JP2019516375A5 - - Google Patents
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- JP2019516375A5 JP2019516375A5 JP2018560186A JP2018560186A JP2019516375A5 JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5 JP 2018560186 A JP2018560186 A JP 2018560186A JP 2018560186 A JP2018560186 A JP 2018560186A JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5
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- Japan
- Prior art keywords
- allele
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- nuclear
- Prior art date
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044738A JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662339357P | 2016-05-20 | 2016-05-20 | |
| US62/339,357 | 2016-05-20 | ||
| PCT/US2017/033625 WO2017201461A1 (en) | 2016-05-20 | 2017-05-19 | Diagnosis of inflammatory bowel disease based on genes |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Division JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Division JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516375A JP2019516375A (ja) | 2019-06-20 |
| JP2019516375A5 true JP2019516375A5 (enExample) | 2020-06-18 |
| JP7475811B2 JP7475811B2 (ja) | 2024-04-30 |
Family
ID=60326226
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560186A Active JP7475811B2 (ja) | 2016-05-20 | 2017-05-19 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A Pending JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2025203084A Pending JP2026048696A (ja) | 2016-05-20 | 2025-11-25 | 遺伝子に基づく炎症性腸疾患の診断 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11549146B2 (enExample) |
| EP (1) | EP3458466B1 (enExample) |
| JP (4) | JP7475811B2 (enExample) |
| KR (4) | KR20230003433A (enExample) |
| CN (2) | CN109476698B (enExample) |
| WO (1) | WO2017201461A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| KR20180127416A (ko) | 2016-03-17 | 2018-11-28 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
| CN109476698B (zh) * | 2016-05-20 | 2023-10-17 | 西达-赛奈医疗中心 | 基于基因的炎性肠病诊断 |
| CA3121162A1 (en) | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Rnaset2 compositions and methods of treatment therewith |
| CN114375339A (zh) | 2019-05-14 | 2022-04-19 | 普罗米修斯生物科学公司 | Tl1a患者选择方法、系统和装置 |
| CN116322762A (zh) * | 2020-06-26 | 2023-06-23 | 辉瑞公司 | 用tl1a抗体治疗炎症性肠病的方法 |
| JP2023551602A (ja) * | 2020-11-13 | 2023-12-08 | プロメテウス バイオサイエンシーズ,インク. | Tl1aを標的とする炎症性疾患の治療のための方法、システム、およびキット |
| CN115851911B (zh) * | 2022-11-25 | 2025-10-24 | 南京鼓楼医院 | 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用 |
| EP4646434A2 (en) * | 2023-01-06 | 2025-11-12 | Prometheus Biosciences, Inc. | Methods of treating inflammatory diseases with combination of tl1a inhibitors and tnf inhibitors |
| IL325993A (en) | 2023-08-11 | 2026-03-01 | Paragon Therapeutics Inc | TL1A binding proteins and methods of use |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443421A (en) | 1982-03-16 | 1984-04-17 | Occidental Chemical Corporation | Process for removing particulate impurities from aqueous phosphoric acid |
| DE3475880D1 (en) | 1984-08-27 | 1989-02-09 | Toray Industries | Solid-liquid separating apparatus |
| US5000850A (en) | 1986-09-10 | 1991-03-19 | Engelhard Corporation | Apparatus for dewatering an aqueous clay suspension |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| JP2002521062A (ja) * | 1998-07-25 | 2002-07-16 | アストラゼネカ・アクチエボラーグ | ヒトニューロキニン1レセプター遺伝子における遺伝子多形性および疾病の診断および処置におけるその使用 |
| JP2004194534A (ja) | 2002-12-17 | 2004-07-15 | Sumitomo Pharmaceut Co Ltd | 炎症性腸疾患疾患マーカーおよびその利用 |
| CN1890384A (zh) * | 2003-10-06 | 2007-01-03 | 诺瓦提斯公司 | 与炎性疾病的治疗功效相关的遗传多态性的用途 |
| US20060134663A1 (en) | 2004-11-03 | 2006-06-22 | Paul Harkin | Transcriptome microarray technology and methods of using the same |
| BRPI0611069A2 (pt) | 2005-05-06 | 2010-11-09 | Zymogenetics Inc | anticorpo monoclonal, anticorpo humanizado, fragmento de anticorpo, uso de um antagonista, e, hibridoma |
| WO2006127900A2 (en) | 2005-05-25 | 2006-11-30 | Biogen Idec Ma Inc. | Tl1a in the treatment of disease |
| CA2634146A1 (en) * | 2005-12-19 | 2007-06-28 | Genizon Biosciences Inc. | Genemap of the human genes associated with crohn's disease |
| US20090018031A1 (en) | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
| US20110217310A1 (en) * | 2007-01-10 | 2011-09-08 | Siegel Richard M | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology |
| US20080221056A1 (en) * | 2007-02-12 | 2008-09-11 | Johns Hopkins University | Early Detection and Prognosis of Colon Cancers |
| US20100190162A1 (en) * | 2007-02-26 | 2010-07-29 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
| US20100055700A1 (en) | 2007-02-28 | 2010-03-04 | Cedars-Sinai Medical Center | Role of il-12, il-23 and il-17 receptors in inflammatory bowel disease |
| WO2011088380A1 (en) * | 2010-01-15 | 2011-07-21 | Cedars-Sinai Medical Center | Methods of using fut2 genetic variants to diagnose crohn's disease |
| US20150376707A1 (en) * | 2007-05-18 | 2015-12-31 | Cedars-Sinai Medical Center | Methods of diagnosing and treating inflammatory bowel disease |
| US8118175B2 (en) | 2007-07-18 | 2012-02-21 | Siemens Industry, Inc. | Venting device for a disc filter |
| WO2009039244A2 (en) * | 2007-09-18 | 2009-03-26 | Genizon Biosciences Inc. | Genemap of the human genes associated with crohn's disease |
| WO2009052512A2 (en) * | 2007-10-19 | 2009-04-23 | Cedars-Sinai Medical Center | Methods of using genetic variants to diagnose and predict inflammatory bowel disease |
| MX2010005282A (es) | 2007-11-13 | 2010-08-31 | Teva Pharma | Anticuerpos humanizados contra tl1a. |
| PE20110565A1 (es) * | 2008-08-12 | 2011-09-02 | Zinfandel Pharmaceuticals Inc | Metodo de identificacion de factores de riesgo de la enfermedad |
| WO2010025340A2 (en) | 2008-08-29 | 2010-03-04 | Centocor Ortho Biotech Inc. | Markers and methods for assessing and treating ulcerative colitis and related disorders using a 20 gene panel |
| JP2010088432A (ja) | 2008-09-09 | 2010-04-22 | Kansetsu Saisei Kenkyusho:Kk | Tnf阻害薬治療による有効性・副作用発現に関する多型、およびその利用 |
| WO2010062960A2 (en) * | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| WO2010075579A2 (en) | 2008-12-24 | 2010-07-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
| NZ595471A (en) | 2009-04-14 | 2014-01-31 | Nestec Sa | Inflammatory bowel disease prognostics |
| JP2013528389A (ja) * | 2010-06-04 | 2013-07-11 | ネステク ソシエテ アノニム | 炎症性腸疾患の診断を改善させる方法 |
| US8766034B2 (en) | 2010-09-22 | 2014-07-01 | Cedars-Sinai Medical Center | TL1A model of inflammation fibrosis and autoimmunity |
| AU2011325956B2 (en) | 2010-11-12 | 2016-07-14 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
| US9902996B2 (en) * | 2011-02-11 | 2018-02-27 | Cedars-Sinai Medical Center | Methods of predicting the need for surgery in crohn's disease |
| WO2012154987A1 (en) | 2011-05-10 | 2012-11-15 | Nestec Sa | Methods of disease activity profiling for personalized therapy management |
| WO2012156515A1 (en) | 2011-05-18 | 2012-11-22 | Rheinische Friedrich-Wilhelms-Universität Bonn | Molecular analysis of acute myeloid leukemia |
| AU2012259312A1 (en) | 2011-05-20 | 2013-12-12 | Government Of The United States, As Represented By The Secretary Department Of Health And Human Services | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof |
| PH12013502489B1 (en) | 2011-06-03 | 2019-04-24 | Xoma Technology Ltd | Antibodies specific for tgf-beta |
| EP2769321B1 (en) | 2011-10-21 | 2016-06-01 | Nestec S.A. | Methods for improving inflammatory bowel disease diagnosis |
| KR20140124767A (ko) * | 2012-02-10 | 2014-10-27 | 노보 노르디스크 에이/에스 | 염증성 질환 및 장애의 치료에 관한 방법 |
| KR20230109779A (ko) | 2013-03-27 | 2023-07-20 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전 |
| CN105358713B (zh) * | 2013-05-17 | 2020-02-28 | 雪松-西奈医学中心 | 与克罗恩病相关的tnfsf15和dcr3的变体 |
| CA2923651C (en) | 2013-10-09 | 2023-03-14 | Cedars-Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| US11365447B2 (en) * | 2014-03-13 | 2022-06-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20180305689A1 (en) | 2015-04-22 | 2018-10-25 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| TWI737685B (zh) | 2016-02-26 | 2021-09-01 | 美商奈米科技能源公司 | 用於處理含碳組合物之方法、裝置及系統 |
| CN109476698B (zh) | 2016-05-20 | 2023-10-17 | 西达-赛奈医疗中心 | 基于基因的炎性肠病诊断 |
| WO2018022982A1 (en) | 2016-07-29 | 2018-02-01 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
| CN118240830A (zh) | 2016-10-26 | 2024-06-25 | 西达-赛奈医疗中心 | 中和抗tl1a单克隆抗体 |
| US20210254056A1 (en) | 2017-05-05 | 2021-08-19 | Camp4 Therapeutics Corporation | Identification and targeted modulation of gene signaling networks |
| WO2020121618A1 (ja) | 2018-12-14 | 2020-06-18 | 株式会社フジクラ | フェルール、ファイバ付きフェルール及びファイバ付きフェルールの製造方法 |
-
2017
- 2017-05-19 CN CN201780044934.7A patent/CN109476698B/zh active Active
- 2017-05-19 KR KR1020227044940A patent/KR20230003433A/ko not_active Ceased
- 2017-05-19 WO PCT/US2017/033625 patent/WO2017201461A1/en not_active Ceased
- 2017-05-19 KR KR1020187037151A patent/KR20190016972A/ko not_active Ceased
- 2017-05-19 KR KR1020247019512A patent/KR20240095363A/ko not_active Ceased
- 2017-05-19 US US16/303,033 patent/US11549146B2/en active Active
- 2017-05-19 JP JP2018560186A patent/JP7475811B2/ja active Active
- 2017-05-19 CN CN202311263442.0A patent/CN117286238A/zh active Pending
- 2017-05-19 KR KR1020227003985A patent/KR102481305B1/ko active Active
- 2017-05-19 EP EP17800279.6A patent/EP3458466B1/en active Active
-
2022
- 2022-03-18 JP JP2022044738A patent/JP7392020B2/ja active Active
- 2022-12-09 US US18/063,931 patent/US12545959B2/en active Active
-
2023
- 2023-12-18 JP JP2023213224A patent/JP2024037945A/ja active Pending
-
2025
- 2025-11-25 JP JP2025203084A patent/JP2026048696A/ja active Pending
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