JP2019516375A5 - - Google Patents

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Publication number
JP2019516375A5
JP2019516375A5 JP2018560186A JP2018560186A JP2019516375A5 JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5 JP 2018560186 A JP2018560186 A JP 2018560186A JP 2018560186 A JP2018560186 A JP 2018560186A JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5
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Japan
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allele
pos
nuclear position
snp
nuclear
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JP2018560186A
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Japanese (ja)
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JP2019516375A (ja
JP7475811B2 (ja
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Priority claimed from PCT/US2017/033625 external-priority patent/WO2017201461A1/en
Publication of JP2019516375A publication Critical patent/JP2019516375A/ja
Publication of JP2019516375A5 publication Critical patent/JP2019516375A5/ja
Priority to JP2022044738A priority Critical patent/JP7392020B2/ja
Priority to JP2023213224A priority patent/JP2024037945A/ja
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Publication of JP7475811B2 publication Critical patent/JP7475811B2/ja
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JP2018560186A 2016-05-20 2017-05-19 遺伝子に基づく炎症性腸疾患の診断 Active JP7475811B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022044738A JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662339357P 2016-05-20 2016-05-20
US62/339,357 2016-05-20
PCT/US2017/033625 WO2017201461A1 (en) 2016-05-20 2017-05-19 Diagnosis of inflammatory bowel disease based on genes

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2022044738A Division JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Division JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Publications (3)

Publication Number Publication Date
JP2019516375A JP2019516375A (ja) 2019-06-20
JP2019516375A5 true JP2019516375A5 (enExample) 2020-06-18
JP7475811B2 JP7475811B2 (ja) 2024-04-30

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ID=60326226

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018560186A Active JP7475811B2 (ja) 2016-05-20 2017-05-19 遺伝子に基づく炎症性腸疾患の診断
JP2022044738A Active JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Pending JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022044738A Active JP7392020B2 (ja) 2016-05-20 2022-03-18 遺伝子に基づく炎症性腸疾患の診断
JP2023213224A Pending JP2024037945A (ja) 2016-05-20 2023-12-18 遺伝子に基づく炎症性腸疾患の診断

Country Status (6)

Country Link
US (2) US11549146B2 (enExample)
EP (1) EP3458466B1 (enExample)
JP (3) JP7475811B2 (enExample)
KR (4) KR102481305B1 (enExample)
CN (2) CN109476698B (enExample)
WO (1) WO2017201461A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法
KR102481305B1 (ko) * 2016-05-20 2022-12-26 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
WO2020232125A1 (en) 2019-05-14 2020-11-19 Prometheus Biosciences, Inc. Tl1a patient selection methods, systems, and devices
EP4171632A2 (en) * 2020-06-26 2023-05-03 Pfizer Inc. Methods of treating inflammatory bowel disease with tl1a antibodies
WO2022103961A1 (en) * 2020-11-13 2022-05-19 Prometheus Biosciences, Inc. Methods, systems, and kits for treatment of inflammatory diseases targeting tl1a
CN115851911B (zh) * 2022-11-25 2025-10-24 南京鼓楼医院 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用
WO2024148218A2 (en) * 2023-01-06 2024-07-11 Prometheus Biosciences, Inc. Methods of treating inflammatory diseases with combination of tl1a inhibitors and tnf inhibitors
WO2025038473A1 (en) 2023-08-11 2025-02-20 Paragon Therapeutics, Inc. Tl1a binding antibodies and methods of use

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443421A (en) 1982-03-16 1984-04-17 Occidental Chemical Corporation Process for removing particulate impurities from aqueous phosphoric acid
EP0191102B1 (en) 1984-08-27 1989-01-04 Toray Industries, Inc. Solid-liquid separating apparatus
US5000850A (en) 1986-09-10 1991-03-19 Engelhard Corporation Apparatus for dewatering an aqueous clay suspension
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
JP2002521062A (ja) * 1998-07-25 2002-07-16 アストラゼネカ・アクチエボラーグ ヒトニューロキニン１レセプター遺伝子における遺伝子多形性および疾病の診断および処置におけるその使用
JP2004194534A (ja) 2002-12-17 2004-07-15 Sumitomo Pharmaceut Co Ltd 炎症性腸疾患疾患マーカーおよびその利用
WO2005040416A1 (en) * 2003-10-06 2005-05-06 Novartis Ag Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
AU2005300688B2 (en) 2004-11-03 2012-02-02 Almac Diagnostics Limited Transcriptome microarray technology and methods of using the same
JP5065253B2 (ja) 2005-05-06 2012-10-31 ザイモジェネティクス， インコーポレイテッド Ｉｌ−３１モノクローナル抗体とその使用法
WO2006127900A2 (en) 2005-05-25 2006-11-30 Biogen Idec Ma Inc. Tl1a in the treatment of disease
EP1963534A2 (en) * 2005-12-19 2008-09-03 Genizon Biosciences Inc. Genemap of the human gene associated with crohn's disease
EP2097538A4 (en) 2006-12-07 2011-11-30 Switchgear Genomics TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS
US20110217310A1 (en) * 2007-01-10 2011-09-08 Siegel Richard M Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology
CA2676227A1 (en) * 2007-02-12 2008-08-21 The Johns Hopkins University Early detection and prognosis of colon cancers
WO2008106451A2 (en) 2007-02-26 2008-09-04 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
WO2008106579A2 (en) 2007-02-28 2008-09-04 Cedars-Sinai Medical Center The role of il-12, il-23 and il-17 receptors in inflammatory bowel disease
US20150376707A1 (en) 2007-05-18 2015-12-31 Cedars-Sinai Medical Center Methods of diagnosing and treating inflammatory bowel disease
US8118175B2 (en) 2007-07-18 2012-02-21 Siemens Industry, Inc. Venting device for a disc filter
WO2009039244A2 (en) * 2007-09-18 2009-03-26 Genizon Biosciences Inc. Genemap of the human genes associated with crohn's disease
WO2009052512A2 (en) * 2007-10-19 2009-04-23 Cedars-Sinai Medical Center Methods of using genetic variants to diagnose and predict inflammatory bowel disease
CA2705292C (en) 2007-11-13 2016-06-21 Teva Biopharmaceuticals Usa, Inc. Humanized antibodies against tl1a
NZ710443A (en) * 2008-08-12 2019-03-29 Zinfandel Pharmaceuticals Inc Method of identifying disease risk factors
CN102165315B (zh) 2008-08-29 2014-06-18 森托科尔奥索生物科技公司 用于使用20基因群组评估及治疗溃疡性结肠炎和相关疾病的标记物和方法
JP2010088432A (ja) 2008-09-09 2010-04-22 Kansetsu Saisei Kenkyusho:Kk Ｔｎｆ阻害薬治療による有効性・副作用発現に関する多型、およびその利用
US20110229471A1 (en) * 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
CA2758531C (en) 2009-04-14 2018-11-13 Derren Barken Inflammatory bowel disease prognostics
US20130136720A1 (en) 2010-01-15 2013-05-30 Cedars-Sinai Medical Center Methods of using fut2 genetic variants to diagnose crohn's disease
EP2576838A4 (en) * 2010-06-04 2019-05-15 Nestec S.A. METHOD FOR IMPROVING DIAGNOSIS OF INFLAMMATORY ENDURANCE
US8766034B2 (en) 2010-09-22 2014-07-01 Cedars-Sinai Medical Center TL1A model of inflammation fibrosis and autoimmunity
DK2638163T3 (en) 2010-11-12 2017-07-24 Massachusetts Gen Hospital POLYCOMB-ASSOCIATED NON-CODING RNAs
US9902996B2 (en) * 2011-02-11 2018-02-27 Cedars-Sinai Medical Center Methods of predicting the need for surgery in crohn's disease
WO2012154987A1 (en) 2011-05-10 2012-11-15 Nestec Sa Methods of disease activity profiling for personalized therapy management
EP2710147A1 (en) 2011-05-18 2014-03-26 Rheinische Friedrich-Wilhelms-Universität Bonn Molecular analysis of acute myeloid leukemia
WO2012161856A1 (en) 2011-05-20 2012-11-29 Government Of The United States, As Represented By The Secretary, Department Of Health And Human Services Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology and antibodies thereof
AU2012261933B2 (en) 2011-06-03 2017-06-15 Xoma Technology Ltd. Antibodies specific for TGF-beta
SG11201401536QA (en) * 2011-10-21 2014-05-29 Nestec Sa Methods for improving inflammatory bowel disease diagnosis
EP2812445A2 (en) * 2012-02-10 2014-12-17 Novo Nordisk A/S Methods related to treatment of inflammatory diseases and disorders
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
KR102295125B1 (ko) * 2013-05-17 2021-08-31 세다르스-신나이 메디칼 센터 크론병과 연관된 tnfsf15와 dcr3의 변이체
AU2014331841B2 (en) 2013-10-09 2020-03-12 Cedars-Sinai Medical Center Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease
EP3117011B1 (en) * 2014-03-13 2020-05-06 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
JP2018512876A (ja) 2015-04-22 2018-05-24 ミナ セラピューティクス リミテッド ｓａＲＮＡ組成物および使用方法
WO2017147468A1 (en) 2016-02-26 2017-08-31 Nanotech Energy, Inc. Methods, devices and systems for processing of carbonaceous compositions
KR102481305B1 (ko) * 2016-05-20 2022-12-26 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
WO2018022982A1 (en) 2016-07-29 2018-02-01 Trustees Of Boston University Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
SG11201903737PA (en) 2016-10-26 2019-05-30 Cedars Sinai Medical Center Neutralizing anti-tl1a monoclonal antibodies
WO2018204764A1 (en) 2017-05-05 2018-11-08 Camp4 Therapeutics Corporation Identification and targeted modulation of gene signaling networks
WO2020121618A1 (ja) 2018-12-14 2020-06-18 株式会社フジクラ フェルール、ファイバ付きフェルール及びファイバ付きフェルールの製造方法

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