KR1020227003985A patent/KR102481305B1/ko active Active
- 2017-05-19 US US16/303,033 patent/US11549146B2/en active Active
- 2017-05-19 KR KR1020187037151A patent/KR20190016972A/ko not_active Ceased
- 2017-05-19 CN CN201780044934.7A patent/CN109476698B/zh active Active
- 2017-05-19 CN CN202311263442.0A patent/CN117286238A/zh active Pending
- 2017-05-19 WO PCT/US2017/033625 patent/WO2017201461A1/en not_active Ceased
- 2017-05-19 JP JP2018560186A patent/JP7475811B2/ja active Active
-
2022
- 2022-03-18 JP JP2022044738A patent/JP7392020B2/ja active Active
- 2022-12-09 US US18/063,931 patent/US12545959B2/en active Active
-
2023
- 2023-12-18 JP JP2023213224A patent/JP2024037945A/ja active Pending
-
2025
- 2025-11-25 JP JP2025203084A patent/JP2026048696A/ja active Pending
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