JP2013544536A5 - - Google Patents
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- Publication number
- JP2013544536A5 JP2013544536A5 JP2013543383A JP2013543383A JP2013544536A5 JP 2013544536 A5 JP2013544536 A5 JP 2013544536A5 JP 2013543383 A JP2013543383 A JP 2013543383A JP 2013543383 A JP2013543383 A JP 2013543383A JP 2013544536 A5 JP2013544536 A5 JP 2013544536A5
- Authority
- JP
- Japan
- Prior art keywords
- il1b
- allele
- copies
- patient
- copy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000028169 periodontal disease Diseases 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 15
- 239000012472 biological sample Substances 0.000 claims description 6
- 239000013068 control sample Substances 0.000 claims description 2
- 101001033249 Homo sapiens Interleukin-1 beta Proteins 0.000 claims 92
- 102100039065 Interleukin-1 beta Human genes 0.000 claims 92
- 108700028369 Alleles Proteins 0.000 claims 89
- 239000002131 composite material Substances 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 102000054766 genetic haplotypes Human genes 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 101150012417 IL1B gene Proteins 0.000 claims 1
- 238000007689 inspection Methods 0.000 claims 1
- 102000054765 polymorphisms of proteins Human genes 0.000 claims 1
- 230000002250 progressing effect Effects 0.000 claims 1
- 206010071602 Genetic polymorphism Diseases 0.000 description 6
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000003205 genotyping method Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42162810P | 2010-12-09 | 2010-12-09 | |
| US61/421,628 | 2010-12-09 | ||
| US201161452157P | 2011-03-13 | 2011-03-13 | |
| US61/452,157 | 2011-03-13 | ||
| PCT/US2011/064216 WO2012079010A2 (en) | 2010-12-09 | 2011-12-09 | Improved method and kit for determining severity and progression of periodontal disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017008513A Division JP6622731B2 (ja) | 2010-12-09 | 2017-01-20 | 歯周病の重症度および進行を決定するための改良された方法およびキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544536A JP2013544536A (ja) | 2013-12-19 |
| JP2013544536A5 true JP2013544536A5 (enExample) | 2015-02-05 |
| JP6138692B2 JP6138692B2 (ja) | 2017-05-31 |
Family
ID=46207769
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543383A Active JP6138692B2 (ja) | 2010-12-09 | 2011-12-09 | 歯周病の重症度および進行を決定するための改良された方法およびキット |
| JP2017008513A Active JP6622731B2 (ja) | 2010-12-09 | 2017-01-20 | 歯周病の重症度および進行を決定するための改良された方法およびキット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017008513A Active JP6622731B2 (ja) | 2010-12-09 | 2017-01-20 | 歯周病の重症度および進行を決定するための改良された方法およびキット |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20120208187A1 (enExample) |
| EP (1) | EP2649203B1 (enExample) |
| JP (2) | JP6138692B2 (enExample) |
| CN (1) | CN103547680B (enExample) |
| AU (2) | AU2011338210B2 (enExample) |
| BR (1) | BR112013014479B1 (enExample) |
| NZ (2) | NZ701432A (enExample) |
| RU (2) | RU2018122965A (enExample) |
| SG (1) | SG191078A1 (enExample) |
| WO (1) | WO2012079010A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106918706B (zh) * | 2015-12-25 | 2019-05-21 | 广州瑞博奥生物科技有限公司 | 一种检测牙周病相关蛋白的抗体芯片试剂盒 |
| CA3011363A1 (en) | 2016-01-12 | 2017-07-20 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| GB201818627D0 (en) * | 2018-11-15 | 2019-01-02 | Mars Inc | Analytical systems |
| JP7097855B2 (ja) * | 2019-04-24 | 2022-07-08 | ジェネシスヘルスケア株式会社 | 歯周病のリスクを判定する方法 |
| CA3142662A1 (en) | 2019-06-06 | 2020-12-10 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
| KR102571131B1 (ko) * | 2021-06-01 | 2023-08-24 | 부산대학교 산학협력단 | 치주염 감별용 바이오마커 조성물, 치주염 중증도 감별용 바이오마커 조성물, 및 이를 이용한 진단 키트 |
| EP4430621A1 (en) * | 2021-11-12 | 2024-09-18 | Mars, Incorporated | Systems and methods for generating health reports based on veterinary oral care health test |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5110920A (en) | 1982-01-22 | 1992-05-05 | Cetus Corporation | HLA typing method and DNA probes used therein |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5268267A (en) | 1987-08-21 | 1993-12-07 | The General Hospital Corporation | Method for diagnosing small cell carcinoma |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5328829A (en) | 1990-07-05 | 1994-07-12 | Forsyth Dental Infirmary For Children | Method of determining sites of active periodontal disease |
| US5686246A (en) * | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| US20050282198A1 (en) * | 1997-05-29 | 2005-12-22 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype |
| US6130042A (en) * | 1998-03-05 | 2000-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for diagnosing periodontal disease |
| ES2356167T3 (es) * | 2004-05-03 | 2011-04-05 | Interleukin Genetics, Inc. | Método de diagnóstico y terapia para enfermedades asociadas con un haplotipo inflamatorio il-1. |
| US20080118920A1 (en) * | 2004-05-03 | 2008-05-22 | Duff Gordon W | Diagnostics And Therapeutics For Diseases Associated With An Il-1 Inflammatory Haplotype |
| EP2304052A2 (en) * | 2008-05-02 | 2011-04-06 | Interleukin Genetics, Inc. | Detecting genetic predisposition to osteoarthritis associated conditions |
-
2011
- 2011-12-09 SG SG2013044383A patent/SG191078A1/en unknown
- 2011-12-09 CN CN201180067082.6A patent/CN103547680B/zh not_active Expired - Fee Related
- 2011-12-09 RU RU2018122965A patent/RU2018122965A/ru not_active Application Discontinuation
- 2011-12-09 BR BR112013014479-3A patent/BR112013014479B1/pt not_active IP Right Cessation
- 2011-12-09 NZ NZ701432A patent/NZ701432A/en not_active IP Right Cessation
- 2011-12-09 WO PCT/US2011/064216 patent/WO2012079010A2/en not_active Ceased
- 2011-12-09 US US13/316,198 patent/US20120208187A1/en not_active Abandoned
- 2011-12-09 RU RU2013131239A patent/RU2664431C2/ru not_active IP Right Cessation
- 2011-12-09 AU AU2011338210A patent/AU2011338210B2/en not_active Ceased
- 2011-12-09 EP EP11846577.2A patent/EP2649203B1/en not_active Not-in-force
- 2011-12-09 NZ NZ612799A patent/NZ612799A/en not_active IP Right Cessation
- 2011-12-09 JP JP2013543383A patent/JP6138692B2/ja active Active
-
2013
- 2013-08-08 US US13/962,637 patent/US9347090B2/en active Active
-
2016
- 2016-04-08 AU AU2016202211A patent/AU2016202211B2/en not_active Ceased
- 2016-05-02 US US15/144,263 patent/US20160244841A1/en not_active Abandoned
-
2017
- 2017-01-20 JP JP2017008513A patent/JP6622731B2/ja active Active
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